Conserved Protein Domain Family
2A73

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TIGR00947: 2A73 
putative bicarbonate transporter, IctB family
This family of proteins is suggested to transport inorganic carbon (HCO3-), based on the phenotype of a mutant of IctB in Synechococcus sp. strain PCC 7942. Bicarbonate uptake is used by many photosynthetic organisms including cyanobacteria. These organisms are able to concentrate CO2/HCO3- against a greater than ten-fold concentration gradient. Cyanobacteria may have several such carriers operating with different efficiencies. Note that homology to various O-antigen ligases, with possible implications for mutant cell envelope structure, might allow alternatives to the interpretation of IctB as a bicarbonate transport protein. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Statistics
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PSSM-Id: 273357
Aligned: 10 rows
Threshold Bit Score: 470.709
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_010999199  28 LVGLLSSWRQTSFLLQWGDMIAAALLSLIYVLAPFVSSTLVGVLLIACVGFWLLLTLSDEPSSNnnslVTPIHLLVLLYW 107 Nostoc sp. PCC ...
BAM51784      19 LVGWGQSWIQASVLWPHFEALGTALVAIIFIAAPFTSTTMLGIFMLLCGAFWALLTFADQPGKG----LTPIHVLVFAYW 94  Bacillus subtil...
WP_011613088  30 LNGSLYNWRRGSWLMQWGEPLGFVLLAIVFTLAPFVNTTLIGFLLLASAGFWVLLKVSDNTQEY----LTPIHLLIFLYW 105 Trichodesmium e...
WP_011243468  26 LFGSLRAWRASSQLLVWSEALGGFLLAVVYGSAPFVPSSALGLGLAAIAAYWALLSLTDIDLRQ----ATPIHWLVLLYW 101 Synechococcus e...
WP_011058082  22 LLGLLQGWQEKSWLGRWLPSLAVLLVGLVLVLAPLMPSGMIGMLLAAGSGFWLLWTLAGEREGR----WSGVHLLVLLYW 97  Thermosynechoco...
WP_011143733  39 VQQWLLHWAASGMAARVAEPVAMGVFCLLLLISPFVPTAAVGAVLAVGLALVVLLFCVRARP------LSPLALPVSAFW 112 Gloeobacter vio...
WP_011430353  30 VSGSLRSWGKSSLLVQTSDWIGLGLVLLYWVFSAQSSTGILGLILLAMAALVVLGWLVETPT------WLPVHLPLGLFW 103 Synechococcus s...
WP_011618303  22 LLSWQGVLPASEQQRRRLSWLASILLMVLLAGLPFLTRTGLGLVVLACGALWILWSSVSQPQR-----IGAISAWVLLFL 96  Synechococcus s...
WP_011127158  13 LLRWQGCLTPTASVQQRLELLSGVVLMLLLGSLPFVSRSGLGLELAAAGLLWLLWSLIT-PAKR----LGAISRWVLLYL 87  Synechococcus s...
WP_011363307  16 LVRWQGLIAPDQAVLKRLESLAGLLLLVLLTGLPLFSRTGLALVVTACGALWLLWCLCSPPHER----IGTISRWLMLFL 91  Synechococcus s...
WP_010999199 108 GIAAVATALSPVKKAALTDLLTLTLYLLLFALCARVL-RSPRLRSWIITLYLSASLVVSIYGMRQWRFGAPPLATWVDPE 186 Nostoc sp. PCC ...
BAM51784      95 CISAIAVGFSPVKMAAASGLAKLTANLCLFLLAARLL-QNKQWLNRLVTVVLLVGLLVGSYGLRQQVDGVEQLATWNDPT 173 Bacillus subtil...
WP_011613088 106 SIATLAVVISPAKTAAFSGWVKLTLYLLLFASGSLVL-RSPRLRSWLINIYLLVSLVVSFYGIRQWIDKVEPLATWNDPT 184 Trichodesmium e...
WP_011243468 102 GVDALATGLSPVRAAALVGLAKLTLYLLVFALAARVL-RNPRLRSLLFSVVVITSLFVSVYGLNQWIYGVEELATWVDRN 180 Synechococcus e...
WP_011058082  98 GIALLATVLSPVPRAAMVGLGKLTLYLLFFALAERVM-RNERWRSRLLTVYLLTALMVSVEGVRQWIFGAEPLATWTDPE 176 Thermosynechoco...
WP_011143733 113 LSGWVALIGSPRLLSSLDGWLKMTLYAAGFALGAHLL-QKPLYRTLAVGTYLAATLPVSIYGLLQYVNGAPPLATWVDPE 191 Gloeobacter vio...
WP_011430353 104 GIATLATILSPVPYAAREGWLKLTLYLAGYLLLQRLL-RQLQFRDWIVGSLLLVSLAMGVYGLRQYFYGAAELATWVDPE 182 Synechococcus s...
