Malonate decarboxylase can be a soluble enzyme, or a sodium ion-translocating with additional membrane-bound components. Members of this protein family are integral membrane proteins required to couple decarboxylation to sodium ion export. This family belongs to a broader family, TIGR01109 of sodium ion-translocating decarboxylase beta subunits. [Transport and binding proteins, Cations and iron carrying compounds]
Jiyao W et al.(2023). "The conserved domain database in 2023.",