3RKO


Conserved Protein Domain Family
NDH_I_L
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TIGR01974: NDH_I_L 
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proton-translocating NADH-quinone oxidoreductase, chain L
This model describes the 12th (based on E. coli) structural gene, L, of bacterial NADH dehydrogenase I, as well as chain 5 of the corresponding mitochondrial complex I and subunit 5 (or F) of the chloroplast NAD(P)H-plastoquinone dehydrogenase complex. [Energy metabolism, Electron transport]
Links
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Statistics
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PSSM-Id: 273905
Aligned: 17 rows
Threshold Bit Score: 685.167
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3RKO_L         2 NMLALTIILPLIGFVLLAFSRGRWSeNVSAIVGVGSVGLAALVTAFIGVDFFANg-E-QTYSQPLWTWMSVGDFNIGFNL 79  Escherichia col...
Q9XAR5         3 NLIALLVAAPLLGAVVLLCGGRRLD-RVGHWIGTLLAAVSFVLGVVLFADLLGSgaEdRTLTQHLFSWIPVEGFQADVAF 81  Streptomyces co...
Q9ZCG1         5 NLAIMIIILPLVSSIINGLFLNIIDkKLAKIIAISFLSLSALFSLVIFCDVTLVg---KIIHIKLLPWIEFKNLQVNWSI 81  Rickettsia prow...
Q9PMA7         5 ALIS--LFSPFVAFLFASCFALSEKkQFVGIICSLLVALS---AFCSLYLLFCN----EAFNVSLFEWFAG----VNFGF 71  Campylobacter j...
P33607         2 NMLALTIILPLIGFVLLAFSRGRWSeNVSAIVGVGSVGLAALVTAFIGVDFFANgeQ--TYSQPLWTWMSVGDFNIGFNL 79  Escherichia col...
P57262         2 SIIFFIILFPLIGFLFLSTIQDFIFkRYTLNIGIFSIFISFFITCFYGVSILKNnnQ--VFTQILWKWLSINEFKIDFGF 79  Buchnera aphidi...
WP_010962954   2 DILKLIVFLPLFGSLFAALFRK------SQLVTTAGIGISAVLSWYVFLTFSEN------YHLSLFPLFSLSILKVNWAI 69  Wolbachia endos...
WP_000233076   9 vLIPTLVALPLIGFLVSGIFGKWLk-GFTGIFSTATVFVSFALALLSFVDRFHPmrNgIPKIVTLFPWITTGGLNVSLAY 87  Leptospira inte...
O86350         8 HYTWLLVALPLAGAAILLFGGRRTD-AWGHLLGCAAALAAFGVGAMLLADMLGRdgLeRAIHQQVFTWIPAGGLQVDFGL 86  Mycobacterium t...
WP_001200192   5 SLLSVVLFLPLIGAIYAGLFGAKAKaLHVGVFNSLCVLVSFIGAVVLFIQAWHH----QSYEKYLFDWIVVGNFKVGFSL 80  Helicobacter py...

