Conserved Protein Domain Family
restrict_Alw26I

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TIGR02986: restrict_Alw26I 
type II restriction endonuclease, Alw26I/Eco31I/Esp3I family
Members of this family are type II restriction endonucleases of the Alw26I/Eco31I/Esp3I family. Characterized specificities of three members are GGTCTC, CGTCTC, and the shared subsequence GTCTC. [DNA metabolism, Restriction/modification]
Statistics
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PSSM-Id: 132031
Aligned: 6 rows
Threshold Bit Score: 614.129
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
AAM09638  39 DAAFLEYTRLIVNHPNYFGMPDPFGEKGEIQWEAPSNRASGkFKHTHQRRYEWWKNKARSIGIDp-DTEKAWISKTAKLI 117 Escherichia coli
AAS09914  12 HQNYIDYMHFIVNHKNYSGMPNAIGEDGRINWQVSSGKTTS-FYEYYQARFEWWEKKADELNLPgtGNSNKRFSLAARLI 90  Geobacillus stearot...
AAM09641  14 NPKYIAYMRMIVTHPNYAGMPNAVSQDGRINWQVSSGKTTS-FYTYYLERRAWWIAKADSLGLPgkSDENDRFTIAARII 92  Hafnia alvei
AAR96018  11 HPIFLEYAEQIIQHKEYQGMPDLRYPDGRIQWEAPSNRKSGiFKDTNIKRRKWWEQKAISIGID--PSSNQWISKTAKLI 88  Geobacillus stearot...
AAQ72363   9 HPKFIEYMDFIIQHPNYKGLPITKKSDGSWSWFGTKKTQIG------KARIAWCENKAKELGFP---IEPGVYANVMREI 79  Geobacillus stearot...
AAM09643   9 SPEFQQYQKTIIEHPNYIGLEYAG------SWVKAGKSPVG------QNRKKWADQKIAELGIT----GSGIYAKLMYTI 72  Acinetobacter lwoffii
AAM09638 118 HPLGVKPCKKCGKEMELSYSYPNEHFFSRVRKlNYI-DETFELSQNEHIVDLLTRLDDRFGERIYLDLPHLFSTKSI-TI 195 Escherichia coli
AAS09914  91 HPTGQRPCRLCGKYQYVGYMYVSHNLYKRWSKiTGReDLFFKKQNIIEAANIFKSIMGEQALINELTTIFPERKDYFnRL 170 Geobacillus stearot...
AAM09641  93 HPTGYRTCRLCGEDFNVGYFYLNHAFCVKLKN-DFPqLDVSKEQPIDDVIEQLRQLVSEDTIEAYFLECFPERASFFtRF 171 Hafnia alvei
AAR96018  89 HPTMRKPCKKCGRIMDLRYSYPTKNLIKRIRKlPYV-DESFEIDSLEHILKLIKRLVLQYGDKVYDDLPKLLTCKAVkNI 167 Geobacillus stearot...
AAQ72363  80 HPTKWKVCQTCGHSMSIYYHYPSANFLKALKK-EFG-VEYTEVDHIADIWDDLLSRGFSNNKIASFLIKKGELDLNAkTS 157 Geobacillus stearot...
AAM09643  73 HPFKVKPCQTCGQTMSLDYVYPNKNFANKLTK-TFP-ILTGKDLLTTSIYDILKVLNSDNNQELVFLLRSTLKRKDIeNL 150 Acinetobacter lwoffii
AAM09638 196 PdissNLEAwiEYLKEQYIPQESRMLSPGAMANPPDRFDGFHSFNRCCRSIADKGRTKENLKSYVTDRRVFEYWVDGDWV 275 Escherichia coli
AAS09914 171 P----NIED--FFVSSSHIKNNGNYISPGFMANPPDRLDGFHDYGICCRKEKDPGRHDDNMRLYNHDRRAFMWWSEGDWA 244 Geobacillus stearot...
AAM09641 172 GvtkqAFEQ--SCYLRTYK------LSPGFMGNPPDRLDGFHDYHGSCRKNNDPGRFDENMRSYSHDRRSFEWWAEGNWA 243 Hafnia alvei
AAR96018 168 PrlgnDLDTwlNWIDSVYIPSEPSMLSPGAMANPPDRLDGFHSLNECCRSHADRGRWEKNLRSYTTDRRAFEYWVDGDWV 247 Geobacillus stearot...
