Conserved Protein Domain Family
recD
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TIGR01447: recD 
exodeoxyribonuclease V, alpha subunit
This family describes the exodeoxyribonuclease V alpha subunit, RecD. RecD is part of a RecBCD complex. A related family in the Gram-positive bacteria separates in a phylogenetic tree, has an additional N-terminal extension of about 200 residues, and is not supported as a member of a RecBCD complex by neighboring genes. The related family is consequently described by a different model. [DNA metabolism, DNA replication, recombination, and repair]
Links
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Statistics
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PSSM-Id: 273631
Aligned: 9 rows
Threshold Bit Score: 542.814
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
WP_003114993  34 LDLWVARGWLRALDRAFVAF------------LVELQPQ---ADPRVLLAAALTSHQLGHGHVCLDLEATVGAPd-AALS 97  Pseudomonas aer...
WP_003898535  78 VRAFNQAGVLDVSDVHVAQR------------LCALAGE---SDERVALAVAVAVRALRAGSVCVDLLSIARVAghDDLP 142 Mycobacterium t...
WP_002557219  10 FLKDKNKKFLTPELKLYEIIellninkkncykAQTLARSt--NNENIVIFLIFLFNYFDKGHLRADINLLAKDIqnTIIF 87  Lyme disease sp...
WP_010229142  11 LQSLLAQHILLPFDLVFAQ--------------KHLAQTs-sSNREAEAFLVVASALLRCGYPYFTIHKATISPtlPGIS 75  Chlamydia murid...
WP_010892272   9 LEDLVHQQVISPLDIAFAS--------------KHISs----DFEESFVFLAVSSALWRYGHPFLSLEENRIRPslGGIS 70  Chlamydia pneum...
WP_010896127   5 LKKAVKLKIIRPIDFYFS---------------QFIAQK----NNIVMLVAACVSYESSRGYISLPIKYFEKHYffSSSN 65  Buchnera aphidi...
WP_010906703   5 LKELKQHKVISEGDYYFAQLiad-------kqPDELPRE---QKNLAILLAALCSYSYQQGNTCLFLEKGLESNyfNLAY 74  Pasteurella mul...
WP_000971704   9 AKRLLAQGALRPLDVQFARFig---------kQAVLAGHnaaESELLSVLSAALSAELGRGHICLPLCDAQGNRcdLAAL 79  Vibrio cholerae
WP_010892955   4 LAALNQAGVLRTLDDALARS------------LCRLDPK---TPDKVAAAAALASMAVAHGHAGVDLAHPGLLAg-EMFD 67  Xylella fastidiosa

WP_003114993  98 LPPEgdegrdvllp-sqllhgvrlDAWREALAASPLVEVvderPg----------dPEPsetatsPLv------LCAQRL 160 Pseudomonas aer...
WP_003898535 143 WPDP--------------------ADWLAAVRASPLLAD----P------------PVL------HL-------YDDRLL 173 Mycobacterium t...
WP_002557219  88 TKDNlektnksynklikilkgletFGNLETIKNIVLLLK----KnnilmefnklkiTTP------LIl------ENNIYI 151 Lyme disease sp...
WP_010229142  76 NRLL--------------------FQWFQALPSDVKATL----Fe-----------------------------VCDDKI 102 Chlamydia murid...
WP_010892272  71 ETDL--------------------YRGFHNLPKEVRDKL----Fv-----------------------------VVSGRL 97  Chlamydia pneum...
WP_010896127  66 EVFIkkilt----------llekkINWPVELLKHASIGN----Gg-----------TST------Pl------vLHKKKI 108 Buchnera aphidi...
WP_010906703  75 RTAEqhyl-------------hiiQEKIAFLPIECWQSS----Ladh------iafTAT------PLekvaplvFQFNAL 125 Pasteurella mul...
WP_000971704  80 IGLYgeaslqh-------serwlaVDWQALLQASPLVGQ----Qg----------eAVP------Lm-------FDGSRL 125 Vibrio cholerae
WP_010892955  68 WPSA--------------------ADWVHLLRASRWVAE----Pseg-------eaPAP------TGqp---lvLEQGVL 107 Xylella fastidiosa

