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F420 biosynthesis protein FbiB, C-terminal domain Coenzyme F420 differs between the Archaea and the Actinobacteria, where the numbers of glutamate residues attached are 2 (Archaea) or 5-6 (Mycobacterium). The enzyme in the Archaea is homologous to the N-terminal domain of FbiB from Mycobacterium bovis, and is responsible for glutamate ligation. Therefore it seems likely that the C-terminal domain of FbiB modeled here, is involved in additional glutamate ligation. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other] |
Jiyao W et al.(2023). "The conserved domain database in 2023.",