Conserved Protein Domain Family
NrdD
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TIGR02487: NrdD 
anaerobic ribonucleoside-triphosphate reductase
This model represents the oxygen-sensitive (anaerobic, class III) ribonucleotide reductase. The mechanism of the enzyme involves a glycine-centered radical, a C-terminal zinc binding site, and a set of conserved active site cysteines and asparagines. This enzyme requires an activating component, NrdG, a radical-SAM domain containing enzyme (TIGR02491). Together the two form an alpha-2/beta-2 heterodimer. [Purines, pyrimidines, nucleosides, and nucleotides, 2'-Deoxyribonucleotide metabolism]
Links
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Statistics
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PSSM-Id: 274159
Aligned: 13 rows
Threshold Bit Score: 639.764
Created: 8-Oct-2014
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
CAF29783     187 KDNANLM-HNPESIHKWVADETMKQFALLnVF-PKYIADSHMRGDIHLHDLE-Y-AAV-RTVCCQHDLRNFFKYGLKvdg 261 Methanococcus m...
AAM02114      16 ARNANML-PTPEVISKIFQDRWQKRHFLKhVL-DGKTARAHLEGYIHIHDLD-Y-ALT-RSNCCQHDCRWVLKYGLYarn 90  Methanopyrus ka...
AAM25039     121 NENSNMSySLQG-LNNHISSSITAHYWLNkIY-PPEVRDAHISGDLHIHDLG-----LlSVYCCGWDLRDLLLNGFTg-- 191 Caldanaerobacte...
BAB80623      20 NENSNSP-YSFGSLNKHIIAEVSKDYWLNeVYkDKRIIDAYKNGDMHIHDLG-----GlTLYCCGYSLRNIILMGVQg-- 91  Clostridium per...
WP_000940077  29 QENANVDgRSPMGVMGTFASESAKYYAVEnLL-SDQVKKAINENILYPHDLD-F-YATgTTTCSQIPLAQMLANGFH--- 102 Bacillus cereus
AAA24226     115 NENANKDsKVIPTQRDLLAGIVAKHYARQhLL-PRDVVQAHERGDIHYHDLD-YsPFFpMFNCMLIDLKGMLTQGFK--- 189 Escherichia col...
WP_011016303 113 SENANKDaKTISVQRDLLAGISSRDYYLNkIV-PEHIKLAHIKGEIHLHDLD-Y-LLFrETNCELVNIEAMLKGGCN--- 186 Fusobacterium n...
WP_006768369 125 AENGNKDaRTFTTQREILAGAVSKAKGLQ-ML-PEDIRRAHLKGLIHVHDLDrS-PFAaMPNCSLPDFDYLLSHGFT--- 198 Corynebacterium...
WP_010963802 113 RDNANVg-NNYSSKLLRIASESNKWHNLS-AM-PKKISRAHENGDIYLHDLD-S-YNl-SINCLHIPTKEVLQSGFN--- 183 Clostridium ace...
WP_012458242 119 lgNANMSsHTPAGQMMTFASEVTKDYASKyLL-SLRYSRAHRAGDIHIHDLD-Y-YPTkTTTCVQYDIADLYERGFR--- 192 Porphyromonas g...
WP_011077320 119 KENSNSDsALVSTKRSLIFNELNKALYKKfFL-TTDELQAFNDGYIYIHDS--S-ARRdTMNCCLFDLANVLKGGFE--- 191 Mycoplasma pene...
WP_011020131 163 NDNAN-QlNNAETSHKRKADKMSKEQNLL-LM-PKELADLHLNGDFHIHDLE-Y-MGT-RPFCQDWDLRYFFYYGLMpdg 236 Methanosarcina ...
WP_011013113  19 lENANRy-PGPSGFFAYVMEEALKS--SLsLI-PEVGLRAHFSGDIYIHKLP-Y-S-LyIPYCTGHSIARLLKRGLR--- 88  Pyrococcus furi...

CAF29783     262 -tgR-HTS-VSKPAKHPDVALQHAAKVLSAAQCEMSGGQSIDEFNIWIAPYM--RGLEYSEVRQLMQLFIy--------- 327 Methanococcus m...
