Conserved Protein Domain Family
TFS_arch

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TIGR01384: TFS_arch 
transcription factor S, archaeal
This model describes archaeal transcription factor S, a protein related in size and sequence to certain eukaryotic RNA polymerase small subunits, and in sequence and function to the much larger eukaryotic transcription factor IIS (TFIIS). Although originally suggested to be a subunit of the archaeal RNA polymerase, it elutes separately from active polymerase in gel filtration experiments and acts, like TFIIs, as an induction factor for RNA cleavage by RNA polymerase. There has been an apparent duplication event in the Halobacteriaceae lineage (Haloarcula, Haloferax, Haloquadratum, Halobacterium and Natromonas). There appears to be a separate duplication in Methanosphaera stadtmanae. [Transcription, Transcription factors]
Statistics
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PSSM-Id: 130451
View PSSM: TIGR01384
Aligned: 5 rows
Threshold Bit Score: 138.82
Threshold Setting Gi: 14324969
Created: 8-Oct-2014
Updated: 2-Oct-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_010868495   3 KFCPKCGSIMIPdkKRG----VFVCRRCGYEEP--INPE--DAkaYKRTEEVKHKPDEGVIVVEQDF-STLPTaK----V 69  Pyrococcus abyssi
WP_010870659   3 KFCPKCNNLMLP--KDG----KLKCAVCGYEEE--TTAEgsKE--YEYKEHLENKKEKITVIESEGL-ETLPTtR----I 67  Methanocaldococ...
O27369         2 EFCPKCGAVMFP--SEG----KFKC-QCGYEKDitDKLK--DK--YRVSEEVE--AKETIIFTGDDV-NTLPTtR----V 63  Methanothermoba...
BAB59895       7 MFCPKCGSLMTP--VNG----RYVCPSCGYEVS--KK-K--ED--LKIVNKSNDK--ETIMIREEVSaEPLDS-D----A 66  Thermoplasma vo...
WP_010922932   5 KFCPKCNSMMVP--KKSngknVYRCTKCGYEKE--V-PE--TT--IVVTSKVKHSIKEKTLVLEEEE-MPSGA-QkikgV 73  Sulfolobus solf...
WP_010868495  70 TCPKCGYHEaWYWELQTRaG-DEPSTIFYKCKRCGYVWRSYE 110 Pyrococcus abyssi
WP_010870659  68 ECPKCGHNEaYWWLQQTR-CaDEPETRFYKCKKCGHTWREYD 108 Methanocaldococcus jannaschii
O27369        64 ECPKCGNMEaFWWLQQTR-RaDESETRFFRCTRCKHTWREYD 104 Methanothermobacter thermautotrophicus str. Delta H
BAB59895      67 ICPRCHHKGaRYVLKQTR-SaDEPETKFYTCEECGYRWREY- 106 Thermoplasma volcanium GSS1
WP_010922932  74 LCPSCKNDEaYFWILQTR-RaDEPPTRFYKCTKCGKVWREYE 114 Sulfolobus solfataricus
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