1KON,1LFP,1MW7


Conserved Protein Domain Family
TIGR01033

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TIGR01033: TIGR01033 
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DNA-binding regulatory protein, YebC/PmpR family
This model describes a minimally characterized protein family, restricted to bacteria excepting for some eukaryotic sequences that have possible transit peptides. YebC from E. coli is crystallized, and PA0964 from Pseudomonas aeruginosa has been shown to be a sequence-specific DNA-binding regulatory protein. In silico analysis suggests a role in Holliday junction resolution. [Regulatory functions, DNA interactions]
Statistics
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PSSM-Id: 273405
Aligned: 17 rows
Threshold Bit Score: 294.6
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1KON_A         4 MAGHsKWANTRHRKAAQDAKRGKIFTKIIRELVTAAKLGGGDP-DANPRLRAAVDKALSNNMTRDTLNRAIARGVGg--D 80  Escherichia coli
O84463         1 MAGHsKWANTKHRKERADHKKGKIFSRTIKELISAVKMGGPDP-KSNARLRMIIQKAKDQNIPNENIERNLKKASS---A 76  Chlamydia trach...
Q9Z7Y0         1 MAGHsKWANTKHRKERADHKKGKIFSRIIKELISAVKLGGADP-KSNARLRMVIQKAKENNIPNENIERNLKKATS---A 76  Chlamydia pneum...
O83487         1 MSGHsKWATIKHAKGAADAKRGQLFTKFIKEISVAARMAGGDP-QANPRLRTAILKARAANMPKDNIERAIKKGTGe--L 77  Treponema palli...
P94447         1 MAGHsKWKNIQKRKNAQDAKRGKIFMKLAKEIYVAAKEGGADP-EANSALRLVIEKAKGANMPNENIDRAIKKAAGg--Q 77  Bacillus subtil...
O33214         1 MSGHsKWATTKHKKAVVDARRGKMFARLIKNIEVAARVGGGDP-AGNPTLYDAIQKAKKSSVPNENIERARKRGAGe-eA 78  Mycobacterium t...
Q9ZD88         1 MAGHsKFKNIQHRKGAQDKKKSKVFTKLIREIVTAVKTGASNVpENNPRLRKALNAARSQNLPKERIDKAINSANDa--S 78  Rickettsia prow...
Q9ZMR9         1 -MGR-AFEYRRAAKEKRWDKMSKVFPKLAKAITLAAKEGGSEP-DTNAKLRTAILNAKAQNMPKDNIDAAIKRASS---- 73  Helicobacter py...
WP_010865126   2 MSGHnKWANIKHRKMAQDAKKSKIFTKLIREIIVAAREGGGNI-ETNPRLRAAVERARAENMPKENIERAIKRGTGe--L 78  Thermotoga mari...
P74514         1 MGGR-KWQSIKRQKARVDAQKGKTTTQLSRAIIVAARQGIPDP-AGNFQLRTAIEKARAAGVPNDSIDRAIAKGAGtyeD 78  Synechocystis s...
1KON_A        81 DDANMETIIYEGYGPGGTAIMIECLSDNRNRTVAEVRHAFSK-CGGNLGTDGSVAYLFSKKGVISFEK------GDE-DT 152 Escherichia coli
O84463        77 DQKNYEEVTYELYGFGGVGIIVEAMTDNKNRTASDMRVAVNK-RGGALVEPGSVLYNFSRKGACYVPKh----sIDE-AS 150 Chlamydia trach...
Q9Z7Y0        77 EQKNFEEVTYELYGHGGVGIIVEAMTDNKNRTASDMRIAINK-RGGSLVEPGSVLYNFARKGACTVAKs----sIDE-EV 150 Chlamydia pneum...
O83487        78 SGSSYEELVYEGYAPGGVAVLVEVLTDNKNRAAANVRNLFSR-NGGNLGSAGSVSYMFNRKGVIEYDSe----qVDE-EA 151 Treponema palli...
P94447        78 DGSSYEEITYEGYGPSGIAVMVECVTDNKNRTASNVRTAFNK-NGGSLGESGCVAFLFERKGFITIDRte--rqIEE-DE 153 Bacillus subtil...
O33214        79 GGADWQTIMYEGYAPNGVAVLIECLTDNRNRAASEVRVAMTR-NGGTMADPGSVSYLFSRKGVVTLEKn----gLTE-DD 152 Mycobacterium t...
