4IDH


Conserved Protein Domain Family
phage_term_2
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TIGR01547: phage_term_2 
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phage terminase, large subunit, PBSX family
This model detects members of a highly divergent family of the large subunit of phage terminase. All members are encoded by phage genomes or within prophage regions of bacterial genomes. This is a distinct family from pfam03354. [Mobile and extrachromosomal element functions, Prophage functions]
Links
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Statistics
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PSSM-Id: 273684
Aligned: 12 rows
Threshold Bit Score: 316.273
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
4IDH_A        35 HRYKVAKGGRGSGKSWAIARLLVEAARR------QPVRILCARELQNSISDSVIRLLEDTIEREGYS--AEFEIQRS--M 104 Shigella phage Sf6
AAK28891      15 HRYKVAKGGRGSGKSWAIARLLVEAARR------QPVRILCARELQNSISDSVIRLLEDTIEREGYS--AEFEIQRS--M 84  Salmonella phag...
P45916        18 QKFQFLVGGYGSSKSYHVALKIVLKLLR------EKRTALVIREVYDTHRDSTFSLFDELVSDLKLD--HIVRCVSSpmQ 89  Bacillus subtil...
AAF30576      29 FNEINLLGGRSSGKTFATLDFLSSLVAI------KQQNAIYVFRQNISDAKKIFSDYLNFLDQKQL---LKFAKINHseR 99  Ureaplasma parv...
AAK27894      53 QEAIICDGSVRAGKTVVMALSYILWSMTnf----sGQQFGMAGKTIGSFRRNVLRPLRSMLESEGYNv-YDSRSENMitI 127 Lactobacillus j...
BAA97626      25 PKVLIASGAKRAGKTYVFILLFLMHIATyk---dKGLNFIIGGATQASIRRNILDDMELILG-------RELTLDKSn-A 93  Staphylococcus ...
CAC97621      24 VTLEVNEGTPRSGKTTADIFKMAYIYSIse----dQNHLVTAYNQEQAFRLFMDGDGFGLMHIFG-Nl-AEMKHDEHgdH 97  Listeria innocu...
AAB00186      32 ADEYNEIGSRYSAKTFMIKDNVVAKCCAisllvgKPIFIIAVMKMNKDIRNGVFKNIQNTLNDMNIN--YKVNLSEN--S 107 Spiroplasma citri
WP_031645655  33 HNHIIAKGGRSSMKSSVISLKLVEKKMAn-----PQSNMVCLRKVANTLYKSVYQQIKWALYEMGVA--DQFKFGKSpmE 105 Listeria monocy...
WP_000169948  28 nftevhygggssgkshgVIQKVVLKALQdw---kYPRRILWLRKVQSTIKDSLFEDVKDCLINFGIWdmCLWNKTDNk-- 102 Staphylococcus ...
WP_010890296  19 AEIFIYYSSRGTGKTYDIATVNLERKFSa-----DGGDTLAIRKKKNKTTQSIHKEILELLSIYNLR--KFFNISKAkiE 91  Lyme disease sp...
WP_010258365  61 YSKVIFSGGIASGKTFLASYLLVKKLIEnksfyeQDTNNFIIGNSIGLLMTNTVKQIEKICSLLGID--YEKKKSGQs-F 137 Lyme disease sp...

