Conserved Protein Domain Family
cas_CXXC_CXXC

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TIGR01908: cas_CXXC_CXXC 
CRISPR-associated protein Cas8b1/Cst1, subtype I-B/TNEAP
CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This (revised) model describes a conserved region from an otherwise highly divergent protein found in the Tneap subtype of CRISPR/Cas regions. This Cys-rich region features two motifs of CXXC.
Statistics
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PSSM-Id: 162595
View PSSM: TIGR01908
Aligned: 7 rows
Threshold Bit Score: 315.972
Threshold Setting Gi: 14916755
Created: 8-Oct-2014
Updated: 2-Oct-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
AAL81247     130 EDPNAPICEICGRRHs-----RSKPVYRSEFPLIG--SGGVPNYFPSGKEGANICSHCLFLVqflpLILYRLRRLLLIHT 202 Pyrococcus furi...
AAM07023      95 DVLTSGNCVTCGRRN------VEQIRTKTEIPLIG--SGGMINYFPSGQPGADYCPACTFAVqfspLVSYSCVKLLLLHS 166 Methanosarcina ...
O66695       176 EDKNAPLCFFCRERHtyvykgKYRVFGAEHFTPLSasEDTLPNLFWNGRNKMYLCPYCEFYL-------FFAAFGFTKVG 248 Aquifex aeolicu...
WP_010885339  93 EDPSTPLCEICGRRHs-----RSKPVYRSEFPLIG--SGGVPNYFPSGKDGANICSHCLFLVqfmpLILYRLPRLLLIHT 165 Pyrococcus hori...
WP_012675210 219 KRDKTYKCINCIDRQa-----KKDTIFDTGISKFYglNPDSVNFVWNFKPKLPLCEICEIIY----FSYFAGLIPVNKNG 289 Persephonella m...
WP_012673661 222 kkdkkflCISCMERKa-----KKDTIFDTGISKFYglNPDVINFSWNFNPKIPLCEICEIIY----FSYFAGLTLIQKDG 292 Sulfurihydrogen...
WP_012548304 200 KIKRSILCINCGERYa-----KKDTSFDTGISPFTgvNTDALNFFWNFNAKLPLCEICELIY----FCTFRGFTESVLEN 270 Dictyoglomus th...
AAL81247     203 YppELMLELHREALKDVRLTKLVSS-----GRGYQRPENFLFTLLTEVTIKT--EREELWENAS--ITLYYFTNPNRErP 273 Pyrococcus furi...
AAM07023     167 DseKVMHYWADKAIKDIRRQISVNSysgcyDEGYKNPVNALFHIIEDIILQY--EENWITENPS--INMYHFTNYIQG-P 241 Methanosarcina ...
O66695       249 NnrFLFVYIPDDLDSLISINSQLKS-------KEKVEKNILGELFRVVKFLRnvETQKARWILEniYFVEIEKVS-EAtA 320 Aquifex aeolicu...
WP_010885339 166 YppELMLELHREALNDVLLTRLVSS-----GRGYKRPENFLFTLLTEVSLKT--EDEKLWENAS--ITLYYFTNPNRGrP 236 Pyrococcus hori...
WP_012675210 290 KtvFYYVNSDTSLESLLKENLLLER-----KLTKEISENPFIEFFTELVLMS--EEERARYTLQntVIIELDLNN-ETmP 361 Persephonella m...
WP_012673661 293 KraFYFVNSDTSIIDLVSNNRLLNG-----VLKPDLTENILLNFFTQLVLES--SYQKAYFTVQniSVLELDLNN-EImP 364 Sulfurihydrogen...
WP_012548304 271 K--YFFVNSDTSVIDLYKKNLLLQE-----KLKKNLTENIFVEFFSELLLRE--EYEKSTHRLQgiAFIEIDLTNKDVlP 341 Dictyoglomus th...
