Conserved Protein Domain Family
PhnD

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TIGR03431: PhnD 
phosphonate ABC transporter, periplasmic phosphonate binding protein
This model is a subset of the broader subfamily of phosphate/phosphonate binding protein ABC transporter components, TIGR01098. In this model all members of the seed have support from genomic context for association with pathways for the metabolims of phosphonates, particularly the C-P lyase system, GenProp0232. This model includes the characterized phnD gene from E. coli. Note that this model does not identify all phnD-subfamily genes with evident phosphonate context, but all sequences above the trusted context may be inferred to bind phosphonate compounds even in the absence of such context. Furthermore, there is ample evidence to suggest that many other members of the TIGR01098 subfamily have a different primary function.
Statistics
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PSSM-Id: 132472
View PSSM: TIGR03431
Aligned: 13 rows
Threshold Bit Score: 355.51
Threshold Setting Gi: 499403202
Created: 8-Oct-2014
Updated: 2-Oct-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_002210788   1 MKKILCLT---SLLAGMMIF---------NA-TAED---Ap-----------K---EINLGILGGQNATQQIGDNMCVKE 50  Yersinia pestis
WP_008645163   1 MLRRTFLA---VVASGVVAL---------PA-FAQD---V------------K---TLNMGIISTETSSNLKSAWQPVID 49  Cupriavidus
WP_000992018   1 MNAKIIAS---LAFTSMFSLstl----ltPA-HAEE---Qe-----------K---ALNFGIISTESQQNLKPQWTPFLQ 55  Shigella flexneri
WP_011431832   1 MRRRKILF---LAAFLMGISswv----pgLA-QKQN---Wp-----------K---ELVIAEVPVESAADYEARYAPFLD 55  Synechococcus s...
WP_011369051   1 MFRRCIVG---IVAAVMLVSmvip--amaAS-APEN---Wp-----------A---KIRVGFIPTEGNADIKKRFAPLTE 57  Desulfovibrio a...
WP_011614201   1 MLRRNFLYaslLTLSFAVISc--------NQ-SISD---NqtasstnttdsrS---ELIMGLIPAESNEEMVEKFEPMRA 65  Trichodesmium e...
WP_010996386   1 MNRRLFIQ---QASLFTLTLasskilsacNS-NANDssaAl-----------K---EINFGVLSTESQDNQKPIWEPFAA 62  Nostoc sp. PCC ...
WP_011442962   1 -----------mikfstvlagalalaltasaapaQD---Wk-----------SkypELVFGKVPDENASGTTTRWTPLTE 55  Rhodopseudomona...
WP_011312812   1 ---------------------------myvkhtfsasalalvlslaaasaqaR---DIVMGLIPAENNEEMVQKFEPMRA 50  Thiobacillus de...
WP_011492416   3 FLRSLITL---AVGAAAFACv--------ATaQAED---------------------INLGIISTDSSSVLKQRWEPLIQ 50  Burkholderia xe...
WP_010975698   1 MLKKALLS---AVALFALVG---------HA-QAED---L------------K---EFRVGIIGGENEADRLRNYQCLVD 49  Sinorhizobium m...
WP_011568589   1 ------------mkktlalalaastalstGA-FAQE---I------------T---EFRIGILGGENAQDRMNSYQCLAD 49  Roseobacter den...
WP_011090669   1 ---mitrrlvlagaaalafTt--------SA-SADD---Wka--------kyS---ELTFAVIPAENASGVTERWAPFMS 54  Bradyrhizobium ...
WP_002210788  51 FLDKELNV-KTNLHNASDYSGVIQGVLGGKIDLVLsMSPSSFASIYiKDPNAv-ELVGIAIDdTDKSRGYH-SVVVVKAD 127 Yersinia pestis
WP_008645163  50 DLSRALGV-QVKPFFASDYAGIIEGMRFNKVQIAW-YGNKSAMEAV-DRANG--EVFASVID-KDGNPGYW-SLLIARKD 122 Cupriavidus
WP_000992018  56 DMEKKLGV-KVNAFFAPDYAGIIQGMRFNKVDIAW-YGNLSAMEAV-DRANG--QVFAQTVA-ADGSPGYW-SVLIVNKD 128 Shigella flexneri
WP_011431832  56 YLKQKLGI-PVRLFVAGDYTAVMVSQAQGQTHVAF-YGPGSYVDAI-EKANApiEAFVKEDS-LRSGTVYH-SLILSKKG 130 Synechococcus s...
WP_011369051  58 HLRNILGI-EVEAFSASDYAGIITAMAHQHIDFAY-FGPKSYVEAS-EKAGA--QALVMELN-KEKQPGYT-GIIIVRKD 130 Desulfovibrio a...
WP_011614201  66 YMEKKLNR-PIKVFTATDYAGVIEAMRQDKVDIAW-FGPLSYVLAE-QEAGA--EAFATGVR-TKTGKSTYkSILVVPGD 139 Trichodesmium e...
