Conserved Protein Domain Family
acyl_WS_DGAT
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TIGR02946: acyl_WS_DGAT 
acyltransferase, WS/DGAT/MGAT
This bacteria-specific protein family includes a characterized, homodimeric, broad specificity acyltransferase from Acinetobacter sp. strain ADP1, active as wax ester synthase, as acyl coenzyme A:diacylglycerol acyltransferase, and as acyl-CoA:monoacylglycerol acyltransferase. [Unknown function, Enzymes of unknown specificity]
Links
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Statistics
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PSSM-Id: 274360
Aligned: 25 rows
Threshold Bit Score: 363.549
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
CAI48224       7 LSGADNAWRRMGTPTNL--MTITGVMMFDer------mTYEDLCNRLEERLLRFERFQQRIGGR---------KRRFRQP 69  Natronomonas ph...
AAK47554       4 LTTLDAGFLKAEDVDRHvsLAIGALAVIEgp-----apDQEAFLSSLAQRLRPCTRFGQRLRLR---------PFDLGAP 69  Mycobacterium t...
AAK47818       4 LTALDAGFLKSRDPERHpgLAIGAVAVVNga-----apSYDQLKTVLTERIKSIPRCTQVLATE---------------- 62  Mycobacterium t...
BAD56419       4 LTGLDASFLYLETGTQH--LHVCALLILDptae-gadySFDAFKAELGRRLAYVPQMRRRLRQV---------PLNLDHP 71  Nocardia farcin...
BAD59451       5 LTPQDAAFYRLESSSNP--IHIGSLAILAspes-gddlDYDRLVDLVESRLPLVPRYRRKVREV---------PLALGRP 72  Nocardia farcin...
CAD95354       5 LSASDASFYQLENTATP--MYVGLLLILRrpr---aglSYEALLETVEQRLPQIPRYRQKVQEV---------KLGLARP 70  Mycobacterium b...
CAB61924       6 LAPLDLAFWNIESAEHP--MHLGALGVFEadsptagalAADLLA----ARAPAVPGLRMRIRDTwqppmalrrPFAFGGA 79  Streptomyces co...
WP_011399653   4 LSELDASFLYLETESAP--MHIGGVYILDsseq-sgelSFEAFRQHIESRLPAARQFRQRLVEV---------PLKLGHP 71  Hahella chejuensis
WP_011395041   9 VSGVDSAWLRLDRPTNL--MVITAMAVVEp-------iPFNKLKELINSRFLAFPRFRQKPVNH------------SGFY 67  Hahella chejuensis
WP_011395160   8 MSAVDTAWLRMERPANL--MMICIVLVMEsp------vHANALKQLFTARLLPLPRFRQTVHKT------------EHGY 67  Hahella chejuensis

CAI48224      70 YWETVDGFDVEPHVYHISLPEPQDKATFEAFVGKLMSRPLDESRPLWEAYLVDGAgPG------EGNAVAFRLNHSIGDG 143 Natronomonas ph...
AAK47554      70 KWVDDPDFDLGRHVWRIALPRPGNEDQLFELIADLMARRLDRGRPLWEVWVIEGL-AD------SKWAILTKLHHCMADG 142 Mycobacterium t...
AAK47818      63 -WIDYPGFDLTQHVRRVALPRPGDEAELFRAIALALERPLDPDRPLWECWIIEGL-NG------NRWAILIKIHHCMAGA 134 Mycobacterium t...
BAD56419      72 LWVEDADFDLDYHIRRYGLPRPGGRKELADLVGDIASTPMDRSRPLWQMSVVEGV-DG------DKVAVISKYHHAAVDG 144 Nocardia farcin...
BAD59451      73 VWVEDSRFDITYHIRRSALPSPGTEEQLHELVARLASRPLDQSRPLWEMYLIEGL-AG------GRSAIFTKSHSALVDG 145 Nocardia farcin...