WP_003114993 161 YLRRYWRHELEIALALRERLGRQaPLAAdlA------------------------------------------------- 191 Pseudomonas aer...
WP_003898535 174 YLDRYWREEEQVCADLLALLTSR-RPAG--V------------------------------------------------- 201 Mycobacterium t...
WP_002557219 152 YTQKNYREEEELIKQIIKRLENHkSELN--D------------------------------------------------- 180 Lyme disease sp...
WP_010229142 103 YLRSLFLLREKVFQKLHTLAEAVpRTSL---------------------------------------------------- 130 Chlamydia murid...
WP_010892272  98 YLRSLYTIRSKLLDKLSLLCSATpNYFP---------------------------------------------------- 125 Chlamydia pneum...
WP_010896127 109 YLYKMWKSESNIFNYLYTKNKKNkINQKkcS------------------------------------------------- 139 Buchnera aphidi...
WP_010906703 126 YFYRIWQDEYRVAHYLQRAVQRGaETAPiaYeq----------------------------------------------- 158 Pasteurella mul...
WP_000971704 126 YLHRYWHYEKQLAARLTELAAPQrLSPAelAnlrerlntlfardylglwqalqqkplssveriqllndrldvvesdaldw 205 Vibrio cholerae
WP_010892955 108 YLRRYREYERRLAIGLRRIAAARlPPAE--S------------------------------------------------- 136 Xylella fastidiosa

WP_003114993 192 ----------------PRLAALFAQAPTEDgqrvtdWQk------lACALAARGYFSLITGGPGTGKTTTVVRLLGLLQA 249 Pseudomonas aer...
WP_003898535 202 ----------------PDLRRLFPTGFDEQ------RR--------AAEIALSQGVTVLTGGPGTGKTTTVARLLALVAE 251 Mycobacterium t...
WP_002557219 181 ----------------NKIQNIISNLNTNN------LNkeq---itSVRKALKSNFFLLSGGPGTGKTTTVNYILKAINK 235 Lyme disease sp...
WP_010229142 131 -----------------IFENVSQLSEEQNa---------------VLGNVLNSCFSLVCGGPGTGKTFLAVQMIRLILS 178 Chlamydia murid...
WP_010892272 126 -----------------PSIDSSILSEEQNf---------------IFNKITQGCFSIVSGGPGTGKTFLAAQLILSLVK 173 Chlamydia pneum...
WP_010896127 140 ----------------KILENLFPQKNMSF------QKi-------AVALTLINNITFIIGGPGTGKTTTILKIIIALIK 190 Buchnera aphidi...
WP_010906703 159 --------------iqAILMHYFPAVQQIE------GVnwq---kvAVATALKQPFCLITGGPGTGKTTTVARLLLALQT 215 Pasteurella mul...
WP_000971704 206 paieavvekaqraadlQALEQLIPLTHCLN------WQk------vAAAVALTRRFAVISGGPGTGKTTTVTKLLAALIS 273 Vibrio cholerae
WP_010892955 137 ----------------AAVATVFAALFPQA-------RagqdrqasAAALALQRALLLVTGGPGTGKTTTIARLLLLRVA 193 Xylella fastidiosa