3RKO_L        80 VLDGLSLTMLSVVTGVGFLIHMYASWYMRGEEGYSRFFAYTNLFIASMVVLVLADNLLLMYLGWEGVGLCSYLLIGFYYT 159 Escherichia col...
Q9XAR5        82 RLDQLSMTFVLLITGVGSLIHLYSVAYMEHDERRRRFFGYLNLFLAAMLILVLADNYLLLYVGWEGVGLASYLLIGFWQH 161 Streptomyces co...
Q9ZCG1        82 YIDQLTSIMFIAVTFVSSVVHIYSLGYMAEDKGIIRFLSFLSLFTFFMLMLVSADNFLQLFCGWEGVGVCSYLLIGFWHS 161 Rickettsia prow...
Q9PMA7        72 DIDAISLTMMSVVGIVATCVHFYSIFYMAHDEGFNKFFAYLGLFVFSMLFLVMSDNFLGLFVGWEGVGLCSWLLIGFWYK 151 Campylobacter j...
P33607        80 VLDGLSLTMLSVVTGVGFLIHMYASWYMRGEEGYSRFFAYTNLFIASMVVLVLADNLLLMYLGWEGVGLCSYLLIGFYYT 159 Escherichia col...
P57262        80 FLDGLSLSMLFVITGVGLLIHIFSSWYMRYKEGQSRFFAYTNLFIASMSVLVLADNFLFMYLGWEGVSVCSYLLIGFYYT 159 Buchnera aphidi...
WP_010962954  70 SVDALSSLMLIVITTVSLVVHLYSIGYMEHDKGKSRFFSYLSLFTFCMIVLVVSDNFVQLFFGWEGVGLCSYLLIGFWFQ 149 Wolbachia endos...
WP_000233076  88 QVDQLSLYMVLIITGIGSLIHLYSIGYMKGDPGFARYFAYLNLFIFSMLNLVLAENLILLFLGWEGVGLCSYLLIGFDYH 167 Leptospira inte...
O86350        87 QIDQLSMCFVLLISGVGSLIHIYSVGYMAEDPDRRRFFGYLNLFLASMLLLVVADNYVLLYVGWEGVGLASYLLIGFWYH 166 Mycobacterium t...
WP_001200192  81 MLDNINAVMIVVVTLVSFLVHVYSIGYMEHDAGFNRYFSYLSGFVFSMLVLVLSDNFLGLFIGWEGVGLCSYLLIGFWYH 160 Helicobacter py...

3RKO_L       160 DPKNGAAAMKAFVVTRVGDVFLAFALFILYNELGTLNFREMVE--L----------APAHFadgNNMLMWATLMLLGGAV 227 Escherichia col...
Q9XAR5       162 KPSAATAAKKAFLVNRVGDMGLSIGIMLMFLWFGTFAFGPVLG--Ghge----aglAAGAD---EGKLTAIALMLLLAAC 232 Streptomyces co...
Q9ZCG1       162 KESANKAAIKAFITNRVSDFAFILGIITIIVYYGSANYKDVFS--Saklls---ntkiFVH---FSILDIICLLLFIGCM 233 Rickettsia prow...
Q9PMA7       152 NDTYSFAANEAFIMNRIADLGMLLGIFWLYLQAGTLKYDEVFS--Maqsl-------------dhnALILIATCLFIGAM 216 Campylobacter j...
P33607       160 DPKNGAAAMKAFVVTRVGDVFLAFALFILYNELGTLNFREMVE--Lapah------fadGN---N-MLMWATLMLLGGAV 227 Escherichia col...
P57262       160 ELKNNLCAFKAFILTRVSDVFLMIGMFLIYREFNSFNFQEIKF--Lssfl------nveNF---Y-YLDYITLFLLLGVI 227 Buchnera aphidi...
WP_010962954 150 KYSANNAAIKAFVVNRVGDFALLIGIFLIYYTFHSLNFTEVFD--TtdllgtqnirAFCCE---FKVTHIICILLFIGCM 224 Wolbachia endos...
WP_000233076 168 KETAANAGMKAFIVNRIGDLGMLLGIAFVFWYTGSVSFTVIEEaiL----------EIPSF---RYILPLAAACFFIGAI 234 Leptospira inte...
O86350       167 KPSAATAAKKAFVMNRVGDAGLAVGMFLTFSTFGTLSYAGVFA--G----------VPAAS---RAVLTAIGLLMLLGAC 231 Mycobacterium t...
WP_001200192 161 KTSANNASIEAFVMNRITDLGMLMGIILIFWNFGTLQYKEVFS--M----------LNNTD---YSMLFYISVFLFIGAM 225 Helicobacter py...