CAD95354      71 VWIDDRDFDITYHVRRSALPSPGSDEQLHELIARLAARPLDKSRPLWEMYLVEGL-EK------NRIALYTKSHQALING 143 Mycobacterium b...
CAB61924      80 TREPDPRFDPLDHVR---LHAPAT--DFHARAGRLMERPLERGRPPWEAHVLPGA-DG------GSFAVLFKFHHALADG 147 Streptomyces co...
WP_011399653  72 YWVDDPDFDISNHLRHAHLPSPGAEAQLLQLTSAILAEPLNRERPLWEITLVDGY-QQsdtrepGCRALIVKIHHSVING 150 Hahella chejuensis
WP_011395041  68 FWEEDPYFSLDYHVRKVALPQPADKGALEKFIGELMSTPLDPGKPLWQVYLIENY--G------DHHVCVMRVHHCYADG 139 Hahella chejuensis
WP_011395160  68 FWRDDTNFNIDNHVHLVGLPGAGNQQDLQNFASDISSTPLDFSKPLWQVHLIDRY--K------SGSAMIIRVHHCIADG 139 Hahella chejuensis

CAI48224     144 FALLYVLLGLVDNPGDielPSGMVSApddigddadsgaDGGNG----SDESDVASG--DGQPAdtdSKSDGERGSSGLPS 217 Natronomonas ph...
AAK47554     143 IAATHLLAGLSDESMS---DSFASNI------------HTTMQ----SQSASVRRG--GFRVN---PSEALTASTAVMAG 198 Mycobacterium t...
AAK47818     135 MSAAHLLARLCDDADG---SAFANNV------------DIKQI----PPYGDARSW----------AETLWRMSVSIAGA 185 Mycobacterium t...
BAD56419     145 ITGANMMMHLCDFEPG---ATRTEAPeppda---hrppRPEPQ----PSDWRLLAD--AAVRL---PA-RA-GVVGMLPK 207 Nocardia farcin...
BAD59451     146 DEALEIGHVILDTSPS---PRELADFa----------wEPPRE----PTDMELLLG--ALSRLaakPREAVTVVRESSAQ 206 Nocardia farcin...
CAD95354     144 VTALAIGHVIADRTRR---PPAFPEDi----------wVPERD----PGTTRLLLR--AVGDWlvrPGAQLQAVGSAVAG 204 Mycobacterium b...
CAB61924     148 LRALTLAAGVLD-------PMDLPAP------------RPRPE----QPPRGLLPD--------------VRALPDRLRG 190 Streptomyces co...
WP_011399653 151 ATGEELMSALLDFSPE---PSKRPLPqq--------awNPNPL----PSKARLIGN--VYGSAlntPFRLANMAKDAAAS 213 Hahella chejuensis
WP_011395041 140 LALVAVFGSLSDQSPN---INPFPLD------------PGKQRdagvRARQSFVMGmeTLSRAvekCTKLRYRIAEEGKS 204 Hahella chejuensis
WP_011395160 140 IALTRVLLSLADQNHE---RSPPPNA------------SLPTK----PASWSGIAA--KAMHI---GQEIIEEGMSLARH 195 Hahella chejuensis

CAI48224     218 PVSAAGTAATgva-------tgyDLLFGDDDPDTSLRGELgQ-TKRAAWTDEIPLEQVRTVceAQPH-RATINDVLLAAL 288 Natronomonas ph...
AAK47554     199 IVRAAKGASE-------------IAAGVLSPAASSLNGPI-S-DLRRYSAAKVPLADVEQV--CRKF-DVTINDVALAAI 260 Mycobacterium t...
AAK47818     186 VCTAAARAVS---------------WPAVTSPAGPV-----T-TRRRYQAVRVPRDAVDAV--CHKF-GVTANDVALAAI 241 Mycobacterium t...
