Conserved Protein Domain Family
dmsA_ynfE

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TIGR02166: dmsA_ynfE 
anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family
Members of this family include known and probable dimethyl sulfoxide reductase (DMSO reductase) A chains. In E. coli, dmsA encodes the canonical anaerobic DMSO reductase A chain. The paralog ynfE, as part of ynfFGH expressed from a multicopy plasmid, could complement a dmsABC deletion, suggesting a similar function and some overlap in specificity, although YnfE could not substitute for DmsA in a mixed complex.
Statistics
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PSSM-Id: 274006
Aligned: 7 rows
Threshold Bit Score: 1329.79
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
BAC59710       9 ITRRDALKGgSALGALALAGNALSLPFA--TKAVAKETPAKpnEKIVWSACTVNCGSRCPLRMHVVDGEIKWVET--DNT 84  Vibrio parahaem...
P77374        10 ISRRTLVKS-TAIGSLALAAGGFSLPFTl-RNAAAAVQQAR--EKVVWGACSVNCGSRCALRLHVKDNEVTWVET--DNT 83  Escherichia col...
P18775        14 VSRRGLVKT-TAIGGLAMASSALTLPFSriAHAVDSAIPTKsdEKVIWSACTVNCGSRCPLRMHVVDGEIKYVET--DNT 90  Escherichia col...
CAE10491       4 INRRQFLQWsGALGGGIAAGALLPLPSL----AQKESLSKGenEEMKWAGCAINCGSKCPLRVFVKEGKITRIET--DNT 77  Wolinella succi...
AAN54494       1 MERRSFLKMsAAMGCAATVTGCNSGSSD--VNVVPPKPPVGd-EVQTWSSCLVNCGSNCPIKVFSRDGIITRIET--DHE 75  Shewanella onei...
AAL21424      24 ISRRHFIQAsSALIALPFVSSPATAQAR-----AVTATENRpaEKVVQTCSTFDCGGKCDIRAHVSDGIVTRISTrpDNA 98  Salmonella ente...
WP_011171894  24 LSRREFIQTsAVVTGAAAIAGSIALPFSv-HAAASEHAPTAaeESIKYSACLVNCGSRCPLKVHVKNGEIIKIAN--EAI 100 Yersinia pestis
BAC59710      85 GDDVYNhNHQVRACLRGRSMRRRVYSPDRLKYPLLRVGKRGEGKFKRITWDEAFDLIGDNLKRIIKDYGNDAVYLNYGTG 164 Vibrio parahaem...
P77374        84 GSDEYG-NHQVRACLRGRSIRRRINHPDRLNYPMKRVGKRGEGKFERISWDEALDTIASSLKKTVEQYGNEAVYIQYSSG 162 Escherichia col...
P18775        91 GDDNYDgLHQVRACLRGRSMRRRVYNPDRLKYPMKRVGARGEGKFERISWEEAYDIIATNMQRLIKEYGNESIYLNYGTG 170 Escherichia col...
CAE10491      78 QEDEFG-AHQVRACVRGRSSRFKVYNPNRLLYPLKRVGKRGEGKFVRISWEEAIETIAQKLLQVKEKYGNEAIYVNYATG 156 Wolinella succi...
AAN54494      76 TNDEYG-NHQIRACARGRSLRSRTYAPDRLRTPMKRVGKRGEAKFVPISWDEAASTIASEIQRIASSYGNKSILKHYGTG 154 Shewanella onei...
AAL21424      99 LDAQMP---VMRACVRGRAYRKFVYHPDRLKYPMKRVGKRGEGKFERISWDEATTLIADNLKSITEKYGPASRYVHVGTA 175 Salmonella ente...
WP_011171894 101 YDDSTFgLHQIRPCLRGRSVRWKTYNPDRVKYPMLRVGKRGEGKFKRISWDEATTIVADNLKKTIVQYGNEAIYYQYGTG 180 Yersinia pestis
BAC59710     165 TLGGTVTKSWDPsaTLVARMMNLCGGYLNHYGDYSAANIECMSEYFYGtWVDNNSIDDVQNADLCLMFGNNPAETRMSGG 244 Vibrio parahaem...
P77374       163 IVGGNMTRSSPSa-SAVKRLMNCYGGSLNQYGSYSTAQISCAMPYTYG-SNDGNSTTDIENSKLVVMFGNNPAETRMSGG 240 Escherichia col...
