Conserved Protein Domain Family
dot_icm_DotB

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TIGR02524: dot_icm_DotB 
Dot/Icm secretion system ATPase DotB
Members of this protein family are the DotB component of Dot/Icm secretion systems, as found in obligate intracellular pathogens Legionella pneumophila and Coxiella burnetii. While this system resembles type IV secretion systems and has been called a form of type IV, the liturature now seems to favor calling this the Dot/Icm system. This family is most closely related to TraJ proteins of plasmid transfer, rather than to proteins of other type IV secretion systems.
Statistics
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PSSM-Id: 131576
View PSSM: TIGR02524
Aligned: 2 rows
Threshold Bit Score: 705.616
Threshold Setting Gi: 29542204
Created: 8-Oct-2014
Updated: 2-Oct-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
CAH13883             16 FTPVFMDRMLEHAESLNASDITIQTGEPIFAEVYGRLLKITNRRLSNTELGDLINSIYGPNATTQLLSGKDIDTHYEFRP 95  Legionel...
lhbprmlnih:CBU_1645  15 FEPKHIDDLLIYCHRLGASDITIQTGRAVLAEVYGRLQTLTRRELSNAETSDLLNAIYGPNGTTQIMRGEDIDTHYEIRP 94  Coxiella...
CAH13883             96 NRGVRYRYRVNATACLVEGHDAIQITLRTIPTTPPKLSTMSLPDNIIEAIAPQEGIVFITGATGSGKSTLLASIIRELIE 175 Legionel...
lhbprmlnih:CBU_1645  95 NRNERFRYRINGTGCHVDGHEGIQITIRAIPAEPPLLSKLDLPAAIVDAIAPQEGVVYVTGATGSGKSTLLAAIIRELAE 174 Coxiella...
CAH13883            176 TSDSNRKVLTYESPIEFVYDEIETISAVVSQSEIPRHLPNFADGVRNALRRKPRLIMVGECRDAETISAALEAALTGHPV 255 Legionel...
lhbprmlnih:CBU_1645 175 APDSHRKILTYEAPIEYVYDSLTTPTASVCQSEIPRHLNSFAAGVRNALRRKPHAILVGEARDNETISAVLEAALTGHPV 254 Coxiella...
CAH13883            256 YTTLHTSGVAETMRRLVTSFSGEERLGRTIDILETIRLCIWQKLVPTVDERRVALREYLVFDEEVRDILLEGDPNEVTSA 335 Legionel...
lhbprmlnih:CBU_1645 255 YTTLHSSGVAETIRRLVGSFPAEERIGRTIDIIETLRLIIWQRLVPSVDGKRVALREFLVFKEEIRDLLLDSDPEQITAA 334 Coxiella...
CAH13883            336 TRKLVRQKGQLMTWDAKMKFEQGIISERVYKLIIAGAK 373 Legionella pneumophila str. Paris
lhbprmlnih:CBU_1645 335 VRRLVAEHGQPMQVDVEAKFKGGLISERLYKILSASQE 372 Coxiella burnetii RSA 493
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