This model represents one of a large number of mutally dissimilar families of phage holins. Holins act against the host cell membrane to allow lytic enzymes of the phage to reach the bacterial cell wall. This family includes the product of the S gene of phage lambda. [Mobile and extrachromosomal element functions, Prophage functions]
Jiyao W et al.(2023). "The conserved domain database in 2023.",