AAM02114      91 pigR-LTC-VSKPAKHAEVAVLHILKWLMTSQNFFAGGQGQDFVNFLVAPYIaeEGLSYEEIRQLAQIMMf--------- 159 Methanopyrus ka...
AAM25039     192 ---VeGKV-QSKPPKHFRSALGQIVNFFYTLQGEAAGAQAFSNFDTYLAPFV--YYDNLSYREVKQAMQEfifn------ 259 Caldanaerobacte...
BAB80623      92 ---I-PNIpTSSPAKHFDAILNQIANLVTIYQNEIMGAVAFNSFDTLLAPYI--KKDNLTYEEVKQNLQNfifs------ 159 Clostridium per...
WP_000940077 103 ---T-GHG-HMRQPQDIKSALALSSIIFQANQNMQHGGQSFALFDVDLAPYV--RKTVERHKKRLQSYPLtk-------- 167 Bacillus cereus
AAA24226     190 ---M-GNA-EIEPPKSISTATAVTAQIIAQVASHIYGGTTINRIDEVLAPFV--TASYNKHRKTAEEWNip--------- 253 Escherichia col...
WP_011016303 187 ---I-GNA-KMLEPNSVDVAVGHIVQIIASVSSNTYGGCSIPYLDRALVRYI--KKTFKKHFLRGAKYIDdlneeqieel 259 Fusobacterium n...
WP_006768369 199 ---L-GNA-RIEPPRSIGVAATLLVQLLGAISGEQYGGISIHEIDRLLEPYA--ELTLQKNRRLYSDASGllcsdsa--- 268 Corynebacterium...
WP_010963802 184 ---T-GYG-YIRPPKRIESAAELSCILLQSTQNDMFGGQSHPDFDNDMAEFI--EETRRQIRHEYEEIGVea-------- 248 Clostridium ace...
WP_012458242 193 ---T-KNG-SIRTPQNIHSYATLATIIFQTNQNEQHGGQAIPAFDFFMAPGV--RKSFVTHLIERLRFVLel-------- 257 Porphyromonas g...
WP_011077320 192 ---M-GNI-WYNEPKTLSSAFNVIGDVVLSTAAQQYGGFTLPEIDKILGKYA--KLSYEKYLNKYLSLGLny-------- 256 Mycoplasma pene...
WP_011020131 237 -vgT-QSS-VAKPAKNAEVAFLHAVKAMGSAQTNFAGGQGFYNFLTFIAPYL--EGKSEVEIKQLMQMFVye-------- 303 Methanosarcina ...
WP_011013113  89 ---T-PTI-TSRPAKHFDTFVDHIANYLITLQHYFSGAQAFSSVEWYAGPFI--RKENLDLRKVKQNIQRlvyn------ 155 Pyrococcus furi...

CAF29783     328 -----------------eMN-------------------------------------------------QIYAARGGQVV 341 Methanococcus m...
AAM02114     160 -----------------eAT-------------------------------------------------QDLVARGGQPA 173 Methanopyrus ka...
AAM25039     260 ---------------lnvPT-------------------------------------------------RVGFQTPFTNI 275 Caldanaerobacte...
BAB80623     160 ---------------insNS-------------------------------------------------RAGAEPAFTNI 175 Clostridium per...
WP_000940077 168 ----------------eqIE-------------------------------------------------EFAWKETENDT 182 Bacillus cereus
AAA24226     254 -----------------dAE-------------------------------------------------RYANSRTIKEC 267 Escherichia col...
WP_011016303 260 kkenleysneiiknkypkTY-------------------------------------------------EYSVDMTEESV 290 Fusobacterium n...
WP_006768369 269 -----------tdaqddlVE-------------------------------------------------ELARRKTAKDI 288 Corynebacterium...
WP_010963802 249 ----------------dkLD-------------------------------------------------EYVEKKLVRIV 263 Clostridium ace...
WP_012458242 258 ----------------rqPTntdlsttlpkairnltplltdspqeagrlyeglcsasfpfssteveialATAFRKTRKDT 321 Porphyromonas g...
WP_011077320 257 ----------------dkAQ-------------------------------------------------EVALSDLENDF 271 Mycoplasma pene...
WP_011020131 304 -----------------mMQ-------------------------------------------------MMCARGGQT-V 316 Methanosarcina ...
