1O4V,3LP6,2YWX


Conserved Protein Domain Family
purE
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TIGR01162: purE 
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phosphoribosylaminoimidazole carboxylase, PurE protein
Phosphoribosylaminoimidazole carboxylase is a fusion protein in plants and fungi, but consists of two non-interacting proteins in bacteria, PurK and PurE. This model represents PurK, an N5-CAIR mutase. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Links
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Statistics
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PSSM-Id: 273474
Aligned: 32 rows
Threshold Bit Score: 168.951
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1O4V_A    16 VGIIMGSDSDLPVMKQAAEILEEFGIDYEITIVSAHRTPDRMFEYAKNAEE-RGI-EVIIAGAGGAAHLPGMVASITHLP 93  Thermotoga maritima
P51583   268 VVVLMGSTSDLGHCEKIKKACGNFGIPCELRVTSAHKGPDETLRIKAEYEG-DGIpTVFVAVAGRSNGLGPVMSGNTAYP 346 Norway rat
AAG22346 273 VVILMGSASDISHSEKIATSCRSLGLNVELRVSSAHKGPEETLRIVREYESvMSN-LIFVAVAGRSNGLGPVVSGSTNYP 351 Drosophila melanoga...
P22348     5 VMIILGSGSDIAIAEKSMKILEKLEIPYSLKIASAHRTPDLVRELVVQGTN-AGI-KVFIGIAGLAAHLPGAIAAYTHKP 82  Methanobrevibacter ...
P41654     5 VMILLGSASDFRIAEKAMEIFEELRIPYDLRVASAHRTHEKVKAIVSEAVK-AGV-EVFIGIAGLSAHLPGMISANTHRP 82  Methanothermobacter...
Q58033     2 ICIIMGSESDLKIAEKAVNILKEFGVEFEVRVASAHRTPELVEEIVKNSK----A-DVFIAIAGLAAHLPGVVASLTTKP 76  Methanocaldococcus ...
P22348   197 VVIIVGRHTDLITGKKVSVTLDRLKIPHDMQVICPIRSGKKFRAYVNTMK---NA-KIFIGINSNSSQVSGGLVGLTEKP 272 Methanobrevibacter ...
P41654   191 VSVIPGSYSDMKIAKKTTMFLERMGISYDLNVISPIRYPERFERYLEKME---NV-KLFIAISGLSAHVTGAVVALSDRP 266 Methanothermobacter...
Q10457   271 VLVIMGSGSDGVFARKISDEAKKFGLETTLKVSSAHKTTSDTLEVIADFEE-SGVpTVVIAVAGRSNGLGPVIAGNSSLP 349 Caenorhabditis elegans
2YWX_A     2 ICIIMGSESDLKIAEKAVNILKEFGVEFEVRVASAHRTPELVEEIVKNSKA-----DVFIAIAGLAAHLPGVVASLTTKP 76  Methanocaldococcus ...

1O4V_A    94 VIGVPVKTStLNGLDsLFSIVQMPGGVPVATVAINNAknAGILAASILGIKYPEIARKVKEYKERMKREVLEKAQRLE 171 Thermotoga maritima
P51583   347 VISCPPITA-DWGAQdVWSSLRLPSGIGCSTILSPEG--SAQFAAQIFGLNNHLVWAKLRASKLNTWISLKQADKKIR 421 Norway rat
AAG22346 352 VINCP-PVKsDNMQVdVWSSLNLPSGLGCATVLYPEA--AALHAATILGLGNFMVWSKLRVKALNNFITLKKADKELR 426 Drosophila melanogaster
P22348    83 VIGVPVDVK-VSGLDaLYSSVQMPYPSPVATVGIDRGdnGAILAARILGLYDEEIRKKVLESKEGYRQKVIKNNEEIV 159 Methanobrevibacter sm...
P41654    83 VIGVPVDVK-LGGLDaLFACSQMPFPAPVATVGVDRGenAAILAAQIIGIGDPGVRERVADLRRGFYERVRRDECQVL 159 Methanothermobacter t...
Q58033    77 VIAVPVDAK-LDGLDaLLSSVQMPPGIPVATVGIDRGenAAILALEILALKDENIAKKLIEYREKMKKKVYASDEKVK 153 Methanocaldococcus ja...
P22348   273 VIGVPCENE--LGNNyLLSTVNMPPGVPVATVGVNNGrnAAVLSGEILSINNPVLLELLEKL----------KNKKIN 338 Methanobrevibacter sm...
P41654   267 VIGVPCPLK-MNGWDsLLSMINMPPGVPVGTVGVGNGgnAAILAAEMLGIYDEKIESRIKRI----------KSRSVK 333 Methanothermobacter t...
Q10457   350 VINCPPPSE-STSLD-IWSSLRMPNGIGCTTVLDPSE--AALAAAKILASHNHIVFGKVLTAQLKNQINIYNANRKLE 423 Caenorhabditis elegans
2YWX_A    77 VIAVPVDAK-LDGLDaLLSSVQMPPGIPVATVGIDRGenAAILALEILALKDENIAKKLIEYREKMKKKVYASDEKVK 153 Methanocaldococcus ja...
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