1YGY


Conserved Protein Domain Family
PGDH

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TIGR01327: PGDH 
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D-3-phosphoglycerate dehydrogenase
This model represents a long form of D-3-phosphoglycerate dehydrogenase, the serA gene of one pathway of serine biosynthesis. Shorter forms, scoring between trusted and noise cutoff, include SerA from E. coli. [Amino acid biosynthesis, Serine family]
Statistics
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PSSM-Id: 273556
Aligned: 11 rows
Threshold Bit Score: 717.951
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1YGY_A         6 VVLIADKLAPSTVA-AL-G-DQv-EVrWVDGPDRDKLLaaVPEADALLVRSATTVDAEVLAAA-PKLKIVARAGVGLDNV 80  Mycobacterium t...
Q58424         3 KILVTDPLHEDAIK-IL-E-EVg-EVeVATGLTKEELLekIKDADVLVVRSGTKVTRDVIEKA-EKLKVIGRAGVGVDNI 77  Methanocaldococ...
O29445         2 KVLVAEPISEEAID-YM-R-KNglEVeVKTGMSREELIreVPKYEAIVVRSQTKVDAEVIQAA-KNLKIIGRAGVGVDNI 77  Archaeoglobus f...
O53243         5 VVLIADKLAPSTVA-AL-G-DQv-EVrWVDGPDRDKLLaaVPEADALLVRSATTVDAEVLAAA-PKLKIVARAGVGLDNV 79  Mycobacterium t...
WP_010881245   3 KVLITDPIAPEGIE-LLqK-DPevEVyNEPDISYEELLeiIKDFDAIITRSRTPVTKELLERA-EKLKVVGRAGVGVDNV 79  Aquifex aeolicus
WP_010872507  31 KVLVSDSIDQVGID-IL-K-QVa-QVdVKTGLSEAEIIdiVPEYDAIMLRSATKVTEKIIQAG-SQLKIIGRAGVGVDNI 105 Synechocystis s...
WP_000808849   5 NVLVADPISKDGIKaLL-D-HEqfNVdIQTGLSEEALIkiIPSYHALIVRSQTTVTENIINAA-DSLKVIARAGVGVDNI 81  Staphylococcus ...
WP_000285096   3 QVAICDPIHAKGIQ-IL-EaQKdiVLhDYSKCPKKELLekLTPMDALITRSMTPITSDFLKPL-THLKSIVRAGVGVDNI 79  Helicobacter py...
WP_010921048   5 RVLIADKLSPAAVE-IF-K-NRglAFdIKTGLSKDELIavIGDYDGIAIRSGAKLDKDVIAAA-NKLRVIARAGIGVDNV 80  Caulobacter vib...
WP_010887934  21 RVLICDEMNPGNLD-HEg-----fQIdYQGNLEREETLrrLPDYDALITRSRTKVDRELLDAAgPRLKVIGRGGVGVDNI 94  Deinococcus rad...
P35136         3 RVLVSDKMSNDGLQpLI-E-SDfiEI-VQKNVADAEDE--LHTFDALLVRSATKVTEDLFNKM-TSLKIVGRAGVGVDNI 76  Bacillus subtil...
1YGY_A        81 DVDAATARGVLVVNAPTSNIHSAAEHALALLLAASRQIPAADASLREHT-WKRSSFSGTEIFGKTVGVVGLGRIGQLVAQ 159 Mycobacterium t...
Q58424        78 DVEAATEKGIIVVNAPDASSISVAELTMGLMLAAARNIPQATASLKRGE-WDRKRFKGIELYGKTLGVIGLGRIGQQVVK 156 Methanocaldococ...
O29445        78 DINAATQRGIVVVNAPGGNTISTAEHAIALMLAAARKIPQADRSVKEGK-WERKKFMGIELRGKTAGVIGLGRVGFEVAK 156 Archaeoglobus f...
O53243        80 DVDAATARGVLVVNAPTSNIHSAAEHALALLLAASRQIPAADASLREHT-WKRSSFSGTEIFGKTVGVVGLGRIGQLVAQ 158 Mycobacterium t...
WP_010881245  80 DIEEATKRGILVVNTPGANTIGATELTMMHMLTIMRNGHKAHESMLNYK-WDRKKFMGEELYGRILGIIGLGNIGSQVAI 158 Aquifex aeolicus
WP_010872507 106 DVPAATRQGIVVVNSPEGNTIAAAEHALAMMMALARHIPDANKSVKESK-WERKQFIGTEVYKKTLGVVGLGKIGSHVAG 184 Synechocystis s...
