Conserved Protein Domain Family
osq_cycl

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TIGR03463: osq_cycl 
2,3-oxidosqualene cyclase
This model identifies 2,3-oxidosqualene cyclases from Stigmatella aurantiaca which produces cycloartenol, and Gemmata obscuriglobus and Methylococcus capsulatus, which each produce the closely related sterol, lanosterol.
Statistics
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PSSM-Id: 274591
Aligned: 2 rows
Threshold Bit Score: 1141.65
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_010962068   4 LLSLQRSAGDWEGEMVWCTMILAQAVIVRTVVGRPYDARERAAIIRHFELSQLADGAWGMHPESRGYVFFTVLAYVALRL 83  Methylococcus c...
WP_013376787  23 LAATQDTEGSWYGDYGGPQFLIPIYVAGLHVMGRTPEPEQRDGLIAYLRNHQNADGGWGLDVEAPSQVFTSVLNYVALRL 102 Stigmatella aur...
WP_010962068  84 LGLGPETSMLARARAWLHAQpEGVKAVPTWGKFWLMLLGLYGREGVNAVPPELFLLPRWLPFHPSRFYCHTRLIYLGIAY 163 Methylococcus c...
WP_013376787 103 LGVGKDDAGLRRARQWFLPR-GGPLGSGAWGKIILALLGLYEYGGLQPVPPELWLLPESLPFHPSRLWCHCRMVYLPMSW 181 Stigmatella aur...
WP_010962068 164 LSGVGFSASLSdPLRDALRSELYAEPYESVDFGAFRHTVARTDLYVPISRVLRLVYDLLARYERRPWKALRQRALTLCFE 243 Methylococcus c...
WP_013376787 182 LYGRRARAPET-PLLAAIRQEIFDGGYGQVDWVAARERVSPTDVFTPRTFWLKAANQVMYGYERLAGKQLRARALDFALE 260 Stigmatella aur...
WP_010962068 244 QILREQRSTRYQGISPVSGLLNCLAIFAHDPRHPDLAPSLEGVEAWRWEDEAeGLRYVGARSNA-WDTAFAVQALAELPE 322 Methylococcus c...
WP_013376787 261 QIRAEDEATHYICIGPINKVLNMVVWHFVNPDGPEVRAHLERLPDYFYEGDD-GVRMNGYNSSElWDTAFAVQAVAATGE 339 Stigmatella aur...
WP_010962068 323 LdEEAKHALSRAHAFLDQAQMTAELADYREAWRDPALGGWCFSDGRHCWPVSDCAAEAMSALFALYERGDVriseALGAD 402 Methylococcus c...
WP_013376787 340 T-GRHRRMLEEAARFIEANQVLEDTREPQRFFRHPSKGGWPFSTRDHGWPISDCTAEGLKASLVLEPLGLN----RVPQA 414 Stigmatella aur...
WP_010962068 403 RLRLGVEFILSRQNADGGFGTYERRRGGRLLELVNPSEMFGQCMTELSYVECTASSLGALAHYLRNYPdLPGGKITAAIR 482 Methylococcus c...
WP_013376787 415 RLQDAVQLILSMQNEDGGWATYELQRGPKVLELLNPSDVFSTIMVDVSYVECTSACVQALAAWRKHHP-VPDARVDRAIS 493 Stigmatella aur...
WP_010962068 483 KAERFLRSRQLDDGSFPGFWGINYTYAVFHVAKGLRMAGVEPADPVLQAAAGWLLEKQRSDGGWGEHYSSCLEGRYVESR 562 Methylococcus c...
WP_013376787 494 RGVEFIRRTQREDGSWMGSWGVCFTYGTWFGVMGLIAAGASPDDMALRRATAFLRSYQRADGAWSEVVESCRQARWVEGK 573 Stigmatella aur...
WP_010962068 563 HSQTVMTAWALLALMEVYPAAHEAVERGIAWLCSQQGEDGGWPRQGMNGVFFGAAMLDYRLYPVYFPTWALARY 636 Methylococcus capsulatus
WP_013376787 574 QGHAVNTSWALLTLAAAGEGGSDAAQRGVRWLRERQQEDGRWPPEPIAGIFNRTCAIHYDAYLRIFPVWALAVC 647 Stigmatella aurantiaca
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