3RKO_L       228 GKSAQLPLQTWLADAMAGPTPVSALIHAATMVTAGVYLIARTHGLFLMTPEVLHLVGIVGAVTLLLAGFAALVQTDIKRV 307 Escherichia col...
Q9XAR5       233 GKSAQVPLQSWLGDAMEGPTPVSALIHAATMVTAGVYLIVRSGAIFNGAPDAQLVVTIVGAVTLLFGAIVGCAKDDIKKA 312 Streptomyces co...
Q9ZCG1       234 GKSAQIGLHVWLPDAMEGPTPVSALIHAATMVTAGVFLVARCSYLFEYSPIVLQFITIIGGITCLFAASIAIMQSDIKKI 313 Rickettsia prow...
Q9PMA7       217 GKSAQFPFHTWLADAMAGPTPVSALIHAATMVTAGVYLVIRASTLYDLVPEVSYIIALLGAFVAIFAASMALVVRDLKRI 296 Campylobacter j...
P33607       228 GKSAQLPLQTWLADAMAGPTPVSALIHAATMVTAGVYLIARTHGLFLMTPEVLHLVGIVGAVTLLLAGFAALVQTDIKRV 307 Escherichia col...
P57262       228 GKSAQLPLQTWLSDAMVGPTPVSALIHAATMVTAGVYLIARTHFLFLLTPGILYLVGLIGTLTILVSSISALVQKDIKRI 307 Buchnera aphidi...
WP_010962954 225 GKSAQLGLHVWLPDAMEGPTPVSALIHAATMVTAGIFLVAKCSPLFELSNVARELIVIVGALTAFFAATVAITQNDIKKI 304 Wolbachia endos...
WP_000233076 235 GKSAQLPLHVWLPDAMAGPTPVSALIHAATMVTAGIFLIARLNPIFLSAPQVGHWIVVIGSITAFFAATVGLFQNDIKKV 314 Leptospira inte...
O86350       232 AKSAQVPLQAWLGDAMEGPTPVSALIHAATMVTAGVYLIVRSGPLYNLAPTAQLAVVIVGAVTLLFGAIIGCAKDDIKRA 311 Mycobacterium t...
WP_001200192 226 GKSAQFPMHTWLANAMEGPTPVSALIHAATMVTAGVYLVIRANPLYSAVFEVGYFIACLGAFVALFGASMALVNKDLKRI 305 Helicobacter py...

3RKO_L       308 LAYSTMSQIGYMFLALGVQ--AWDAAIFHLMTHAFFKALLFLASGSVILACHHEQNIFKMGGLRKSIPLVYLCFLVGGAA 385 Escherichia col...
Q9XAR5       313 LAGSTMSQIGYMVLAAGLGpiGYVFAIMHLVTHGFFKAGLFLGAGSVMHGMNDEVDMRRYGGLRKYMPVTFVTFGLGYLA 392 Streptomyces co...
Q9ZCG1       314 IAYSTCSQLGYMFMACGVS--SYNSAIFHLVTHAFFKALLFLSAGNVIHAVN-EHNIFKMGGLINKMPITYGNFLIGSLA 390 Rickettsia prow...
Q9PMA7       297 IAYSTLSQLGYMFVAAGLG--AYGIALFHLATHAFFKSLLFLGAGNVMHAMNDKLDIKKMGGLFKPLKITAILMCIGSLA 374 Campylobacter j...
P33607       308 LAYSTMSQIGYMFLALGVQ--AWDAAIFHLMTHAFFKALLFLASGSVILACHHEQNIFKMGGLRKSIPLVYLCFLVGGAA 385 Escherichia col...
P57262       308 LAYSTMSQIGYMFLALGVK--AWSAAITHLIMHAIFKALLFLSAGSLIKSCKNEKNIFKMGGLRKQLPFLYISFIVGGAS 385 Buchnera aphidi...
WP_010962954 305 IAYSTCSQLGYMFMACGLS--AYNVAIFHLMTHAFFKALLFLGAGNVIHAMHHEQNIQKMGNCWKKIPCTYALMWIGSLA 382 Wolbachia endos...
WP_000233076 315 LAYSTVSQLGYMFVAMGAG--AYVAGLFHLMTHAFFKALLFLGSGSVIHALHHEQDLRNMGGLKKQMKITWITFLIGSLA 392 Leptospira inte...
O86350       312 LAASTISQIGYMVLAAGLGpaGYAFAIMHLLTHGFFKAGLFLGSGAVIHAMHEEQDMRRYGGLRAALPVTFATFGLAYLA 391 Mycobacterium t...
WP_001200192 306 VAYSTLSQLGYMFVAAGLG--AYAIALFHLFTHAFFKSLLFLGSGNVMHAMEDNLDITKMGALYKPMRITAVFMIIGSVA 383 Helicobacter py...