WP_000808849  82 NINAATLKGILVINAPDGNTISATEHSLAMLLSMARNIPQAHQSLTNKE-WNRNAFKGTELYHKTLGVIGAGRIGLGVAK 160 Staphylococcus ...
WP_000285096  80 DLESCSQKGIVVMNIPTANTIAAVELTMAHLINAVRSFPCANDQIKHQRlWKREDWYGTELKNKKLGIIGFGNIGSRVGI 159 Helicobacter py...
WP_010921048  81 DIPAATAKGIVVMNTPFGNSITTAEHAIAMMFALARQIPAADVSTQGGK-WEKNRFMGVELYAKTLGLIGAGNIGGIVAD 159 Caulobacter vib...
WP_010887934  95 DLEYASRRGLLVLNAPESNNVSAAELAVMHLMAAARGLTRSDRKTRAGE-WDRK-FLGLELTDKTLGIVGLGRIGSIVAD 172 Deinococcus rad...
P35136        77 DIDEATKHGVIVINAPNGNTISTAEHTFAMISSLMRHIPQANISVKSRE-WNRTAYVGSELYGKTLGIVGLGRIGSEIAQ 155 Bacillus subtil...
1YGY_A       160 RIAAFGAYVVAYDPYVSPARAAQLGIElL-SLDDLLARADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNAARGGLVD 238 Mycobacterium t...
Q58424       157 RAKAFGMNIIGYDPYIPKEVAESMGVElVdDINELCKRADFITLHVPLTPKTRHIIGREQIALMKKNAIIVNCARGGLID 236 Methanocaldococ...
O29445       157 RCKALEMNVLAYDPFVSKERAEQIGVK-LvDFDTLLASSDVITVHVPRTKETIGLIGKGQFEKMKDGVIVVNAARGGIVD 235 Archaeoglobus f...
O53243       159 RIAAFGAYVVAYDPYVSPARAAQLGIElLs-LDDLLARADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNAARGGLVD 237 Mycobacterium t...
WP_010881245 159 RAKAFGMKVMAYDPYIPREKAEKLGVKlVdNLHDMLREIDVLTIHAPLTHETKNMIDEKEFEIMKDGVYIVNCARGGIIN 238 Aquifex aeolicus
WP_010872507 185 VAKAMGMKLLAYDPFISQERADQIGCTlV-DLDLLFSEADFITLHIPKTPETANLINAETLAKMKPTARIINCSRGGIID 263 Synechocystis s...
WP_000808849 161 RAQSFGMKILAFDPYLTDEKAKSLSITk-aTVDEIAQHSDFVTLHTPLTPKTKGLINADFFAKAKPSLQIINVARGGIID 239 Staphylococcus ...
WP_000285096 160 RAKAFEMEVLAYDPYIPSSKATDLGVIyTkNFEDIL-QCDMITIHTPKNKETINMIGAKEIERMKKGVILLNCARGGLYN 238 Helicobacter py...
WP_010921048 160 RALGLKMKVVAYDPFLSPERAVEMGVEkVe-LDELLARADVITLHTPLTDKTRNILSAENLAKTKKGVMIVNCARGGLVD 238 Caulobacter vib...
WP_010887934 173 RAQGLHMNVVAYDPYVPENKFERLGVQrAaSLDELLGQVDALTVHTPLTDETRGMIGERELALLKRDAIVVNAARGGIIE 252 Deinococcus rad...
P35136       156 RARAFGMTVHVFDPFLTEERAKKIGVN-SrTFEEVLESADIITVHTPLTKETKGLLNKETIAKTKKGVRLINCARGGIID 234 Bacillus subtil...
1YGY_A       239 EAALADAITGGHVRAAGLDVFATEPCT------DSPLFEL-AQVVVTPHLGASTAEAQDRAGTDVAESVRLALAGEFVPD 311 Mycobacterium t...
Q58424       237 EKALYEALKEGKIRAAALDVFEEEPPK------DNPLLTL-DNVIGTPHQGASTEEAQKAAGTIVAEQIKKVLRGELAEN 309 Methanocaldococ...
O29445       236 EAALYEAIKAGKVAAAALDVYEKEPPSp-----DNPLLKL-DNVVTTPHIAASTREAQLNVGMIIAEDIVNMAKGLPVRN 309 Archaeoglobus f...
O53243       238 EAALADAITGGHVRAAGLDVFATEPCT------DSPLFEL-AQVVVTPHLGASTAEAQDRAGTDVAESVRLALAGEFVPD 310 Mycobacterium t...
