4BOF_A 9 VYSEIGKLKKVLLHRPGKEIENLMPDYLERLLFDDIPFLEDAQKEHDAFAQALRDEGIEVLYLETLAAESLVTP--EIRE 86 Streptococcus p... AAF93596 6 VGSEVGQLRRVLLNRPERALTHLTPSNCHELLFDDVLAVEAAGVEHDAFANTLRTQDVEVLLLHDLLEETLAIP--EARQ 83 Vibrio cholerae... O53088 7 VNSEIGKLKTVLLKRPGKEVENITPDIMYRLLFDDIPYLPTIQKEHDQFAQTLRDNGVEVLYLENLAAEAIDAG--DVKE 84 Lactobacillus s... P23793 13 VYSEIGELESVLVHEPGREIDYITPARLDELLFSAILESHDARKEHKQFVAELKANDINVVELIDLVAETYDLAsqEAKD 92 Mycoplasma argi... WP_003111744 10 VHSEAGKLRKVMVCSPGLAHQRLTPSNCDELLFDDVIWVNQAKRDHFDFVTKMRERGIDVLEMHNLLTETIQNP--EALK 87 Pseudomonas WP_002557431 11 IFSEIGRLKKVLLHRPGEELENLTPLIMKNFLFDDIPYLKVARQEHEVFVNILKDNSVEIEYVEDLVSEVLASSv-ALKN 89 Lyme disease sp... 1LXY_A 12 VYSEIGELESVLVHEPGREIDYITPARLDELLFSAILESHDARKEHKQFVAELKANDINVVELIDLVAETYDLAsqEAKD 91 Mycoplasma argi... WP_003405169 7 sNSEVGALRVVILHRPGAELRRLTPRNTDQLLFDGLPWVSRAQDEHDEFAELLASRGAEVLLLSDLLTEALHHSg-AARM 85 Mycobacterium t... AAF93596 6 VGSEVGQLRRVLLNRPERALTHLTPSNCHELLFDDVLAVEAAGVEHDAFANTLRTQDVEVLLLHDLLEETLAIP--EARQ 83 Vibrio cholerae... O53088 7 VNSEIGKLKTVLLKRPGKEVENITPDIMYRLLFDDIPYLPTIQKEHDQFAQTLRDNGVEVLYLENLAAEAIDAG--DVKE 84 Lactobacillus s... P23793 13 VYSEIGELESVLVHEPGREIDYITPARLDELLFSAILESHDARKEHKQFVAELKANDINVVELIDLVAETYDLAsqEAKD 92 Mycoplasma argi... WP_003111744 10 VHSEAGKLRKVMVCSPGLAHQRLTPSNCDELLFDDVIWVNQAKRDHFDFVTKMRERGIDVLEMHNLLTETIQNP--EALK 87 Pseudomonas WP_002557431 11 IFSEIGRLKKVLLHRPGEELENLTPLIMKNFLFDDIPYLKVARQEHEVFVNILKDNSVEIEYVEDLVSEVLASSv-ALKN 89 Lyme disease sp... 1LXY_A 12 VYSEIGELESVLVHEPGREIDYITPARLDELLFSAILESHDARKEHKQFVAELKANDINVVELIDLVAETYDLAsqEAKD 91 Mycoplasma argi... WP_003405169 7 sNSEVGALRVVILHRPGAELRRLTPRNTDQLLFDGLPWVSRAQDEHDEFAELLASRGAEVLLLSDLLTEALHHSg-AARM 85 Mycobacterium t...