3RKO_L       386 LSA-LPlVTAGFFSKDEILAGAMANG-H--INLMVAGLVGAFMTSLYTFRMIFIVFHGKEQIHAH--------------- 446 Escherichia col...
Q9XAR5       393 IIG-FP-GLSGFFSKDKIIEAAFAKGgTegWILGACALLGAAITAYYMTRVMLMTFFGEERWRNAptpspakpdvepaae 470 Streptomyces co...
Q9ZCG1       391 LIGiYP--LSGFYSKDLILEATYSSg----SFMFIFGIITAILTAIYSMKIIILVFHGKTKLEKDv-------------- 450 Rickettsia prow...
Q9PMA7       375 LAGiYP--FAGFFSKDLILGYSFIS--Fh-HGIFLVLLIAAFLTAFYSFRLLMLVFFTPARHDEhp-------------- 435 Campylobacter j...
P33607       386 LSA-LPlVTAGFFSKDEILAGAMANGh---INLMVAGLVGAFMTSLYTFRMIFIVFHGKEQIHAHa-------------- 447 Escherichia col...
P57262       386 LVS-FPlITAGFYSKGNILFSVLKSGc---IDFFIIGLFCSFLTAIYTFRMIFVIFHGKNIHTADs-------------- 447 Buchnera aphidi...
WP_010962954 383 LSG-IF-PFAGFYSKDLIIEHAYS---Td-SFAFVISLVVAFFTAFYSWRLLLLVFHSQKQ--SK--------------- 439 Wolbachia endos...
WP_000233076 393 ISG-IP-PFSGFFSKDLILEKAYTYG-T---LFYGLGIITALLTAFYMFRMTYLTFYGESRVSSEk-------------- 452 Leptospira inte...
O86350       392 IIG-VP-PFAGFFSKDAIIEAALGAGgIrgSLLGGAALLGAGVTAFYMTRVMLMTFFGEKRWTPG--------------- 454 Mycobacterium t...
WP_001200192 384 LCG-IY-PFAGYFSKDKILEVAFGM--Hh-HILWFALLIGAIFTAFYSFRLIMLVFFAPKQHEINhp------------- 445 Helicobacter py...

3RKO_L       447 -------A---VKGVTHSLPLIVLLILSTFVGALIVp------------pLQGVLPQTTELA----HGSMLTLEITSG-- 498 Escherichia col...
Q9XAR5       471 trgtyepPhphESPGLMTIPMIVLAVGSVGAGAFFS--------------IGDRFMHWLEPItg-hSHGDSPISAGAVtg 535 Streptomyces co...
Q9ZCG1       451 ------fKhahEPTKIMNNPLILLVAGSFFSGMIGYyllsmd---kpngyFHESLFNLHIYKl--lINHHPLYIKLLPm- 518 Rickettsia prow...
Q9PMA7       436 ----------hEASKIALLAMSPLMVLAIIAGFFEHsff---------eyLSTKLVFIDAQN--------QIVMICAS-- 486 Campylobacter j...
P33607       448 -----------VKGVTHSLPLIVLLILSTFVGALIVp------------pLQGVLPQTTELAh----gSMLTLEITSG-- 498 Escherichia col...
P57262       448 -----------STNLQHNIPLFVLLLLSTVFGSYISp------------pLSDVFPLSYTPId-----hKFAFEIICS-- 497 Buchnera aphidi...
WP_010962954 440 -------InihEAPKIMLIPLLILAFGSVFSGIWGAnilni----tsnafWKSSLVMIDEH------GVHNFFIKLLPt- 501 Wolbachia endos...
WP_000233076 453 ------aShlhESPLVMTIPLIILSIGATVTGFLEVphlfyggvriltsyFGPVFIRGIEISerivKQPLDAREVGTTtt 526 Leptospira inte...
O86350       455 -------AhphEAPAVMTWPMILLAVGSVFSGGLLA--------------VGGTLRHWLQPVvgshEEATHALPTWVAtt 513 Mycobacterium t...
WP_001200192 446 ----------hEAQNFMLLSMLPLGVLAVIAGFFEEpff---------hfISQVIPSVGEYLv-----PLALLISITT-- 499 Helicobacter py...