AAQ72363 158 -----SKDEviYELESVCRNKGKKILSPGAMSNFPDRFDGFHTYNRCCRASQDKGRSKENLKSYTKDRRAYEYWSDGNIH 232 Geobacillus stearot...
AAM09643 151 -----DVQElvQCLIEESRSGLIKVLGPGAMSNFPDRFDGFHSYNRCCRSTEDTGRSVENLKSYTKDRRAYEAWSDGNHR 225 Acinetobacter lwoffii
AAM09638 276 AADRLMGQVRTNNIFINEECLnagngglHPTPCQADHIGPISLGFSHRPQF-QLLCKSCNSAKNNRMYLSDIISLLEAEN 354 Escherichia coli
AAS09914 245 LADALYNKAGAGKCADPDCQK-------EVEKISPDHVGPISCGFKQIPFF-KPLCASCNSAKNRRFSYQDVKELLKYEN 316 Geobacillus stearot...
AAM09641 244 LADALYNKAGPGRCSIPNCGK-------MLEKISPDHIGPLACGFKQLPLF-APTCQNHNSAKNRRFTLNDVKILLNYET 315 Hafnia alvei
AAR96018 248 AADKLMGLIRTNEQIKKETCLnd----nHPGPCSADHIGPISLGFVHRPEF-QLLCNSCNSAKNNRMTFSDVQHLINAEN 322 Geobacillus stearot...
AAQ72363 233 AANQFMGSPFFNN-------------------ISADHIGPISLGFVHDPRYlQPMSGGDNSSKRDRLQLDDIEKIIETEK 293 Geobacillus stearot...
AAM09643 226 AANQLMGDQVFSR-----------------TGLSADHLGPISLGFVHDPRFmKAMTSGENSSKRDRLILSDLVTMIDIES 288 Acinetobacter lwoffii
AAM09638 355 -EGHTVISWFAEEVWNRLKHSV------DDSEKAL--RLSKILRDNRHTYMNLLKKIM----DEGYYTFLASLLHLEV-- 419 Escherichia coli
AAS09914 317 yTGDSVASWQVRALWDNCKHLV------KNDDDSK--LLSNLMRSLQDYYLRSLYKLF----SNGFAHLLSYFLTPEY-- 382 Geobacillus stearot...
AAM09641 316 vTAESVASWQIRAHWDKYKNIV------SDDYQTK--AFSNSLRSLQDMYLRILWELY----LNGNARFLATILKPEY-- 381 Hafnia alvei
AAR96018 323 -NGEEVASWYCKHIWDLRKHDV------KNNENAL--RLSKILRDNRHTAMFILSELL----KDNHYLFLSTFLGLQY-- 387 Geobacillus stearot...
AAQ72363 294 rTNVYPMSWYSKLIWEYIKKNY------STHKSLIsgVYRDALKQNMSNFMYILWYILehcnQDGEHFLEEALLKPNYdy 367 Geobacillus stearot...
AAM09643 289 rENINASSWFCSIIWQSIKNDIqngkitSNNDTLR--EYQTTLKKNKDLFFNILGYIAs---SKNGQEFLIWYLKDRYk- 362 Acinetobacter lwoffii
AAM09638 420 ANYNPIFE---GLCISNhlTHYKSLKKIKRE-SKYAAVQKTRRIRIAFTSLNDYHRKENRN 476 Escherichia coli
AAS09914 383 AHYKITFE---GLNTST--LEYERYYKTFKK-TKSTSSLAARIVRIAFEELEIYNSKDINE 437 Geobacillus stearothermophilus
AAM09641 382 ALEQYHFE---NLDIGT--LQFTGVYSDKKI-TNSRKSLAARTVRIAFEALTEYVSKPIER 436 Hafnia alvei
AAR96018 388 AERSVSFS---NIKIENhiITGQ-ISEQPRD-TKYTEEQKARRMRIGFEALKSYIEKENRN 443 Geobacillus stearothermophilus
AAQ72363 368 FQYSYTFN---EL--------GEIVSINPRHfTDRNQYETERYKRIAFESVYDYNEKENRN 417 Geobacillus stearothermophilus
AAM09643 363 FEDNYLYDyvlDTDIGSn-TFGQIKSKTPRNlTARADGEEDRAIRIGLESIKDYASKNNRK 422 Acinetobacter lwoffii
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