Conserved Protein Domain Family
Trypano_RHS
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TIGR01631: Trypano_RHS 
trypanosome RHS (retrotransposon hot spot) family
This model describes full-length and part-length members of the RHS (retrotransposon hot spot) family in Trypanosoma brucei and Trypanosoma cruzi. Members of this family are frequently interrupted by non-LTR retrotransposons inserted at exactly the same relative position.
Links
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Statistics
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PSSM-Id: 273724
Aligned: 5 rows
Threshold Bit Score: 1120.68
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
AAL14352   46 AAQPPQIRQRTEG--GPNWTMDSKVRDVLLDDYAGLRNLTLHDFLLKKFLNTYN---TENVAMDVFVQSPGDYILDAGIL 120 Trypanosoma brucei
AAL14353   45 ARRFLKRLRGDEE--GPTWTMNSSIEDVLLQRFAGLRDMKLHDLLNHHFGETLG---TSNVSVGVFVQSPEDYIVNAKFL 119 Trypanosoma brucei
AAL14357   27 DAEPPAVQQRVENnnQPQWRLFSRVDAVLLDGLPHPRNMMLNDFLRRNFGRRYNvneENNVSMFVFVLEPEEYINDVNAL 106 Trypanosoma brucei
XP_951497  39 aaqppqIRQRTEG--GPNWTMDSKVRDVLLEDYAGLRDMTVNDFIQKFVGGTFAvaeAENVRMPIFVQSPEDYILDARLL 116 Trypanosoma brucei...
XP_804137  37 TDQLAATRRRMEEarQPQWTLDSRVEDVLLEATARSTNMKLGDFLWQNFGGRGVvdtNRNVLLKEFLKEPARYIRDAGAL 116 Trypanosoma cruzi ...

AAL14352  121 ERIQRLYQFEeykelydqFsemKRKARYLDEKEIYYLSQWEEKGTVEIREFVGPVARGR------LDGAVTAAKRAEKRA 194 Trypanosoma brucei
AAL14353  120 GRIQRLDEFQ--------L---LRAVIYLPRNRIEDIHQWEENATAQIREFVGPVAATK------LDSALRIAKEARKRA 182 Trypanosoma brucei
AAL14357  107 NRIFATTEYKvy----krFvsvYGFFEDEGILNLQRWQQADEVVKARLQVNIRGLRDGErlwivvTNMLNDALNEALQGA 182 Trypanosoma brucei
XP_951497 117 GRVRGTDEFKtv----ktAidlSEKVDYLDEKEISTLSQWEEKGKGEIREFVGPVARGR------LDAAVIAAKRAEKRA 186 Trypanosoma brucei...
XP_804137 117 NEIHASSHYErvrndlgnKvvfDEDVRKLEENGVNTLIDWLEAAAG-VKAVVHCITRVS------LDPFLEDVRNSMR-- 187 Trypanosoma cruzi ...

AAL14352  195 AQTAD-G-SELKGVYDSIYNATWSYVESGHDTEPLGMKVFNGR--PPHMWTKEEVDVSHTPETMNEPLP-RHGNLEIAVL 269 Trypanosoma brucei
AAL14353  183 HQTAD-G-VELKGVYESIYNATWGYVESGHNDLPLGMKVVGNSdgEPELWTEEEVNVSHTPYDLCDPLP-RHGNLEIAVL 259 Trypanosoma brucei
AAL14357  183 ILAAGgA-VNLEGVYDSIYNAKWSHIIIDNGTQPLGMRLVDGMpnEGLMWKEEEVDVVPEIEEALEQKPeRTKGVELLVL 261 Trypanosoma brucei
XP_951497 187 AQASD-GaVYLEGVYDSIYNAKWSYVMSGYDEEPLGMKVFDGR--PPHMWTEEEVDINPLPANLDARVPeRPYGLEIFVL 263 Trypanosoma brucei...
XP_804137 188 MSASN----ILEGFYESVYNARWSHLVEVPGGEGTGMEVKEGK--PPQPWTYKKVGYTLERDDGAQQSG--AARLRLMVL 259 Trypanosoma cruzi ...

