3NDN


Conserved Protein Domain Family
O_suc_HS_sulf
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TIGR01325: O_suc_HS_sulf 
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O-succinylhomoserine sulfhydrylase
This model describes O-succinylhomoserine sulfhydrylase, one of several related pyridoxal phosphate-dependent enzymes of cysteine and methionine metabolism. This enzyme is part of an alternative pathway of homocysteine biosynthesis, a step in methionine biosynthesis. [Amino acid biosynthesis, Aspartate family]
Links
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Statistics
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PSSM-Id: 188131
Aligned: 5 rows
Threshold Bit Score: 644.207
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3NDN_A        28 ATVGVRGGMLRSGFEETAEAMYLTSGYVYGSAAVAEKSFAGELDHYVYSRYGNPTVSVFEERLRLIEGAPAAFATASGMA 107 Mycobacterium t...
AHW76308      32 QTLAIRGGKEQTEYREHNQALFLTSSFMWDNAQHAADLFSKKIKGFTYTRTANPTTAAFEKRIAALEGAERAVATSTGMS 111 Neisseria menin...
WP_012640446  11 ATKLIRGGIARSQFMETAEALYLTQGFTYDSAEGADRRFAGEDPGFVYSRFNNPTVKMFEDRLALLEGAEVCRAQATGMA 90  Caulobacter vib...
WP_003113933  20 DTLAVRAGQRRTPEGEHGEALFTTSSYVFRTAADAAARFAGEVPGNVYSRYTNPTVRTFEERIAALEGAEQAVATASGMS 99  Pseudomonas
WP_003401927  20 ATVGVRGGMLRSGFEETAEAMYLTSGYVYGSAAVAEKSFAGELDHYVYSRYGNPTVSVFEERLRLIEGAPAAFATASGMA 99  Mycobacterium t...

3NDN_A       108 AVFTSLGALLGAGDRLVAARSLFGSCFVVCSEILPRWGVQTVFVDGDDLSQWERALSVPTQAVFFETPSNPMQSLVDIAA 187 Mycobacterium t...
AHW76308     112 AIQAAFFTFLQAGDHVISSRSLFGTTVGFINNIVTKFGIEVSHVSPTDINEWKAAVKANTKLLFLETPSNPLGEVADLEA 191 Neisseria menin...
WP_012640446  91 SIHAALMGLVRAGDHVVAGRALFGSCRWIVSEWLPRFGVETTFVDATDPKAWEAAMRPNTKAVLVETPSNPVLEITDIRA 170 Caulobacter vib...
WP_003113933 100 AILALVMSLCSSGDHVLVSRSVFGSTISLFDKYFKRFGIQVDYPPLSDLAAWEAACKPNTKLFFVESPSNPLAELVDIAA 179 Pseudomonas
WP_003401927 100 AVFTSLGALLGAGDRLVAARSLFGSCFVVCSEILPRWGVQTVFVDGDDLSQWERALSVPTQAVFFETPSNPMQSLVDIAA 179 Mycobacterium t...

3NDN_A       188 VTELAHAAGAKVVLDNVFATPLLQQGFPLGVDVVVYSGTXHIDGQGRVLGGAILGDREYIDGpVQKLMRHTGPAMSAFNA 267 Mycobacterium t...
AHW76308     192 LAELAHGIGALLVVDNSLLSPVGSQPLKHGADISVSSATKAIDGHGRVMGGVLAGSEELMAQ-VAVYCNSCGLAMSPFNA 270 Neisseria menin...
WP_012640446 171 VSELAHAVGAKVIVDNVFATPIFQKPLELGADVVVYSATKHIDGQGRVLGGAILTSEAINEEfYRDSLRHTGPSLSPFNA 250 Caulobacter vib...
WP_003113933 180 LAEIAHAKGALLAVDNCFCTPALQQPLKLGADVVIHSATKYIDGQGRGMGGVVAGRGEQMKE-VVGFLRTAGPTLSPFNA 258 Pseudomonas
WP_003401927 180 VTELAHAAGAKVVLDNVFATPLLQQGFPLGVDVVVYSGTKHIDGQGRVLGGAILGDREYIDGpVQKLMRHTGPAMSAFNA 259 Mycobacterium t...

3NDN_A       268 WVLLKGLETLAIRVQHSNASAQRIAEFLNGHPSVRWVRYPYLPSHPQYDLAKRQMSGGGTVVTFALD-CpedvaKQRAFE 346 Mycobacterium t...
AHW76308     271 WQLLSGVETLSLRMEKQFDNALKIAQWLQAQPQVQAVYYTGLPDHPQAELIRKQQNGGGIVIGFEVA-D-----QAAAWK 344 Neisseria menin...
WP_012640446 251 WVMLKGLETLDLRVRRQADSAFALANTIAEHKKVQTVLYPFRPDHPGHNVAKAQMTGGGTVIALDLG-S-----REAAFK 324 Caulobacter vib...
WP_003113933 259 WLFLKGLETLRIRMQAHSASALALAEWLERQPGIERVYYAGLPSHPQHELARRQQSGFGAVVSFDVKgG-----RDAAWR 333 Pseudomonas
WP_003401927 260 WVLLKGLETLAIRVQHSNASAQRIAEFLNGHPSVRWVRYPYLPSHPQYDLAKRQMSGGGTVVTFALD-CpedvaKQRAFE 338 Mycobacterium t...

3NDN_A       347 VLDKMRLIDISNNLGDAKSLVTHPATTTHRAMGPEGRAAIGLGDGVVRISVGLEDTDDLIADIDRAL 413 Mycobacterium tuberculosis
AHW76308     345 VVDGVELFSRTANLGDVRSTITHPWTTTHGRMQPEEKLAANIRPGLVRLSVGLEYVGDLIDDLKQAL 411 Neisseria meningitidis
WP_012640446 325 FLNALEIVDISNNLGDAKSMATHPPTTTHRSVPEAERPSLGVTEGGVRLSVGLESVEDLKRDVIRAL 391 Caulobacter vibrioides
WP_003113933 334 FIDATRMVSITTNLGDTKTTIAHPATTSHGRLSPEDRARAGIGDSLIRVAVGLEDLDDLKADMARGL 400 Pseudomonas
WP_003401927 339 VLDKMRLIDISNNLGDAKSLVTHPATTTHRAMGPEGRAAIGLGDGVVRISVGLEDTDDLIADIDRAL 405 Mycobacterium tuberculosis c...
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