AAL81247     274 KMMIIHVPSSVTRFVAHAaRHDL-SGWKRIVAMGWK--------------KGSD-EKSSPNEVYLKLLNgeSILPYFINV 337 Pyrococcus furi...
AAM07023     242 DLDIYRVPTPVFRFLAFVkQMDQfSEWKKIVRKGYFhqd---------kiKEGDdYKNRGNSVYINLLKgnSIVKYFIDN 312 Methanosarcina ...
O66695       321 NIYSFSISPRLAKVLKNYiDKYPpNFESv---------------------FPKFvEYVYSGRSLYEFLFkiLSGFFFPKR 379 Aquifex aeolicu...
WP_010885339 237 EMTIIHVPSTVTRFVAHAaRHDR-AGWERIVAMGWR--------------KGREnEKVHSNEVYQKLLSgeSILPYFINM 301 Pyrococcus hori...
WP_012675210 362 KIYSFNISREKAEFLVNN--KENfQKLSKVFYKIKNdsf---------svLPEViEKTLNNSLNFKYLN--RLIKLHLKN 428 Persephonella m...
WP_012673661 365 KVYSFNLSRKKAEFLKESkTKENlKQLSKDYYKINRkkgel-----kiyiLPEViSLILENKLYFNYLNk--ILRMFIAY 437 Sulfurihydrogen...
WP_012548304 342 KVFSFNISRAKAEFLKEHaEK-NfKNLINIRYSIKRysikdsikeiiknvTLEFlEKILSNTLSYGYLS--FLEYLLLES 418 Dictyoglomus th...
AAL81247     338 AKRRTNASWDLLSFYCTEVLGLDEKALEFIK-----EVGDRIVETLKE------LPDnklSARVRELERAEKLYQFEAFF 406 Pyrococcus furi...
AAM07023     313 KTRQVYGDWELLGYYLTEVRNMGGKRLDTLK-----KVGDSLSEYIKD------TQN---IKRLNQLEMASNFATFRNQL 378 Methanosarcina ...
O66695       380 YQNPKGYDADLIKKGMSFKEFLPKKLLYFIKfqeelIMGESFEKQINFayreglNLKkmyEKELGKEKAKDRIKTLSYRI 459 Aquifex aeolicu...
WP_010885339 302 TERKPNASWNLLFFYCTEVLGLNKEALEFIK-----EVGDRIVETLKE------LPDnklSARVRELERSEKLYQFEAFF 370 Pyrococcus hori...
WP_012675210 429 ANDSSYYATNITSYQLQLLNLLTKEFLQKV------ILGGTDMGIDENnlwsiyYQGidlAKKLRESNAENKIQSIAYKL 502 Persephonella m...
WP_012673661 438 QNGSERYETNISPYKIQILNLVVSE---FIK-----NIGGKTMSVSEKeiwviyQEGkklANILSEKKAENKIKSIAYKL 509 Sulfurihydrogen...
WP_012548304 419 IKGNKDVKTYYSPIHLNILNIIIEDYIQKFKk---yERGEKMSSKNEEqlwfmfKKGeeiANKLISENSENKIPSLTYKL 495 Dictyoglomus th...
AAL81247     407 VNLEKLRQRLGLKDPLLTF 425 Pyrococcus furiosus DSM 3638
AAM07023     379 RLIEKDRIKLGDQDSIFTL 397 Methanosarcina acetivorans C2A
O66695       460 LEAVRRKDLDAFEQNLIRA 478 Aquifex aeolicus VF5
WP_010885339 371 VNLEKLRQRLGLKGSLMTF 389 Pyrococcus horikoshii
WP_012675210 503 LNALRIGDTNQFMDVLIRT 521 Persephonella marina
WP_012673661 510 LNSLRIGNSQQFMDILLRV 528 Sulfurihydrogenibium azorense
WP_012548304 496 LSCLRTEDVHSFMNIILRL 514 Dictyoglomus thermophilum
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