4AAY


Conserved Protein Domain Family
arsenite_ox_L

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TIGR02693: arsenite_ox_L 
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arsenite oxidase, large subunit
This model represents the large subunit of an arsenite oxidase complex. The small subunit is a Rieske protein. Homologs to both large and small subunits that score in the gray zone between the set trusted and noise bit score cutoffs for the respective models are found in Aeropyrum pernix K1 and in Sulfolobus tokodaii str. 7. This enzyme acts in energy metabolim by arsenite oxidation, rather than detoxification by reduction of arsenate to arsenite prior to export. [Energy metabolism, Electron transport]
Statistics
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PSSM-Id: 274261
Aligned: 4 rows
Threshold Bit Score: 1419.69
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4AAY_A     9 RLPIIPADAKKHNVTCHFCIVGCGYHAYTWPINKQGGTDPQNNIFGVDLSeQQQAESDAWYSPSMYNVVKQ-DGRDVHVV 87  arsenite-oxidising ...
Q8GGJ6     7 RVALPPVNAQKTNMTCHFCIVGCGYHVYKWDENKEGGRAANQNALGLDFT-KQLPPFATTLTPAMTNVITAkNGKRSNIM 85  Herminiimonas arsen...
AAR05656   9 RLPIIPADAKKHNVTCHFCIVGCGYHAYTWPINKQGGTDPQNNIFGVDLSeQQQAESDAWYSPSMYNVVKQ-DGRDVHVV 87  arsenite-oxidising ...
BAD71923   9 RLPIPPKNAKVYNQVCQYCTVGCGYKVYVWPVGEEGGVKPEQNAFGLDLStPQPPLAGQSYTETMHAVTVGrDGRQYNVV 88  Thermus thermophilu...
4AAY_A    88 IKPDHECVVNSGLGSVRGARMAETSFSEARNTQQqRLTDPLVWRYGQMQPTSWDDALDLVARVTAKIVKEKGEDA-LIVS 166 arsenite-oxidising ...
Q8GGJ6    86 IIPDKECVVNQGLSSTRGGKMAGYMYAADGMTAD-RLKYPRFYAGDQWLDTSWDHAMAIYAGLTKKILDQGNVRD-IMFA 163 Herminiimonas arsen...
AAR05656  88 IKPDHECVVNSGLGSVRGARMAETSFSEARNTQQqRLTDPLVWRYGQMQPTSWDDALDLVARVTAKIVKEKGEDA-LIVS 166 arsenite-oxidising ...
BAD71923  89 IVPAKDSPINRGNYSIRGGTNALTVWSLDRGTQD-RLTYPLLRVGDQFQAITWQDALTLMGLLIKGIRDRDGNDDnIAVK 167 Thermus thermophilu...
4AAY_A   167 AFDHGGAGGGYENTWGTGKLYFEAMKVKNIRIHNRPAYNSEVHGTRDMGVGELNNCYEDAELADTIVAVGTNALETQTNY 246 arsenite-oxidising ...
Q8GGJ6   164 TFDHGGAGGGFENTWGSGKLMFSAIQTPTVRIHNRPAYNSECHATREMGIGELNNSYEDAQVADVIWSIGNNPYETQTNY 243 Herminiimonas arsen...
AAR05656 167 AFDHGGAGGGYENTWGTGKLYFEAMKVKNIRIHNRPAYNSEVHGTRDMGVGELNNCYEDAELADTIVAVGTNALETQTNY 246 arsenite-oxidising ...
BAD71923 168 CFDHGGSGQGFEDNYAAGKLFFAALSVKHIAIHNRPAYNSEVWGSRERGVHELNYTYEDARLADTIVLWGANSYETATVF 247 Thermus thermophilu...
4AAY_A   247 FLNHWIPNLRGESLGKKKELM-PEEPHEAGRIIIVDPRRTVTVNACEQTAgADNVLHLAINSGTDLALFNALFTYIADKG 325 arsenite-oxidising ...
Q8GGJ6   244 FLNHWLPNLNGSTEEKKKQWF-AGEPVGPGLMIFVDPRRTTSIAIAEQTA-KDRVLHLDINPGTDVALFNGLLTYVVQQG 321 Herminiimonas arsen...
AAR05656 247 FLNHWIPNLRGESLGKKKELM-PEEPHEAGRIIIVDPRRTVTVNACEQTAgADNVLHLAINSGTDLALFNALFTYIADKG 325 arsenite-oxidising ...
BAD71923 248 YVEHMLPNIQGATVAEKQQAFdPGEPAEPGYLIVIDPRKTSSYTVAAQVA-PDRVMLLRPNLGTDYILANAIARAVWEKG 326 Thermus thermophilu...
4AAY_A   326 WVDRDFIDKstlregtarpplypargvseanpgHLSSFED-AVEGCRMS------IEEAAEITGLDAAQIIKAAEWIGMP 398 arsenite-oxidising ...
Q8GGJ6   322 WIAKEFIAQ------------------------HTVGFED-AVKTNQMS------LADCSRITGVSEDKLRQAAEWSYKP 370 Herminiimonas arsen...
AAR05656 326 WVDRDFIDKstlregtarpplypargvseanpgHLSSFED-AVEGCRMS------IEEAAEITGLDAAQIIKAAEWIGMP 398 arsenite-oxidising ...
BAD71923 327 YYDMAYLQAr----------------------tDMTLFEEyKAKSLKLSvpydefMAQAERITGVSRAEIEKAADWIAKP 384 Thermus thermophilu...