BAD56419     208 TVGMLAGFVMrrrat----dmpgM-AIPLTAPRTPFNKAI-T-PHRTVAFTATDLDTVKEI--KEAF-AVKVNDVVLAAV 277 Nocardia farcin...
BAD59451     207 AFAMVGAAGRavds-----vvsaVRSVAAGAPHSPLNAPT-S-RHRRFDVARTDLADHRSI--RKRF-DCSINDVILAVV 276 Nocardia farcin...
CAD95354     205 LVTNSGQLVEtgrkv----ldiaRTVARGTAPSSPLNATV-S-RNRRFTVARASLDDYRTV--RARY-DCDVHDVVLTVI 275 Mycobacterium b...
CAB61924     191 ALSDAGRALDig---------aaAALSTLDVRSSPALTAAsS-GTRRTAGVSVDLDDVHHV--RKTT-GGTVNDVLIAVV 257 Streptomyces co...
WP_011399653 214 AFYTLLVQRLhr---------laLPPALFSAPPTSFNRAI-G-KERSLGYFACDLDRLKQL--KKHHeDITLNDVVMTLC 280 Hahella chejuensis
WP_011395041 205 ILREPGYAVEgvrqglngaaeiaRLAALEADDPTPLRGEL-GvMKCCTWSELIPLHKFKEV--ALAF-GCSINDVLLSCV 280 Hahella chejuensis
WP_011395160 196 PEQILEIARQgvamg----sevaRVAALPADPATCFKGAL-SgRKRLAWAQPLDFLQVKQT--AKAL-KATINDVLLCAA 267 Hahella chejuensis

CAI48224     289 AGALRRLLEDRG-Ep-VDGMELHGTVPVNLKPma----eRD------GSLGNNFGLVFLPLPVGTEPLQERISIIHEWMD 356 Natronomonas ph...
AAK47554     261 TESYRNVFIQRG-Er-PRFDSLRTLVPVSTRSn-----sAL------SKTDNRVSLMLPNLPVDQENPLQRLRIVHSRLT 327 Mycobacterium t...
AAK47818     242 TEGFRTVLLHRG-Qq-PRADSLRTL-----------------------EKTDGSSAMLPYLPVEYDDPVRRLRTVHNRSQ 296 Mycobacterium t...
BAD56419     278 GGTLRRYLERRG-E--LPDRSLIASVPVSVHEs-----sRH------TEGINKVSSLFCELGTDIADPVERLSKVAEANK 343 Nocardia farcin...
BAD59451     277 TGALRNWLLSRG-EglLESSTLRAVVPMSVYVddd--gaDR------VAPASEVSSFLIDLPVGEPNPVMRLSHISHATE 347 Nocardia farcin...
CAD95354     276 AGALGNWLMSRG-EavAPTATVRAMAPLSVYAddqldstGP------GQAISQVTPFLVDLPVGEGNAVVRLSQIAHATE 348 Mycobacterium b...
CAB61924     258 AGALRRWLDERG-Dg-SEGVAPRALIPVSRRRp-----rSA------HPQGNRLSGYLMRLPVGDPDPLARLGTVRAAMD 324 Streptomyces co...
WP_011399653 281 SEVLTRYLHSLN-E--NVERPLIAVSPISVRSk-----rID------SPTGSQLSAMLISLATNEPNLAIRLKSIHDNAT 346 Hahella chejuensis
WP_011395041 281 SGGLRRLLQERM-Dq-VDGVRLHATLPVNLRPl-----eTRlgreqlQELGNQFGTVFVPLAAGIGNPIERLYKIKHDMA 353 Hahella chejuensis
WP_011395160 268 AGALRYYLVERCiE--LDVDTIHAAVPFNLRPmd----ePI------DALGNQFGLVIAPLPIGIHDVAERFEAVRRDML 335 Hahella chejuensis

CAI48224     357 GKRAGIQAFLMYALLTIGGHVPEYVQKKVMTLFEDRA---------TGVVTNVPGPTDAIQFAGREITDMIFWVPQANEQ 427 Natronomonas ph...
