Conserved Protein Domain Family
TraA_Ti

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TIGR02768: TraA_Ti 
Ti-type conjugative transfer relaxase TraA
This protein contains domains distinctive of a single strand exonuclease (N-terminus, MobA/MobL, pfam03389) as well as a helicase domain (central region, homologous to the corresponding region of the F-type relaxase TraI, TIGR02760). This protein likely fills the same role as TraI(F), nicking (at the oriT site) and unwinding the coiled plasmid prior to conjugative transfer.
Statistics
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PSSM-Id: 274289
Aligned: 6 rows
Threshold Bit Score: 1033.99
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
cucgc:lpg1241       7 VAIAFAQVSIHSRSKGHSAVAAAAYRSGARLYDDRIGRAYDFSKRDD-VAFSEILLPDGTTD---------SF-L-ERDY 74   Legionell...
goetting:GOX2713    1 MAIYHLHAKVISRATGRSAVAAAAYRAACRLHDVRLDRDHDFSNKSG-VVHSEILLPDGAPE---------RF-L-DRAT 68   Gluconoba...
ABB59509            1 MAIAHFSASIVSRGSGRSVVLSAAYRHCAKMEYEREARTIDYTRKQG-LLHEEFVLPADAPKwvrsliadrSV-SgASEA 78   Agrobacte...
WP_010974226        1 MAIYHLSTKPVSRSSGRSAVASAAYRCAVLLVNQRDGLVHDFTRKEG-VAHSEIVLPQGVSA---------GWaL-DRST 69   Agrobacte...
WP_011053391        1 MAIMFVRAQVISRGSGRSIVSAAAYRHRARMMDEQAGTSFSYRGGAGeLMYEELALPDEIPDwlrsaisgqSV-SkASEV 79   Rhizobium...
AAP22627           58 MAIYHLNTHTIGRAAGHSAVAAAAYRSASSLVDERTGEVFDFTRKGG-VLSSEIVTPAGVPV---------P----ERAA 123  Pseudomon...
cucgc:lpg1241      75 LWNEVERAENRSNSQLCKDFVLALPRELNLEQQIELAKRFARTHFVEKGLPADIAIHd----HGDGNPHAHILIPTRRLE 150  Legionell...
goetting:GOX2713   69 LWNEVEAIEKRKDAQLAREVEFSIPREMTQAQGIALARDFVREQFVERGMVADLNVHwdigeDGQAKPHAHVMLSTRSVD 148  Gluconoba...
ABB59509           79 FWNKVEAFEKRADAQLARDLTIALPLELSAEQNIALVRDFVENHILAKGMVADWVYH-----ENPGNPHIHLMTTLRPLS 153  Agrobacte...
WP_010974226       70 LWNAAEFAEKRKDARVAREFEIALPHELSPEGRLKAARAFAQDLANRYGAAVDFAIHspsehGDIRNHHAHVLMTTRQVG 149  Agrobacte...
WP_011053391       80 FWNAVDAFETRADAQLARELIIALPEELTRAENITLVREFVRDNLTSKGMIADWVYH-----DKDGNPHIHLMTTLRPLT 154  Rhizobium...
AAP22627          124 LWNAAETAEKRKDARVAREWRAALPHELNEADRKELATRMGQAIADRYGVAVDVCIHapdkeGDDRNFHVHMLATTRTIQ 203  Pseudomon...
cucgc:lpg1241     151 NNR-FSKYKArdl-------------------npvFAKgFLVEQDYWGEQWREMQNEFFIENNLDLQVDAN-------HL 203  Legionell...
goetting:GOX2713  149 ENG-FGAKER-------------------------SWN-DKELLLTWRERWASLANERLAELDLDVRIDHRsfaaqgiDL 201  Gluconoba...
ABB59509          154 DES-FGSKKVavigedgqpv-----rtksgkilyeLWAgSTDDFNVLRDGWFERLNHHLALGGIDLKIDGRsyekqgiNL 227  Agrobacte...