4BOF_A 87 AFIDEYLSEANi-RGRATKKAIRELLMAIEDnQELIEKTMAGVQKSelpeipasekgltDLve-snYPFAIDPMPNLYFT 164 Streptococcus p... AAF93596 84 WLLNTQISDFR--FGPTFARELRHALNHLDD-HHLTTLLLGGLAFSelhlesdsmlpkmRQp----LDFVIEPLPNHLFT 156 Vibrio cholerae... O53088 85 AFLDKMLNESHi-KSPQVQAALKDYLISMAT-LDMVEKIMAGVRTNeidik---skaliDVsadddYPFYMDPMPNLYFT 159 Lactobacillus s... P23793 93 KLIEEFLEDSEpvLSEEHKVVVRNFLKAKKTsRELVEIMMAGITKY-------------DLgieadHELIVDPMPNLYFT 159 Mycoplasma argi... WP_003111744 88 WILDRKITADS--VGLGLTSELRSWLESLEP-RKLAEYLIGGVAADdlpaseganilkmYReylghSSFLLPPLPNTQFT 164 Pseudomonas WP_002557431 90 KFISQFILEAEi-KTDGVINILKDYFSNLTV-DNMVSKMISGVAREelkdc---efsldDWvn-gsSLFVIDPMPNVLFT 163 Lyme disease sp... 1LXY_A 92 KLIEEFLEDSEpvLSEEHKVVVRNFLKAKKTsRELVEIMMAGITKY-------------DLgieadHELIVDPMPNLYFT 158 Mycoplasma argi... WP_003405169 86 QGIAAAVDAPR--LGLPLAQELSAYLRSLDP-GRLAHVLTAGMTFNelpsdtrtdvslvLRmh-hgGDFVIEPLPNLVFT 161 Mycobacterium t... AAF93596 84 WLLNTQISDFR--FGPTFARELRHALNHLDD-HHLTTLLLGGLAFSelhlesdsmlpkmRQp----LDFVIEPLPNHLFT 156 Vibrio cholerae... O53088 85 AFLDKMLNESHi-KSPQVQAALKDYLISMAT-LDMVEKIMAGVRTNeidik---skaliDVsadddYPFYMDPMPNLYFT 159 Lactobacillus s... P23793 93 KLIEEFLEDSEpvLSEEHKVVVRNFLKAKKTsRELVEIMMAGITKY-------------DLgieadHELIVDPMPNLYFT 159 Mycoplasma argi... WP_003111744 88 WILDRKITADS--VGLGLTSELRSWLESLEP-RKLAEYLIGGVAADdlpaseganilkmYReylghSSFLLPPLPNTQFT 164 Pseudomonas WP_002557431 90 KFISQFILEAEi-KTDGVINILKDYFSNLTV-DNMVSKMISGVAREelkdc---efsldDWvn-gsSLFVIDPMPNVLFT 163 Lyme disease sp... 1LXY_A 92 KLIEEFLEDSEpvLSEEHKVVVRNFLKAKKTsRELVEIMMAGITKY-------------DLgieadHELIVDPMPNLYFT 158 Mycoplasma argi... WP_003405169 86 QGIAAAVDAPR--LGLPLAQELSAYLRSLDP-GRLAHVLTAGMTFNelpsdtrtdvslvLRmh-hgGDFVIEPLPNLVFT 161 Mycobacterium t...
4BOF_A 165 RDPFATIGTGVSLNHMFSETRNRETLYGKYIFTHHPIYGGGkvPMVY-D----RNETTRIEGGDELVLSKDVLAVGISQR 239 Streptococcus p... AAF93596 157 RDTSCWVYGGVSLNPMMKPARQRETNHLRAIYRWHPIFAQHpfIHYF-GiddlHYDNANIEGGDVLVIGKGAVLIGMSER 235 Vibrio cholerae... O53088 160 RDPAASMGDGLTINKMTFEARQRESMFMEVIMQHHPRFANQgaQVWR-D----RDHIDRMEGGDELILSDKVLAIGISQR 234 Lactobacillus s... P23793 160 RDPFASVGNGVTIHYMRYKVRQRETLFSRFVFSNHPKLINT--PWYY-D----PSLKLSIEGGDVFIYNNDTLVVGVSER 232 Mycoplasma argi... WP_003111744 165 RDTTCWIYGGVTLNPMYWPARRQETLLTTAIYKFHPEFANAefEIWY-GdpdkDHGSSTLEGGDVMPIGNGVVLIGMGER 243 Pseudomonas WP_002557431 164 RDPFASIGNGITINKMYTKVRRRETIFAEYIFKYHSAYKENv-PIWF-N----RWEETSLEGGDEFVLNKDLLVIGISER 237 Lyme disease sp... 1LXY_A 159 RDPFASVGNGVTIHYMRYKVRQRETLFSRFVFSNHPKLINT--PWYY-D----PSLKLSIEGGDVFIYNNDTLVVGVSER 231 Mycoplasma argi... WP_003405169 162 RDSSIWIGPRVVIPSLALRARVREASLTDLIYAHHPRFTG----VRRaY----ESRTAPVEGGDVLLLAPGVVAVGVGER 233 Mycobacterium t... AAF93596 157 RDTSCWVYGGVSLNPMMKPARQRETNHLRAIYRWHPIFAQHpfIHYF-GiddlHYDNANIEGGDVLVIGKGAVLIGMSER 235 Vibrio cholerae... O53088 160 RDPAASMGDGLTINKMTFEARQRESMFMEVIMQHHPRFANQgaQVWR-D----RDHIDRMEGGDELILSDKVLAIGISQR 234 Lactobacillus s... P23793 160 RDPFASVGNGVTIHYMRYKVRQRETLFSRFVFSNHPKLINT--PWYY-D----PSLKLSIEGGDVFIYNNDTLVVGVSER 232 Mycoplasma argi... WP_003111744 165 RDTTCWIYGGVTLNPMYWPARRQETLLTTAIYKFHPEFANAefEIWY-GdpdkDHGSSTLEGGDVMPIGNGVVLIGMGER 243 Pseudomonas WP_002557431 164 RDPFASIGNGITINKMYTKVRRRETIFAEYIFKYHSAYKENv-PIWF-N----RWEETSLEGGDEFVLNKDLLVIGISER 237 Lyme disease sp... 1LXY_A 159 RDPFASVGNGVTIHYMRYKVRQRETLFSRFVFSNHPKLINT--PWYY-D----PSLKLSIEGGDVFIYNNDTLVVGVSER 231 Mycoplasma argi... WP_003405169 162 RDSSIWIGPRVVIPSLALRARVREASLTDLIYAHHPRFTG----VRRaY----ESRTAPVEGGDVLLLAPGVVAVGVGER 233 Mycobacterium t...
