4L6U


Conserved Protein Domain Family
cas_TM1795_cmr1
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TIGR01894: cas_TM1795_cmr1 
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CRISPR type III-B/RAMP module RAMP protein Cmr1
CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model represents the region of stongest conservation, the N-terminal half, of one such family, represented by TM1795 from Thermotoga maritima. This protein is the first of a set of six genes, mostly from the RAMP superfamily, that we designated the CRISPR-associated RAMP module.
Links
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Statistics
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PSSM-Id: 273859
Aligned: 12 rows
Threshold Bit Score: 102.479
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
4L6U_A        10 LEAITPVFMRGANQ---S------K-A--------EIRAASIKGLMRWWFRAL----S---G---S---YFGNDVEGLRR 58  Archaeoglobus f...
WP_011012270   8 IESITSTHLLEVLT---R------EyP--------EVRSPSIKGAMRWWFRAL----A---G---S---YFGDDAQKLKE 57  Pyrococcus furi...
WP_010896508  35 ISIITHMFGGGTKAgqvD------KeI--------PVRSTSIRGNLRFWWRAT----R---G---A---MY-PNVKSLKE 86  Bacillus halodu...
WP_009990109  25 fvgVTPWWGRDHRG---Y------TsD--------HVDEDGIVGKLRWFLRTV----Y---N---R---FCVKNLNSYDE 74  Sulfolobus solf...
WP_011026630   8 LQIVTPIIMSGARK---N------L-L--------ELREQSINGILRWWFRFY----G---S---L---KY-QSLQELRK 55  Caldanaerobacte...
WP_010880201  11 FEIITPVVMAGTYK---D------E-P--------ELRIPSIKGMLRWWFRFF----Y---A---S---HN-QSIDKLRE 58  Aquifex aeolicus
ZP_00075987    9 IETLTPIWTGGVNG---S------P-D--------TVRETGIIGSMRWWYEAI----VrgiG---K---YACNPLSDSKC 60  Methanosarcina ...
WP_011011465  17 LEAITPLFMRGADA---R------S-P--------EFSSASVKGVMRWWFRAL----A---G---G---YFGNNIEALKE 65  Pyrococcus furi...
WP_004082342  15 CKVVTPMFSRGAAE---P------KwEngnrvypfELRPQSIKGVLRFWFRAIaptvI---D---I---YSLEGLENLSK 76  Thermotoga
WP_009992994  10 LKAIYPLTGGYNRH---Sin--efYeE--------NVRPTEIKGLWRWWNRVL----F---NtvsY---VKEGKLYTYDS 66  Sulfolobus solf...
WP_010875967  16 LQILNEIFTGGPER---R------S-E--------VIRDTGLIGSLRWWYEAL----IrgvG---G---TACDPSQGPPC 67  Methanothermoba...
WP_010980048  10 AKALYPIVGGYNQY---PvslkvgYeE--------PIRSTEIKGLWKWWTRIL----I---E---SaieRKRHGVTKYND 68  Sulfolobus toko...

4L6U_A        59 VEe----------------YVFGSTKRESRVVVEVVKEHV------------------------EErfcPL---P----- 90  Archaeoglobus f...
WP_011012270  58 IEn----------------QVFGSTKERSRVKISVTPLSS------------------------PK---RL---Nlkefk 91  Pyrococcus furi...
WP_010896508  87 AEa----------------KIFGDTNRPSAVKISVSETGD------------------------AK---WA---Pilerk 120 Bacillus halodu...
WP_009990109  75 ADsy-------------vfEYLGSGNRKSLYIFKVSDSRS------------------------IP---NK---K----- 106 Sulfolobus solf...
WP_011026630  56 REs----------------EIFGSTTKAKRFYIKILQEPQ------------------------S-----R---G----- 82  Caldanaerobacte...
WP_010880201  59 HEn----------------EIFGSTEKACQFYMHLKY---------------------------SQ---KL---T----- 84  Aquifex aeolicus
ZP_00075987   61 MLdgkekendrnnklcpacYLFGCGGWKRRFRLEIEDFGV------------------------KE---PF---H----- 105 Methanosarcina ...
WP_011011465  66 VEe----------------KIFGSTRNKSRVFVRAEVEDV------------------------KK-------------- 91  Pyrococcus furi...
WP_004082342  77 KEkerwekekykglkylegLIFGSQERKSSFSLEVKVEGE------------------------SQ---AL---Gky--- 123 Thermotoga
WP_009992994  67 IDrl-------------feDVFGSENKKSAVRLEVITDEG------------------------SD---NHfelS----- 101 Sulfolobus solf...
WP_010875967  68 EErlhc----------dacELFGCSGWSRKFIFRSREESD------------------------K--------------- 98  Methanothermoba...
WP_010980048  69 LNkl-------------leDFFGSTNFKSPIRVRIEIEDNfitifkaiwdfiirilenrkvtvkSE---NT---Q----- 124 Sulfolobus toko...