WP_011013113 156 ---------------lnyPT-------------------------------------------------RIGLQTPFTNF 171 Pyrococcus furi...

CAF29783     342 FSSINLELEVP----E-YLKGKDA-IKAGQVVGA--YEEYDYEVKMIAEALVDVLMDGD---Ay-gKPFLFPNVIFKLRE 409 Methanococcus m...
AAM02114     174 FTNVNLELTCP----D-FLEDEPAvGPGGEIVGT--YGDFEEEAIMFARALLDVQLEGD---Aa-gAPLKFPQIIVKVRP 242 Methanopyrus ka...
AAM25039     276 TMDLVVPEIMA----D-EPVIIGG---KIMDRTY--K-EFQKEMDMINMAFAVVMMEGD---Ak-gRIFTFPIPTYNITK 340 Caldanaerobacte...
BAB80623     176 TFDLFPPKDLE----N-DPALIGD---KIQEFTY--K-ECQKEMDMLNKAFYELMNEGD---Yn-gRPFSYPIPTYNINS 240 Clostridium per...
WP_000940077 183 YQACEAFIHNS----N-SMHSRGGgQVPFISINY--GTDTSKEGRLLIKQLLKATQAGL---Gk-gETPIFPIQIFKMKK 251 Bacillus cereus
AAA24226     268 YDAFQSLEYEV----N-TLHTANG-QTPFVTFGF--GLGTSWESRLIQESILRNRIAGL---GknrKTAVFPKLVFAIRD 336 Escherichia col...
WP_011016303 291 KQAMQGLEYEI----N-SLSTVNG-QTPFTTVGI--GTETSWEGRLVQKYVLKTRMAGF---GakkETAIFPKIVYAMCE 359 Fusobacterium n...
WP_006768369 289 FDAMQAFEYQV----N-TLTTAAA-QTPFTSISL--GMTTSWCGREIQKSILAVRENGM---Sg--ETAIFPKIIFFVDE 355 Corynebacterium...
WP_010963802 264 GQSMQGIVYNL----N-TMHSRAGsQVPFSSINI--GIPQSKDAALVCEIFLKEYEKGL---Gn-gEQPIFPNIIFRVKS 332 Clostridium ace...
WP_012458242 322 HQAMEGFIHNL----N-TMHSRGGnQVVFSSINY--GTDTSPEGRMVMEELLRATEEGL---Gh-gEVPIFPIQIFKVKE 390 Porphyromonas g...
WP_011077320 272 TQGWQGIEYKF----N-TVGSSRG-DYPFIAITI--GLGTDQFSKMAAKTCLQVRAKGQgeeGk-kRPVLFPKIVFLYDE 342 Mycoplasma pene...
WP_011020131 317 FSSVQLSPGVPklwkN-IPVVAMGkVWDGKHAPLrtYGEFEKEVRLGFKALMDVMLEGD---Aw-gKPFSFPKPEISLEP 391 Methanosarcina ...
WP_011013113 172 TVTLDAPKKML----EgDYAIYNG----EEVAPL--G-EYEREAKMFILALTEVLREGD---Al-gQPFTFPIPTLMVTA 236 Pyrococcus furi...

CAF29783     410 NafKDE----------NKd-----------------------lLVKIHELSAKWGLPYFIN---MFADYQhg------nT 447 Methanococcus m...
AAM02114     243 G--YDK----------ET-------------------------LELAFEVAAENGAVYFAN---MLNRDWr-------kL 275 Methanopyrus ka...
AAM25039     341 NfdWDS----------PV-------------------------VNKVMEMTAKYGLPYFSN---FVNSDLdpn----dvR 378 Caldanaerobacte...
BAB80623     241 NfdFDN----------PN-------------------------NDMLFEMTGKFGYPYFAN---FVNSDMdqs----dvR 278 Clostridium per...
WP_000940077 252 GvnFEE----------CDpny--------------------dlFELALETTAERLFPNFSF---LDAPFNavh---ydgR 295 Bacillus cereus
AAA24226     337 GlnHKK----------GDpny--------------------diKQLALECASKRMYPDILN---YDQVVKvtg----sfK 379 Escherichia col...