WP_010974226      150 KAG-LGEKTClehkna--------------rllanGMAtTDMQLRDIRQSWEGIANRQLQHEGLDVRIDHRshierglEL 214  Agrobacte...
WP_011053391      155 EEG-FGAKKVpvlgeggkplrvvtpdrpngkivykVWAgDKETMKAWKIAWAETANRHLALAGHDIRLDGRsyaeqglDG 233  Rhizobium...
AAP22627          204 ADGtLGAKAVielank-------------drqkagIPGtSQGDIIEIRQQWAELTNEALERAGISARVDHRsyadqgvEL 270  Pseudomon...
cucgc:lpg1241     204 IAERHRGKH-----HNANAHYLLEE------NQLIQQARMELTRDNIDLVIDHLSTQYSVFTRRDVERLLFKtfQAsDSP 272  Legionell...
goetting:GOX2713  202 EPQNKIGPAgmrreERGEDAERVAD------HLEIARRNGERLLAEPHVALEALTQQQSTFTRQDMARFVDR--QT-VDA 272  Gluconoba...
ABB59509          228 EPTIHLGVGakaieRKAEQRGVRPElervelNEQRRSENTRRILNNPAIVLDLITREKSVFDERDVAKVLHR--YI-DDP 304  Agrobacte...
WP_010974226      215 SPTEHMGVHasqmrQQGMAVERGRL------DDEAARQNAALIRQKPEQVLTLISHEKSVFDRHDIAKTLHR--YInDDA 286  Agrobacte...
WP_011053391      234 IAQKHLGPEkaalaRKGRELHFAPA------DLARRQEMADRLLSEPELLLKQLGNERSTFDERDIARALHR--YV-DDP 304  Rhizobium...
AAP22627          271 TPTKHIGSDavamdRRGLEADRIDI------HNADRQEQARQIVERPEIILDKLTATQAVFTRRDIAAELNR--YI-DDA 341  Pseudomon...
cucgc:lpg1241     273 QEYLQFVERVLGHQDLVALG----DNNKGe---PS-FTTRTHLMQEAQLLHDIEAMMVSKNHVVHQPI--DSLa------ 336  Legionell...
goetting:GOX2713  273 EQFTAVMVRVEACPELVALG----KDGHG----RErFSTRAMIGVEQRLEEASLAMGQSQGHAVPLAVrrAAM------- 337  Gluconoba...
ABB59509          305 ALFQQLMIKIILNRQVLRLQretiDFSTGek-lPArYSTRAMIRLEATMARQATWLSNREGRGVSPTAldATFr------ 377  Agrobacte...
WP_010974226      287 QTFQNAFAAVLASSALVELQaeriDPGTGkv-sNArYSTREMIDLELAMARSAVRLHQAQSHGVDPRHvdRAIerqdrsl 365  Agrobacte...
WP_011053391      305 TDFANIRARLMASDQLVILKpqeiEAETGkvsePAvFTTREMLRIEYDMAQSARVLSERRGFGVSERNvtVAIervesi- 383  Rhizobium...
AAP22627          342 DQFQGLLARLEKSPLLVEM-----EPANGr--dPAkFSTREMIDTERGMVDSAERLARTGRHGVSGPItnAAId------ 408  Pseudomon...
cucgc:lpg1241     337 ------------QQYRLSEEQYEAFRYITQSPDISVVIGRPGTGKSYLLKPLNEYYIQAGMEVIGAALSGKVAKALQAET 404  Legionell...
goetting:GOX2713  338 ------------QHSGLGEEQALAVGEVTKSRDLSVVVGYAGTGKSTMLGVARAAWEEAGYRVRGAALSGIAAEGLEAGC 405  Gluconoba...
