2QRY


Conserved Protein Domain Family
sfuA

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TIGR01254: sfuA 
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ABC transporter periplasmic binding protein, thiB subfamily
The model describes thiamine ABC transporter, periplasmic protein in bacteria and archae. The protein belongs to the larger ABC transport system. It consists of at least three components: the thiamine binding periplasmic protein; an inner membrane permease; an ATP-binding subunit. It has been experimentally demonstrated that the mutants in the various steps in the de novo synthesis of the thiamine and the biologically active form, namely thiamine pyrophosphate can be exogenously supplemented with thiamine, thiamine monophosphate (TMP) or thiamine pyrophosphate (TPP). [Transport and binding proteins, Other]
Statistics
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PSSM-Id: 130321
View PSSM: TIGR01254
Aligned: 6 rows
Threshold Bit Score: 446.228
Threshold Setting Gi: 499189367
Created: 8-Oct-2014
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2QRY_A        22 KPVLTVYTYDSFAADWGPGPVVKKAFEa-dCncELKLVALEDGVSLLNRLRXEGKNSKADVVLGLDNNLLDAASKTGLFA 100 Escherichia coli
P44984        23 QQSVNVYSYDSFTSEWGAGPKVKQDFEkahPqcAINFTPFESVGVLLNRVRLEGKKTKADIVLGLDNFFLEQAEKTGIFA 102 Haemophilus inf...
WP_000671910  22 APTLTVYTYDSFAAEWGPAPAIEKAFEa-qCgcDLQFVALDDGVSILNRLRLEGSNSKADVVLGLDNNLIEEAKQTGLLA 100 Vibrio cholerae
P31550        19 KPVLTVYTYDSFAADWGPGPVVKKAFEa-dCncELKLVALEDGVSLLNRLRMEGKNSKADVVLGLDNNLLDAASKTGLFA 97  Escherichia col...
WP_002243927  20 QTEVRLAVHKSFSLPKGLIARFERANDa-----KVSIIQAGGANEMLNKLILSRANPIADAVYGLDNANIGKAREMGILA 94  Neisseria menin...
WP_010886907  19 qttltVITHDSFDVDKKLVAQFEAQNKa-----KVRFVKGGDAGELLNRLILTRRAPIADVVYGLDNSLLARAQQMNLLQ 93  Deinococcus rad...
2QRY_A       101 KSG-VAADAVNVPGGWNND-TFVPFDYGYFAFVYDKNKLKNP----PQSLKELVEsDQNWRVIYQDPRTSTPGLGLLLWX 174 Escherichia coli
P44984       103 PNN-VDLTQLDLPTKWANK-TFLPFDFGNYAFVYDKTKLQNP----PKSLKELVE-RQDLSVIYQDPRTSSVGRGLLVWM 175 Haemophilus inf...
WP_000671910 101 THS-VDTSKVTLPNGWSDN-TFVPYDYGYFAFVYNKEKLANP----PTSLKELVEkRDDLKVIYQDPRTSTPGQGLLLWM 174 Vibrio cholerae
P31550        98 KSG-VAADAVNVPGGWNND-TFVPFDYGYFAFVYDKNKLKNP----PQSLKELVEsDQNWRVIYQDPRTSTPGLGLLLWM 171 Escherichia col...
WP_002243927  95 AAQ-PESAPVAVG--LPSA---LAVDYGYVSINYDKKWFEGKklplPQTLQDLTRpEYKNLLVVPSPATSSPGLGFLMAN 168 Neisseria menin...
WP_010886907  94 PYRsPALGKVPAGYRLDDAgLLNTVDYGYVALNYDRAYFQKAglalPKSLDDLKKpEYARLTVVSSPATSSPGLAFLLAT 173 Deinococcus rad...
2QRY_A       175 QKVYg-DDAPQAWQKLAKKTVTVTKGWSEAYG---L---FLKGESDLVLSYTTSPAYHILEEK---------KDNYAAAN 238 Escherichia coli
P44984       176 NAVYpaDKIQSAWKELDKHTVTVGKGWSDTYG---A---FLKGEADLVLSYSTSPLYHQLFEK---------KDNYAATD 240 Haemophilus inf...
WP_000671910 175 KSVYg-DQAPQAWKQLASKTVTVTKGWSEAYS---M---FLGGEADLVLSYTTSPAYHLIAEN---------DARFATAN 238 Vibrio cholerae
P31550       172 QKVYg-DDAPQAWQKLAKKTVTVTKGWSEAYG---L---FLKGESDLVLSYTTSPAYHILEEK---------KDNYAAAN 235 Escherichia col...
WP_002243927 169 ISGLgeESAFKWWAQMRQNGVKVAKGWSEAYY---TdfsHNGGAYPLVVGYAASPAAEVYFSKgk-----ysEPPTGNLF 240 Neisseria menin...
WP_010886907 174 VNHYgeAGAWQWWKTARAGGLKVVRGWSDAYYkdfT---RAGGKYPIVLSYASSPAAEVFYADnydpaklpaQAPTANLL 250 Deinococcus rad...
2QRY_A       239 FSEGHYLQVEVAARTAASKQpELAQKFLQFXVSPAFQNAIPTGNWXYPVANVTLPAGFEKLTKPAt-tLEFTPAEVAAQR 317 Escherichia coli
P44984       241 FAEGHITQVELAARVANHPN-QCADDFMAFLISPTAQKHIVTANIMLPVIQGEIEPHFDALKVQQktqTSINPMVNTEQL 319 Haemophilus inf...
WP_000671910 239 FSEGHYLQVEVAAKVKSTKNgELADKFLQFILSNEFQSVIPTGNWMYPVTAVELPKGFDTLAVPTq-sLSFSAQEVAQMR 317 Vibrio cholerae
P31550       236 FSEGHYLQVEVAARTAASKQpELAQKFLQFMVSPAFQNAIPTGNWMYPVANVTLPAGFEKLTKPAt-tLEFTPAEVAAQR 314 Escherichia col...
WP_002243927 241 LKGGVFRQVEGAAVLKGAKQpELAAKLVQWLQSREVQQAVPSEMWVYPAVKNTRLPDVFRFAQAPthtTAPAQRDIDANQ 320 Neisseria menin...
WP_010886907 251 LPGSTWLQLEGVGVLKGAKQpALARKFVDFMLSPAVQADIPTRMWIYPAVSGTKLDPVFKFTQQPd--PAPVKASVTANP 328 Deinococcus rad...
2QRY_A       318 QAWISEW 324 Escherichia coli
P44984       320 KNWISTW 326 Haemophilus influenzae Rd KW20
WP_000671910 318 KPWIREW 324 Vibrio cholerae
P31550       315 QAWISEW 321 Escherichia coli K-12
WP_002243927 321 RGWVSRW 327 Neisseria meningitidis
WP_010886907 329 QRLVDAW 335 Deinococcus radiodurans
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