3J01,2WWB,1RHZ


Conserved Protein Domain Family
3a0501s007
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TIGR00967: 3a0501s007 
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preprotein translocase, SecY subunit
Members of this protein family are the SecY component of the SecYEG translocon, or protein translocation pore, which is driven by the ATPase SecA. This model does not discriminate bacterial from archaeal forms. [Protein fate, Protein and peptide secretion and trafficking]
Links
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Statistics
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PSSM-Id: 273369
Aligned: 22 rows
Threshold Bit Score: 296.892
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3J01_A    13 KRRLLFVIGALIVFRIGSFIPIPGIDAAVLAklleqQRgtiIEMFNMFSGGALSraSIFALGIMPYISASIIIQLLTv-v 91  Escherichia coli 536
Q05207    15 RNKIIFTLLMLIVFRLGSFIPVPHVNTEVLKaq-dqMSv--FGILNTFGGGALFnfSILAMGIMPYITASIIIQLLQmdv 91  Bacillus lichenifor...
P16336    15 RNKIIFTLLMLIVFRIGAFIPVPYVNAEALQaq-sqMGv--FDLLNTFGGGALYqfSIFAMGITPYITASIIIQLLQmdv 91  Bacillus subtilis s...
Q05217    15 RNKIFFTLAMLVIFKIGTYIPAPGVNPAAFDnnqgsQGv--TDLLNTFGGGALKnfSIFAMGIMPYITASIVMQLLQmdi 92  Staphylococcus carn...
P27148    16 RARILFTIFILFVFRLGAHITAPGVNVQNLQqv-adLPf--LSMMNLVSGNAMQnySLFAMGVSPYITASIIVQLLQmdi 92  Lactococcus lactis ...
P10250    38 IYRILFTLLALIIIRLGVYITVPGVTLDKRFatdssRIq-fFQLLSTLGGGSIGrfSILALGVSPYITASIIVQLLStdv 116 Mycoplasma capricol...
Q60175    24 KEKLKWTGIVLVLYFIMGCIDVYTAGAQIP------AI---FEFWQTITASRIG--TLITLGIGPIVTAGIIMQLLVg-- 90  Methanocaldococcus ...
P28542    27 KRKLTWTGGVLLLYFFLTNVKLFGLDIDASQ-----QV---FGRFSSILASGQG--SIMQLGIGPIVTASIVLQLLGg-- 94  Haloarcula marismor...
BAA85159  29 KEKVLWTAITLFIFLVCCQIPLFGIMSSDSA-----DP---FYWMRVILASNRG--TLMELGISPIVTSGLIMQLLAg-- 96  house mouse
2WWB_A    29 KEKVLWTAITLFIFLVCCQIPLFGIMSSd------sADp--FYWMRVILASNRG--TLMELGISPIVTSGLIMQLLAgak 98  dog

3J01_A    92 HPTLAEIKKeGESGRRKISQYTRYGTLVLAIFQSIGIAtglpnmPGmq----------gLVINPGFAFYFTAVVSLVTGT 161 Escherichia coli 536
Q05207    92 VPKFTEWSKqGEVGRRKLAQFTRYFTIVLGFIQALG-Ms-----YGfnnm-----aggaLITDPGVGTYLLIAIVLTAGT 160 Bacillus lichenifor...
P16336    92 VPKFTEWSKqGEVGRRKLAQFTRYFTIVLGFIQALG-Ms-----YGfnnl-----angmLIEKSGVSTYLIIALVLTGGT 160 Bacillus subtilis s...
Q05217    93 VPKFTEWAKqGDVGRKKLNNVTRYFAIILAFIQSIG-Ma-----FQfnny-----lkgaLIIDPSPMSYLLIAIVLTTGT 161 Staphylococcus carn...
P27148    93 LPKFVEWSKqGEIGRRKLNQATRYITLVLAMAQSIG-It-----AGfqam-----sslnIVQNPNWQSYLMIGVLLTTGS 161 Lactococcus lactis ...
P10250   117 IPVLTRWSKsGERGRKKLDKLTKIIMIPFALMQAEATIf-----TLssqgliipgwdntNAIANSAFYYILIPLVMLGGS 191 Mycoplasma capricol...
Q60175    91 SGIIQMDLS-IPENRALFQGCQKLLSIIMCFVEAVLFVg-----AG-------------AFGILTPLLAFLVIIQIAFGS 151 Methanocaldococcus ...
P28542    95 ADLLGLNTQdDPRDQILYQGLQKLLVLVMICLTGLPMVf-----AGgflpad--tavanSLGIGTAGVQWLIFAQMFVGG 167 Haloarcula marismor...
BAA85159  97 AKIIEVG-D-TPKDRALFNGAQKLFGMIITIGQSIVYVm-----TGmy----------gDPSEMGAGICLLITIQLFVAG 159 house mouse
2WWB_A    99 I----IEVGdTPKDRALFNGAQKLFGMIITIGQSIVYVm-----TGmy----------gDPSEMGAGICLLITIQLFVAG 159 dog

