Conserved Protein Domain Family
PorD_KorD

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TIGR02179: PorD_KorD 
2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family
A number of anaerobic and microaerophilic species lack pyruvate dehydrogenase and have instead a four subunit, oxygen-sensitive pyruvate oxidoreductase, with either ferredoxins or flavodoxins used as the acceptor. Several related four-subunit enzymes may exist in the same species. This model describes a subfamily of delta subunits, representing mostly pyruvate, 2-ketoisovalerate, and 2-oxoglutarate specific enzymes. The delta subunit is the smallest and resembles ferredoxins.
Statistics
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PSSM-Id: 131234
View PSSM: TIGR02179
Aligned: 14 rows
Threshold Bit Score: 100.485
Threshold Setting Gi: 446578821
Created: 8-Oct-2014
Updated: 2-Oct-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
CAF18509      15 ITEPGSSRRNLTGGWRSLRPVIHDERCIRCRVCWMYCPEG-TIKEVRgEfvvkghkyqvKYEIDYNYCKGCGICAHECPV 93  Thermoproteus t...
Q56316        15 IDKPGTAREYKTGAWRVMRPILHKEKCIDCMFCWLYCPDQaIIQEGG-I----------MKGFNYDYCKGCGLCANVCPK 83  Thermotoga mari...
P56815         8 VKKPGSTVKNKTGSWRTFKPVLDKDKCIDCDNCILFCPEG-CINR--------------EHEIDYDYCKGCGICAEKCPV 72  Methanothermoba...
O58412        28 VSLGITLVN-FTGDWRTFMPVIDESKCVKCYICWKYCPEP-AIYIKEdG----------FVAIDYDYCKGCGICANECPT 95  Pyrococcus hori...
AAL64806       4 LSKPAPASAGITGTWRTYKPVVNLSKCIDCGLCWLYCPES-VIDWEKgT----------KVRIDYDFCKGCGICADVCPV 72  Pyrobaculum aer...
AAM03487       8 TCEPGSTLANKTGGWRNFRPVYIYEKCTKCGICQIVCPDM-SVLPREdG----------FFEYNYDYCKGCGICANECPA 76  Methanosarcina ...
WP_009990062  10 VARPKIGSAGKTGLWRVEKPVISYDKCTKCRLCVLYCLEN-TIDLLEnL----------YPQIDYDYCKGCGVCAQVCPP 78  Sulfolobus solf...
WP_009990250  18 ITRPNKGAGGRTGAWRIVKPVVDYSKCIGCKACFMFCPES-TIVP-SnG----------KVRVDYEYCKGCGVCANVCPV 85  Sulfolobus solf...
WP_010879546   7 ISKSTAGSAGETGSWRILRPVVDEKKCSGCKECFYYCPEG-VIQVDV------------FARIDYRFCKGCGVCGEVCRQ 73  Archaeoglobus f...
WP_010879196  10 ISEPMQSENLKTGDWGTHYPVVDKEKCTACKTCEQYCPDL-CIEVKEfGde-------kYAVVNYNYCKGCGICASVCPF 81  Archaeoglobus f...
CAF18509      94 KAIEMVPET 102 Thermoproteus tenax
Q56316        84 QAIEMRPET 92  Thermotoga maritima MSB8
P56815        73 KAIKMEREK 81  Methanothermobacter thermautotrophicus str. Delta H
O58412        96 KAITMVREE 104 Pyrococcus horikoshii OT3
AAL64806      73 KAIDMVPEA 81  Pyrobaculum aerophilum str. IM2
AAM03487      77 DAIEMILEE 85  Methanosarcina acetivorans C2A
WP_009990062  79 KAIDMVREV 87  Sulfolobus solfataricus
WP_009990250  86 KAISMVSEQ 94  Sulfolobus solfataricus
WP_010879546  74 KAIVMVPEE 82  Archaeoglobus fulgidus
WP_010879196  82 EAIKMELKD 90  Archaeoglobus fulgidus
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