Conserved Protein Domain Family
pseudo_Pus10arc
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TIGR01213: pseudo_Pus10arc 
tRNA pseudouridine(54/55) synthase
Members of this family show twilight-zone similarity to several predicted RNA pseudouridine synthases. All trusted members of this family are archaeal. Several eukaryotic homologs lack N-terminal homology including two CXXC motifs. [Hypothetical proteins, Conserved]
Links
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Statistics
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PSSM-Id: 273504
Aligned: 6 rows
Threshold Bit Score: 533.568
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q60346        21 NYEILKKYPLCDRCFGRLYAKLLHTT-NTERGRALKLYKALELEAKIKKakekginyeeelellkalaksgvdeirledi 99  Methanocaldococ...
AAG20156       7 ARAVLAETPVCDACLGRCFAERSFGLsNAERGRALRTAVALADDEPYEE------------------------------- 55  Halobacterium s...
WP_010901702   3 QISELANYRLCKRCSGRIFAYHYHGIsNLERGEYLQFAIGCETGNPDFSf------------------------------ 52  Thermoplasma ac...
WP_010885053  22 AREILEKHPLCNHCLGRMFAKLGKGT-NEERGKAIRLILSMELNREVK-------------------------------- 68  Pyrococcus hori...
WP_010865826   9 ALRALSRYPLCDRCLGRLFARLGRGWsNRERGEAVKRVLVMELHRRVLEgdeaalktlvsaapnigevardvvehlspgs 88  Aeropyrum pernix
WP_010876935  10 LLEITES-RICLHCLGRHFVDLVEGPgNRLRGEKLQKKFSLKL------------------------------------- 51  Methanothermoba...

Q60346       100 eiEKENCPWCRGIFNKqkMEKLLNKAIELLKEY--DFDTFLIGTHIPEEIKDLEKEIETEF--M----ESIKQEFGREFG 171 Methanocaldococ...
AAG20156      56 --PEEPCWVCEGASGR--FDEFADLVVDAVADA--SFDTYQVGTQAPPLVEENEAMLRDLAglAedagEPFKSECNREVG 129 Halobacterium s...
WP_010901702  53 -vDSKNCDICHGIFDR--FDDIYDLVAKKVGDA--QYSTFLVGSVFPQDTIRMEEDIQKKFgsSg---ESIKKEFNREFG 124 Thermoplasma ac...
WP_010885053  69 --EPENCELCQGIFRR--MNELLDLVRNAVEDY--EFQTFQIGSRFPKDILEKEKKIWEEFgiTt--gEPINREFNRELG 140 Pyrococcus hori...
WP_010865826  89 yrEGGPCAVCGGRLESv-IASAVEEGYRLLRAY--DIERFVVGVRLERGVAMAEEEVKLAAgaGy--gESIKAEIRREVG 163 Aeropyrum pernix
WP_010876935  52 ---SGPCMICGDVFDR--IDEAAGMVKEKVDELglEYSSVLVGTRLPPKMVELDDEIRKRLgi---qtEGLKRDLNRELG 123 Methanothermoba...

Q60346       172 KMLAVRLDKAPDKEYPDIVVHINP-YTEEIYLQINPLFIKGRYRKLVRGIPQTRWPCRKc-------------Rgkgcel 237 Methanocaldococ...
AAG20156     130 KRVGDRTGTEVDFGRPDVLAVIDV-EAETVDVTVNSAFVYGRYRKLERGIPQTKWPCSDc-------------Ngsgtlv 195 Halobacterium s...
WP_010901702 125 KYFSARTGKEYSQDNPDLTILVNA-EYLFVDVKIRSIYIYGKYRKFRRDMPQTRWIHRP--------------N------ 183 Thermoplasma ac...
WP_010885053 141 KLFAKVTGKIPNRERPDIVIIVEP-FSSKVELQVNPIYVAGRYRKLVRGIPQTPAP-----------------G------ 196 Pyrococcus hori...
WP_010865826 164 KLLVSRGGVTVDFDSPEATLMVEF-PGGGVDIQVNSLLYKARYWKLARNISQAYWPTPE--------------G------ 222 Aeropyrum pernix
WP_010876935 124 KRVVKLLGCSAEFEDPDLVVMVDFrGDIRVWIQINPLFLEGRYRKLVRGIPQTRWPCRKcrgrgcercnytgkM------ 197 Methanothermoba...

