Conserved Protein Domain Family
couple_hipB
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TIGR03070: couple_hipB 
transcriptional regulator, y4mF family
Members of this family belong to a clade of helix-turn-helix DNA-binding proteins, among the larger family pfam01381 (HTH_3; Helix-turn-helix). Members are similar in sequence to the HipB protein of E. coli. Genes for members of the seed alignment for this protein family were found to be closely linked to genes encoding proteins related to HipA. The HibBA operon appears to have some features in common with toxin-antitoxin post-segregational killing systems. [Regulatory functions, DNA interactions]
Links
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Statistics
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PSSM-Id: 213767
Aligned: 13 rows
Threshold Bit Score: 68.4548
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
WP_010920580 222 RALGQLVRQARERMGLTQAAFADAAGVGRRFVSELENGKPTLELGKVMAVCAAAGLDL 279 Caulobacter vibrioides
WP_012753632   7 RDIGMLIRAKRSERSWTQGDLARHVGTTQRWISEVENGKATAEIGMVLQTLSMLGIRL 64  Methylobacterium extorquens
WP_011897107  72 EEIGMALLNGRKELGLRQGELADLAGVSERFIRDVEKGKTTVRLDKVIDVLRVLGLEL 129 Corynebacterium glutamicum
WP_026006841   8 SDIGNIIRARRKRLGWDQARLAHEIGVSRQWIVDIEKGKPRAELQLILRALQALGLEL 65  Xanthomonas axonopodis
WP_011216257   4 HEIANLVHYYRKHSGLSQQELARLAGVGKTVIYDIEKGKESVRLNTLLKVLDVLNIQM 61  Legionella pneumophila
WP_021678693   6 TIIAQYVKEMRKKYKLTQVDLSEKAGVGLRFVRELEQGKTTLRLDKVNKVFELFGSEC 63  Porphyromonas gingivalis
WP_014708734   4 TKLSITVKALRKEYGLTQEDLAMKSGVGLCFVRSLEQGKASLRMDKVNQLLDLFNYEL 61  Prevotella intermedia
WP_011111889   9 EQLGDALRAARKQLGLTQPQLALAAGVGVRFIVDLEAGKPTLRLENVLRVIDALGGAL 66  Nitrosomonas europaea
WP_003016100   9 KDLGLLIRKARKKQGLTQADLSGISGLGTRFIGEVENGKNTAHIGKVIQLASSLGLVI 66  Francisella tularensis
WP_008769436  21 KQIGIQIRQRRKMLGINQQTLADLAQISINTITKIENGEININFQKLYAILEVLGLEL 78  Bacteroides
WP_016725279   9 PQLSAHLKSLRKARGLTQAQLGALLGVSQNRIADIEKDPGAVGFEQLLRILHALGAQL 66  Ralstonia solanacearum
WP_011211859  18 lEFGSFLVDRRIALGLTQLDVAELADVGLSSVRALEGGHDSPTLAVTLRVLDALGLTL 75  Nocardia farcinica
WP_011693796   7 DMLAAEVRARRAALQLTQHDLAHLAGVSERFVRFVEQGKRSVQLDSLLALLETLGLEL 64  Arthrobacter sp. FB24
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