Conserved Protein Domain Family
lipid_A_msbB
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TIGR02208: lipid_A_msbB 
lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase
This family consists of MsbB in E. coli and closely related proteins in other species. MsbB is homologous to HtrB (TIGR02207) and acts immediately after it in the biosynthesis of KDO-2 lipid A (also called Re LPS and Re endotoxin). These two enzymes act after creation of KDO-2 lipid IV-A by addition of the KDO sugars. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]
Links
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Statistics
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PSSM-Id: 274032
Aligned: 4 rows
Threshold Bit Score: 524.754
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
P24205    10 YIPEFDKSFRHPRYWGAWLGVAAMAGIALTPPKFRDPILARLGR--FAGRLGKSSRRRALINLSLCFPERSEAEREAIVD 87  Escherichia coli K-12
BAA89377   8 YDLSFKKTFLLPKFWPVWFGVFAIYLLAFMPVKPRDKFARFIAKklFSLKMMAKRKKVAKINLSMCFPEMDDTEQDRIIM 87  Moritella marina AT...
AAN55135   8 FDRRFQLALLHPKYWVTWLAIGLLVIFGIMPAWLRDPIAKVLAK--LVVPIAKKPIGIARANLSACFPEKSAAEIETLIN 85  Shewanella oneidens...
P44567    16 YEAHFSWSYLKPQYWGIWLGIFFLLLLAFVPFRLRDKLTGKLGI--WIGHKAKKQRTRAQTNLQYCFPHWTEQQREQVID 93  Haemophilus influen...

P24205    88 EMFATAPQAMAMMAELAIRGPEKIQPRVDWQGLEIIEEMRRNNEKVIFLVPHGWAVDIPAMLMASQGQKMAAMFHNQGNP 167 Escherichia coli K-12
BAA89377  88 VNLVTFCQTILSYAEPSARSRAYNRDRMIVHGGENLFPLLEQGKACILLVPHSFAIDFAGLHIASYGAPFCTMFNNSENE 167 Moritella marina AT...
AAN55135  86 NNVENFVLVLLSQGELLIRSKAHLRRRVNLMGFEHVKAAQAAGQPVIFIMPHVWPIDYAGLRLN-LELPMVTMAKAHKNG 164 Shewanella oneidens...
P44567    94 KMFAVVAQVMFGIGEIAIRSKKHLQKRSEFIGLEHIEQAKAEGKNIILMVPHGWAIDASGIILHTQGMPMTSMYNPHRNP 173 Haemophilus influen...

P24205   168 VFDYVWNTVRRRFGGRLHARNDGIKPFIQSVRQGYWGYYLPDQDHGPEHSEFVDFFATYKATLPAIGRLMKVCRARVVPL 247 Escherichia coli K-12
BAA89377 168 LFDWLMTRQRAMFGGTVYHRKAGLGALVKSLKSGESCYYLPDEDHGPKRSVFAPLFATQKATLPVMGKLAEKTNALVVPV 247 Moritella marina AT...
AAN55135 165 LFNWFNNRVRSSCGGHVYMREAGIRALLAELKRNNSFFYLPDEDLGPDQSVFTPFLGTVKATLPVVGRLAQAGNAQVLPV 244 Shewanella oneidens...
P44567   174 LVDWLWTITRQRFGGKMHARQNGIKPFLSHVRKGEMGYYLPDEDFGAEQSVFVDFFGTYKATLPGLNKMAKLSKAVVIPM 253 Haemophilus influen...

P24205   248 FPIYDGKTHRLTIQVRPPMDDLLEADDHTIARRMNEEVEIFVGPRPEQYTWILKLLKTRKPGEIqPY 314 Escherichia coli K-12
BAA89377 248 YAAYNESLGKFETFIRPAMQNFPSESPEQDAVMMNKEIEALIECGVDQYMWTLRLLRTRPDGKK-IY 313 Moritella marina ATCC 15381
AAN55135 245 KIGYNQVTRQFDLTVMSAIATEDMVGKENEALALNKAVEQVILAYPEQYMWFLRLLKTRPEGQAsIY 311 Shewanella oneidensis MR-1
P44567   254 FPRYNAETGKYEMEIHPAMN--LSDDPEQSARAMNEEIESFVTPAPEQYVWILQLLRTRKDGEd-LY 317 Haemophilus influenzae Rd KW20
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