P18775       171 TLGGTMTRSWPPgnTLVARLMNCCGGYLNHYGDYSSAQIAEGLNYTYGgWADGNSPSDIENSKLVVLFGNNPGETRMSGG 250 Escherichia col...
CAE10491     157 TTGGIMSRCTKG---PWARLLAQFGGHLNYYNSYSTAQITDGLKHFYG-TSAGSDIANIAHSKLVVMFGNNPVETRMSGG 232 Wolinella succi...
AAN54494     155 AYYGFASSAC------FDRVLNLNGGFLKIYGNYSWAQQNEAAAATGFaSTSGSSLTALYDSDLFLGIGYNPSEMRQSGS 228 Shewanella onei...
AAL21424     176 VSGGTFSGDK-----MARRLLNLTGGYLESYHSVSMGNTAAATPYTYGiAASGSSLDTLLDTKLVILWGHNPTETIF--- 247 Salmonella ente...
WP_011171894 181 STGANLQ-GR----NACKRMLSLIGGYLDQHGTYSTAQINTVMPYVYG-NLDETLLDEIKNSDLVVMFGHNLAETRMSGG 254 Yersinia pestis
BAC59710     245 GQIHNYVDAKNI-SHTRTICIDPRYTDTAAGREDQWIPIKHGTDAALVAAIAHVLISE---DKVDQDFLDRYCVGYDRKT 320 Vibrio parahaem...
P77374       241 GITYLLEKAREK-SNAKMIVIDPRYTDTAAGREDEWLPIRPGTDAALVAGIAWVLINE---NLVDQPFLDKYCVGYDEKT 316 Escherichia col...
P18775       251 GVTYYLEQARQK-SNARMIIIDPRYTDTGAGREDEWIPIRPGTDAALVNGLAYVMITE---NLVDQAFLDKYCVGYDEKT 326 Escherichia col...
CAE10491     233 GTGYSYKEALQK-SGAKIIHFDPRYSDSMVGACDEWIPIAPGTDAALIAAMAYVMINE---DLHDKAFLDRYCVGFSRET 308 Wolinella succi...
AAN54494     229 GEGYDFLKALEAnANLEVIMVDPRYTDSMAGKESQWLPIRPGTDAAFAEAIAYEMISSgwvDTHSKAFLDKYCVGFDKAS 308 Shewanella onei...
AAL21424     248 GHTNYFLQKMKQ-NGTRFIVVDPRYSDTVSSLADQWIPLLPTTDNALMDAMMYVIISE---NLHDRAFIARYAIGFDEDS 323 Salmonella ente...
WP_011171894 255 GQYIETVQALGQ-SRAKVIIIDPRMTDSVTTLNAEWIPIFPGTDAALVAALGHVLIKE---NLTDERFLQQYCVGWDATT 330 Yersinia pestis
BAC59710     321 LP--------ASAPE----------NGSYKDYIMGTG--PDGIEKTPEWAQPITGIPADVILKLAREIGDAKRIYITQGW 380 Vibrio parahaem...
P77374       317 LP--------ADAPK----------NGHYKAYILGEG--DDKTAKTPQWASQITGIPEDRIIKLAREIGTAKPAYICQGW 376 Escherichia col...
P18775       327 LP--------ASAPK----------NGHYKAYILGEG--PDGVAKTPEWASQITGVPADKIIKLAREIGSTKPAFISQGW 386 Escherichia col...
CAE10491     309 LP--------DSAPE----------NSSYEDYVMGRG--EDQTPKTPEWAERITKIPAQTIRRLAKEIATTKPCFIAQGW 368 Wolinella succi...
AAN54494     309 LEklvaeftaSGDPKktqylpyidvEDNYRNYILGEGkfADNGPRTPAWAAKICGISEANIKSVASKIMNAKAPFIVTGA 388 Shewanella onei...
AAL21424     324 MP--------EGVPA----------NESLVAYLTGAK---DGVVKSPEWAEKITHVPAQTIRQLARDYANTKPAALIQGW 382 Salmonella ente...
WP_011171894 331 LP--------SSAPA----------NGSYKDYILGLG--ADETEKTPEWASEITGISPTRIIQLARELGNARAAWISQGW 390 Yersinia pestis
BAC59710     381 GLQRSANGEQACKAIMMLSLLRGQVGLQGGGTGAREGNHSYPFQRFPKVP-NPISASIPMFLWTDAIFRGTEMTDLTDGI 459 Vibrio parahaem...
P77374       377 GPQRQANGELTARAIAMLPILTGNVGISGGNSGARESTYTITIERLPVLD-NPVKTSISCFSWTDAIDHGPQMTAIRDGV 455 Escherichia col...
