Conserved Protein Domain Family
citrate_citX

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TIGR03124: citrate_citX 
holo-ACP synthase CitX
Members of this protein family are the CitX protein, or CitX domain of the CitXG bifunctional protein, of the citrate lyase system. CitX transfers the prosthetic group 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA to the citrate lyase gamma chain, an acyl carrier protein. This enzyme may be designated holo-ACP synthase, holo-citrate lyase synthase, or apo-citrate lyase phosphoribosyl-dephospho-CoA transferase. In a few genera, including Haemophilus, this protein occurs as a fusion protein with CitG (2.7.8.25), an enzyme involved in prosthetic group biosynthesis. This CitX family is easily separated from the holo-ACP synthases of other enzyme systems. [Energy metabolism, Fermentation, Protein fate, Protein modification and repair]
Statistics
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PSSM-Id: 163145
View PSSM: TIGR03124
Aligned: 18 rows
Threshold Bit Score: 194.013
Threshold Setting Gi: 488755911
Created: 8-Oct-2014
Updated: 2-Oct-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_020750227  41 IQLSDMLRAREERALRQLHLLKEYP-EgSLLSVTMNIPGPIKTSPKLLEAFDIVIKAIQTALADD--KICYQLRLLPTTG 117 Streptococcus p...
WP_000550422  13 VSIPELLVSRDERQARQHVWLKRHP-V-PLVSFTVVAPGPIKDSEVTRRIFNHGVTALRALAAKQgwQIQEQAALVSASG 90  Enterobacteriaceae
WP_011254390  10 QDIAQVLNAKDYRVALQKAIFNKYPdQ-TLVDINLNIPGPIKNNQYLKNIFDKGISELENSWQKSgyKYKLVKALNEDSG 88  Lactobacillus a...
WP_010945129  16 VSLEQLLIAREQRVALQQQCLHEYQ-Q-TLLSLTLTAVGPVKKNALLDYVFAKALANITACFNKLsvTATAQFIRPLQTG 93  Haemophilus duc...
WP_005693884  15 ISLEALLNAREERAILQQQLITQYG-Q-TLLCITLTAVGGVKKNALLDYVFTKALENLTALFTQLniTAVKEIIRPLETG 92  Haemophilus inf...
WP_002379280  11 VTLLEMLDAREQRAATQKELLETAP-EaSLLSATMNIPGEVKNSPTLTAVFLEVIDEVEQQLLDQ--VPIVNFYRNEKTG 87  Enterococcus fa...
WP_011016309   6 VGIDEVLNCREKRVAIQNEMIRKYK-K-PVISFTMNIPGPIKTNNEIKKAFDIGKVLILEKLKENniEILEIQELNENTG 83  Fusobacterium n...
WP_011010286   6 kFLIEILKGREERAFEIKKLNEKFH-G-TIICLTLNIPGPDKLDELYYYAFNEATKALEASL-----NINVLKERAPLSG 78  Clostridium per...
WP_013355357  14 QTITAMLAARDQRVAYQQQLTATNP-RaTIAAIKLNIPGPIKNNAALRRLFLAGVQRFEAELS----TYTVAADWNHPAG 88  Lactobacillus p...
WP_011374920  12 IDLGQMLTAREQRVVNQTRLLKKYP-EaTLLCGTMRIPGPIKTGPKLKGLVQQFCETIQKQYKDK--LVDQLIKLEAITG 88  Lactobacillus s...
WP_020750227 118 YEYYLITSLPSRDLKLKMIALETELPIGRLMDLDVLVLQ-NdlpHSI---SRTVLGGSPRQCFICSKEAKVCGRLRKHSV 193 Streptococcus p...
WP_000550422  91 PEGMLSIAAPARDLKLATIELEHSHPLGRLWDIDVLTPE-G---EIL---SRRDYSLPPRRCLLCEQSAAVCARGKTHQL 163 Enterobacteriaceae
WP_011254390  89 CEKFYVLSLPAIQVKRSTIDFEDYTPLGRLFDADVLVKDhN---TAI---SRKDLGQNVRKCFLCSRRAKECARSRRHSV 162 Lactobacillus a...
WP_010945129  94 HEALFVLPIDAKILKRAMIELENSSPLARLWDIDVISQE-G---H-Y---SRGEFGFAERTCLMCAESAKICARSRRHSI 165 Haemophilus duc...
WP_005693884  93 HEAYFVLPIDARTLKVLMIELEESIPLARLWDLDVFNAK-G---NLL---SRTDFDLSPRTCLVCGENAKICARTHKHEI 165 Haemophilus inf...
WP_002379280  88 PEYYLAVSLAPQELKQRMVKIEETHPYGRLVDLDVLWGN-Ee-lKSL---HRGDLGLPPRRCFICQEVAKVCGRNRRHSL 162 Enterococcus fa...
WP_011016309  84 NELFISTNSLAKKIKNITVAIEEGYDLGRLFDIDVIDIN-F---EKL---SRKSF----RKCLICEEQAQECGRSRKHSV 152 Fusobacterium n...
WP_011010286  79 YEAYFVSDKDIKEIKRLALTLEKEHPLGRLFDIDIFYKD-L---SKI---SREDLGEPKRKCFLCGEEAVSCGRSRKHSV 151 Clostridium per...
WP_013355357  89 NERFLILTTDFATSKRLAVAFEEHDPLGRLYDIDILQAG-Sq--RAL---SRTDLGLPKRRCLLCHREAKDCARSRRHSV 162 Lactobacillus p...
WP_011374920  89 PEFYFVLNIAPKQIKQEMVCFEQGNPLGAIWDLDVLYWE-S---EQLvqvSRVALGAPRRTCLVCGQDAKNCSRSRQHGL 164 Lactobacillus s...
WP_020750227 194 EEMQTAISKLLHSF 207 Streptococcus pyogenes
WP_000550422 164 TDLLNRMEALLNDv 177 Enterobacteriaceae
WP_011254390 163 KEMQDFISNLYIKY 176 Lactobacillus acidophilus
WP_010945129 166 DDLLSEIHTRAQQY 179 Haemophilus ducreyi
WP_005693884 166 DEIVDKIQSLAQNH 179 Haemophilus influenzae
WP_002379280 163 EAMQEKITEIILtr 176 Enterococcus faecalis
WP_011016309 153 EELQNKIEEILKKs 166 Fusobacterium nucleatum
WP_011010286 152 YELTSSIKEKILKY 165 Clostridium perfringens
WP_013355357 163 AELQQKIAAMYMKe 176 Lactobacillus plantarum
WP_011374920 165 LEVQLKIEQIIEEg 178 Lactobacillus sakei
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