ABB59509          378 ------------RHERLSDEQKAAIEHVAGPARIAAVVGRAGAGKTTMMKAAREAWELAGYHVVGGALAGKAAEGLEKEA 445  Agrobacte...
WP_010974226      366 rrssggmlaasdPSAGLSDEQRHAIKHITGSERIAVVVGFAGAGKSTMLTAARKAWEAQGYQVHGAALSGKAAEGLEESS 445  Agrobacte...
WP_011053391      384 ------esgdpkTPFRLDAEQVDAVRHVTGDGGIAAIVGLAGAGKSTLLAAARLAWESEGHRVIGAALAGKAAEGLQDSS 457  Rhizobium...
AAP22627          409 ------------GAGTLSAEQQNAVRHVLKPGSLAVVIGDAGTGKSFSMKVAREAWQAQGFNVRGAALAGKAADELQAGS 476  Pseudomon...
cucgc:lpg1241     405 GITSSTIKSLSYRLANDMMQLSDKHVLIIDEAGMVDFSSMGYLIKEAHKAGSKVVLIGDPDQLKPIQKGEIFRGIAARTG 484  Legionell...
goetting:GOX2713  406 GIESRTLASLERAWERGFDLLERGDVLVVDEAGMVGSRQMERVLSVAREAGAKVVLVGDPEQLQAIEAGGAFRAVAERVG 485  Gluconoba...
ABB59509          446 GIQSRTLASWELRWKRGRDLLDDKTIFIMDEAGMVASKQMAGFVDTAVRAGAKIVLVGDPEQLQPIEAGAAFRAIADRIG 525  Agrobacte...
WP_010974226      446 GIESRTLASWSYSWDQGRNLIGSSDLFVIDEAGMVGSRQLARFIGEAEERGAKIVLVGDHEQLQAIGAGAPFRAIAEQIG 525  Agrobacte...
WP_011053391      458 GIKSRTLASWELAWANGRDTLHRGDVLVIDEAGMVASQQMARVLKIAEEAEVKVVLVGDAMQLQPIQAGAAFRAITERIG 537  Rhizobium...
AAP22627          477 GIDSRTLASLEFAWKNGKDKLTSRDVLVIDEAGMIGSRQLGRVLKAAEQAGAKVVLLGDDKQLAAIEAGAAFRGVVQHVG 556  Pseudomon...
cucgc:lpg1241     485 YIELENIKRQQDLGDRQASLNLAKGDIDKAIQHYQDKGAITITDTKLQAIEQVVADWKQDlESTNMADS----------- 553  Legionell...
goetting:GOX2713  486 SVEITTVRRQREGWQQAATKELATGRTGEALGRYEAAGLVRGHDTLEEARAGVVAGWDEA-RQAAPEESq---------- 554  Gluconoba...
ABB59509          526 YAELETIYRQREEWMRKASLDLARGNVENALSAYRANVRITGERLKAEAVERLIADWN---HDYDQTKTi---------- 592  Agrobacte...
WP_010974226      526 HVELSGIRRQRHDWQRQASVAFATHKTAEGLAAYRDHGDIHFAESRDAAMAQIVRDYIDD-NEKRPDGTr---------- 594  Agrobacte...
WP_011053391      538 FAELAGVRRQREAWARNASRLFARGEVEKGLDAYARHGHLVEAGTREETIDRIVSDWAAArREAIERSTsegrdgrlrgd 617  Rhizobium...
AAP22627          557 AAEITEVRRQKEAWARAAGQELARGSVADGLAAYAERGHVKIHDSRDAARDSLAAAYVGDqGK----GSq---------- 622  Pseudomon...
cucgc:lpg1241     554 --IMLSYTRKAVNHLNDLAREALIVENKIGEEn-------------------------IVYQGLERSLKISTGERLLLRE 606  Legionell...
goetting:GOX2713  555 --IMLAHRRVDVRALNEAAREIRREAGELGDD--------------------------VLVPTAQGERVFADGERVYFLR 606  Gluconoba...