WP_003114993 250 PAVAAGQ--PlR--IRLAAPTGKAAARLSESIGQQVRALPLA-----EDVLQAIPaeVTTLHRLLGSRP-DtRHFRHHRD 319 Pseudomonas aer...
WP_003898535 252 QAELAGE--P-RprIALAAPTGKAAARLAEAVRREMAKLDATd----RARLGDLH--AVTLHRLLGAKP-G-ARFRQDRQ 320 Mycobacterium t...
WP_002557219 236 TLNNKKK--G-L--VAITAPTGKASLRLQTSIDYSFKNL---------------EieCNTIQKLLGIKF-InKKNLYDEE 294 Lyme disease sp...
WP_010229142 179 QIPS-----A-Q--IVVASPTGKAAAHLHSVLSSQE--------------IIGASveVVTIHKFLKDVN---------NG 227 Chlamydia murid...
WP_010892272 174 QQPK-----L-R--IAIVSPTGKATSHIRQILMKYN--------------IFDDMvlMQTVHHFLQEYA---------YR 222 Chlamydia pneum...
WP_010896127 191 SSKKS----I-K--IQLSAPTGKATTHLNEILKNNIFDLYFS-----EKEKCSLPstATTIHQLLGIQKiSqKSFFN-KS 257 Buchnera aphidi...
WP_010906703 216 LSACQ----L-K--IKLVAPTGKAAARLTESINGALTRLAQEnmaisADLIASIPttAQTLHRLLGIRF-FeETPTFHPN 287 Pasteurella mul...
WP_000971704 274 QSMAQGKv-P-E--IKLIAPTGKAAARLTESMGKAVSQLAIE-----PEIAAAIPssSSTIHRLLGAIP-GsAEFRHHTR 343 Vibrio cholerae
WP_010892955 194 QARQQGQasL-R--IALAAPTGRAAERMAESLRAAAGYVSAAgg--dAALFAALPsgASTVHRLLGVIP-DtPRFRHCED 267 Xylella fastidiosa

WP_003114993 320 NPLALDVLVVDEASMIDLEMMASLLDALPPQAR--------LILLGDKDQLASVEAGAVLGDLCRDAEegwysaetrawl 391 Pseudomonas aer...
WP_003898535 321 NRLPHNVIVVDETSMVSLTLMARLAEAVRPGAR--------LILVGDADQLASVEAGAVLADLVDGFS------------ 380 Mycobacterium t...
WP_002557219 295 NQLNFDVIIIDEASMVDAHTFLKLLKATPITTK--------LIMVGDKNQLPSVNEGNVYSSLLGIQKi----------- 355 Lyme disease sp...
WP_010229142 228 RS-PVDLLLIDEGSMVTMNLLHGLIKTIRGEIRegklfadrMVIFGDVNQLPPIGIG-VGNPFHELVS------------ 293 Chlamydia murid...
WP_010892272 223 RYNSIDVLLVDEGSMVTFDLLYSLVQTLQGYEKdkklytssLIILGDTNQLPPIGIG-VGNPLQDLIG------------ 289 Chlamydia pneum...
WP_010896127 258 NCLDLDVLIIDEISMVDILMMEKILSSISKNTK--------LIFIGDHNQLGPIESGSILRKICYYANdgysfksmisie 329 Buchnera aphidi...
WP_010906703 288 NPLPLDVLVVDEASMIDLPLMAKLLQALKPNTK--------LILLGDENQLSPVEAGEMLGALSEFSQhayspaltqylk 359 Pasteurella mul...
WP_000971704 344 NPLHLDLLVVDEASMVDLPLMVKLVEALPKHAR--------LILLGDKDQLASVEAGAVLGDICTFLNqgygheqgaqla 415 Vibrio cholerae
WP_010892955 268 NPLPYDVIVVDEASMMDLPLMCKLVDAVADGTQ--------LILLGDPDQLPSVEAGDVLAGILAAAGsgevldaadaqa 339 Xylella fastidiosa