P18775       387 GPQRHANGEIATRAISMLAILTGNVGINGGNSGAREGSYSLPFVRMPTLE-NPIQTSISMFMWTDAIERGPEMTALRDGV 465 Escherichia col...
CAE10491     369 GAQRQFNGEQSSRAIATLAAMTGNIGMLGGNNGARETSTLSIDPAWLPSK-NPIKDSISCFLWTDAILHGEEMTDIKDGV 447 Wolinella succi...
AAN54494     389 GVNRHANGEQAMRACYMLSFLTGKVGQPGVSNGALPYQGSLNRAGMSGGS-NPVKESISFFTWAEAIERGHEMTARKDGI 467 Shewanella onei...
AAL21424     383 GPQRHNCGERTARGSTLLATITGNVGIKGGWAAGYGGCANRKFAAGPEMPdNPVKAKISVMNWVQAADDASKVTP-DMGL 461 Salmonella ente...
WP_011171894 391 GIQRTANGEQASRSIMMLPLMTGNIGRAGTNTGAWGGNVKYPVPGFS-IP-NPVKTAIPCFMWTDAIFRGTEMTAKNAHV 468 Yersinia pestis
BAC59710     460 KGVEKLQN----NIKFIWNYAGNCLINQHSDINRTHDILQDEKACEMIVVIDNHMTSSAKYADIVLPDCTTSEQSDFCMD 535 Vibrio parahaem...
P77374       456 RGKDKLDV----PIKFIWNYAGNTLVNQHSDINKTHEILQDESKCEMIVVIENFMTSSAKYADILLPDLMTVEQEDIIPN 531 Escherichia col...
P18775       466 RGKDKLDV----PIKMIWNYAGNCLINQHSEINRTHEILQDDKKCELIVVIDCHMTSSAKYADILLPDCTASEQMDFALD 541 Escherichia col...
CAE10491     448 RGTQKLKS----SIKFLWNTGGNCLINQHSDSNRTAKILEDETLCEMIVDINIVRTPSNRYADIILPDATHLEQEDFIRA 523 Wolinella succi...
AAN54494     468 RGTADLDTplgaDIKAVFAINSNALINQHSDCNGTAKILEDDTKCELIVVCDCWMTASARYADILLPDTTWLESNDLVND 547 Shewanella onei...
AAL21424     462 KDADKLDS----NIRILFSLAGNYLANQNPDLHQAVRVLEDESKIQFIVASDLFMTPSAKYADLLLPETSFMERWNIGET 537 Salmonella ente...
WP_011171894 469 KNKEKLDT----NIKFLWNYASNVIANQHSDLNKTNTILQDESLCEFILVWENHMTNSAKYADLLLPDVTSVESNDLIDN 544 Yersinia pestis
BAC59710     536 GAAA--SMPYFIFASQAIQPRFECKPIYDIMSGVAKRMG---VFDEFTEGRTQEEWLQWMYAQTVKq----nNDPNLP-S 605 Vibrio parahaem...
P77374       532 DYAG--NMGYLIFLQPVTSEKFERKPIYWILSEVAKRLGp-dVYQKFTEGRTQEQWLQHLYAKMLA------KDPALP-S 601 Escherichia col...
P18775       542 ASCG--NMSYVIFNDQVIKPRFECKTIYEMTSELAKRLG---VEQQFTEGRTQEEWMRHLYAQSRE------AIPELP-T 609 Escherichia col...
CAE10491     524 SAGYssDRPYVIYCQKAIEPLGECKGVYEMCTLLAERLGgesFKAEFTEGRTQVEWLEHLWNQTRA------KKPELP-S 596 Wolinella succi...
AAN54494     548 SYASg-IMGYLVAMKAAVKPMWESISMFEMGRLIAAKMG---KEAEYTEGKDEAAWLEELYQKTRTnsantdAQPAFPnS 623 Shewanella onei...
AAL21424     538 WGTA----SYLILSEKLIEPEFERRSDYDWLREVAAKLG---IENEFSQGRDEKAWIEHIWEQTRLa----mPDENLP-D 605 Salmonella ente...
WP_011171894 545 SYASg-AYHYVTRMQNTIEPLWECRPSYDVLAEIATKLG---VGDAFTEGHTQQEWIEISYNKMRD------NNPALP-P 613 Yersinia pestis
BAC59710     606 YDEMRKQGIYKKQFDR--PHVAFEDFRRDPEANPLPSPSGKIEIYSETLAKINEEWELDE---DESITPLPEYVSTFNGW 680 Vibrio parahaem...
