Conserved Protein Domain Family
metW
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TIGR02081: metW 
methionine biosynthesis protein MetW
This protein is found alongside MetX, of the enzyme that acylates homoserine as a first step toward methionine biosynthesis, in many species. It appears to act in methionine biosynthesis but is not fully characterized. [Amino acid biosynthesis, Aspartate family]
Links
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Statistics
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PSSM-Id: 273958
Aligned: 8 rows
Threshold Bit Score: 308.912
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
CAD78525     417 NVDEESILEIIPAGSSVLDLGCGNGQLLAAIRDRHRTPGppttehrlMGVEVAQENLLATAMRGIDVIDYDLNHGLPAFI 496 Rhodopirellula ...
CAE40427      14 RPDLARIAGWIEPGSRVLDLGCGDGALLAYLRDHRQVRG--------AGVEIDDNYVIACVQRGVEVIQQNLEDGLALFD 85  Bordetella pert...
WP_010955640   8 RADLEIIHDWIPAGSRVLDLGCGSGELLASLRDRKQVTG--------YGLEIDADNIAACVAKGVNVIEQDLDKGLGNFA 79  Pseudomonas putida
WP_002225324   4 RDDLQLIYDRIPEGSRVLDLGCGDGELLAALVEHKKCSG--------YGIEIDTNSVIAAMSRGVNVIQADLEEGLTAFN 75  Neisseria menin...
WP_027047441   8 RVDLEVVANLIPPQSRVLDVGSGDGSLLELLQDTKQVDG--------RGLELSQRGVNECVARGLSVIQGDADKDLEFYP 79  Mesorhizobium loti
WP_010918412   6 REDFREILRLVRPGSRVLDVGCGEGVLLDLLAHEKQVDA--------RGLELSASGVAACMARGLSVVQGDADLDLDHFP 77  Caulobacter vib...
WP_000188046  17 RPDFAYILNLIPDGSRVLDLGCGNGTLLYLL-KEKGIRG--------QGIEKDEDCIVECIQRGVYVHHGDIDEGLEHHQ 87  Leptospira inte...
WP_020750089  25 RADFRAIARWIEPRSTVLDLGCGDGSLLRVLQNELDVLA--------YGIEIDDAGVLAATQKGLHVIQQNLEGGLALFE 96  Ralstonia solan...

CAD78525     497 DDQFDYVILNATLQAVENVVELLNEMLRVGRHAIISFPNFAYRQLRDHYVTHgRSPkAPGEFDFDWHNTPNRRFPTIADV 576 Rhodopirellula ...
CAE40427      86 DQQFDTVVLSQTLQSMHRTEHILREMARVARHGVVSFPNFGYWPHGWSILRG-RMP-VTGQMPYQWYNTPNIHLCTLRDF 163 Bordetella pert...
WP_010955640  80 SNSFDVVIMTQALQAVEYPDRILDEMLRVGRQCIITFPNFGHWRCRWYLATKgRMP-VSDFMPYTWYNTPNIHFCTFADF 158 Pseudomonas putida
WP_002225324  76 DQSFDVIVLSQTIQAMQNTEKILRCLMRVAKQAIVSFPNFGYWRNRVQIALGgHMP-VSERMPYHWYDTPNIHWCTLKDF 154 Neisseria menin...
WP_027047441  80 DKGFDFVVLSQTLQATRNPKLVLDELLRIGNRAIVSFPNFGHWRVRLSLFVKgRMP-VTQDLPYSWYDTPNIHFCTIRDF 158 Mesorhizobium loti
WP_010918412  78 DRSFDYAVLSQTLQATRNPRHVLDELLRIADRAIVSFPNFGHWRVRWSLLSRgRMP-ETKALPLPWWSTPNIHLCTLADF 156 Caulobacter vib...
WP_000188046  88 DKRFDYVILNQTIQETRNPGEILKESLRIGKKVIVAFPNFGHWNVRWKILTTgKTP-VTDLLPYRWFNTPNLHFLSVLDF 166 Leptospira inte...
WP_020750089  97 DKSFDMVILSQTLQTIHNTAQVLREMLRVGRECIVSFPNFGYWPHRLSIFRg-RMP-VSKSLPYEWYDTPNVRVLTIRDF 174 Ralstonia solan...

CAD78525     577 RDLLGQLNVVIDEEVFWDvd--qgQRIEPDNDPNLNADTAVIAFH 619 Rhodopirellula baltica SH 1
CAE40427     164 EDLAGTLGLRILQRATFN------EGREVRVFPSWRSTLALYRFA 202 Bordetella pertussis Tohama I
WP_010955640 159 EELVHERRAKVLDRLAVDhl--hrNGWGGRLWPNLLGEIGIYRVS 201 Pseudomonas putida
WP_002225324 155 DLLCAKNNIRILERAVMT------GNRQVKHFPNLLGSLAFYRVG 193 Neisseria meningitidis
WP_027047441 159 VNLCEELGATVEKATALDaagqkiGLSMPWWFWNFFGQQAVFLLK 203 Mesorhizobium loti
WP_010918412 157 MALTQDLNLRVDASAAFAgkgaarPMNPTSAWENWRSETCLFMLS 201 Caulobacter vibrioides
WP_000188046 167 IEFCEIQKFKIEDRAYFr------DLSQVRFRPNFFSKLALFVIS 205 Leptospira interrogans
WP_020750089 175 EALAPKVGLVILDRVVLH------EGRAVHWGANWRGNVAVYRVR 213 Ralstonia solanacearum
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