Conserved Protein Domain Family
ETRAMP

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TIGR01495: ETRAMP 
Plasmodium ring stage membrane protein ETRAMP
This model describes a family of proteins from the malaria parasite Plasmodium falciparum, several of which have been shown to be expressed specifically in the ring stage as well as the rident parasite Plasmodium yoelii. A homolog from Plasmodium chabaudi was localized to the parasitophorous vacuole membrane. Members have an initial hydrophobic, Phe/Tyr-rich stretch long enough to span the membrane, a highly charged region rich in Lys, a second putative transmembrane region, and a second highly charged, low complexity sequence region. Some members have up to 100 residues of additional C-terminal sequence. These genes have been shown to be found in the sub-telomeric regions of both P. falciparum and P. yoelii chromosomes
Statistics
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PSSM-Id: 130559
View PSSM: TIGR01495
Aligned: 10 rows
Threshold Bit Score: 59.6554
Threshold Setting Gi: 124505597
Created: 8-Oct-2014
Updated: 2-Oct-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
TIGR:PFB0120w   1 MKLSKILYFFAALLALNFIAPRDYNS----MVEAKp-----------aKKLTPAERKK-RNQN--IMIYS-SIASAVALL 61  Plasmodium fal...
CAB92935        1 MKVTRILYFVFFIFALNFIAPNNEHNg---YVEAK-------------KKLTPAEIKK-RNQK--LMMYS-AIASGVAVL 60  Plasmodium fal...
CAB92933        1 MKVSNILFFFFAIIAVKLVYPGYVAAg---SNNNAgap--------tgKKLTDIEKKK-RNKN--IVLYS-SLASALALL 65  Plasmodium fal...
XP_001347716    1 MKITKIFYFFAALLALNFIAPNYF-Ng---YVEAK-------------KALTPAEKKK-RNQQ--IMLIS-GITSALALL 59  Plasmodium fal...
ETW42518        1 MKVGKIFFLLNILVVCHFIISCLCRNg---QTTRGnll--------alKAIEQDLQQK-KNRKrnLILYSlGSAALIAAL 68  Plasmodium fal...
XP_001350795    1 MKLFKILYLIAALLAINLIAPSVCNEnvegKKKKKgc---------plRNFNFQEFRK-KHHK--AILIS-SVVSAIALL 67  Plasmodium fal...
XP_001352225    1 MRILKVLTLLVFLLCINVFSPCYTKNg---FLSRIkd---------rfTKFEKKMKDK-ENKK--KLLIS-ASIVGLSLL 64  Plasmodium fal...
XP_001347304    1 MKISKILFFFVAIIAVKLFIPGYVL-----GGSSGsg---------gvKKLTDAQKKK---KN--IIIFS-SVASVLAAL 60  Plasmodium fal...
XP_001349750    1 MKVSKLVLFAHIFFIINILCQYICLNa---SKVNKkgkiaeekkrkniKNIDKAIEEHnKRKK--LIYYS-LIASGAIAS 74  Plasmodium fal...
XP_001351540    1 MKLSNLFYVFALLISMNVFVPGFMNVl--gKNVNVdsi--------vmSKIDEMQKKK-QQQK--IIMIS-TVVTGLALL 66  Plasmodium fal...
TIGR:PFB0120w  62 IGGAVGLGIHLHKNNKGDNKK 82  Plasmodium falciparum 3D7
CAB92935       61 LGASIGLGVHFSKKKSPKKKV 81  Plasmodium falciparum 3D7
CAB92933       66 VGTGVGLGFYYKNKNDKGEKE 86  Plasmodium falciparum 3D7
XP_001347716   60 IGAGVGLGIHYKNKNNGDEKK 80  Plasmodium falciparum 3D7
ETW42518       69 VVTGIGLNMYMKKKNVDSEVQ 89  Plasmodium falciparum NF135/5.C10
XP_001350795   68 FGTAYGIGLHLNNKTFIKSIL 88  Plasmodium falciparum 3D7
XP_001352225   65 TNLIVGFAYYNYRKNQRNQAL 85  Plasmodium falciparum 3D7
XP_001347304   61 IGAGVGFGIYYKNHKSDNKDE 81  Plasmodium falciparum 3D7
XP_001349750   75 VAAILGLGYYGYKKSREDDLY 95  Plasmodium falciparum 3D7
XP_001351540   67 LGSALGFGYLSKSNKKPEVSG 87  Plasmodium falciparum 3D7
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