4BOF_A 240 TDAASIEKLLVNIFKQn-LGFKKVLAFEFANNRKFMHLDTVFTMVDYDKFTIHPEIEGDL---RVYSVTYD-NEELHIV- 313 Streptococcus p... AAF93596 236 TSPQGVENLAAALFKH--GQASKVIAINLPKHRSCMHLDTVMTHMDVDTFSVYPEVMRKDl-pTWRLTPKG-NNGDMRV- 310 Vibrio cholerae... O53088 235 TSAQSIEELAKVLFANh-SGFEKILAIKIPHKHAMMHLDTVFTMIDYDKFTIHPGIQGAGgmvDTYILEPG-NNDEIKI- 311 Lactobacillus s... P23793 233 TDLQTVTLLAKNIVANkeCEFKRIVAINVPKWTNLMHLDTWLTMLDKDKFLYSPIANDVFk-fWDYDLVNG-GAEPQPV- 309 Mycoplasma argi... WP_003111744 244 SSRQAIGQVAQSLFAk--GAAERVIVAGLPKSRAAMHLDTVFSFCDRDLVTVFPEVVKEIvpfSLRPDPSS-PYGMNIR- 319 Pseudomonas WP_002557431 238 TEAGSVEKLAASLFKNk-APFSTILAFKIPKNRAYMHLDTVFTQIDYSVFTSFTSDDMYf---SIYVLTYNsNSNKINIk 313 Lyme disease sp... 1LXY_A 232 TDLQTVTLLAKNIVANkeCEFKRIVAINVPKWTNLMHLDTWLTMLDKDKFLYSPIANDVFk-fWDYDLVNG-GAEPQPV- 308 Mycoplasma argi... WP_003405169 234 TTPAGAEALARSLFDD--DLAHTVLAVPIAQQRAQMHLDTVCTMVDTDTMVMYANVVDTLeafTIQRTPDG-----VTI- 305 Mycobacterium t... AAF93596 236 TSPQGVENLAAALFKH--GQASKVIAINLPKHRSCMHLDTVMTHMDVDTFSVYPEVMRKDl-pTWRLTPKG-NNGDMRV- 310 Vibrio cholerae... O53088 235 TSAQSIEELAKVLFANh-SGFEKILAIKIPHKHAMMHLDTVFTMIDYDKFTIHPGIQGAGgmvDTYILEPG-NNDEIKI- 311 Lactobacillus s... P23793 233 TDLQTVTLLAKNIVANkeCEFKRIVAINVPKWTNLMHLDTWLTMLDKDKFLYSPIANDVFk-fWDYDLVNG-GAEPQPV- 309 Mycoplasma argi... WP_003111744 244 SSRQAIGQVAQSLFAk--GAAERVIVAGLPKSRAAMHLDTVFSFCDRDLVTVFPEVVKEIvpfSLRPDPSS-PYGMNIR- 319 Pseudomonas WP_002557431 238 TEAGSVEKLAASLFKNk-APFSTILAFKIPKNRAYMHLDTVFTQIDYSVFTSFTSDDMYf---SIYVLTYNsNSNKINIk 313 Lyme disease sp... 1LXY_A 232 TDLQTVTLLAKNIVANkeCEFKRIVAINVPKWTNLMHLDTWLTMLDKDKFLYSPIANDVFk-fWDYDLVNG-GAEPQPV- 308 Mycoplasma argi... WP_003405169 234 TTPAGAEALARSLFDD--DLAHTVLAVPIAQQRAQMHLDTVCTMVDTDTMVMYANVVDTLeafTIQRTPDG-----VTI- 305 Mycobacterium t...