3J01_A   162 MFLMWLGEQITE-RGIGNGISIIIFAGIVAGLPPAIAHTIE-----------------------QARQGDLHflvll-lv 216 Escherichia coli 536
Q05207   161 AFLMWLGEQITS-HGVGNGISIIIFAGIVAGIPQTINQIYA-----------------------QQFVDAGDqlflq-ii 215 Bacillus lichenifor...
P16336   161 AFLMWLGEQITS-HGVGNGISIIIFAGIVSSIPKTIGQIYE-----------------------TQFVGSNDqlfih-iv 215 Bacillus subtilis s...
Q05217   162 AFLLWLGEQITQ-YGVGNGISIIIFAGILSTLPSSLIQFYQ-----------------------QAFVGQSDttmaw--l 215 Staphylococcus carn...
P27148   162 MVVTWMGEQINE-KGFGSGVSVIIFAGIVSGIPSAIKSVYD-----------------------EKFLNVRPseipmswi 217 Lactococcus lactis ...
P10250   192 FFMLWIADQITI-KGIGNGISIVIFIGIIISMPSNLKSTFEy---------------------wVSNSGEEAniffsgll 249 Mycoplasma capricol...
Q60175   152 IILIYLDEIVSK-YGIGSGIGLFIAAGVSQTIFVGALGPegylw-----------------kflnsLIQGVPnieyi--- 210 Methanocaldococcus ...
P28542   168 VLILFMDEVISK-WGVGSGIGLFIVAGVSQRLVGGLLTAPFlgnsegiiytwylfitgergtgpVLAADGLQtvllqgel 246 Haloarcula marismor...
BAA85159 160 LIVLLLDELLQKgYGLGSGISLFIATNICETIVWKAFSPTTvntgrgmefegaiialfhllatrTDKVRALReafyrqnl 239 house mouse
2WWB_A   160 LIVLLLDELLQKgYGLGSGISLFIATNICETIVWKAFSPTTvntgrgmefegaiialfhllatrTDKVRALReafyrqnl 239 dog

3J01_A   217 avlVFAVTFFVVFV-----ERgqRRIVVNYAkrqQgrrvyaaQSTHLPLKVNMAGVIPAIFASSIILFPATIASWfGGGT 291 Escherichia coli 536
Q05207   216 kvvVILVAILAIVVgvifiQQavRKISIQYAkgsGrspvpggQSTHLPLKVNPAGVIPVIFAVAFITTPRTVATFfGSND 295 Bacillus lichenifor...
P16336   216 kvaLLVIAILAVIVgvifiQQavRKIAIQYAkgtGrspagggQSTHLPLKVNPAGVIPVIFAVAFLITPRTIASFfGTND 295 Bacillus subtilis s...
Q05217   216 qvaGLVIGLVLLTMgavyvLQavRKIPIQYAkkqStqr-lgsNATYLPLKVNSAGVIPVIFAMAFFLLPRTLTMFfPKAD 294 Staphylococcus carn...
P27148   218 fviGLILSAIVIIYvttfvQQaeRKVPIQYTkltQga----ptSSYLPLRVNPAGVIPVIFAGSITTAPATILQFlQRSQ 293 Lactococcus lactis ...
P10250   250 nfmIYISVFLLVILsvvimNEaeRKIPIQQTgsgLtds--seHTPYLPLKLNNAGVIPVIFASAIISTPITISQIiEAVN 327 Mycoplasma capricol...
Q60175   211 ---apiigTIIVFLmvvyaECmrVEIPLAHGrikG-------AVGKYPIKFVYVSNIPVILAAALFANIQLWG-LaLYRM 279 Methanocaldococcus ...
P28542   247 lglF---TTVLIFAvvvyaESvrVEIPLSNArvkG-------ARGRFPVKLIYASVLPMILVRALQANIQFLGRIlNAQL 316 Haloarcula marismor...
BAA85159 240 pnlMNLIATIFVFAvviyfQGfrVDLPIKSAryrG-------QYNTYPIKLFYTSNIPIILQSALVSNLYVISQMlSARF 312 house mouse
2WWB_A   240 pnlMNLIATIFVFAvviyfQGfrVDLPIKSAryrG-------QYNTYPIKLFYTSNIPIILQSALVSNLYVISQMlSARF 312 dog