WP_011618303  97 GIALLATGFSPVPAAATKGLIKLLSYLGVYALMRQLLaERPDWWDRLVAALLGGELLTSVMALRQLYGPTEELARWADPN 176 Synechococcus s...
WP_011127158  88 AIAWVCTGFSPVPIAAAKGLLKLTSYLGVYALMRTLLeRQIVWWDRLLAALLGGGLFSSVLALRQLYASTDELAGWADPN 167 Synechococcus s...
WP_011363307  92 AIAIVATGCSPVPIAASKGLIKLLSYLGVYALLCKLLlSNSRWWDRLVAGLLSGGLLSSVLALRQLYASSEELARWADPN 171 Synechococcus s...
WP_010999199 187 STLSKTTRVYSYLGNPNLLAGYLVPAVIFSLMAVFVWQGWARKSLAVTMLFVNTACLIFTYSRGGWIGLVVAVLGATALL 266 Nostoc sp. PCC ...
BAM51784     174 STLAQATRVYSFLGNPNLLAAYLVPMTGLSLSALVVWRRWWPKLLGATMVIVNLLCLFFTQSRGGWLAVLALGATFLALC 253 Bacillus subtil...
WP_011613088 185 SAQAGATRVYSYLGNPNLLGGYLLPAIALSFVAIFAWSSWARKSLAVTILLVSCACLRYTGSRGSWIGFLALMFAMLILM 264 Trichodesmium e...
WP_011243468 181 SVADFTSRVYSYLGNPNLLAAYLVPTTAFSAAAIGVWRGWLPKLLAIAATGASSLCLILTYSRGGWLGFVAMIFVWALLG 260 Synechococcus e...
WP_011058082 177 SALANVTRVYSFLGNPNLLAGYLLPSVPLSAAAIAVWQGWLPKLLAVVMLGMNAASLILTFSRGGWLGLVAATIAGVVLL 256 Thermosynechoco...
WP_011143733 192 SPLADTTRVYSFLGNPNLLAAYLIAAIPLGVVGALVWKNWAAKAMAALAAGAGALCLVLTYSRGGWIALTATVLVLAVLL 271 Gloeobacter vio...
WP_011430353 183 SGLAGLTRVYSYLRNPNLYGGYLIPVIPLGLAATWIWPSWGAKLLAGFTTAVNLICLLLTYSRGAWIGGLATLTLMAVLL 262 Synechococcus s...
WP_011618303 177 SVAAGTIRIYGPLGNPNLLAGYLVPILPLALVALIRWNGWGARCYAAVALGLGATATLFSYSRGGWLGMLAALGVLLLLL 256 Synechococcus s...
WP_011127158 168 SVSAGTIRIYGPLGNPNLLAGYLLPLVPLACIAVLRWKRLSCRLLAAVTALLAGSATVFTYSRGGWLGLLAALALAGMLI 247 Synechococcus s...
WP_011363307 172 SISAGTIRIYGPLGNPNLLAGYLLPLIPFAAIALVRWRGVGAQLFAGTTLVLAPTATLFTYSRGGWLGMVAAGAVLLLLL 251 Synechococcus s...
WP_010999199 267 VDWWSVQMPPFWRTWSLPILLGGLIGVLLIAVLFVEPVRFRVLSIFADRQDSSNNFRRNVWDAVFEMIRDRPIIGIGPGH 346 Nostoc sp. PCC ...
BAM51784     254 YFWWLPQLPKFWQRWSLPLAIAVAVILGGGALIAVEPIRLRAMSIFAGREDSSNNFRINVWEGVKAMIRARPIIGIGPGN 333 Bacillus subtil...
WP_011613088 265 WYWWRSYMPSFWQIWSLPIAVGSFAGLLILAVVLLEPLRDRVLSVFAGRQDSSNNFRMNVWMSVFDMIRDRPILGIGPGN 344 Trichodesmium e...
WP_011243468 261 LYWFQPRLPAPWRRWLFPVVLGGLVAVLLVAVLGLEPLRVRVLSIFVGREDSSNNFRINVWLAVLQMIQDRPWLGIGPGN 340 Synechococcus e...
WP_011058082 257 GIWFWPRLPLQWRRWGVPTMGGLAIALCMGTIVSVPPLRERAASIFVARGDSSNNFRINVWMAVQQMIWARPWLGIGPGN 336 Thermosynechoco...
WP_011143733 272 WPWLAERLKPEWRLWVPVVILGTVAAALVVAVVAVPAVGERALSIFDGRDDSSNNFRITVWGAVFEMIRAYPLTGIGPGN 351 Gloeobacter vio...