WP_011016303 360 GlnLNE----------GDpnw--------------------diSQLAFECMTKSIYPDILF---ITPEQLkne----tvV 402 Fusobacterium n...
WP_006768369 356 GvnHAP----------GDpny--------------------diKMAAMRCSMRRIYPDLVS---VPRIRElkq----gqL 398 Corynebacterium...
WP_010963802 333 GvnRNE----------NDpyy--------------------ylFKLACRVAAKRMNPTFMN---IDADFNkeyydkgyiP 379 Clostridium ace...
WP_012458242 391 GinYSE----------ADvksalenfddamagkvlfsapnfdlLLKACATTAKALFPNFVF---LDTPFNlhe----dwR 453 Porphyromonas g...
WP_011077320 343 NlhGEN----------KVne---------------------dlFEEGVLCSSKTMYPDWLS---LTGEGYvcd----iyK 384 Mycoplasma pene...
WP_011020131 392 DfmQEDesfneahpeiPTyk---------------------elYRLTFELAAKFGTPYFDN---QLPEYRgag---egiS 444 Methanosarcina ...
WP_011013113 237 DmiWND----------Pe------------------------vFEAIFTTAAKRGSFYWLNtnvVDPDA----------S 272 Pyrococcus furi...

CAF29783     448 ------N-----------AMGCRTRLSGEWG-------NS------I--------EESSLRTG-----------NMQ--- 475 Methanococcus m...
AAM02114     276 vgd-nvN-----------YMGCRTCLATNWT-------GD------W--------EIDTIRTG-----------NFE--- 308 Methanopyrus ka...
AAM25039     379 ------------------SMCCRLRLDNRELrr---rgGG------L--------FGANPLTG-----------SIG--- 409 Caldanaerobacte...
BAB80623     279 ------------------SMCCRLNLDLRELrk---rnGG------L--------FGSGDSTG-----------SIG--- 309 Clostridium per...
WP_000940077 296 pes-evC-----------YMGCRTRVMSNIH---------------G--------EETAIGRG-----------NLS--- 326 Bacillus cereus
AAA24226     380 ------T-----------PMGCRSFLGVWEN-------EN------G--------EQIHDGRN-----------NLG--- 407 Escherichia col...
WP_011016303 403 ------Y-----------PMGCRAFLSPWKD-------KN------G--------KEKYAGRF-----------NIG--- 430 Fusobacterium n...
WP_006768369 399 i-----T-----------PMGCRSFLHPWKN-------SD------G--------DYELLGRN-----------NLG--- 427 Corynebacterium...
WP_010963802 380 ------A-----------TMGCRTYLMSNIN---------------G--------EPGVKGRG-----------NIA--- 405 Clostridium ace...
WP_012458242 454 ------AddpkrylqevaTMGCRTRVFDNVN---------------G--------PKSSIGRG-----------NLS--- 490 Porphyromonas g...
WP_011077320 385 kykeviS-----------PMGCRAFLSPWYE-------KG------GmypldetdKPVYVGRF-----------NIG--- 426 Mycoplasma pene...
WP_011020131 445 ------C-----------YQCCAYQFSANPT-------DDkefddkL--------HFKDGKHF-----------SMGswm 481 Methanosarcina ...
WP_011013113 273 ------Y-----------AMCCRLNIDKREFtytfsldED------V--------EKLERQRFgglwampdvtgSVN--- 318 Pyrococcus furi...

CAF29783     476 WYTINLPRIAYEADgDDGR-----------------LFEILDEKLAIAKQALE-IKHEISK-RRLYHDNVLPFlTQeFDG 536 Methanococcus m...
AAM02114     309 YVTLNLPLLAHESR-DEDE-----------------FLEKIREYCEVAREALL-ARWRCVK-KCLEAGLYDGC-QR-WKP 366 Methanopyrus ka...
AAM25039     410 VVTINMPRIGYLSR-TKEE-----------------FFQRLERLMDIAKTSLE-IKREVLE-KMTEMGLYPYSkFYlrd- 468 Caldanaerobacte...
BAB80623     310 VVTINLPRLAYKYKnNEKE-----------------FFNALKEILIIAKDSLE-KKRKWLNdNIINKDMLPAFsTY--VG 369 Clostridium per...