3J01_A   292 --------------------------Gw---------------------------NWLTTISLYLQ--------PGQPLY 310 Escherichia coli 536
Q05207   296 v-----------------------------------------------------tNWIQKT---FD--------YTHPVG 311 Bacillus lichenifor...
P16336   296 v-----------------------------------------------------tKWIQNN---FD--------NTHPVG 311 Bacillus subtilis s...
Q05217   295 w-----------------------------------------------------aQQIANT---AN--------PSSNIG 310 Staphylococcus carn...
P27148   294 --------------------------Gsnv----------------------gwlSTLQNA---LS--------YTTWTG 314 Lactococcus lactis ...
P10250   328 --------------------------Pds------------------------gfVIFTRD--YLS--------FNTWWG 347 Mycoplasma capricol...
Q60175   280 --------------------------Gipilghye------------ggravdgiAYYLSTPYGLSs------vISDPIH 315 Methanocaldococcus ...
P28542   317 --------------------------Gsmpaflgty----------angqptgglFYFLAPIQSRGdwmwwlegTAQPVW 360 Haloarcula marismor...
BAA85159 313 --------------------------SgnllvsllgtwsdtssggparaypvgglCYYLSPPESFGs------vLEDPVH 360 house mouse
2WWB_A   313 sgnllvsllgtwsdtssggparaypvGg--------------------------lCHYLSPPESFGs------vLEDPVH 360 dog

3J01_A   311 VLLY---------ASA----IIFFCFFYTA-L-VFNPRETADNLKKSGAFVPGIRPGEq-TAKYIDKVMTRLTLVGALYI 374 Escherichia coli 536
Q05207   312 MGVY---------AAL----IIAFTYFYAF-V-QVNPEQMADNLKKQGGYIPGVRPGKm-TQDRITSILYRLTFVGSIFL 375 Bacillus lichenifor...
P16336   312 MAIY---------VAL----IIAFTYFYAF-V-QVNPEQMADNLKKQGGYIPGVRPGKm-TQDRITSILYRLTFVGSIFL 375 Bacillus subtilis s...
Q05217   311 MVIY---------IIL----IIAFTYFYAF-V-QVNPEKMSDNLKKQGSYVPGIRPGEq-TKKYITKVLYRLTFVGSIFL 374 Staphylococcus carn...
P27148   315 MLFY---------ALL----IVLFTFFYSF-V-QVNPEKMAENLQKQGSYIPSVRPGKg-TEKYVSRLLMRLATVGSLFL 378 Lactococcus lactis ...
P10250   348 ISIF---------GIL----IVLFTFLYSQ-V-QINPEKIAENFQKSGTFIPGIKPGKd-TTKYLTGIINRLSVVGSVFL 411 Mycoplasma capricol...
Q60175   316 AIVYmi-----amIIT----CVMFGIFWVEtT-GLDPKSMAKRIGSLGMAIKGFRKSEkaIEHRLKRYIPPLTVMSSAFV 385 Methanocaldococcus ...
P28542   361 QILTrvgidlfvmLVG----GAVFAVFWVEtT-DMGPEATAKQIHNSGMQIPGFRQNVgvIEKVLERYIPQVTVIGGALV 435 Haloarcula marismor...
BAA85159 361 AVVYiv-----fmLGS----CAFFSKTWIEvS-GSSAKDVAKQLKEQQMVMRGHRETS--MVHELNRYIPTAAAFGGLCI 428 house mouse
2WWB_A   361 AVVY---------IVFmlgsCAFFSKTWIE-VsGSSAKDVAKQLKEQQMVMRGHRETSm--VHELNRYIPTAAAFGGLCI 428 dog

3J01_A   375 TFICLIPEFMRDAMKvpf--yfgGTSLLIVVVVIMDFMAQVQTLMMSSq-Y 422 Escherichia coli 536
Q05207   376 AVIAILPVLFVNIAGlpssaqigGTSLLIVIGVALETMKQLESQLVKRn-Y 425 Bacillus licheniformis DSM 13 = ATCC 14580
P16336   376 AVISILPIFFIQFAGlpqsaqigGTSLLIVVGVALETMKQLESQLVKRn-Y 425 Bacillus subtilis subsp. subtilis str. 168
Q05217   375 AVIAILPILATKFMNlpqsiqvgGTSLLIVIGVAIETMKSLEAQVNQKe-Y 424 Staphylococcus carnosus subsp. carnosus TM300
P27148   379 GLISIIPIAAQNVWGlpkivalgGTSLLILIQVAIQAVKQLEGYLLKRk-Y 428 Lactococcus lactis subsp. cremoris
P10250   412 AIIALLPYVISKLTQlpsnlaigGTGLIICISVAIQTVQQLKGRIIQQn-F 461 Mycoplasma capricolum subsp. capricolum ATCC 27343
Q60175   386 GFLATIANFIGALGG--------GTGVLLTVSIVYRMYEQLLREK--VseL 426 Methanocaldococcus jannaschii DSM 2661
P28542   436 GLLAVMANMLGTIGGv------sGTGLLLTVSITYKLYEEIAEEQ--LmeM 478 Haloarcula marismortui ATCC 43049
BAA85159 429 GALSVLADFLGAIGS--------GTGILLAVTIIYQYFEIFVKEq----sE 467 house mouse
2WWB_A   429 GALSVLADFLGAIGS--------GTGILLAVTIIYQYFEIFVKEQsevgsm 471 dog
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