3NDP,1ZAK


Conserved Protein Domain Family
adk

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TIGR01351: adk 
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adenylate kinase
Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ATP as a phosphate donor for AMP. Most members of this family are known or believed to be adenylate kinase. However, some members accept other nucleotide triphosphates as donors, may be unable to use ATP, and may fail to complement adenylate kinase mutants. An example of a nucleoside-triphosphate--adenylate kinase (EC 2.7.4.10) is SP|Q9UIJ7, a GTP:AMP phosphotransferase. This family is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]
Statistics
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PSSM-Id: 273569
Aligned: 33 rows
Threshold Bit Score: 220.569
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3NDP_A         7 RAVILGPPGSGKGTVCQRIAQNFGLQHLSSGHFLRENIKAS-TEVGEMAKQy-IEKSLLVPDHVITRLMMSELeNRRGQ- 83  human
O51378         2 GLVFLGPPGSGKGTISKIISNEFKYQHISTGDLFRENILNS-TALGQEIKKi-VERGELVPDLITIKIVEDKIkAIKk-- 77  Borrelia burgdo...
O52352         3 RLIFLGAPGTGKGTISSYLKEQHGFFHISSGDLFRFYAKEEkTALAEEIKSy-INNGLYVPDELTNRTVADFYhKNQs-- 79  Mycoplasma gall...
P47417         7 KFIILGPPGAGKGTVCKLLSKTTKLVHIASGDLFREAIKNQ-SVIGRKIAAi-ISQGGYVDDATTNQLVYEYItTNPl-- 82  Mycoplasma geni...
Q50299         6 KFLFLGAPGVGKGTLAKQVANTTGLFHLSTGDIFRSVMQEQ-GALSQTLAHy-MNQGLYVPDELTNQTFWHFVtTHQNEl 83  Mycoplasma pneu...
P10251         2 NIMLLGAPGCGKGTQAEQLVNKLNFIQVSTGDLMRKEISLN-TTLGLKCQEy-MNAGKYVPDQIVNQIVNq---FLQYn- 75  Mycoplasma capr...
Q9PQP0         2 KILLIGPPGSGKGSVSELLTKNNTLKHVSTGNLFRAILKED-SELARKIKEinVSGGKLVPDEITNQVAKSAIdELIKn- 79  Ureaplasma parv...
AAC46846      29 KLVLLGAPGAGKGTQAKHLVSKYSLKHISPGNLLREEMNRN-SPITAQIKDy-VSKGQLVPDSIVIKLIENHIaTIG--- 103 Giardia intesti...
WP_010882896   6 vFIIMGPPGSGKGTQSQYLANRIGLPHISTGDLLRAIIREG-TPNGLKAKAy-LDKGAFVPSDFVWEILKEKLqSqac-- 81  Chlamydia pneum...
WP_004599187   2 IVIFLGPPGAGKGTQGKKIAKKIDLPHIAVGDIFRTIIKTS-TSEAELINNy-VKQGALIPNEIVNQVIKVFLlSSKy-- 77  Rickettsia prow...
3NDP_A        84 H--WLLDGFPRTLGQAEALDKICE-----VDLVISLNIPF-ETLKDRLSRRWIHPPSGRVYNLDFNpph---vhGIDDVT 152 human
O51378        78 NkdFILDGFPRNICQAEALDKFLp-----NVKIINFLIDE-ELVIKRLSGRRICKSCNNIFNIYTLttk--kngICDVCG 149 Borrelia burgdo...
O52352        80 QdkIIFDGYPRTLNQCEYID--EIi---kFTHVILLQPTDwDMIINRLSLRRSCPQCKRIYNINSVdfkpkvanLCDLCK 154 Mycoplasma gall...
P47417        83 PngFILDGYPRTENQLDFLN--IKl---tIDMVFELVVSDlNKLITRIDNRVICNNCNSVYNLLFQkpl--venSCDQCS 155 Mycoplasma geni...
Q50299        84 HkgFILDGYPRTLNQLEFLQ--SKl---qLDQVFHLKLSDpQVLVARILNRLVCPSCGSVYNKQSKppl--kanQCDRCH 156 Mycoplasma pneu...
P10251        76 NdkLIFDGYPRTLEQAKSLEKMLDlynkkIDYVFYIDVNE-QILIKRITNRLVCPLCKASFNLETRkpk--qegLCDFDN 152 Mycoplasma capr...
Q9PQP0        80 EqsFILDGYPRTINQALALEQYCNl-----DYIFYLDIDH-QELMKRLTGRWMCPKCAGIYNIHFKkpq--vhgLCDNDQ 151 Ureaplasma parv...
AAC46846     104 DsnWLLDGFPRSESQAAALRASpd---lfPTHIVELKVDQ-EAVVQRLGGRRFDPITGNTYHIIYDp------pPPD--I 171 Giardia intesti...
WP_010882896  82 skgCIIDGFPRTLDQAHLLDSFLMdv-hsNYTVIFLEISE-DEILKRVCSRFLCPSCSRIYNTSQGh------tECPDCH 153 Chlamydia pneum...
WP_004599187  78 KngYILDGYPRNLEQAKFFEAFIQk---pQIKIIYFDVAD-ELLIKRVLGRYSCKNCGKIYNIHFLqpk--iehVCDVCS 151 Rickettsia prow...
3NDP_A       153 GEPLVqQEDDKPEAVAARPRQYKDVAKPVIELYKSRGVLHQf-----SGT--ETNKIWPYVYTLFS 211 human
O51378       150 GDLYQ-REDDKEECLKTRLKEYKLQTKPLIEFYSKCSRLNNv-----DASv-KIDEIKKKIIKIML 208 Borrelia burgdorferi B31
O52352       155 VELIH-RKDDDPSVVSTRINVYNEQTKPVIEYYKKKNLLHVv-----DANk-SFEELYKLVLEIVN 213 Mycoplasma gallisepticum str....
P47417       156 AKLVK-RSDDNKAVVKARMELYQQTIQPIHTYFFNKQLLVQi-----DCFl-PLEEQLKTIKQFIR 214 Mycoplasma genitalium G37
Q50299       157 ATLQA-RNDDTEAVILKRLTLYEDTVKPLIEAFTKQGILTVi-----EAQl-PLEQQVNLVQQLVH 215 Mycoplasma pneumoniae M129
P10251       153 TKLVK-RSDDSLDKVKIRLQTYKEQTLPLIDYFKTNSKFIEi-----KADnlSAEQVFNQIKGELK 212 Mycoplasma capricolum subsp. ...
Q9PQP0       152 ATLYQ-RADDHADAVSIRLDEYDKLTLPLIKHYETNPRFIKi-----NANq-PIEDVYKNINNYLK 210 Ureaplasma parvum serovar 3 s...
AAC46846     172 ADRVVvRTDDREDVIRERFRVYAENKDLVDKVFNHSVVSINcegqtiDEVslQLDRVLSMPSTIHP 237 Giardia intestinalis
WP_010882896 154 VPLIR-RSDDTPEIIKERLTKYQERTAPVIAYYDSLGKLCRv-----SSEn-KEDLVFEDILKCIY 212 Chlamydia pneumoniae
WP_004599187 152 SSVFDyRKDDNKEVIKKRIKVYKTETYPLIDYYKNSGNFYIv-----NANk-NEQEIENDIQKILK 211 Rickettsia prowazekii
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