AAK47554     328 RAKAGGQRQFGNTLMAIANRLPFPMTAWAVGLLMRLPqr-----gvVTVATNVPGPRRPLQIMGRRVLDLYPVSPIAMQL 402 Mycobacterium t...
AAK47818     297 QSGRRQPD-------SLSDYTPLMLCAKMIHALARLPqq-----giVTLATSAPRPRHQLRLMGQKMDQVLPIPPTALQL 364 Mycobacterium t...
BAD56419     344 GAKDEHELIGSDFLQDWTQYAPPNTFRLAMRLYSSFKlaerhpvvhNLVVSNVPGPPMPLYFLGVKVLGIYPFGPVFHGA 423 Nocardia farcin...
BAD59451     348 ANGRHHRGVRARTLVHLAGFAPASLHAMSVRAASTFAeh-----tfNLVITNAPGPQQPMYIGGARMLEMYPVSPLLRNQ 422 Nocardia farcin...
CAD95354     349 SNPTAASLVDARTIVTLSGLAPATLHAMGVRVATSFSar-----lfNLLITNAPGTQSQMYIAGTKLLETYSVPPLLHNQ 423 Mycobacterium b...
CAB61924     325 RNKDAGPGRGAGAVALLADHVPALGHRLGGPLVSGAArl-----wfDLLVTSVPLPSLGLRLGGHPLTEVYPLAPLARGH 399 Streptomyces co...
WP_011399653 347 SSQIYGQAI---SAARLTQLIPSSMLGLSARIYTEFQlaqrhkplfNIPITNIPGPQTPLYFNGTKVTRQLGSAPLFDGL 423 Hahella chejuensis
WP_011395041 354 ALKESMQPSLSHALLTAMGLFPQGVQQPLLELFSNKT---------SMVLSNVPGARRARYLAGSKVKELMFWVPQTGDI 424 Hahella chejuensis
WP_011395160 336 ALKHSQQAKAFYGLLGLLGKGPDFLEQTALETLSRKA---------SMVITNVPGPKQALYLAGSKLLTPMIWAPQSGEV 406 Hahella chejuensis

CAI48224     428 GIGISIFSYDGNVRVGVAADENLLGAPGELAAAFEAEMEALLEDA 472 Natronomonas pharaonis DSM 2160
AAK47554     403 RTSVAMLSYADDLYFGILADYDVVADAGQLARGIEDAVARLVAIS 447 Mycobacterium tuberculosis CDC1551
AAK47818     365 STGIAVLSYGDELVFGITADYDAASEMQQLVNGIELGMARLVALS 409 Mycobacterium tuberculosis CDC1551
BAD56419     424 GLTITALSNNGHLDFGLIACKELVPDVHELANEIPDALEELRQAA 468 Nocardia farcinica IFM 10152
BAD59451     423 ASSIGITSYDGRVFYGLNGDRDAMADIGVLAAAVHESLEEMLGAC 467 Nocardia farcinica IFM 10152
CAD95354     424 ALAISVTSYNGMLYFGINADRDAMSDVDLLPGLLSQALDELLEAS 468 Mycobacterium bovis AF2122/97
CAB61924     400 SLAVAVSTYRGRVHYGLLADAKAVPDLDRLAVAVAEEVETLLTAC 444 Streptomyces coelicolor A3(2)
WP_011399653 424 GLSIVVVSYNGEVTFTLTSNPKTISSPEELTKHFESAITQLEKDl 468 Hahella chejuensis
WP_011395041 425 GLGVSLLSYNQSVQIGINADRALLPEPAELTRAMIDALEEYRSLt 469 Hahella chejuensis
WP_011395160 407 GVSLSVISYNGAIQFGVAVDQGLIPDPDKLANHFVDAFAELQALA 451 Hahella chejuensis
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