AAL14352  270 TSQMGWPYTSFEKNPNDYDINHEKgveyvfksDVYIRREALRVWYKVENVLNRWLMDEvI----VDDASNVLIGTPGIGK 345 Trypanosoma brucei
AAL14353  260 TSQEGWPYNSFSTPEHAIQEEAEEpgdyvfdgDVYIRREVMRVWYLVKHRLDLWLGPGvN----KKQIPCVLVGTPGIGK 335 Trypanosoma brucei
AAL14357  262 TSEMGWPYTGFARGSNs---------------DIFIRREELRVWNVVRNGIELWRTQRaLpgclHFPRAYLAIGNPGIGK 326 Trypanosoma brucei
XP_951497 264 TSEKGWPYNRFALDDAEICWENFK--------HVYIRREIMRVWYIIQRGLQGRWVEKa-----DITPRHIVIGTPGIGK 330 Trypanosoma brucei...
XP_804137 260 TSDKAWPCTWNRKGVEST-----R--------DCHVNCEVERVWQIVKGDLTEWSSSHgKa--dFEPERRVLIGTPGIGK 324 Trypanosoma cruzi ...

AAL14352  346 SFSVGSLLLYKLLHYEASQLQIIIYVVRGKAYVFHKPIGGRAGYVTFYNDYGNAFTVVEQIIGgsrsgEDIKGYVIFDVD 425 Trypanosoma brucei
AAL14353  336 SFGVGSFLLQRLLHYDSELLRNIAYFVKGRAYIFFRATNDHPGKVVFYEKEKDGLDAVEAFVV-----EKVLGYIIYDFW 410 Trypanosoma brucei
AAL14357  327 SQNLGSFILYNLLHYDAEELPVVAYFRGVAAYIFEKSGGGGVCRVKKYSKG-AAMDLLEVISS-----N-TRGYVIYDFV 399 Trypanosoma brucei
XP_951497 331 SYGVGSFLLHSLLHFHEGMFDVVAYFTDGIAYLIYNKKPGEEGRVEEYEDVKAAVRVIAALVF-----KKKKGHIIVDIC 405 Trypanosoma brucei...
XP_804137 325 SMAAGSYLLYQLLHCDVEKLQMVAYFIADRTFLFDKTSR----TVSTYMSDSSNASFVRSLSD-----RGVKGYIIYNVA 395 Trypanosoma cruzi ...

AAL14352  426 KD--HPAPTKPPAGCAGIALSSPNVKQFHEWSKQN-TASDIYMNCDTLKDLEAIHISRWGKIAPAY-----KWSpPVAKE 497 Trypanosoma brucei
AAL14353  411 KDrhQPIPADLPGAWPVIVLTSPDPNNYKDWKEPR-GCEFLCINCYEEVELKAAVAWRRLSKLEES-----KIT-EAHII 483 Trypanosoma brucei
AAL14357  400 KKg-EQPPADVAPKWGSILISSPNLRNFDSWFQQReRCARIVVNCWEMTEMRAFFSRIGPMLYPE-----------ATPV 467 Trypanosoma brucei
XP_951497 406 KNaqTPPDGLPVHAWGVTLLTSPDEAHFHHWSKDK-RDVGIIINCDDVRDMKAFVAWTKLSVASGYaaldeEAQ-ARIVE 483 Trypanosoma brucei...
XP_804137 396 EPddEPFGYSSPSGWGVVLVSPPFESNYKEWVKRR-GATRIVMDCPGESDVKAMCVWMGRHQPVR--------------- 459 Trypanosoma cruzi ...

AAL14352  498 KIESEWQEIQARIRIVGPLLRHIG-RLSSYNRQEGKVQEAIGKMKDDDMNDYAKYFQNAAMWQTDEVSHKLVGVVRVKEE 576 Trypanosoma brucei
AAL14353  484 NLENEWQKTLGWIKKVGPLARQVLeGEKRYKGRVREINEALAEISRGDDSHYMKVLNSRVQWRQDGTTYMLAKLVRVVTE 563 Trypanosoma brucei
AAL14357  468 GLREKWEMYESRVEFVGPSLRYVFdGAKHATREDDIDNEINSIKSHERRELYIGVVGNKGGWRESDASHKLVKIVRACGR 547 Trypanosoma brucei
XP_951497 484 ELENEWETIKSRINVVGPVPRCVY-NSAGYTKRVSQAKKMITSINGDNKSHYEDIMGKIADWRNDKVTHRLVKIVRVRDA 562 Trypanosoma brucei...
XP_804137 460 EQAEDWKVVKSHMDEVGPIPRYIF-DERKYDNWVQRCHKTVDEATSSVIAQCNGF--GRGSWDCKKVLYWIAKAVRVRGG 536 Trypanosoma cruzi ...