3RKO_L       499 ----------VVAVVGILLAAWlw---lGKRTLVTSIAn-----------SAPGRLLstwwY----NAWGFDWLYDKVFV 550 Escherichia col...
Q9XAR5       536 a-------tvACMVIGVAVAWAq----yGRRPVPAVAPr----------gSLLTRAA----R----RDLLQDDFNHVVLV 586 Streptomyces co...
Q9ZCG1       519 ----------AVGIVGIIIGIClykgslSYQTLTNESDqrekdwipkskcKMILVFI----SnvlrNKYYFDEIYNHLII 584 Rickettsia prow...
Q9PMA7       487 ----------VAAILGAILAIFayk----nsWFKESIEe-----------NKIHKLL----S----NDYFIPQFYHQFIV 533 Campylobacter j...
P33607       499 ----------VVAVVGILLAAWlw---lgKRTLVTSIAn-----------SAPGRLL----GtwwyNAWGFDWLYDKVFV 550 Escherichia col...
P57262       498 ----------ILSLSGIYLSYYiw---ikNLYVLDKIFq-----------FKFMRYL----YyfflKGWGFNWFYKISFV 549 Buchnera aphidi...
WP_010962954 502 ----------LASLSGIALAYLi----yQYQVIRQik------------sKFLLKFL----Q----NKWYFDEVYEFVII 547 Wolbachia endos...
WP_000233076 527 velsliavsiAVAISGIFIARMi----fLNGKKVPDSEes---------hTGIKRIL----T----KKYYVDEFYHNFIV 585 Leptospira inte...
O86350       514 l-------alGVVAVGIAVAYRm----yGTAPIPRVAPvr---------vSALTAAA----R----ADLYGDAFNEEVFM 565 Mycobacterium t...
WP_001200192 500 ----------IVVLLSIAYAIFk----yKN-GITSKKEg-----------GFLYKLL----L----NQYYIPQLYQG-IA 544 Helicobacter py...

3RKO_L       551 KPFLGIAWLLKrDPLNSMMNIP-----AVLSRFAGKGLLLSENGYLRWYVASMSIG 601 Escherichia coli BL21(DE3)
Q9XAR5       587 RGGEHLTRSLV-YVDHTVVDGVvn-gtAASVGGLSGRMRRLQNGFARSYAVSMFGG 640 Streptomyces coelicolor A3(2)
Q9ZCG1       585 KPIHCLTYLFYfG-DQKIIDRFgpngfARVINYFCAVTCKIQTGYIFNYTLYIVSF 639 Rickettsia prowazekii str. Madrid E
Q9PMA7       534 SKYESLCAILKh-CDLYIFDRIve-kiALYSQNISQKMIMPN--SLNLMLRFLVAA 585 Campylobacter jejuni subsp. jejuni NCTC...
P33607       551 KPFLGIAWLLKrDPLNSMMNIP-----AVLSRFAGKGLLLSENGYLRWYVASMSIG 601 Escherichia coli K-12
P57262       550 YFYLYISKRLSaDPLNKIINYF-----LKVTQIFNFYLLKTSNGYVRWYVASMILG 600 Buchnera aphidicola str. APS (Acyrthosi...
WP_010962954 548 APIRFISRLLWkF-DVKAIDSFgpngvVRLVNECSKSSIKLQTGYIFDYAFIMFVT 602 Wolbachia endosymbiont of Drosophila me...
WP_000233076 586 EPILLLGKFLAdHVERNFLDLMlr-gtGRVAVAISLVLRRAQTGIVVDYAILIVLG 640 Leptospira interrogans
O86350       566 RPGAQLTNAVV-AVDDAGVDGSvn-alATLVSQTSNRLRQMQTGFARNYALSMLVG 619 Mycobacterium tuberculosis
WP_001200192 545 KVFSAIASFLHqVVELKIIDAIvd-aiGRSVFVIGRVFRISQDGNLTSMLRFMVAG 599 Helicobacter pylori
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