4IDH_A       105 IRHLGt--NAE--FMFYGIK--NNPTKIKSLEG-------------IDICWVEEAEAVTKE-SWDILIPT-IRk---pFS 160 Shigella phage Sf6
AAK28891      85 IRHLGt--NAE--FMFYGIK--NNPTKIKSLEG-------------IDICWVEEAEAVTKE-SWDILIPT-IRk---pFS 140 Salmonella phag...
P45916        90 IRFSN---GSR--IIFKGM---DKPAKLKSINN-------------ISLIWIEECSEVKYE-GFKELLGR-LRh---pTL 143 Bacillus subtil...
AAF30576     100 TVIIN---GWT--VMFEALN--ETRNNINKGAKvgfrl---wtqarYVFAFFEEASQLDFN-LVKNSQQS-LRg---tKD 164 Ureaplasma parv...
AAK27894     128 SKNGHt--NFY--FIFGGKD--EASQDLVQGIT-------------LAGFFFDEVALMPQS-FVNQATAR-CSv---tGS 183 Lactobacillus j...
BAA97626      94 VKIFG---NKV--YVFDGQNs-DAWKKARGFTS--------------AGAFLNEGTALHNM-FIKEVFSR-CSy----KG 147 Staphylococcus ...
CAC97621      98 LLIHSpngPKK--IYYKGG---GKINSVGAITGmslgtvtfleinlLHKDFIEECFRRTFA-A----------------- 154 Listeria innocu...
AAB00186     108 FTLDN---GTY--IICKGLHsqTKREKLKAFADlnk--------yeFAIEWREEADQLTKD-DMSELDYA-VR-----GA 167 Spiroplasma citri
WP_031645655 106 IIHKEw--GTG--FYFSGC---DDPAKLKSMKIpv---------gyVSDLWFEELAEFSGVtDIDVVEDTfIRedlpdGQ 169 Listeria monocy...
WP_000169948 103 VELPN---GAV--FLFKGL---DNPEKIKSIKG-------------ISDIVMEEASEFTLN-DYTQLTLR-LRe---rKH 156 Staphylococcus ...
WP_010890296  92 SKSLIf--GKKraFVFEGGH--DTR-DLKSYAH-------------FKDLWLEEANQFSAD-DIEMLVPT-MRe---qGG 148 Lyme disease sp...
WP_010258365 138 CKIAGl--KL---NIYGGKNr-DAFSKIRGGNS--------------AIIYVNEATVIHRE-TLLEVIKR-LR-----KG 190 Lyme disease sp...

4IDH_A       161 E---IWVSFNPKNILDDTYQRFVVN----PPDDIC----------------LLTVNYTDNPHFP----EVLRLEMEECKR 213 Shigella phage Sf6
AAK28891     141 E---IWVSFNPKNILDDTYQRFVVN----PPDDIC----------------LLTVNYTDNPHFP----EVLRLEMEECKR 193 Salmonella phag...
P45916       144 Pl-hMILSTNPVGEDNWTFKHFFKDdr-eKRFVLDdkelyekriivsndtyYHHSTADDNLFLP----ESYVQQLEELKE 217 Bacillus subtil...
AAF30576     165 TqvvSIFASNPWTSEHWYIENFNNHla-eNEFSIQqkpyyey--svvdkklFLRSTYRANKFTS----QQEIEQFEWWKD 237 Ureaplasma parv...
AAK27894     184 K---MWFNCNPSGPFHWFKLNWIDQm---KDKRAL----------------RIHFTMHDNPSLD----SVTINRYERMYS 237 Lactobacillus j...
BAA97626     148 Ar--ILIDTNPENPMHPVKKDYIDKsg-qRLSNGRln------------ikAFQFTLFDNTFLD----EEYIESIIASTP 208 Staphylococcus ...
CAC97621     155 KnrfHLAELNPPAPNHPVLEIFSQYe---KSGRYK----------------WRHWTAKDNPALS----DERKQEIYNEVK 211 Listeria innocu...
AAB00186     168 KrkfIINSSNPESLKRYIIKYCNEImp-fDEEILSseypd------qigkfKINYYEKNEKFTKtviiHYSSWRLNSYLD 240 Spiroplasma citri
WP_031645655 170 Ev-tIYMSFNPPRNPYEWVNEYVDSkrsdDDYLIH----------------HTTYLDDEKGFLS----KQIIKKIEKYKK 228 Listeria monocy...
WP_000169948 157 VnkqIFLMFNPVSKLNWVYKYFFEHg--ePMENVM----------------IRQSSYRDNKFLD----EMTRQNLELLAN 214 Staphylococcus ...
WP_010890296 149 r---IYMSSNPVPKSHWLYKRYLSNq---DNPAVC----------------IIKSTYRDNPFLNggdvQAWLEKQRLAYH 206 Lyme disease sp...
WP_010258365 191 Ke-iIIFDTNPESPAHYFKTDYIENt---DVF--K----------------TYNFTTYDNPLNS----ADFIQTQEKLYR 244 Lyme disease sp...