4L6U_A        91 -----MVWK-------------KKKGVTTR-VSQRAI-----------APGSKFTLLLTSDDEEVLKLACYs-------- 132 Archaeoglobus f...
WP_011012270  92 dknvgYIWF-------------SINLLGKRgTITHYY-----------PPGSRFRVVLESPSERVIKLATLs-------- 139 Pyrococcus furi...
WP_010896508 121 nnrrlHSSL-------------SKYKYVLFpFEDRKRdk-------hqDHTDYLNTDSPYTFTLHLEYIQFe-------- 172 Bacillus halodu...
WP_009990109 107 -----YEKL-------------NRVNVIIRgKEQENLip--------rDMNFTLEIFRSNDDPKYDEIVVGg-------- 152 Sulfolobus solf...
WP_011026630  83 -----KAYL-------------CMNDRRKKgEKGAAVn-----------YSERVRTSYAPNQEFILNFKFMp-------- 125 Caldanaerobacte...
WP_010880201  85 -----DAYL-------------AMNKRYGR-------------------YNNIKRKALEKNDTFRIDFIYSp-------- 119 Aquifex aeolicus
ZP_00075987  106 -----LVTL-------------DKDEVGNNwWLSTIFkknfnnnlsfgKFTFRIYPVGRGDKSEIIAQIKA--------- 158 Methanosarcina ...
WP_011011465  92 --------------------------------------------------GNIYRQASSWADKTIIVWSEYv-------- 113 Pyrococcus furi...
WP_004082342 124 ----mNNRF-------------SFTDDRLKdTKYALYgl--------yDKSGIYEYLQEGKNFIIILQTANdsikgiils 178 Thermotoga
WP_009992994 102 -----NVEL-------------DNVIDCLKaNREEKVnl--------dFRDNTLIIEIEGSTKIPISFKSNl-------- 147 Sulfolobus solf...
WP_010875967  99 ------------------------------------------------TLKVQITELRR-MEDVELALLNK--------- 120 Methanothermoba...
WP_010980048 125 -----NLNIadtiiiptininiGNSTIFKItENNHVIrvkr----ennPENNTLNITLDLNAKKLTATLNNn-------- 187 Sulfolobus toko...

4L6U_A       133 LIg----------------LVYFGGIG---FRC---SRGAGSLKISS 157 Archaeoglobus fulgidus DSM 4304
WP_011012270 140 LWa----------------LVSLGSVG---FRS---RRGTGSMKIVR 164 Pyrococcus furiosus
WP_010896508 173 VDninirde---vhaalwaWINFGGLG---ART---RRGCGSLYCKS 210 Bacillus halodurans
WP_009990109 153 VLi----------------tIAFLGIG---FSP---NRGFGRFIPAE 177 Sulfolobus solfataricus
WP_011026630 126 HFpkeheke---lknslmcLSLFGGIG---ARW---RRGFGSIIVKE 163 Caldanaerobacter subterraneus
WP_010880201 120 FFtykkel-----nttlqlLSFLGGIG---ARW---RRGFGSIQLKN 155 Aquifex aeolicus
ZP_00075987  159 LLs---------------iMSHVGAIG---AKS---QYGFGQFEMEN 184 Methanosarcina barkeri
WP_011011465 114 D------------------YFFFSVLD---KRR---NRKTKKIDIKT 136 Pyrococcus furiosus
WP_004082342 179 LLk---------------lVSTFSGFG---AKT---RKGFGEFEIVD 204 Thermotoga
WP_009992994 148 DIdkikdl------vyknkLLSFELLG---FKSikiDTKISDKEVIK 185 Sulfolobus solfataricus
WP_010875967 121 TLs---------------iIENYGAIGgklAHR---KYGIIKIKEND 149 Methanothermobacter thermautotrophicus
WP_010980048 188 QIelklrdktldkylrldkLSDFLSIPrimLDL---LKYNNKGVIVS 231 Sulfolobus tokodaii
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