WP_003114993 392 qr--vsgetwqglregssQAHPLAqqTVMLRHSRRFGAssGIGRLARLVNrqqAGDARALLDsppa---------dlfDL 460 Pseudomonas aer...
WP_003898535 381 ------------------VRDDAL--VAQLRTSHRFGK--VIGTLAEAIR---AGDGDAVLG----------------LL 419 Mycobacterium t...
WP_002557219 356 ----------------------nSdnVEDLKENFRSNK--EINLLSKAIYkedSTLICKYIN----------------NN 395 Lyme disease sp...
WP_010229142 294 --------------------E-FTqqAFFLSTSHRAKHk-ELQELAKSVL------------------------------ 321 Chlamydia murid...
WP_010892272 290 --------------------Y-FHenTFFLKTSHRAKTg-VVDQLTQSVL------------------------------ 317 Chlamydia pneum...
WP_010896127 330 k----ltqyklckkinkkTTNFISdnICVLNKNYRFNKnsGIYTLSNAIFkkkTRIIESLFD------------------ 387 Buchnera aphidi...
WP_010906703 360 -------avadielissdQGSPLRdhLCRLHHSHRFSGdsGIGQLAQAIN---QGNVEVSWNafthfndiemvdfdqvAL 429 Pasteurella mul...
WP_000971704 416 e----ltgfatlrqtaskTVNPVAdcLCMLQKSYRFDArsGIGQLAKAIN---SGSPARVEAv---------------WQ 473 Vibrio cholerae
WP_010892955 340 lapllgapsaavvaechvVRGGLHghRMHLQHSHRQGEdlALAPLAEAVR---LGDATAVLG----------------ML 400 Xylella fastidiosa

WP_003114993 461 RLRGERdAAFARlFVDGHPQAPGTPYGYRHYLQRLAegrpaaglALEDgaw------erwAQSVLTAFDAFRLLCALRRG 534 Pseudomonas aer...
WP_003898535 420 RSGEER-IEFVD-DEDPAPRLRAVLVPHALRLREAA--------LLGA------------SDVALATLDEHRLLCAHRDG 477 Mycobacterium t...
WP_002557219 396 KNIQLKeIEKINsKKDLIEYTNNLYRKIPTFNLKLL--------KESK------------IETILETLLENIILSSKNFG 455 Lyme disease sp...
WP_010229142 322 H-KQPIpFQPLPsRKEAIRRLSDAFVQT--AKAG----------------------------------ISLCALTPMRQG 364 Chlamydia murid...
WP_010892272 318 R-GEMIsFSPLPsISSAIEVLKNRFVKS--LRQSE---------------------------------ARLCVLTPMRHG 361 Chlamydia pneum...
WP_010896127 388 NSIKNIfFYETNsSEQYKKMIKNICLNYEDFWEKIYkk--------------------atMKEIIESFQNYQVLCILHDG 447 Buchnera aphidi...
WP_010906703 430 LKGDNPsLYSQAcAALVVKSAVEKYTDYLVKLKALQqq----spILNEq----------qVGEIFVLFNAVRFLTALRVG 495 Pasteurella mul...
WP_000971704 474 QSFSDIeH-FALsGEHYQQLLQTLVQAYRPYLSLLN--------QPTEqfestqqsmltlAKSALDAFSRCRLLCALREG 544 Vibrio cholerae
WP_010892955 401 RRGTLRgVQFHEgVLDPCVGAGQVLLAH---WRALA--------ALSD------------PVQALAVARRLRLLTALREG 457 Xylella fastidiosa

