3C4U


Conserved Protein Domain Family
fruc_bis_ald_

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TIGR01859: fruc_bis_ald_ 
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fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist
This model represents of one of several subtypes of the class II fructose-1,6-bisphosphate aldolase, an enzyme of glycolysis. The subtypes are split into several models to allow separation of a family of tagatose bisphosphate aldolases. This form is found in Gram-positive bacteria, a variety of Gram-negative, and in amitochondriate protists. The class II enzymes share homology with tagatose bisphosphate aldolase but not with class I aldolase. [Energy metabolism, Glycolysis/gluconeogenesis]
Statistics
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PSSM-Id: 130918
View PSSM: TIGR01859
Aligned: 11 rows
Threshold Bit Score: 424.467
Threshold Setting Gi: 5902756
Created: 8-Oct-2014
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3C4U_A         2 LVKGNEILLKAHKEGYGVGAFNFVNFEMLNAIFEAGNEENSPLFIQASEGAIKYMG-------IDMAVGMVKIMCERYPH 74  Helicobacter py...
P56109         2 LVKGNEILLKAHKEGYGVGAFNFVNFEMLNAIFEAGNEENSPLFIQTSEGAIKYMG-------IDMAVGMVKTMCERYPH 74  Helicobacter py...
P13243         3 LVSMTEMLNTAKEKGYAVGQFNLNNLEFTQAILQAAEEEKSPVILGVSEGAGRYMGg------FKTVVAMVKALMEEYKV 76  Bacillus subtil...
P42420         3 FVSMKELLEDAKREQYAIGQFNINGLQWTKAILQAAQKEQSPVIAAASDRLVDYLGg------FKTIAAMVGALIEDMAI 76  Bacillus subtil...
P47269         2 LVNFKLMLQKAKLGKYAIPHININNYEWAKAVLTAANQANSPIIVSVSEGALKYMSg------YSVVIPLVKGLIESLSV 75  Mycoplasma geni...
Q9PPP3         4 LVNAKKMIQNAYENHYAVAAININNLEWIKAALLAAQETNSPLLLATSEGAVKYMGg------YDNCYAMVVNLIKQMNI 77  Ureaplasma parv...
O65944         3 IVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAPVLIQTSMGAAKYMGg------YKVARNLIANLVESMGI 76  Streptococcus p...
WP_011024643   2 LVTGIEILEKAHKEGYAVGAFNTSNLEITQAIVEAAEETRSPVIIQVSEGGLKYAG-------IEAISAIVRTLAEKAt- 73  Caldanaerobacte...
O83668         9 LVNTKDLFAKAVKGGYAIPAYNFNNLEQLQAIIQACVETRSPVILQVSSGARKYANat---llRNMARGAVEYAHELGVD 85  Treponema palli...
WP_010865086   6 vkNTKEILEKASKERYAIGAFNFNNMEFLQAILEAAEEEKAPVIVATSEGAIKYIGkgdietgAKLAVEMVRTYAEKLS- 84  Thermotoga mari...
WP_010888228   2 LVTGKDILVPARAGKYAVGAFNTNNMEITQAIIHTAEKLRSPVIVQMSEGAIKYGG--------QDLANIVIDLATRAt- 72  Deinococcus rad...
3C4U_A        75 -IPVALHLDHGTTFESCEKAVKAGFTSVMIDASHHAFEENLELTSKVVKMAHNAG--VSVEAELGRLMGIEDNisVDEKD 151 Helicobacter py...
P56109        75 -IPVALHLDHGTTFESCEKAVKAGFTSVMIDASHHAFEENLELTSKVVKMAHNAG--VSVEAELGRLMGIEDNisVDEKD 151 Helicobacter py...
P13243        77 tVPVAIHLDHGSSFESCAKAIHAGFTSVMIDASHHPFEENVATTAKVVELAHFHG--VSVEAELGTVGGQEDD--VIAEG 152 Bacillus subtil...