4AAY_A   399 KEGGKRRRVMFGYEKGLIWGNDNYRTNGALVNLALATGNIGRPGGGVVRLGGHQEGYVRPSd-----aHVGRPAAYVDQL 473 arsenite-oxidising ...
Q8GGJ6   371 KAAGKMPRTMHAYEKGIIWGNDNYNIQSSLLDLVIATQNVGRRGTGCVRMGGHQEGYVRPP-------HPTGEKIYVDQE 443 Herminiimonas arsen...
AAR05656 399 KEGGKRRRVMFGYEKGLIWGNDNYRTNGALVNLALATGNIGRPGGGVVRLGGHQEGYVRPSd-----aHVGRPAAYVDQL 473 arsenite-oxidising ...
BAD71923 385 KAGRFKRRTLTIYEKGIIWNMKNYDQVAAIVQLAVLTHNIGRPGTGCGRQGGHQEGYVRPPaptpgsiYRGGPPVNVDKF 464 Thermus thermophilu...
4AAY_A   474 LIGGQGGVHHIWGCDHYKTTLNAHEFKRVYKKRTDMVKDAMSAAPY-GDREAMVNAIVDAINQG--GLFAVNVDIIPTKI 550 arsenite-oxidising ...
Q8GGJ6   444 IIQGKGRMMTWWGCNNFQTSNNAQALREVSLRRSQIVKDAMSKARG-ASAAEMVDIIYDATSKG--GLFVTSINLYPTKL 520 Herminiimonas arsen...
AAR05656 474 LIGGQGGVHHIWGCDHYKTTLNAHEFKRVYKKRTDMVKDAMSAAPY-GDREAMVNAIVDAINQG--GLFAVNVDIIPTKI 550 arsenite-oxidising ...
BAD71923 465 LIEGKGKFYWVIANDPYLSTPNNQVFRKRIHERTEKLTKALGAGGEpGTIQERAQKILDILYQDpdALFLVVQDIYMTET 544 Thermus thermophilu...
4AAY_A   551 GEACHVILPAATSGEMNLTSMNG-ERRMRLTERYMDPPGQSMPDCLIAARLANTMERVLTEMGDVGYAAQFK-GFDWQTE 628 arsenite-oxidising ...
Q8GGJ6   521 SEAAHLMLPAAHPGEMNLTSMNG-ERRMRLSEKFMDAPGDALPDCLIAAKAANTLKAMYEAEGKPEMVKRFS-GFDWKTE 598 Herminiimonas arsen...
AAR05656 551 GEACHVILPAATSGEMNLTSMNG-ERRMRLTERYMDPPGQSMPDCLIAARLANTMERVLTEMGDVGYAAQFK-GFDWQTE 628 arsenite-oxidising ...
BAD71923 545 ARDAHLILPAAGWGEANETSINCnSRLLRLYEKFMDPPGEAKPDWEIFKWVGLRIAELYRAEGKFEEAKKFEfGKNWKTD 624 Thermus thermophilu...
4AAY_A   629 EDAFMDGYNKN-----------AHGGE---FVTYERLSAMGTNGFQEPATGFTDGK-IEGTQRLYTDGvFSTDDGKARFM 693 arsenite-oxidising ...
Q8GGJ6   599 EDAFNDGFRSAgqpga--epidSQGGStgvLATYTLLRAAGTNGVQLPIKRVENGK-MIGTAIHYDDNkFDTKDGKAHFK 675 Herminiimonas arsen...
AAR05656 629 EDAFMDGYNKN-----------AHGGe---FVTYERLSAMGTNGFQEPATGFTDGK-IEGTQRLYTDGvFSTDDGKARFM 693 arsenite-oxidising ...
BAD71923 625 EDVFLAGAEEFrdntvseedeaVLEAEnykGVTYKLLKELGQKGIQTPVRRDPKTGkLVGTVRRYTYR-FGTEDGKFKWY 703 Thermus thermophilu...
4AAY_A   694 -DAPWRGLQAPgKQQQK----DSHKYLINNGRANVVWQSAYLDQENDFVMDRFPYPFIEMNPEDMAEAGLKEGDLVEIYN 768 arsenite-oxidising ...
Q8GGJ6   676 -PAPWNGLPKP-VEEQK----AKHKFWLNNGRANEVWQSAYHDQYNDFVKSRYPLAYIELNPGDAQSLGVAAGDVVEVFN 749 Herminiimonas arsen...
AAR05656 694 -DAPWRGLQAPgKQQQK----DSHKYLINNGRANVVWQSAYLDQENDFVMDRFPYPFIEMNPEDMAEAGLKEGDLVEIYN 768 arsenite-oxidising ...
BAD71923 704 gTDDWEGYPAEvAKYLEpgmaEKYPFWVTTGRAQTIWQTAYHDRHLPEKALALPLPYVEVNPEDAKRLGLKSGDLVEVYN 783 Thermus thermophilu...
4AAY_A   769 DAGATQAMAYPTPTARRGETFMLFGFPTGVQGNVTSAGTN-ELIIPNYKQTWGNIRKI 825 arsenite-oxidising bacterium NT-26
Q8GGJ6   750 DYGSTFAMAYPVKDMKPSHTFMLFGYVNGIQGDVTTDWVD-RNIIPYYKGTWGSVRRI 806 Herminiimonas arsenicoxydans
AAR05656 769 DAGATQAMAYPTPTARRGETFMLFGFPTGVQGNVTSAGTN-ELIIPNYKQTWGNIRKI 825 arsenite-oxidising bacterium NT-26
BAD71923 784 EEGNGTFLVYVTDAVKPGTLFLVMYHWRGTSNSLVTGYTDpKTTIPWYKGTRANLRKV 841 Thermus thermophilus HB8
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