WP_003114993 535 PWGVEGLNQRVAAELL----RLGLIEADHGWYEGRPVLVTRNDYSLGLMNGDIGIALRLPERnddgslrfaLRVAFPRND 610 Pseudomonas aer...
WP_003898535 478 PTGVLHWNRRVQAWLA----EETGQPPWTPWYAGRPLLVTANDYGLRVYNGDTGVVLAGPTG---------LRAVISGAS 544 Mycobacterium t...
WP_002557219 456 KFGTKTLNEIIKTYLK----KTY------GSFIGQIIMITKTDYKNKLFNGERGVIFNENFK---------FYALFQRKD 516 Lyme disease sp...
WP_010229142 365 PWGFLQLNRLLFNEMQe------KHPQ-----APVPIIVTERYETWGLTNGDTGILDP-------------LTQQLHFMN 420 Chlamydia murid...
WP_010892272 362 PWGVLNLNTMIHQRLAr------SDPD-----LRIPIMVTSRYETWGLFNGDTGLLCL-------------KTQKLHFPQ 417 Chlamydia pneum...
WP_010896127 448 LFGVNIINKKLEENMYkkniIKYFYIDGEEWYIGKPIMIINNNRALNVSNGNIGITNINKNGi--------LQVSFLKEN 519 Buchnera aphidi...
WP_010906703 496 ELGVEQLNQKIAQRLQq--kGLLDFKHERDWYLGKPIMIQQNDRHIGLYNGDIGLFLG---Qg--------K-VWFEQGQ 561 Pasteurella mul...
WP_000971704 545 DFGVMGLNTRIERALNa---HKLIKTQEEIWYHGRPIMVTRNDHGLGLYNGDIGLCMRDRDDdq-----grLKVYFELPD 616 Vibrio cholerae
WP_010892955 458 PQGAAGINARIERLLG----GGGVDG----YFHGRLLLMTETSPRQRLFNGDIGVCLRDEDGt--------MWAWFSGAG 521 Xylella fastidiosa

WP_003114993 611 GSggvRFVLPSRLVEVDTVFAMTVHKSQGSEFAHTALVLPDALNPVLTKELVYTGITRARDWFSLVESLPgVFEEAVRRK 690 Pseudomonas aer...
WP_003898535 545 GP---LDVATGRLGDVETMHAMTIHKSQGSQVDEVTVLMPQEDSRLLTRELLYTAVTRAKRKVRVVGSEA-SVRAAIARR 620 Mycobacterium t...
WP_002557219 517 EKy--KKINLDLLTNYEFSFATTIHKSQGSEYKHIKVILEN--NPFLTKELMYTAITRAKDSLEIISNKE-Tiiklskks 591 Lyme disease sp...
WP_010229142 421 G----EILRKEDFPYYSYNYVMSVHKSQGSEYDRVIVILPKG-SEVFDSAILYTAITRTKQCVEIWADKE-TLDMVISKK 494 Chlamydia murid...
WP_010892272 418 H----EPIDSRALSQYVYNYVMSVHKSQGSEYDEVIVIIPKG-SEVFGVSILYTAITRAKYRVSVWGDPE-TLHKIIKKS 491 Chlamydia pneum...
WP_010896127 520 NTi--NNIPVKILRNYKTAWAITVHKSQGSEFMNTALILPNFNSHILNKDTLYTGITRSRKILSIFSDKKiFLNTIFKNT 597 Buchnera aphidi...
WP_010906703 562 GHy--KTVLASRVPNYETAFVMTVHKSQGSEFAHTCLVLPTEPNPILSRELIYTGVTRAKQQLTVFSSAE-IWKSAVKNP 638 Pasteurella mul...
WP_000971704 617 GSi--KAVLPSRVPQHETAYAMTIHKSQGSEFDLTLLILPPDYSPILTRELVYTGITRAKKQLKLYCDNK-VLQRAIKVK 693 Vibrio cholerae
WP_010892955 522 GEg-vRAFAPATLPAHESAFAMTVHKAQGSEFDTVWLQLPRQESRVLSRELIYTGLTRARHALHVAGSES-VLCAALARQ 599 Xylella fastidiosa

WP_003114993 691 VRRLS 695 Pseudomonas aeruginosa
WP_003898535 621 AVRAS 625 Mycobacterium tuberculosis
WP_002557219 592 skrds 596 Lyme disease spirochete
WP_010229142 495 GRY-- 497 Chlamydia muridarum
WP_010892272 492 NY--- 493 Chlamydia pneumoniae
WP_010896127 598 NKILF 602 Buchnera aphidicola
WP_010906703 639 VKRQS 643 Pasteurella multocida
WP_000971704 694 TQRAS 698 Vibrio cholerae
WP_010892955 600 AVRVS 604 Xylella fastidiosa
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