P42420        77 tVPVVLHLDHGSSAERCRQAIDAGFSSVMIDGSHQPIDENIAMTKEVTDYAAKHG--VSVEAEVGTVGGMEDG--LVG-G 151 Bacillus subtil...
P47269        76 kVPVTLHLDHG-SYDACIQALQAGFSSVMFDGSHLPFEENFNKSKKLIEIAQKTN--ASVELEVGTIGGEEDG--VIG-Q 149 Mycoplasma geni...
Q9PPP3        78 kTPVCLHLDHG-TYEGCIKAINAGYSSIMYDGSKLSIEENIKNTKELLTITKLKG--VSVEVEVGSIGGTEDG--ITS-E 151 Ureaplasma parv...
O65944        77 tVPVAIHLDHG-HYEDALECIEVGYTSIMFDGSHLPVEENLKLAKEVVEKAHAKG--ISVEAEVGTIGGEEDG--IIG-K 150 Streptococcus p...
WP_011024643  74 -VPIALHLDHGTDFNTIMKCLRNGWTSVMIDASKFPLEENIQRTRKIVEIAHSMG--VSVEAEIGKIGGTEDHitVDERE 150 Caldanaerobacte...
O83668        86 -IPIVLHLDHGDSLELCIDCIESGFSSVMIDGSALPYDENVALSRKVCEYAHARAdyVTVEGELGVLAGVEDD--VVAEK 162 Treponema palli...
WP_010865086  85 -VPVALHLDHGRDFKVIMAAIKAGYSSVMIDASHLPFEENLRETKRIVEIAHAVG--ISVEAELGKLKGIEDN--VVEKE 159 Thermotoga mari...
WP_010888228  73 -VPVALHLDHGSSYESALNAIKMGFTSVMIDASHHPFEENVHETKRVVEAAHAMG--ISVEAELGRLGGIEEHvvVDEKD 149 Deinococcus rad...
3C4U_A       152 AVLVNPKEAEQFVKESQVDYLAPAIGTSHGafKF--KGE------------PKLDFERLQEVKRLTN-IPLVLHGASaip 216 Helicobacter py...
P56109       152 AVLVNPKEAEQFVKESQVDYLAPAIGTSHGafKF--KGE------------PKLDFERLQEVKRLTN-IPLVLHGASaip 216 Helicobacter py...
P13243       153 VIYADPKECQELVERTGIDCLAPALGSVHG--PY--KGE------------PNLGFKEMEEIGKSTG-LPLVLHGGT--- 212 Bacillus subtil...
P42420       152 VRYADITECERIVKETNIDALAAALGSVHG--KY--QGE------------PNLGFKEMEAISRMTD-IPLVLHGAS--- 211 Bacillus subtil...
P47269       150 GELANVDECKQIAS-LKPDALAAGIGNIHG--IY--PKNw-----------KGLNFPLIETISKITN-LPLVLHGGS--- 209 Mycoplasma geni...
Q9PPP3       152 GELANIDDCYQMCL-LDIDMLACGIGNIHG--IY--PKNw-----------KGLNFNLLKEINNKVN-KPIVLHGGS--- 211 Ureaplasma parv...
O65944       151 GELAPIEDAKAMVE-TGIDFLAAGIGNIHG--PY--PVNw-----------EGLDLDHLQKLTEALPgFPIVLHGGS--- 211 Streptococcus p...
WP_011024643 151 ASMTDPEEALRFAKETGVDYLAIAIGTAHG--PY--KGE------------PKLDFERLKRIKELLN-MPLVLHGAS--- 210 Caldanaerobacte...
O83668       163 SHYTMPDEVEDFVKKTGVDSLAISIGTSHGraKF--TPEqctrnadgvlipPPLRFDILAEIEKRIPgFPIVLHGASsvp 240 Treponema palli...
WP_010865086 160 SVLVDPEEAKVFVKETEVDFLAPAIGTSHGafKF--KGE------------AQLDFERLKKVKEYTQ-IPLVLHGASmvp 224 Thermotoga mari...