WP_010996386  63 AMSQEVGI-PIKPFYVTQYAAVIEAMRFGKVQAAW-LGGKSYIEAA-RVANA--EAFAQVVS-ADGTRGYY-SHLIANKD 135 Nostoc sp. PCC ...
WP_011442962  56 YLSKKLGT-KVTLRIANDYAAVIEGQRSGNIQIAM-YGPASYARAYlIGAKV--EPFAIEVN-NDGSKGYY-SVLYVKTE 129 Rhodopseudomona...
WP_011312812  51 HLEKKLGQ-KVKVYTATDYAGVIEGMKKKRVDVAW-FGPLSYYLAE-QEAGA--EAFAVGIR-EGGTTHTYkSLFVAPCD 124 Thiobacillus de...
WP_011492416  51 DMNRQTGL-NVKAFFATDYAGIIEGMRFNKVQVGY-FGNASAIEAV-DRSQG--EVFAKVQY-ANGDAGYY-SVLITNVN 123 Burkholderia xe...
WP_010975698  50 QLPAAIGVeKVSLFPAADYDGVIQGLLGGTLDYAE-LGASGYAKIYlAKADAv-EPILTTVQ-TDGSTGYH-SIMVARKD 125 Sinorhizobium m...
WP_011568589  50 YTTEALGV-ETKLFAPADYNGVIQGLLGGTIDMAW-LGASAYAATYlQDPEAv-KPVLIKVN-VDGSIGYH-SIGFARVD 124 Roseobacter den...
WP_011090669  55 YLSKELGV-KVTLRIANDYAAVIEGQRAGNIHIAS-YGSASFARARlTGVKT--DAFANDIN-ADGSTGYY-SVFFVKAS 128 Bradyrhizobium ...
WP_002210788 128 SPYQK-----------LEDL----KGKAFGFADPDSTSGFLIPNQSFKQQFGGSVDnkynNFFSSVTFSgGHEQDILGVI 192 Yersinia pestis
WP_008645163 123 SDLKS-----------VEDVikrgKDLTYGAGDPNSTSGTAVPGYYLWAANKVDPK----TLFKAVRIS-NHETNLLSVL 186 Cupriavidus
WP_000992018 129 SPINN-----------LNDLlakrKDLTFGNGDPNSTSGFLVPGYYVFAKNNISAS----D-FKRTVNAg-HETNALAVA 191 Shigella flexneri
WP_011431832 131 SGIKT-----------LEDA----KGKDFAFVDPESTSGFKVPMAYFCLEAKIKPK----EYFKRVAFAgTHESVILGIA 191 Synechococcus s...
WP_011369051 131 SDMMQ-----------LDDI----KGRVFAFTDPNSTSGYLVPNVLFARDLKMKPE----DYFKQVKFSgSHGASILAVK 191 Desulfovibrio a...
WP_011614201 140 STVQS-----------IQDL----KGKNVAFVDPASTSGGLVPSYLVLKATGQKPK----DFFGKLTYAgSHDAAGMAVK 200 Trichodesmium e...
WP_010996386 136 NPITAeakavggdkyvIQNA----AKLTFAFNEPNSTSGFLVPSYYIFTKNNIEPK----KAFKRLIFAgNHEACALAVA 207 Nostoc sp. PCC ...
WP_011442962 130 SPYKN-----------IQDL----KGKNLCLVDPNSTSGNNVPRFEM-NKLSIDPD----KFFGKVIYAgSHENAVIGVA 189 Rhodopseudomona...
WP_011312812 125 AGVKS-----------IKDL----KGKSVAFVDPASTSGGLMPTYMVKKETGMMPQ----QFFGKFTYSgSHDAAELAVK 185 Thiobacillus de...
WP_011492416 124 SRFKT-----------LDDVfrntKDVTLGFGDPNSTSGTLIPGYYLFAKHNTPVN----TSFKAVLPS-SHEANLLAVV 187 Burkholderia xe...
WP_010975698 126 SGITK-----------LEDL----KGKKLGFADPDSTSGYLVPLVTLPEAIGAPVK----EYFGETGFGgGHENLVLEVV 186 Sinorhizobium m...
WP_011568589 125 SGITS-----------LDDM----KGKVFGFGDPNSTSGYLIPSIEIPQYKDGMTMes-gEYFGEVKFTgGHEQTIVAVN 188 Roseobacter den...
WP_011090669 129 SPYKS-----------IDQL----KGKNLGLVDPNSTSGNNVPRFELDKMGIADAD----TYFSKVVFTgSHENAILALA 189 Bradyrhizobium ...