WP_010881245 239 EKALIKYMESGKIKGVALDVYSKEPPPpefideLKRLADK-VNISLSPHIGANTYESQRNVAVIVAQQVLKALKGQTVEY 317 Aquifex aeolicus
WP_010872507 264 EEALVTAIETAQIGGAALDVFAQEPLG------ESRLREF-SNVILTPHLGASTEEAQVNVAVDVAEQIRDVLLGLPARS 336 Synechocystis s...
WP_000808849 240 EKALIKALDEGQISRAAIDVFEHEPAT------DSPLVAH-DKIIVTPHLGASTVEAQEKVAISVSNEIIEILIDGTVTH 312 Staphylococcus ...
WP_000285096 239 EDALYEALETKKVRWLGIDVFSKEPGI------HNKLLDL-PNVYATPHIGANTLESQEEISKQAAQGVMESLRGSSHPH 311 Helicobacter py...
WP_010921048 239 EAALRKLLDEGHVGGAAFDVFTVEPAK------ENPLFGS-DKVVATPHLGASTNEAQENVALQVAEQVSDYLLTGAVTN 311 Caulobacter vib...
WP_010887934 253 EQALVNALHAGHLFAAGVDVFVDEPPT------AEHIFLGaPNLGITAHLGANTREAQERVGAEIVSRVLDALHGDVSKG 326 Deinococcus rad...
P35136       235 EAALLEALENGHVAGAALDVFEVEPPV------DNKLVDH-PLVIATPHLGASTKEAQLNVAAQVSEEVLQFAKGLPVMS 307 Bacillus subtil...
1YGY_A       312 AVNVGG--GVVNEE-VAPWLDLVRKLGVLAGVLSDELPVSLSVQVRGELAAE-EvEVLRLSALRGLFSAVIEDAVTFVNA 387 Mycobacterium t...
Q58424       310 VVNMPNipQEKLGK-LKPYMLLAEMLGNIVMQVLDGSVNRVELIYSGELAKE-KtDLIKRAFLKGLLSPILLAGINLVNA 387 Methanocaldococ...
O29445       310 AVNLPSiePSDFEF-MMPFLTLAEKMGKIASVRLGGAIRKVKVTCSGKLATK-NtEFVTRALLKGLFEPILSNEINLVSA 387 Archaeoglobus f...
O53243       311 AVNVGG--GVVNEE-VAPWLDLVRKLGVLAGVLSDELPVSLSVQVRGELAAE-EvEVLRLSALRGLFSAVIEDAVTFVNA 386 Mycobacterium t...
WP_010881245 318 AVNAPFpdLSVLTL-IKPYLDLAEKLGKFLVQWTEEGIREVHIEVRGDIAEY-F-QPISSAVLKGILEEVVDFPVNIINA 394 Aquifex aeolicus
WP_010872507 337 AVNIPGltPDVMEK-LRPYLKLAETLGTLVGQLAGGRIDRLTVCLQGDLAEYtNsQPLVVAAIKGLLSQALRERVNYVNA 415 Synechocystis s...
WP_000808849 313 AVNAPKmdLSNIDDtVKSFINLSQTVGELAIQLMYNAPSSIKITYGGDLASI-DsSLLTRTIITHILKDDLGPEVNIINA 391 Staphylococcus ...
WP_000285096 312 ALNLPMqaFDAS---AKAYLNLAQKLGYFSSQIHKGVCQKIELSLCGEINQF-K-DALVAFMLVGVLKPVVGDKINYINA 386 Helicobacter py...
WP_010921048 312 ALNSPSitAEEAPK-LKPFVALAEKIGAFAGQMVDFGVKAIDIAYEGEVSNL-NvKPMTSAALAGVLKPMLA-EINMVSA 388 Caulobacter vib...
WP_010887934 327 AVNAPAldAKTMEQ-LGGYLDLGEKLGRILAQLLPGA-HEVEVTFRGEFPTD-PsPVVT-AVLMGYLSGSTDEHPNMINA 402 Deinococcus rad...
P35136       308 AINLPAmtKDEFAK-IKPYHQIAGKIGSLVSQCMKEPVQDVAIQYEGTIAKL-EtSFITKALLSGFLKPRVDSTVNEVNA 385 Bacillus subtil...
1YGY_A       388 PALAAERGVTAEICKASEsPNHRSVVDVRAVGADG----SvVTVSGTLYGPqlSQKIVQINGRHFDLRAQGINLIIHYVD 463 Mycobacterium t...
Q58424       388 PIIAKNRNINVVESSTSE-EKYGNAIKITAESDKK----K-FSIVGAIINN--KPVILEVDGYEVSFIPEGVLAIIKHID 459 Methanocaldococ...