ABB59509          593 --LILAHLRRDVRMLNVMAREKLVERGMVGEG--------------------------HLFRTADGERRFDAGDQIVFLK 644  Agrobacte...
WP_010974226      595 --VAMAHRRADVRALNATIRSELQNRQRLERSlglsdgpdrgdrgdvedrgnsgdvaeLTFQTSNGKRAFASGDRIIFLE 672  Agrobacte...
WP_011053391      618 elLVLAHTNDDVRKLNEALREVMAGDNALGES--------------------------RSFRTERGARKFAAGDRIIFLE 671  Rhizobium...
AAP22627          623 --IILAHSNKDVQALNEAVREARKERGELRGT--------------------------ARFMTERGGREFAPGDRIVFLK 674  Pseudomon...
cucgc:lpg1241     607 NNKVLG----------VRNGDTATVKEINVQ------Q----MKIQLD--S------G---ELLIIP-KEYKALDYAYAL 654  Legionell...
goetting:GOX2713  607 NDRELG----------VKNGTLGTVRGITGSaeagdlA----LSVQLD--GaggagrG---RVVSVSvAEYDALDHGYAA 667  Gluconoba...
ABB59509          645 NEGSLG----------LKNGMIGHVVVAAAN------R----IVATVG--E------GdqrRQVIVEqRFYNNLDHGYAT 696  Agrobacte...
WP_010974226      673 NNRDLG----------VKNGMLGTVEDVEKG------R----IVARLDgrG------G---DSVSIPtDSYQAIDHGYAT 723  Agrobacte...
WP_011053391      672 NARFLEprakhsgpqyVKNGMLGTVTATGDK------RgdplLSVLLD--N------G---NKVVFGeDSYDNVDHGYAA 734  Rhizobium...
AAP22627          675 NDRDLG----------VKNGTLGTVERAEDG------S----LAVRLD--S------G---EARRFQaAQYAAVDHGYAV 723  Pseudomon...
cucgc:lpg1241     655 TVHKSQGMTAKKVRVLiDSKYWDRNLSFVAMTRHKEQLNIYADKENHPTEQALKQTLSRSSTKDNVIDWPLD-------- 726  Legionell...
goetting:GOX2713  668 TIHKSQGVTVDRAHVL-ATRSLDRHGAYVALSRHRESVSVHWGRDDVGDRNGLVKRLSRERLKDTTLDYPHVrdr--dtg 744  Gluconoba...
ABB59509          697 TIHKSQGATVDRVKVL-ASLSLDRHLTYVAMTRHREDLQLYYGTRSFSFNGGLAKVLSRRQAKETTLDYEHGqfyrealr 775  Agrobacte...
WP_010974226      724 TIHKNQGATVDRAFVL-ASSTMDRHLAYVAMTRHRDSVQLYADIKEFTSAGRLVdhgvapyehnrrarenyfvtlendkg 802  Agrobacte...
WP_011053391      735 TIHKSQGSTVDRTFVL-ATGMMDRHLTYVSMTRHRDRVDLYAAKEDFEprpewgrkprvdhaagvtgelvetgeakfrpe 813  Rhizobium...
AAP22627          724 TIHKAQGVTVDRAYLL-ATPGMDRSLAYVGMTRHREAATLFAGADDFTDRRAgrlvdhgaapyenkpenrasyfatlend 802  Pseudomon...
cucgc:lpg1241     727 FAIRAG 732  Legionella pneumophila subsp. pneumophila str. Philadelphia 1
goetting:GOX2713  745 FARRRG 750  Gluconobacter oxydans 621H
ABB59509          776 FAETRG 781  Agrobacterium tumefaciens
WP_010974226      803 erhtvw 808  Agrobacterium fabrum
WP_011053391      814 dedadd 819  Rhizobium etli
AAP22627          803 ngerht 808  Pseudomonas aeruginosa
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