4BOF_A 314 EEKGDLAELLAANLGvEKVDLIRCGg--DNLVAAGREQWNDGSNTLTIAPGVVVVYNRNTITNAILESKGLKLIKIHGSE 391 Streptococcus p... AAF93596 311 EQVPSYLHAIEQALGvDYLKIITTG---GNSYEAEREQWNDANNVLTVKPGVVIGYERNVYTNEKYDKAGIKVLTIPGNE 387 Vibrio cholerae... O53088 312 THQTDLEKVLRDALEvPELTLIPCGg--GDAVVAPREQWNDGSNTLAIAPGVVVTYDRNYVSNENLRQYGIKVIEVPSSE 389 Lactobacillus s... P23793 310 ENGLPLEGLLQSIIN-KKPVLIPIAgegASQMEIERETHFDGTNYLAIRPGVVIGYSRNEKTNAALEAAGIKVLPFHGNQ 388 Mycoplasma argi... WP_003111744 320 REEKTFLEVVAESLGlKKLRVVETGg---NSFAAEREQWDDGNNVVCLEPGVVVGYDRNTYTNTLLRKAGVEVITISASE 396 Pseudomonas WP_002557431 314 KEKAKLKDVLSFYLG-RKIDIIKCAg--GDLIHGAREQWNDGANVLAIAPGEVIAYSRNHVTNKLFEENGIKVHRIPSSE 390 Lyme disease sp... 1LXY_A 309 ENGLPLEGLLQSIIN-KKPVLIPIAgegASQMEIERETHFDGTNYLAIRPGVVIGYSRNEKTNAALEAAGIKVLPFHGNQ 387 Mycoplasma argi... WP_003405169 306 GDAAPFAEAAAKAMGiDKLRVIHTG---MDPVVAEREQWDDGNNTLALAPGVVVAYERNVQTNARLQDAGIEVLTIAGSE 382 Mycobacterium t... AAF93596 311 EQVPSYLHAIEQALGvDYLKIITTG---GNSYEAEREQWNDANNVLTVKPGVVIGYERNVYTNEKYDKAGIKVLTIPGNE 387 Vibrio cholerae... O53088 312 THQTDLEKVLRDALEvPELTLIPCGg--GDAVVAPREQWNDGSNTLAIAPGVVVTYDRNYVSNENLRQYGIKVIEVPSSE 389 Lactobacillus s... P23793 310 ENGLPLEGLLQSIIN-KKPVLIPIAgegASQMEIERETHFDGTNYLAIRPGVVIGYSRNEKTNAALEAAGIKVLPFHGNQ 388 Mycoplasma argi... WP_003111744 320 REEKTFLEVVAESLGlKKLRVVETGg---NSFAAEREQWDDGNNVVCLEPGVVVGYDRNTYTNTLLRKAGVEVITISASE 396 Pseudomonas WP_002557431 314 KEKAKLKDVLSFYLG-RKIDIIKCAg--GDLIHGAREQWNDGANVLAIAPGEVIAYSRNHVTNKLFEENGIKVHRIPSSE 390 Lyme disease sp... 1LXY_A 309 ENGLPLEGLLQSIIN-KKPVLIPIAgegASQMEIERETHFDGTNYLAIRPGVVIGYSRNEKTNAALEAAGIKVLPFHGNQ 387 Mycoplasma argi... WP_003405169 306 GDAAPFAEAAAKAMGiDKLRVIHTG---MDPVVAEREQWDDGNNTLALAPGVVVAYERNVQTNARLQDAGIEVLTIAGSE 382 Mycobacterium t...
4BOF_A 392 LVRGRGGPRCMSMPFEREDI 411 Streptococcus pyogenes AAF93596 388 LGRGRGGARCMSCPIERDGI 407 Vibrio cholerae O1 biovar El Tor str. N16961 O53088 390 LSRGRGGPRCMSMPLVRRKT 409 Lactobacillus sakei P23793 389 LSLGMGNARCMSMPLSRKDV 408 Mycoplasma arginini WP_003111744 397 LGRGRGGGHCMTCPIVRDPI 416 Pseudomonas WP_002557431 391 LSRGRGGPRCMSMSLVREDI 410 Lyme disease spirochete 1LXY_A 388 LSLGMGNARCMSMPLSRKDV 407 Mycoplasma arginini WP_003405169 383 LGTGRGGPRCMSCPAARDPL 402 Mycobacterium tuberculosis complex AAF93596 388 LGRGRGGARCMSCPIERDGI 407 Vibrio cholerae O1 biovar El Tor str. N16961 O53088 390 LSRGRGGPRCMSMPLVRRKT 409 Lactobacillus sakei P23793 389 LSLGMGNARCMSMPLSRKDV 408 Mycoplasma arginini WP_003111744 397 LGRGRGGGHCMTCPIVRDPI 416 Pseudomonas WP_002557431 391 LSRGRGGPRCMSMSLVREDI 410 Lyme disease spirochete 1LXY_A 388 LSLGMGNARCMSMPLSRKDV 407 Mycoplasma arginini WP_003405169 383 LGTGRGGPRCMSCPAARDPL 402 Mycobacterium tuberculosis complex
Lu S et al.(2020). "CDD/SPARCLE: the conserved domain database in 2020.",