1IJA


Conserved Protein Domain Family
sortase_fam

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TIGR01076: sortase_fam 
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LPXTG-site transpeptidase (sortase) family protein
This family includes Staphylococcus aureus sortase, a transpeptidase that attaches surface proteins by the Thr of an LPXTG motif to the cell wall. It also includes a protein required for correct assembly of an LPXTG-containing fimbrial protein, a set of homologous proteins from Streptococcus pneumoniae, in which LPXTG proteins are common. However, related proteins are found in Bacillus subtilis and Methanobacterium thermoautotrophicum, in which LPXTG-mediated cell wall attachment is not known. [Cell envelope, Other, Protein fate, Protein and peptide secretion and trafficking]
Statistics
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PSSM-Id: 130148
View PSSM: TIGR01076
Aligned: 7 rows
Threshold Bit Score: 172.673
Threshold Setting Gi: 1724013
Created: 8-Oct-2014
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1IJA_A        16 GYIEIPDADIKEPVYPGPA--TPEQLNRGVSFAEENESLDDQNISIAGHTFIdRPNYQFTNLKAAKKGSMVYFKVGNETR 93  Staphylococcus ...
AAC13546      89 ARLKIPSISLDLPVYHGTAddTLLKGLGHLEGTSLPVGGEGTRSVITGHRGL-AEATMFTNLDKVKTGDSLIVEVFGEVL 167 Actinomyces nae...
P54603        73 GILEIPKINAELPIVEGTDadDLEKGVGHYKDSYYP--DENGQIVLSGHR-----DTVFRRTGELEKGDQLRLLLSYGEF 145 Bacillus subtil...
EHD83230      52 GYVEIPAIDQEIPMYVGTSedILQKGAGLLEGASLPVGGENTHTVITAHRGL-PTAELFSQLDKMKKGDIFYLHVLDQVL 130 Streptococcus p...
EHE11244     104 GHVEIPVIDVDLPVYAGTAeeVLQQGAGHLEGTSLPIGGNSTHAVITAHTGL-PTAKMFTDLTKLKVGDKFYVHNIKEVM 182 Streptococcus p...
WP_000091735  96 GYLSIPSLEIMEPVYLGADyhHLGMGLAHVDGTPLPLDGTGIRSVIAGHRAE-PSHVFFRHLDQLKVGDALYYDNGQEIV 174 Streptococcus p...
AAD48437      74 GYIEIPDADIKEPVYPGPA--TPEQLNRGVSFAEENESLDDQNISIAGHTFIdRPNYQFTNLKAAKKGSMVYFKVGNETR 151 Staphylococcus ...
1IJA_A        94 KYKMTSIRDVKPTDVGVLDEQKG-KDkQLTLITCDDYNEKt------GVWEKRKIFVATEVK 148 Staphylococcus aureus
AAC13546     168 TYRVTSTKVVEPEETEALRVEEG-KD-LLTLVTCTPLGINth---riLLTGERIYPTPAKDL 224 Actinomyces naeslundii
P54603       146 TYEIVKTKIVDKDDTSIITLQHE-KE-ELILTTCYPFSYVgnapkryIIYGKRVT------- 198 Bacillus subtilis subsp. subtilis...
EHD83230     131 AYQVDQIVTVEPNDFEPVLIQHG-ED-YATLLTCTPYMINsh---rlLVRGKRIPYTAPIAE 187 Streptococcus pneumoniae GA07643
EHE11244     183 AYQVDQVKVIEPTNFDDLLIVPG-HD-YVTLLTCTPYMINth---rlLVRGHRIPYVAEVEE 239 Streptococcus pneumoniae GA17328
WP_000091735 175 EYQMMDTEIILPSEWEKLESVSS-KN-IMTLITCDPIPTFnk---rlLVNFERVAVYQKSDP 231 Streptococcus pneumoniae
AAD48437     152 KYKMTSIRDVKPTDVGVLDEQKGkDK-QLTLITCDDYNEKt------GVWEKRKIFVATEVK 206 Staphylococcus aureus
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