WP_000940077 327 FTSINLVKLALISg-SQEA-----------------FFEALNYYLDVGIQQLL-ERFEYQC-TKRARDFRFLYsQGvWRG 386 Bacillus cereus
AAA24226     408 VISLNLPRIALEPKgDEAT-----------------FWKLLDERLVLARKALM-TRIARLE-GVKARVAPILYmEG-ACG 467 Escherichia col...
WP_011016303 431 ATSINLPRIAIKNRgDEEG-----------------FYKELDRILEICKDNCL-FRAKYLE-NTVAEMAPILWmSGaLAE 491 Fusobacterium n...
WP_006768369 428 VVSINLPRIAIAAQqSVDD-----------------FFTGLDEAIDLGVRALR-IREEVVL-SADLEQAPIMYtQGg-MG 487 Corynebacterium...
WP_010963802 406 PTTVNLPRIGILAKgDVDK-----------------FFELLHSRLEIAKESLL-HRYSVLK-KLKVKDLPFVVgQNlMKG 466 Clostridium ace...
WP_012458242 491 FTSMNLPRLAIEARhEAEEncpdgdketirsearllFLESVRRMSTLIADQLY-DRYCYQR-TALARQFPFMMgNDvWKG 568 Porphyromonas g...
WP_011077320 427 AISLHLPMILEKSRkENKD-----------------FHETLDYYLEMIRQLHI-RTYNYLG-EMRASTNPLAYcQGgFYG 487 Mycoplasma pene...
WP_011020131 482 VLSLNCPRAAYRAEyDDEK-----------------LFTELKTLMNRCVEVFK-IKRRWMN-SLIKKNRIPFAsQCpKDP 542 Methanosarcina ...
WP_011013113 319 VTTVNLPRIALKSR-DEDE-----------------FWEEYEKTLEIVRITTEwFRNRYVK---LLSMYPHMYsmi---- 373 Pyrococcus furi...

CAF29783     537 E-------QYYRYD-----S--T--TKTFGFVGLNELLKYHVG-S-ELHESPe------ALAFGVKVISHIRKYADDLKK 592 Methanococcus m...
AAM02114     367 Dg-----eYYFRYE-----H--T--TWSLGFVGLAEAIEVLTG-Y-GFWEDPs------AMRLAERVLEELNDVREEFHE 424 Methanopyrus ka...
AAM25039     469 -----vkkRFGYYW-----Qn-H--FNTIGLIGMNEALLNFMG-V-SIATEE-------GRKFALEVLDFMRHKLEQYQL 526 Caldanaerobacte...
BAB80623     370 T------------L-----Kn-H--FSTIGIVGLNEMCENFNG-N-NILTEE-------GMEFSIKVCNFIREELINFQE 420 Clostridium per...
WP_000940077 387 GeklqpedSVASIL-----Kq-G--TLSLGFIGLAECLVALTG-K-HHGEDEe------SWKLGYEIISFMRDRMDKATE 450 Bacillus cereus
AAA24226     468 Vrln-addDVSEIF-----Kn-GraSISLGYIGIHETINALFGgE-HVYDNEq------LRAKGIAIVERLRQAVDQWKE 533 Escherichia col...
WP_011016303 492 Knqk--dtIKDLIW-----GgyS--TVSIGYIGLSEVSQLLYG-K-DFSESEe------VYEKTFNILKYIADKVLEYKQ 554 Fusobacterium n...
WP_006768369 488 Npag--ktSVRDFYtgdnhKr-S--SISLGYTGIHNAMVALTG-EeHWHTVAg------HRALSHRILEHMNTRVVAVQD 555 Corynebacterium...
WP_010963802 467 SenlkpddSIEPVL-----Kq-G--TWGVGFIGLAETLVALTG-H-HHGETEe------AKELGIKIVSYIRDYLDDLKK 530 Clostridium ace...
WP_012458242 569 GaalepneEVGDVI-----Ks-G--TLGIGFIGGHNAMVAIYG-E-GHAHNKa------AWNTLYDAISVMNDVAQEYKR 632 Porphyromonas g...
WP_011077320 488 Gnlk-pneKIKPIL-----Kt-C--TASFGFTALNELQMLYNN-K-TLVEDG---------EFAIKTLEYINEKVLSFKN 547 Mycoplasma pene...