4IDH_A       214 RNPTLYRHIWLG-EPVSasdmaiikrewleA-------------A-----TDAHKKLGWKAKGAVVSAHDPSDt--GPDA 272 Shigella phage Sf6
AAK28891     194 RNPTLYRHIWLG-EPVS-------------AsdmaiikrewleaA-----TDAHKKLGWKAKGAVVSAHDPSDt--GPDA 252 Salmonella phag...
P45916       218 YDPDLYRIARKG-HFGVngi---------------------rvlP-----QFEERPHEEVMTAISNINRPLKRv--GMDF 268 Bacillus subtil...
AAF30576     238 IDYSKYRVISLG-LSGSv-------------------------eG-----AIYARSLSVMHEPYGEYDNYAMQffgGMDW 286 Ureaplasma parv...
AAK27894     238 G--VFYQRYIQG-LWVMs--------------------------E-----GVIYDNFDKDTMVVNELPNHFEKyyvSCDY 283 Lactobacillus j...
BAA97626     209 TG-MFTDRDIYG-KWVSa--------------------------E-----GVVYKDFKEKVHYIKEEEFKTKQi--KRKY 253 Staphylococcus ...
CAC97621     212 HSAYLLQRDWYG-KRVLp--------------------------A-----GIIYETFDVEANQIKKMQGHPIEmvfFGDG 259 Listeria innocu...
AAB00186     241 VDVKRKQLILEK-LDTE-------------RarvwswglpgntsG-----SIFARYLDIMQATDIIQPTKLLGgvdIANA 301 Spiroplasma citri
WP_031645655 229 NDLDYYRWMYLG-EVIG-------------L-------------GdnvynMNLFQPLKAIPADDRLI---LIDf--AIDT 276 Listeria monocy...
WP_000169948 215 RNPAYYKIYALG-EFAT-------------L-------------D-----KMVFPKYEKRLINKDELRHLPSYf--GLDF 260 Staphylococcus ...
WP_010890296 207 GNDIGFRIEVLGeEFDF-------------G-------------T-----ARLIKKFNVCGPEILSRANGSYYt--GIHV 253 Lyme disease sp...
WP_010258365 245 RFPAYRARVLYG-EWIL-------------N-------------E-----STLFNEMIFNQDYEFKSPIMYIDp--AFSV 290 Lyme disease sp...

4IDH_A       273 KGY--ASRHGSVVKRIAEGLLMd-iN-EGADWATSLAI-----EDGADHYLWDGDGVGAGl-RRQTTEAFSGKKITATMF 342 Shigella phage Sf6
AAK28891     253 KGY--ASRHGSVVKRIAEGLLMd-iN-EGADWATSLAI-----EDGADHYLWDGDGVGAGl-RRQTTEAFSGKKITATMF 322 Salmonella phag...
P45916       269 GFV--ESYNAVVRVAVDHEKKY---L-YIYWEYYKNG--------LTDDKT--AEELKEFaeTKELIKADSAEPKTIRYF 332 Bacillus subtil...
AAF30576     287 GDGtsSSSSDTACLFGSISKENg--IeILDEMVYNNNVnpltsEQQIELVVRWFIKKQQEvnVKIVIYIDNAHLRYFYET 364 Ureaplasma parv...
AAK27894     284 GTL--N-PTAFLLWGRNHGVWY-----LVKEYYYSGRT-----TSRQKTDEEYCHDLKEFlgDIRAEMIIDPSAASFSTT 350 Lactobacillus j...
BAA97626     254 AG---------VDWGYEHYGSI---M-VVAEDFDGNKY-----VIEEHAHRH--KEIDDWvaIAKGVIKRHGDILFYCDT 313 Staphylococcus ...
CAC97621     260 GQQdaTVCECYVITEHEAEGGYtynLnQVATYYHSGRD-----TGQVKAGSTYAIEIKQFiqWCMKEYEVPVNEPVFIDP 334 Listeria innocu...
AAB00186     302 TSPkgHTTAASFWLYNSFDKKAykvAeYTHSNATQQFKte--lEQVKDILEFYNNQLNKYfnLIQQGISINVDDSAFSTL 379 Spiroplasma citri
WP_031645655 277 GHQ--VSATTYLSFGLTAKRNV---I-LLNTYYYSPAN-----QVVKKAPSEYSKELRDFmtKVVGNYNTNVDMQTVDSA 345 Listeria monocy...
WP_000169948 261 GYV--NDPSAFIHSKIDVKKKK---L-YIIEEYVKQG-------MLNDEI---ANVIKQLgyAKEEITADSAEQKSIAEL 324 Staphylococcus ...
WP_010890296 254 KGN--R----ICFLEILVGRIS-----YLPVVIITNAC-----SKVLLSKTDYQSEINKFkgVFVLPTAREELKYVFSRF 317 Lyme disease sp...
WP_010258365 291 GGD--NTAICVLERTFEKFYAY---I-YQDQKPVSDSL-----MLASIQVLIENFNVNTVyiEERDSTKGDGILTKTILF 359 Lyme disease sp...