WP_002210788 193 NGQFAGAvtwasMI-----GDYdtgytsgAFTRMIRMGQ-------PDLMKKIRIIWQSPLIPNGPILVRSALPPEFKAQ 260 Yersinia pestis
WP_008645163 187 NKQVDVA-----VN-----NTE-------NFERYRINTG-------KNAYDDVRVLWKSPLIPADPLVYRKDLPPELKKK 242 Cupriavidus
WP_000992018 192 NKQVDVA-----TN-----NTE-------NLDKLKT-SA-------PEKLKELKVIWKSPLILGDPIVWRKNLSETTKDK 246 Shigella flexneri
WP_011431832 192 QGTIPVG-----VT-----WDT-------GISIATNKGQ-------IKGIEDLEVIWRSDPIPSSPWAYRKDLPEDLKEA 247 Synechococcus s...
WP_011369051 192 NKAIEAA-----AT-----NNI-------DLDRMIEKGQ-------VAA-DDFRILWRSELIPGAPMAARRDLPQSLKAA 246 Desulfovibrio a...
WP_011614201 201 NQTVDAA-----GT-----NDI-------TYNKMINKGL-------ISE-ESNRILLESEPIPGSPLAYRQELDEQTKNN 255 Trichodesmium e...
WP_010996386 208 NKQVDVA-----TV-----SNE-------ALSRLER-TN-------PTARQKIEIIWQSPLIPSDPIVYRQDLPADIKNR 262 Nostoc sp. PCC ...
WP_011442962 190 QGTCDAAfnwwnTE-----AES-------NLLRMDRKGM-------AKA-ADFRIILKSDQIVNSPMAYLTDLPADLKAA 249 Rhodopseudomona...
WP_011312812 186 NKTVDAA-----AD-----NDI-------TYEKMLAKGL-------ITK-ETNCVVKESDPLPGSPLVYRKDLPAATKKK 240 Thiobacillus de...
WP_011492416 188 NNKIDIA-----TN-----NTE-------MLDTLK-KEH-------PDKFAQVRVLWKSPLIPSDPLVWRKDLPQATKDK 242 Burkholderia xe...
WP_010975698 187 KGTFDAG-----TTfgsgvGEFkdgytsgNLRKMVDKGI-------VDM-NDLVELWKSPLIPNGPIVVRTALNDDMKAK 253 Sinorhizobium m...
WP_011568589 189 NGDIDGGvtwadGQ-----GNWedgynsgALRKAVDAGL-------VDM-NDMVQIWKSNVIPEGPVVLRKALPAQVRET 255 Roseobacter den...
WP_011090669 190 QGTVDVA-----ANqwtsdDDS-------TLAQMLTKGMlknadgsPMKKDDFRIIHKSAPIINGPYAYNSDLPEEAKAA 257 Bradyrhizobium ...
WP_002210788 261 LVAAIKKLDKEDHGCFIKAMGGK---QHIGETSLSEYQNIIDMKRELTK 306 Yersinia pestis
WP_008645163 243 IQDFFVNYGKGADAAREKQALATltyQGFRVSTDAQLVPIRQIELAKEK 291 Cupriavidus
WP_000992018 247 IYDFFMNYGKTPEEKAVLERLGW---APFRASSDLQLVPIRQLALFKEI 292 Shigella flexneri
WP_011431832 248 LRTAYLEYENTPEGQKWLEARGl---KGFEPASDADYDPFRKVNDALKK 293 Synechococcus sp. JA-2-3B'a(2-13)
WP_011369051 247 FTGAML-MFNADKAGLEKLQNG-----GYQYTDDSTYDIIRYLKRLKNE 289 Desulfovibrio alaskensis
WP_011614201 256 IRETVLNAHKDIKVT----GYGDl--LNYESATPKDYGVVRDMINTLGI 298 Trichodesmium erythraeum
WP_010996386 263 LQKFFYNYKDAKVLTPFEI-------SGFVQAEDKNWHTIRELEIAKKI 304 Nostoc sp. PCC 7120
WP_011442962 250 IRKAVLDLATDDPETFNKIYEGKg--KPYDAVDHKAYQPVIDLTKFVDT 296 Rhodopseudomonas palustris
WP_011312812 241 IRDAILNAHKEIKVS----GYGNl--SHYVAVAPKDYQMIRDMVKDLGl 283 Thiobacillus denitrificans
WP_011492416 243 LRNFFLNYAKTDPHEKAVMAAITg-yGGFAASSDTQLLPIRQVALFQQK 290 Burkholderia xenovorans
WP_010975698 254 FKQFMMDLPKTDAACFSAIQGGDf--TGFVEVNSDFYKPIIDARKATIG 300 Sinorhizobium meliloti
WP_011568589 256 MTALVDGLHERDPDCAYGVAAGDt--LGFQPVTHDTYISIVEARKAKIG 302 Roseobacter denitrificans
WP_011090669 258 IAKAFFDAPAKDKAAFDRLQDGQk--KGFHPATTKDWDGTIELIKFVDa 304 Bradyrhizobium diazoefficiens
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