WP_011020131 543 Ntge--kgSMAVDF-----Es-L--VYTIGVVGINEMVQYHTG-Y-QIHESPv------AYKLAIRAMFEMKMHAQKLSK 604 Methanosarcina ...
WP_011013113 374 ------rdYLEEFP-----Ss-H--FNTIGILGLPEAAALYLN-SpELWKEGnrrdwieAARLMKRMVEFATEKAREWMK 438 Pyrococcus furi...

CAF29783     593 ETGLRWTVTQTPAESTAGRFAKFD--HKYYPE-----ETksV--------VNGNlndlssI---YYTNSSHVRVNADVTL 654 Methanococcus m...
AAM02114     425 RDGRRWSVVQSPAESAAERLARKY--LEKYPDa---kVR--G--------TEHR------P---YLTNSCHVPYDEDVNV 480 Methanopyrus ka...
AAM25039     527 ESSFMYNLEATPAEGASYRLAKKD--KELFPD-----II--T--------AGDDv-----P---YYTNSTQLPVDFTEDI 581 Caldanaerobacte...
BAB80623     421 ETGNLYNFEATPAESTCYRLAKKD--VEDFED-----II--V--------RGGRe----yP---YYTNSCHMPPNEVKNL 476 Clostridium per...
WP_000940077 451 EHELNFSVIATPAEGLSGKFVKKD--REEFGV-----IS--G--------ITNH------N---YYTNSFHIPVYYDIQA 504 Bacillus cereus
AAA24226     534 ETGYGFSLYSTPSENLCDRFCRLD--TAEFGV-----VP--G--------VTDK------G---YYTNSFHLDVEKKVNP 587 Escherichia col...
WP_011016303 555 KYNLGFALYGTPSESLCDRFARVD--KQEFGD-----IK--G--------ITDK------G---YYDNSFHVSSRINMSP 608 Fusobacterium n...
WP_006768369 556 QFHATVSVYATPSESLCDRFAELD--RDRFGE-----LP--G--------INDR------D---YYENSFHFPSYLHTNP 609 Corynebacterium...
WP_010963802 531 HIKLNWSCYATPAEGLSGKFIAKD--KVIFGE-----IP--G--------VTDK------D---YYTNSYHVPVGFDISI 584 Clostridium ace...
WP_012458242 633 KYHLNYSVLATPAEGLSGRFTRMD--RKRYGI-----IP--G--------VTDL------D---YYVNSFHVDVREPIGI 686 Porphyromonas g...
WP_011077320 548 EDKILYAIYATPAESLCGLQVEQF--RSKYGI-----VE--G--------VSDK------P---YVSNSFHCHVTEDITP 601 Mycoplasma pene...
WP_011020131 605 ENDMEIALARTPAETTAQRFAVSDllHWEYAEkaeftIK--GdlksakkeINEThd--lpI---YYTNGTHIPPGADVSL 677 Methanosarcina ...
WP_011013113 439 ATRVPWNVEEVPGESAQAKLALKD--MKDFPE-----LK--E--------YLDD------PenpIYSTSI-APYYGPLEL 494 Pyrococcus furi...

CAF29783     655 GEKVGIEEKFHELCNGGHIGHFWNAeAYADP-EVLMDITKKMTKTd-IGFWTYTKNLSICEKC--S-LAMSGLK----DN 725 Methanococcus m...
AAM02114     481 VERAEIEAKFHPMTLGGHITHFWLG-ERTDP-RSLMKLTVRVLRRntIGFLAITRDYSVCDRC--Q-RTYEGVV----EQ 551 Methanopyrus ka...
AAM25039     582 FTALDLQEELQTKYTGGTVFHGFIGeAISDV-ETCKALVRKIAYNyrIPYYTITPTFSICEDH--G-YISGEH-----FE 652 Caldanaerobacte...
BAB80623     477 KQLFDHQDKLQVLFTGGTVVHIYCDgAISG--EKAKHIVKTVCKKyrTPYVSISPLNRYCEEH--G-YVKERV-----EE 546 Clostridium per...