P77374       602 YDELKKMGIYKRKDPNg-HFVAYKAFRDDPEANPLKTPSGKIEIYSSRLAEIARTWELEK---DEVISPLPVYASTFEGW 677 Escherichia col...
P18775       610 FEEFRKQGIFKKRDPQg-HHVAYKAFREDPQANPLTTPSGKIEIYSQALADIAATWELPE---GDVIDPLPIYTPGFESY 685 Escherichia col...
CAE10491     597 FEEMRQRGLYKAPRAKk-PKVMFEGFVQNPEANPLKTPSGKIEIYSEELAQKAATWILPE---GAKITPLPEFINTKEGP 672 Wolinella succi...
AAN54494     624 YAEAQKIGVFRAFSKT--PVLALDSYING--GKAVSTPSGKVEIYSLSMAQKGKDWIFNPnvkGDYITAIPMYQPTWEGY 699 Shewanella onei...
AAL21424     606 FATLQKTRQHLFKSAP---FIAFEDNIRDPENHPFPTPSGKIEIFSKRLYDMQH---P-------EIPALSHYVPAHEGP 672 Salmonella ente...
WP_011171894 614 FSDTHNKGIIDRIFADssQYIALKDFRDDPLNNPLKTPSGKIEIYSEALATLAHEWQLTP---GDRITAVAEYCPTPEGV 690 Yersinia pestis
BAC59710     681 DSPD-RKEFPLQLTGFHYKSRAHSTYGNVDILKAAAPQELWINPIDAASRNIDNGDLVSVRSKFGEMNVRVKVTPRIMPH 759 Vibrio parahaem...
P77374       678 NSPE-RRTFPLQLFGFHYKSRTHSTYGNIDLLKAACRQEVWINPIDAQKRGIANGDMVRVFNHRGEVRLPAKVTPRILPG 756 Escherichia col...
P18775       686 QDPL-NKQYPLQLTGFHYKSRVHSTYGNVDVLKAACRQEMWINPLDAQKRGIHNGDKVRIFNDRGEVHIEAKVTPRMMPG 764 Escherichia col...
CAE10491     673 LDPA-REQFPLQFFGYHYKGTTHSSFWESAPIREINPHEAWINPMDAKARGIKTGDRVLVFNRFGKIIVTAKVTPKIMPG 751 Wolinella succi...
AAN54494     700 DDEDtKDDYPLQLMGYHTKGRTHSSYHNVPWLREAAEDAVWMNPADALGRGLRGGDKVQMWNDRGTVELPVRITPRVAPG 779 Shewanella onei...
AAL21424     673 EDAL-AKDFPLQLITWKGKNRANSTQYANPWLIEVQQQTLWINPQDAQKRGITHGDMVRIHNSRGICEIPAEVTPRIIPG 751 Salmonella ente...
WP_011171894 691 SDQEtLKSYPLQMTGFHVKGHTHSTYYNVAMLREAVPHQFWMNPIDAQARGIQQGERVEIFNSRGRIHIAVKITERVLPG 770 Yersinia pestis
BAC59710     760 VVGLGEGAWYAP--N-----AKGVDQAGSINVLTTQRPSPLAKSNPSHTNLVEVTLI 809 Vibrio parahaemolyticus RIMD 2210633
P77374       757 VSAMGQGAWHEAnmS-----GDKIDHGGCVNTLTTLRPSPLAKGNPQHTNLVEIEKI 808 Escherichia coli K-12
P18775       765 VVALGEGAWYDP--D-----AKRVDKGGCINVLTTQRPSPLAKGNPSHTNLVQVEKV 814 Escherichia coli K-12
CAE10491     752 VSVCHQGGWYKP--------KNGIDEGGCINTLTTLEPSPIAKGNPQHSILVQIRKV 800 Wolinella succinogenes
AAN54494     780 VVALGQGAWYQPdiArigrsGHPIDVGGCINTLTRYQPSPFAKGNPQHTNRVQIVKA 836 Shewanella oneidensis MR-1
AAL21424     752 VVAMQAGAWWQP--D-----ENGVDKGGCANVLSSARITALAKGNSHQTMLVEVAKA 801 Salmonella enterica subsp. enterica se...
WP_011171894 771 VIAVPQGAWRNL--N-----KDGIDVGGCINTLTTQRPSPLAKGNPQHTNLVEVKRA 820 Yersinia pestis
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