WP_010888228 150 AFLTDPDEAVKFVEETGTDYLAIAIGTSHG--AYkgKGR------------PFIDQARIKKIGELLS-IPLVAHGSS--- 211 Deinococcus rad...
3C4U_A       217 dnvrksyldaggdlkgskGVP---------------------FEFLQESVKGGINKVNTDTDLRIAFIAEVRKVAN---- 271 Helicobacter py...
P56109       217 dnvrksyldaggdlkgskGVP---------------------FEFLQESVKGGINKVNTDTDLRIAFIAEVRKVAN---- 271 Helicobacter py...
P13243       213 ------------------GIP---------------------TADIKKSISLGTAKINVNTENQISSAKAVRETLA---- 249 Bacillus subtil...
P42420       212 ------------------GIP---------------------QDQIKKAITLGHAKININTECMVAWTDETRRMFQ---- 248 Bacillus subtil...
P47269       210 ------------------GIL---------------------ENDVKKAISLGICKLNINTECQLAFAHEIRKYIEsnkd 250 Mycoplasma geni...
Q9PPP3       212 ------------------GIS---------------------DEQILKAINLGVAKININTECQIAFSNALQDHLTkagd 252 Ureaplasma parv...
O65944       212 ------------------GIP---------------------DEQIQAAIKLGVAKVNVNTECQIAFANATRKFARdyea 252 Streptococcus p...
WP_011024643 211 ------------------GVP---------------------EEAIKKAVSLGINKINIDTDVRQAFTARLRRLLE---- 247 Caldanaerobacte...
O83668       241 veyvreveryggnlpdsvGIP---------------------EEQLRKAAKSAVCKVNIDSDGRLAMTAAIRRVLT---- 295 Treponema palli...
WP_010865086 225 qdivklaneygaelsgakGVP---------------------EDMLKKAIELGINKINTDTDLRITFVAYLRKVLS---- 279 Thermotoga mari...
WP_010888228 212 ------------------GVPaeivqrlraaggeigdaagiaDEDLTEAAQYGIAKVNVDTDLRLASTVGIREVLK---- 269 Deinococcus rad...
3C4U_A       272 -----EDKSQFDLRKFFSPAQLALKNVVKERMK-LLGSANKI 307 Helicobacter pylori
P56109       272 -----EDKSQFDLRKFFSPAQLALKNVVKERMK-LLGSANKI 307 Helicobacter pylori 26695
P13243       250 -----AKPDEYDPRKYLGPAREAIKETVIGKMR-EFGSSNQA 285 Bacillus subtilis subsp. subtilis str. 168
P42420       249 -----ENSDLYEPRGYLTPGIEAVEETVRSKMR-EFGSAGKA 284 Bacillus subtilis subsp. subtilis str. 168
P47269       251 --ldlNKKG-YDPRKLLKEPTQAIVDTCLEKID-LCGSRNKA 288 Mycoplasma genitalium G37
Q9PPP3       253 --lilSKQ--YDPRKILAYGVDAIKNTIIDKFT-KFNSLNKI 289 Ureaplasma parvum serovar 3 str. ATCC 700970
O65944       253 neaeyDKKKLFDPRKFLADGVKAIQASVEERID-VFGSEGKA 293 Streptococcus pneumoniae
WP_011024643 248 -----EDKEVYDPRKILGPCKEAMKEVIKQKMI-LFGSSLKA 283 Caldanaerobacter subterraneus
O83668       296 -----TKVDEFDPRKYLGPARDELKKLYMHKNKeVLGSAGRA 332 Treponema pallidum subsp. pallidum str. Nichols
WP_010865086 280 -----EDKSQIDPRKIFKPVFEQVKEIVKERIR-IFGSSGKA 315 Thermotoga maritima
WP_010888228 270 -----ATPKEFDPRKIFGPARDVMSQIVEHKMG-VLGSVGKA 305 Deinococcus radiodurans
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