Conserved Protein Domain Family
P_fruct_ADP
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TIGR02045: P_fruct_ADP 
ADP-specific phosphofructokinase
Phosphofructokinase is a key enzyme of glycolysis. The phosphate group donor for different subtypes of phosphofructokinase can be ATP, ADP, or pyrophosphate. This family consists of ADP-dependent phosphofructokinases. Members are more similar to ADP-dependent glucokinases (excluded from this family) than to other phosphofructokinases. [Energy metabolism, Glycolysis/gluconeogenesis]
Links
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Statistics
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PSSM-Id: 131100
Aligned: 4 rows
Threshold Bit Score: 714.283
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q9HH12  13 SIYTAYNTNVDAIVYLNGETVQRLIDEFGADAVRKRMEDYPREINEPLDFVARLVHALKTGKPMAVPLVN-EELHTWFDS 91  Thermococcus zilligii
P58847  26 GMFVAYNSNIDAIRHLTEEDLSKLVGFFDESDIQDRVAAYPREIAEPLDFVARLLISMREGKAAEVPAYT-ADIHEWLKE 104 Methanosarcina acetiv...
Q9V2Z7   9 GIYTAYNANVDAIVNLNAEIIQRLIEEFGPDKIKRRLEEYPREINEPLDFVARLVHALKTGKPMAVPLVN-EELHQWFDK 87  Pyrococcus furiosus D...
Q58999  18 KLFTAYNTNVDAIKYLKDEDVQKLVDEFNHKDIIERMEEYPRIIEEPLDFVARLVHSIKTGKPAEVPIKDdKKLHEWFDR 97  Methanocaldococcus ja...

Q9HH12  92 HFRYDVERMGGQAGIIANLLSNLDFREVIVYTPHLAKRQAEMFVRKPNLFYPVVEGGRLVLKHPWEAYREGDPVKVNRIF 171 Thermococcus zilligii
P58847 105 HLGFDYARMGGQAGIISNLLGRLGLKKVVAYVPWLSEEQAEYFTATGNILHPKVENGKVLLKPPGEAFKPGIGSKVNWIL 184 Methanosarcina acetiv...
Q9V2Z7  88 TFKYDTERIGGQAGIIANILVGLKVKKVIAYTPFLPKRLAELFKEG--ILYPVVEEDKLVLKPIQSAYREGDPLKVNRIF 165 Pyrococcus furiosus D...
Q58999  98 -IKYDEERMGGQAGIVSNLMATLQIDKIIVYTPFLSKKQAEMFVDYDNLLYPLVENGNLVLKKVREAYRD-DPIKINRIF 175 Methanocaldococcus ja...

Q9HH12 172 EFRAGTAFKLGDERIVVPFSGRFIVSARFES-IRIYTEPGLRPFLPEIgERVDGAILSGYQGINLRYSDGKDANYYLRKA 250 Thermococcus zilligii
P58847 185 EYSKDMNVTCAGNTFKVPRDNRLIISSRPKW-LRLDMDKQIYEQLDTL-LPVDGAMLSGYQMIKEEYEDGSTYKDYVENS 262 Methanosarcina acetiv...
Q9V2Z7 166 EFRKGTRFKLGDEVIEVPHSGRFIVSSRFESiSRIETKDELRKFLPEIgEMVDGAILSGYQGIRLQYSDGKDANYYLRRA 245 Pyrococcus furiosus D...
Q58999 176 EFKKGLKFKLNGEEITAKQSTRFIVASRPEA-LRIEIKDDVRKFLPKIgEAVDCAFLSGYQAIKEEYRDGKTAKYYFERA 254 Methanocaldococcus ja...

Q9HH12 251 KEDIMLLKRE-KDLKVHLEFASIQSRELRKKVIYNLFP-LADSVGMDEAEIAYVLSALGYDELADRIFT--YNRIEDTVL 326 Thermococcus zilligii
P58847 263 VKVIEKLKSLnPELRIHVELTSIQNRLIRKAILTEIVArHVHSLGLDTVEVANALNVLGHEELSYSVIRkgENGIMSLYQ 342 Methanosarcina acetiv...
Q9V2Z7 246 KEDIRLLKKN-KDIKIHVEFASIQDRRLRKKVVNNIFP-MVDSVGMDEAEIAYILSVLGYSDLADRIFM--YNRIEDAIL 321 Pyrococcus furiosus D...
Q58999 255 EEDIKLLKKN-KNIKTHLEFASISNIEIRKMVVDYILS-NVESVGMDETEIANVLHILGYDELSNNILK--DSFIEDVIE 330 Methanocaldococcus ja...

Q9HH12 327 GGKILLDEMN-LDVLQIHTIYYIMYITHADNPLSEEELRRSLELATTLAASRASLGDITSPDQIEIGLRVPYNER--GEY 403 Thermococcus zilligii
P58847 343 GAVQLMKDLD-LERVHVHSLGFYICILAKGHPLTLKEHRDSLLFSSVLAAAQALNGNIENLAEAEAGLEVPVSSIglEDL 421 Methanosarcina acetiv...
Q9V2Z7 322 GGMIILDELN-FEILQVHTIYYLMYITHRDNPLSEEELMRSLDFGTILAATRASLGDINDPRDVKVGMSVPYNER--SEY 398 Pyrococcus furiosus D...
Q58999 331 GAKILLDKFKnLEVVQVHTIYYILFVCRADNPLSKEELEECLEFSTILASTKAKLGNIRAIDDLHEGLKIPHNKY--GDL 408 Methanocaldococcus ja...

Q9HH12 404 VKLRFEEAKRKLRT-----------KEYKLVIIPTRLVQNPVSTVGLGDTISTGAFASYLAMLKEK 458 Thermococcus zilligii
P58847 422 ENFQLYCTGRKLCTpdefeygyvygSEHDAILIPSKVVERPKATVGIGDTISAGAFVAMLAKIKQK 487 Methanosarcina acetivorans C2A
Q9V2Z7 399 IKLRFEEAKRKLRL-----------KEYKVVIVPTRLVPNPVSTVGLGDTISTGTFLSYLSLLRRH 453 Pyrococcus furiosus DSM 3638
Q58999 409 LK----EIAEKFND-----------NNYKIALSPSRYVEKPKSTVGLGDTISSGAFVYYVSLLNKK 459 Methanocaldococcus jannaschii DSM 2661
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