WP_011430353 263 AQWHSVDLPARWRRWALPALLGGGGAALLLGILTVRSLRLRVQSLFWGRLDTSNNFRINVWAAVLDMIRDFPILGIGPGN 342 Synechococcus s...
WP_011618303 257 VLRAIRNWPKLWRRLVPIALLVLAGVALAIAVTQVDPIRTRVASLLAGRGDSSNNFRINVWLAAVEMIQDRPWLGIGPGN 336 Synechococcus s...
WP_011127158 248 LLRTTAHWPPLWRRLLPLAALLIAGIALALAITQLDPIRTRVLSLVAGRGDSSNNFRINVWLAAIEMVQDRPWLGIGPGN 327 Synechococcus s...
WP_011363307 252 LLRWTRHWPPLWRRLVPLAMLLVGAACLVVAATQIDPIRTRITSLLAGRGDSSNNFRINVWMAAIQMVQDRPWLGIGPGN 331 Synechococcus s...
WP_010999199 347 NSFNKVYPLYQ-RPRYSALSAYSIFLEVAVEMGFVGLACFLWLIIVTINTAFVQLRQLRQSANVQGFWLVGALATLLGML 425 Nostoc sp. PCC ...
BAM51784     334 EAFNQIYPYYM-RPRFTALSAYSIYLEILVETGVVGFTCMLWLLAVTLGKGVELVKRCRQTLAPEGIWIMGALAAIIGLL 412 Bacillus subtil...
WP_011613088 345 DVFNKIYPLYQ-RPRYSALSSYSVPLEIVVETGFIGLTAFLWLLLVTFNQGVLQLKRLRDADNPQGYWLIGAIAAMVGLI 423 Trichodesmium e...
WP_011243468 341 TAFNLVYPLYQ-QARFTALSAYSVPLEVAVEGGLLGLTAFAWLLLVTAVTAVRQVSRLRRDRNPQAFWLMASLAGLAGML 419 Synechococcus e...
WP_011058082 337 VAFNQIYPLYQvNVRFTALGAYSIFLEILVEVGFIGFGVFLWLLAVLGDRARRCFEELRATGSPQGFWLMGTIAAMIGML 416 Thermosynechoco...
WP_011143733 352 LTFEAIYPFFQ-RPKFDALSAYSIVLELTVELGIVGLLAFLWLASAMLVQGFTVW--VRRAEPVGALWCAAATCAVVGLL 428 Gloeobacter vio...
WP_011430353 343 VAFNRVYPLYQ-RGNFSALGAYSVPLQLTVETGFIGSLTFAWFLLVLWDHGWRCWKTLLNLRDPQGLWVAAGLAACTGMM 421 Synechococcus s...
WP_011618303 337 AAFNAVYPLYQ-QPKFNALSAYSVPLELLVETGIPGLIAALGLAGASLRNGLRALRSTAALALP---WL-GCLAAIAGLV 411 Synechococcus s...
WP_011127158 328 AAFNSIYPLYQ-QPKFDALSAYSVPLEILVETGIPGLLACLGLLLSSIQRGLR-------IHGQQGLIAIGSLAAIAGLL 399 Synechococcus s...
WP_011363307 332 AAFNSIYPLYQ-QPKFNALSAYSVPLEILVETGIPGLLACLGLLATSLRQGLLQL----NANGSSALTSIASLAAIAGLL 406 Synechococcus s...
WP_010999199 426 AHGTVDTIWFRPEVNTLWWLMVALIASYWTP 456 Nostoc sp. PCC 7120
BAM51784     413 VHGMVDTVWYRPPVSTLWWLLVAIVASQWAS 443 Bacillus subtilis BEST7613
WP_011613088 424 GHGLVDTVWYRPQVNTIWWLMVAIIASYSSQ 454 Trichodesmium erythraeum
WP_011243468 420 GHGLFDTVLYRPEASTLWWLCIGAIASFWQP 450 Synechococcus elongatus
WP_011058082 417 THGLVDTIWFRPEVATLWWLMVAIVASFTPF 447 Thermosynechococcus elongatus
WP_011143733 429 VNGLTDTVWFRPSVQVVWWMLCALIGAEYLR 459 Gloeobacter violaceus
WP_011430353 422 VHGLVDTIWYRPQVQMLWWLAVALITASLAS 452 Synechococcus sp. JA-3-3Ab
WP_011618303 412 IQGATDTIFFRPEVQIIGWFCLATLSQAQQA 442 Synechococcus sp. CC9311
WP_011127158 400 TQGITDTIFFRPEVQLIGWFALASLGATWLR 430 Synechococcus sp. WH 8102
WP_011363307 407 MQGSTDTIFFRPEVQLIGWFALASLVSQPMK 437 Synechococcus sp. CC9605
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