Q60346       238 c------nytgkkYPISVEEIIAKPFLEATKGVDAKFHGAGREDIDVRMLGDGRPFVLEIKEPKIRKIDLNKIAEEINK- 310 Methanocaldococ...
AAG20156     196 dspcphcdgtgflYPESVEQLTAPPVVDAMGGTEASFHGAGREDIDALMLGTGRPFVIEVAEPQDRHPDADALADAINDf 275 Halobacterium s...
WP_010901702 184 --------------GDTVESVIGSVFTRYAGGTNYYLHGSGREDVDVRMLGNGREFVLEVENPRYREFELDPVVKEINTs 249 Thermoplasma ac...
WP_010885053 197 -------------FEESIATIICRVFKKNFRG-KCIFKGAGREDVDVRTLGRGRPFVVEIKKPRKRKVDLKLIEEEINS- 261 Pyrococcus hori...
WP_010865826 223 -------------PRYFSVEQALWPVLKLTGGERLVVHAAGREDVDARMLGSGRPMIVEVKSPRRRRIPLEELEAAANAg 289 Aeropyrum pernix
WP_010876935 198 -------------YPTSVEELIAGPILEASQGRDARFHGSGREDVDVRMLGTGRPFVLEIREPRVRNLDPESLEEEVNRr 264 Methanothermoba...

Q60346       311 -DGRVEVLNLEFGVRKDKVIFKNTPH--R--KTYRALVECSDKITDEELKLLEKELENRTIYQKTPKRVLHRRADLERIR 385 Methanocaldococ...
AAG20156     276 aDGKAEVEGVAVAGYEMVERVKELDA--R--KRYRADVEFDAPVGDDDLRDAIDELDGATIEQETPNRVDHRRAHLVRER 351 Halobacterium s...
WP_010901702 250 gKG-VEIFDVKFSSHDAVSEVKLEKH--R--KVYDALVVSDRPIDESRLLEACINLTGKNIYQRTPLRVAQRRSDLVRTR 324 Thermoplasma ac...
WP_010885053 262 -SGKVEVLELKFITPEESEKILTARH--K--KIYEALVYVKDGVSAEEVEKVVKSLKGSEIKQRTPRRVLNSRADIVRVR 336 Pyrococcus hori...
WP_010865826 290 gKGLVRFRFETAAKRAEVALYKEETArvR--KVYRALVAVEGGVSEVDVEGLRRALEGAVIMQRTPSRVLHRRPDILRRR 367 Aeropyrum pernix
WP_010876935 265 aQGMVEVEGLRFSTRKRKVELKDSSQ--SryKVYRALVELDGDVTDEDLERLG-SLD--IIKQRTPVRVSHRRADRVRER 339 Methanothermoba...

Q60346       386 KVYKVKTSKVDDN-HFEMIIYCDGGLYIKELISGDDGRTNPSVSSILNKNCICKELDVLKIHDN 448 Methanocaldococcus jannaschii D...
AAG20156     352 DVYDITADREDDT-HATVEIEGEGGLYIKELVSSDDGRTNPSLAGLLGVGAVVTALDVVAVAGE 414 Halobacterium sp. NRC-1
WP_010901702 325 RIDQVDLVGVSAN-EAEILISAEAGTYIKELVNGDGGRTRPSLSEMYGSPLNVKELDVIKICRG 387 Thermoplasma acidophilum
WP_010885053 337 RVYNVSGEYIDEH-HFKLKLVTDGGLYIKELISGDKGRTKPSVSEILGKEAWCEILDVLDVLDG 399 Pyrococcus horikoshii
WP_010865826 368 RLYSLDCSPLEGApLMECILEAEGGLYIKELVSGDGGRTRPSFAEVLGREAVCIELDVVWVEHE 431 Aeropyrum pernix
WP_010876935 340 RVLEISWNLLDG--CLELIIKGEGGLYIKELISGDSGRTEPSVSSVLGVPARCVALDVLEVGDE 401 Methanothermobacter thermautotr...
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