Q9ZD88        79 NNESYMEIRYEGYAPNGIAIIVEALTDNKNRTASEVRSSFTK-YGGILGETGSVNYLFNHCGVIQYPIn-----IASnED 152 Rickettsia prow...
Q9ZMR9        74 KEGNLSEITYEGKANFGVLIIMECMTDNPTRTIANLKSYFNKtQGASIVPNGSLEFMFNRKSVFECLKsevenlKLSlED 153 Helicobacter py...
WP_010865126  79 EGVDYQEVIYEGYAPGGVAVYIRALTDNKNRTAQELRHLFNK-YGGSLAESGSVSWIFERKGVIEISRd----kVKDlEE 153 Thermotoga mari...
P74514        79 GESNYEEMRYEGYGPGGVAVLIEALTDNRNRTAADLRAAFSK-KGGNLGETGCVSWMFSQKGVIRLVGe-----LEE-EK 151 Synechocystis s...
1KON_A       153 IMEAALEAGAEDVVTYDDGa---IDVYTAWEEMGKVRDALEAAGLKADSAEVSMIPSTKADMDA-ETAPKLMRLIDMLED 228 Escherichia coli
O84463       151 LLTHMIDCGGEDLDSDDEEf---FLVLCEPTDLASVKEALLAKGVTCSEERLIYVPLRLVDCDE-ETGKSNLALIEWLEN 226 Chlamydia trach...
Q9Z7Y0       151 IFSYAIEAGAEDLDTEDEEn---FLVICAPSELASVKEKLISQGATCSEDRLIYLPLRLVDCDE-KDGEANLALIDWLEQ 226 Chlamydia pneum...
O83487       152 LMELALEAGAEDIQNAGGV----LTVTTVPGTFETVLESLQAKGWESLSAGISMVPDTYLALDE-ETARKVLKMIDRLEE 226 Treponema palli...
P94447       154 LMLDVLEAGGEELRIEEDL----YEVFTEPEHFEEVKTALESK-YLISSAEVTMLPNTYAEADD-QAVEKLETLIDVLED 227 Bacillus subtil...
O33214       153 VLAAVLEAGAEDVNDLGDS----FEVISEPAELVAVRSALQDAGIDYESAEASFQPSVSVPVDl-DGARKVFKLVDALED 227 Mycobacterium t...
Q9ZD88       153 IFEAAIQAGGNDIISDYIT----HTIYTDIENFYKALGFLTDKYGIPEDSYIGWIPVNTIIIDDkEKAKKLLKLIAVLEE 228 Rickettsia prow...
Q9ZMR9       154 LEFALIDYGLEELEEVGDK----IIIRGDYNSFKLLNEGFESLRLPIIKAGLQRIATTPIELND-EQMELTEKLLDRIED 228 Helicobacter py...
WP_010865126 154 LMMIAIDAGAEDIKDAEDP----IQIITAPENLSEVKSKLEEAGYEVE-AKVTFIPKNTVKVTG-KDAEKVLEFLNALED 227 Thermotoga mari...
P74514       152 LLEALLEGEGESYEWLDEEdgggVEVFSAVNQLENLNQVLQNHGFTIAETELRWLPENTIEIAEpDQAKALMQMIDTLES 231 Synechocystis s...
1KON_A       229 CDDVQEVYHNGE 240 Escherichia coli
O84463       227 INDVDDVYHNMA 238 Chlamydia trachomatis D/UW-3/CX
Q9Z7Y0       227 IEDVDDVYHNMS 238 Chlamydia pneumoniae
O83487       227 EEDVQAVYSNAD 238 Treponema pallidum subsp. pallidum str. Nichols
P94447       228 DDDVQEVYTNYR 239 Bacillus subtilis subsp. subtilis str. 168
O33214       228 SDDVQNVWTNVD 239 Mycobacterium tuberculosis
Q9ZD88       229 NDDVQRVFGNYM 240 Rickettsia prowazekii str. Madrid E
Q9ZMR9       229 DDDVVALYTNIE 240 Helicobacter pylori J99
WP_010865126 228 MDDVQEVYSNFE 239 Thermotoga maritima
P74514       232 LDDVQSVTSNFE 243 Synechocystis sp. PCC 6803 substr. Kazusa
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