4IDH_A       343 K-GsespfDEDAP-----YQAGAWADEVVQGDNVRTIGDVFRNKRAQFYYALADRLYLtYRAVVHGEYADPDDMlsfdke 416 Shigella phage Sf6
AAK28891     323 K-GsespfDEDAP-----YQAGAWADEVVQGDNVRTIGDVFRNKRAQFYYALADRLYLtYRAVVHGEYADPDDMlsfdke 396 Salmonella phag...
P45916       333 Q-Q-------HGFn------MVGARKYQGSRLQYTKKIKRFRKIICSDRCENTIYELKpLAYATDKLGNIIEDE------ 392 Bacillus subtil...
AAF30576     365 F-NatfkrIAFQYn----MYGSELVFAPAIKHAIWDRVVLVNYMLASGKLRFSKNACPkLYKDLKNCYVVLPKTi----- 434 Ureaplasma parv...
AAK27894     351 L-R---------Q---------NGFKVRKAKNDVLDGIRVTQTAMNEGKIKFSMNCPNlFKELASYVWDDKAA------- 404 Lactobacillus j...
BAA97626     314 A-R-----PEHIE-----RFRREKIKARYADKAVIAGIEVISRLFKLNKIFIIKEKVSlFKEEIYN-YVW---------- 371 Staphylococcus ...
CAC97621     335 A-CrwlreELEKVgvdtaGADNNAHDVTGKAQGIEVGIERMQSLLSERRYLLVEQPNDqYDHYSWLQEIGMYVR------ 407 Listeria innocu...
AAB00186     380 Q-SlsrekYNYNF-----GQYMTFKQAQKQKFKVRHRVEAFTMLINTNQLKWLWEKCP-VSKNQYELIQWEDKP------ 446 Spiroplasma citri
WP_031645655 346 EgG-----LRNQY-----YKDYGVSLHPVAKGKKVDMIDFVCDLLAQGRFYYLDIPENqIFIEEHRKYQWDVKTv----- 410 Listeria monocy...
WP_000169948 325 R-N-----L--GL-----KRILPTKKGKGSVVQGLQFLMQFEIIVDERCFKTIEEFDNyTWQKDKDTGEYTNEP------ 385 Staphylococcus ...
WP_010890296 318 G-R-------------------------GTLLAKKRNLYSLSDYLIPSNLNVVNKPETtDVISEFNETEYYY-------- 363 Lyme disease sp...
WP_010258365 360 L-R-----NKSSH-----YFKVAPIKPL---SNKFKRICALIPLFESRKIEFLKIISKnVISDIYS-YKGD--------- 415 Lyme disease sp...

4IDH_A       417 aigekmlEKLFAELTQIQRK-FNNNGKLELMTKVEM 451 Shigella phage Sf6
AAK28891     397 aigenilEKLFAELTQIQRK-FNNNGKLELMTKVEM 431 Salmonella phage HK620
P45916       393 -------FTIDPHTLSAIWYaLDDYEVTDLKEESKG 421 Bacillus subtilis subsp. subtilis str. 168
AAF30576     435 ------kEDTKKERSHEHTHtINALEYLMCAFHLYF 464 Ureaplasma parvum serovar 3 str. ATCC 700970
AAK27894     405 -------EHGEDKPVKQHDHaCDAMRYFVYTIIYKK 433 Lactobacillus johnsonii prophage Lj965
BAA97626     372 -------KDNADEPVKLNDDtLDALRYAVYTANKPS 400 Staphylococcus phage phiETA
CAC97621     408 -------DENSGKPVDKNNHaMDTSRYATNYFYRNY 436 Listeria innocua Clip11262
AAB00186     447 -------EAREDKVLDLYDDtFDSDFYALHFELIPM 475 Spiroplasma citri
WP_031645655 411 -------NTDKPEVIKEDDHtCDAFQYYVKDNLRKL 439 Listeria monocytogenes
WP_000169948 386 -------VDTYNHCIDSLRYsVERFYRPVRKRTNVS 414 Staphylococcus aureus
WP_010890296 364 -------DESSAEDSEVTNFvMQKDLVYIPAFLNAI 392 Lyme disease spirochete
WP_010258365 416 -------GKTKDDALDSLANaYLLLTLNYKEKLFHF 444 Lyme disease spirochete
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