O29445       388 KPVAVERGITIEESKVESvEHYESLLEVWVESNGK----E-MYLAGTCFGN--EYRILKIDVYNVNFVPKGHYIISLHED 460 Archaeoglobus f...
O53243       387 PALAAERGVTAEICKASEsPNHRSVVDVRAVGADGs---V-VTVSGTLYGPqlSQKIVQINGRHFDLRAQGINLIIHYVD 462 Mycobacterium t...
WP_010881245 395 FYVAKDRGIKVEELSSEEtPDFKHYIKVVVKADGK----E-KVVAGTVLEGq-IPRITEIDRYKVDIEPEGILLVFENKD 468 Aquifex aeolicus
WP_010872507 416 AIEAKERGIRVIETKDASvRDYSGSLHLKATGTMG----E-HSATGALLSNg-EIRITDVDEFPINVPPNNYMLFTLHRD 489 Synechocystis s...
WP_000808849 392 LMLLNQQQVTLNIENNKAeTGFSNYLEVELSNDSD----S-VKVGASVFTGf-GPRIVRINNFSVDLKPNQYQIVSYHND 465 Staphylococcus ...
WP_000285096 387 PFVAKERGIEIKVSLKESaSPYKNMLSLTLNAANG----T-ISVSGTVFEEd-ILKLTEIDGFHIDIEPKGKMLLFRNTD 460 Helicobacter py...
WP_010921048 389 PAIAKERGITVSESRQEVsPTYDSLMRVTITTEKG----K-RAFAGTVIAG--APRIVEVKGMELDAAFSPAMLYVNNLD 461 Caulobacter vib...
WP_010887934 403 RALARERGVTLSVREEEDsPDYQTEVIVRVLNRSGekerT-RKVGGTVFGk--SPRLTRLRDYRVELEPEGFILIASNLD 479 Deinococcus rad...
P35136       386 GGVAKERGISFSEKISSSeSGYDNCISVKVTGDRS----T-FTVTATYIPHf-GERIVEINGFNIDFYPTGHLVYIQHQD 459 Bacillus subtil...
1YGY_A       464 RPGALGKIGTLLGTAGVNIQAAQLSED--AEGPGATILLRLDQDVPDDVRTAIAAAVDAYKLEVVDL 528 Mycobacterium tuberculosis
Q58424       460 RPGTIGRVCITLGDYGINIASMQVGRK--EPGGESVMLLNLDHTVPEEVIEKIKEIPNIKDVAVINL 524 Methanocaldococcus jannaschi...
O29445       461 KPGVIGRVGTLFGRNNINIAGMIVGRSgdKPGGIQLMLLLVDDPPTPEVLEEMTKLDGIIDATYVEL 527 Archaeoglobus fulgidus DSM 4304
O53243       463 RPGALGKIGTLLGTAGVNIQAAQLSED--AEGPGATILLRLDQDVPDDVRTAIAAAVDAYKLEVVDL 527 Mycobacterium tuberculosis
WP_010881245 469 VPGVIGKIGSILGEANINIAGFRLGRE--KKGGIAIGILNLDEPASEEVLSRIKEIPEILFVKHIVL 533 Aquifex aeolicus
WP_010872507 490 MPGIIGKIGSLLGSFNVNIASMQVGRK--IVRGDAIMALSLDDPLPDGLLSEITKVAGIRDAYTVKL 554 Synechocystis sp. PCC 6803
WP_000808849 466 TPGMVGKTGALLGKYNINIASMTLGRT--EAGGDALMILSVDQPVSNNIIDELKQVGEYNQIFTTEL 530 Staphylococcus aureus
WP_000285096 461 IPGVIGSVGNAFARHGINIADFRLGRN--TQK-EALALIIVDEEVSLEVLEELKNIPACLSVHYVVI 524 Helicobacter pylori
WP_010921048 462 KPGFIGALGMLLGEAGVNIATFNLGRV--SADEDAIALVGVDQAPDAGLLAKIQALPHVKEARALTF 526 Caulobacter vibrioides
WP_010887934 480 KPGAVAKLSNLLGTWGINIAGMALGRS--EKGGQALFTLTLDDSLTPEQLQAIRDLDVIESAFLVRV 544 Deinococcus radiodurans
P35136       460 TTGVIGRVGRILGDNDINIATMQVGRK--EKGGEAIMMLSFDRHLEDKIVKELTNVPDIVSVKLIDL 524 Bacillus subtilis subsp. sub...
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