AAL14352  577 klLCEMYRCRPLSSYTGQAILDFLIPWLTDKYAAMSALLSNRAIAAYMFEKSGIEALSHENTLTELARELQGLS----FA 652 Trypanosoma brucei
AAL14353  564 --NGEECRNRAVSIDIEQKLRVWANTACMRDNYLRKVFRGKEERAADEFENVGVYAFTMGNVVQTIVTHLRYLP----RV 637 Trypanosoma brucei
AAL14357  548 n-NGEIYICVPHSESIKKRIIQKICEITAQNLARLAGLIPTREMIPALFEYNAIKALGFPKVLSMITQMTKPLPergvRE 626 Trypanosoma brucei
XP_951497 563 geSVDEYRCRPLSVCIGNAIFFKLLAIDVEKMAICQVTMSDESAAANVFESRALLSLLFPRVFKVIAENLKYLQ----RP 638 Trypanosoma brucei...
XP_804137 537 dcSCEFFSNVPVSAHLGNKTLFKSAKLMQQRDFNSLISELTDYLISENFGRCTVFAFLNGSFVRGIERRPREL-----RP 611 Trypanosoma cruzi ...

AAL14352  653 RNQIPQS-VLQVLQEPRLIGPSIVVPEDVPIVAGAEIQYMKLYKPQSRSFPVVDAFFFVESP--------------KTFV 717 Trypanosoma brucei
AAL14353  638 GEEMDSN-VSVLASGNAVGRVPTSLRQFNPETTGQDIEVGCFYRPVQGNFPVVDAFFFVTEPavdreg---raiitTTIV 713 Trypanosoma brucei
AAL14357  627 QEIAQNIsVLRHVEEKYLNFGNAADFTDGYGMVIRSPSLFQAYKALP-NFPVLDAFFVVDPDaiaedkk-qqrrekKTIV 704 Trypanosoma brucei
XP_951497 639 GGLEEKRcILNDMAPQQLRLIGQKALPATHQQPIDNCEYMVLYRPATGNEPVVDGFFFVEGRfrrnrdgaappttpNIAV 718 Trypanosoma brucei...
XP_804137 612 STQRQSHrCALAVYSQEGSTRHHVLPPLEHFSERIDVECGVLYVTEVENFPLVDAFFFMESKp-------------MTLV 678 Trypanosoma cruzi ...

AAL14352  718 GLQYTVSGRHPCSTGGLFKMKRYLRSYFQG-----WDNFSNDMVWEIIYVQRVDSEKITKPQCCERTDrd--eGQNNeve 790 Trypanosoma brucei
AAL14353  714 LLQATVAPTHHTTREKVDKFIKAMKQLFGE-----WDKLARNLKWELIYIQYSDSKPIEERQKCEPVG-----GRGDhtt 783 Trypanosoma brucei
AAL14357  705 MLQYTTAESHDTKTGTVLGMLKKLLNPTTNpsdeyWKEVMGQYQWEMIYVQHPDATPMRVKQRCDFTDgk-adDENHrhv 783 Trypanosoma brucei
XP_951497 719 LLQVTKSERHPTTTDKVKKFRENMARYFSD-----WGAFSRNMVWEMIYINSVNGGVITRWQLCDGDNpa--eAAD---- 787 Trypanosoma brucei...
XP_804137 679 GLRMAAAGGHHTTTSTVRQFTEYLAAYFNG-----WEELSRQLSWEIIYVQHADSTPMNDWQRCDVVDsnnvsGADNnei 753 Trypanosoma cruzi ...

AAL14352  791 erFWKreVRQFAVSL 805 Trypanosoma brucei
AAL14353  784 elWNK--INQFQVKM 796 Trypanosoma brucei
AAL14357  784 emFWKndVKQYLVKF 798 Trypanosoma brucei
XP_951497 788 --MWRn-MAQYQVTL 799 Trypanosoma brucei TREU927
XP_804137 754 avFWNekVRQYQVSI 768 Trypanosoma cruzi strain CL Brener
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