WP_000940077 505 INKIRLEGPFHALCNGGHITYIELDgAAMHNkKALKQIVQAMAENg-VGYGSINHPVDRCKCC--S-YHGVIGN-----E 575 Bacillus cereus
AAA24226     588 YDKIDFEAPYPPLANGGFICYGEYPnIQHNL-KALEDVWDYSYQH--VPYYGTNTPIDECYEC--G-FTGEFECtskgFT 661 Escherichia col...
WP_011016303 609 FEKLRLEALGHKYSAGGHISYIETDsLTKNL-DAIPDILRYAKMVg-IHYMGINQPVDKCHIC--G-YKGEFTAtkegFT 683 Fusobacterium n...
WP_006768369 610 MDKIHFEAQYMPLTPGGFMYYVEAPnLLVNP-MAFESIWDEAFDH--VGYFGINSPVDHCLVC--G-FEGEFHC----DE 679 Corynebacterium...
WP_010963802 585 KEKINIEAPYHKLCNGGHISYIELD-DYGDE-ETIMNIIKYAYENtnINYIGINFHIRYCKDC--GeYLDASD-----MK 655 Clostridium ace...
WP_012458242 687 AEKIKCEAPFHAITGGGHITYVELDgEAKKN-VSVILKIVKMMKDenIGYGSINHPVDTCKGC--G-FKGVIY-----DK 757 Porphyromonas g...
WP_011077320 602 IQKQDLEKRFWNLSNGGKIQYVKYP-INYNV-GAIKSLIKRAMKMg--FYEGVNLSLSYCGDC--G-HQELNMN-----K 669 Mycoplasma pene...
WP_011020131 678 PERIKYEHTFFPIVDGGNIMHIWLGeGKPDP-EGLQELAMHIAKNtqTGYFAFTRDMTVCIDE--G-YVAAGLL----DK 749 Methanosarcina ...
WP_011013113 495 GDRIRIEEIVQGSFTGGVMMHIFLGeE-PDP-EALAELTKKLMKTk-LVYWSYTPALTVCNSCksS-FTGLYT------S 564 Pyrococcus furi...

CAF29783     726 ----CTGCGSDh---IEKFSRITGYL-----Q--NVSNWNKAKQQELLDRKST 764 Methanococcus maripaludis S2
AAM02114     552 ----CPECGRR----CTIWSRVTGYL-----A--PVDSFVDGKKQEHKERLRH 589 Methanopyrus kandleri AV19
AAM25039     653 ----CPYCGRE----CEVYSRVVGYY-----R--PIKNWNEGKRKEFEQRKEF 690 Caldanaerobacter subterraneus subsp. tengc...
BAB80623     547 ----CPICGKK----LDLYQRITGYL-----R--KVEFFNDGKKSEFKDRNQL 584 Clostridium perfringens str. 13
WP_000940077 576 ----CPSCGNEdeanIERIRRITGYLv----G--DMSKWNSAKRSEEMDRVKH 618 Bacillus cereus
AAA24226     662 ----CPKCGNHdasrVSVTRRVCGYL-----GspDARPFNAGKQEEVKRRVKH 705 Escherichia coli str. K-12 substr. W3110
WP_011016303 684 ----CPQCGNHdsneMSVIRRVCGYL-----SqpNARPFNKGKQEEIMHRVKH 727 Fusobacterium nucleatum
WP_006768369 680 qgytCPGCSNRdetqASVTRRLCGYL-----GapMKRPVVSGRQAEINSRIKH 727 Corynebacterium efficiens
WP_010963802 656 ----CKKCGSHd---IQGISRVTGYL-----S--LDERFGVGKAAERADRISQ 694 Clostridium acetobutylicum
WP_012458242 758 ----CPVCGSDr---IARLRRITGYLt----G--SLDTWNSAKQAEEHDRVKH 797 Porphyromonas gingivalis
WP_011077320 670 ----CPQCSSTn---LTKIERMNGYLsysrvS--GDTRLNDAKMAEIAERKSM 713 Mycoplasma penetrans
WP_011020131 750 ----CPKCGSEh---VQHLSRITGYL-----Q--SVEGWNRGKRQELKDRKRY 788 Methanosarcina acetivorans
WP_011013113 565 ----CPKCGSHd---VEVWSRIIGYY-----R--PLKNWNPYRKKEFWRRKHY 603 Pyrococcus furiosus
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