Conserved Protein Domain Family
2a37

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TIGR00932: 2a37 
transporter, monovalent cation:proton antiporter-2 (CPA2) family
[Transport and binding proteins, Cations and iron carrying compounds]
Statistics
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PSSM-Id: 273348
Aligned: 12 rows
Threshold Bit Score: 182.079
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
AAD01191      21 LLASVIFVPLFQKIPGGs------PVLGYLAAGILIGPYGLSIIRNVH----------GTRAIAEFGVVLLLFNIGLELS 84  thale cress
P45522        14 LFAAVAAVPLASRLGIG-------AVLGYLLAGIAIGPWGLGFISDVD----------EILHFSELGVVFLMFIIGLELN 76  Escherichia col...
AAA84962      11 LAAVVLADPLSRRLGLG-------SVLGYLAGGAVIGPWGLKLISDVE----------HIFHVAELGVVVLLLFVSLELQ 73  Myxococcus xanthus
P03819        13 LGSAALIVPIAVRLGLG-------SVLGYLIAGCIIGPWGLRLVTDAE----------SILHFAEIGVVLMLFIIGLELD 75  Escherichia col...
P44933        16 LASSVTIVPLFKRLGLG-------SVLGYLVAGCLIGPSVFGIVQEPT----------AVVHLAELGVVMFLFIIGLEMY 78  Haemophilus inf...
AAC60780      15 LVLAFLLGSLAHRLRSS-------PLVGYLAAGVLAGPFTPGFVADTS----------LAPELAEIGVILLMFGVGLHFS 77  Yersinia entero...
BAA06982      15 ALAAVLCGGMMTRLKQP-------AVVGYILAGVVLGPSGFGLVSNRD----------AVATLAEFGVLMLLFVIGMKLD 77  Magnetospirillu...
AAB40041      11 LFATKIAGHLSVRLGQP-------SVLGKLLIGIILGPAVLGWIHNDQ----------FVHYFSEIGVLLLMFLAGLETD 73  Bacillus megate...
P26235        11 LVATTIGSHISRRFGIP-------AVIGQLLVGVLLGQAGLGWVHPNI----------LVHDFSEIGVILLMFLAGLESD 73  Enterococcus hirae
P40309        27 LFQACLILLVCNLIHIPfsmmrqpKVISEVISGVILGPTIFGQIPNYTntifptssipGLNLVANLGIILFMFFLGLEVD 106 Saccharomyces c...
WP_010880229  17 FLSAFLAPLFSRILRMP-------VPVGELIFGILIGNFFVG-IQVPE----------ILNFLSDFGFLLLMFLAGLELD 78  Aquifex aeolicus
WP_010877728  14 SLTAFISPLIADKLRVP-------VVVLEIVLGMIFGVSFLNVIYASE----------WLSFLSLFGLIFLMFLAGLEID 76  Archaeoglobus f...
AAD01191      85 VERLSSMKKYVFGLGSAQVLVTA---AVVGLlAHYVAGQAGP---------AAIVIGNGLALSSTAVVLQVLQERGESTS 152 thale cress
P45522        77 PSKLWQLRRSIFGVGAAQVLLSA---ALLAG-LLMLTDFAWQ---------AAVVGGIGLAMSSTAMALQLMREKGMNRS 143 Escherichia col...
AAA84962      74 TSRLWALRRSVFGLGGAQVLFTG---ALLAS-VGLLCSLTWG---------AAIVTGFGLSLSSTAFALQLLVERNRLTT 140 Myxococcus xanthus
P03819        76 PQRLWKLRAAVFGCGALQMVICG---GLLGL-FCMLLGLRWQ---------VAELIGMTLALSSTAIAMQAMNERNLMVT 142 Escherichia col...
P44933        79 PERLWAMRKAIFGRGLLQVGLCG---CLLTFsGIYLLGLTKE---------VSFIAGMGFTLSSTAIVMQSLEERGLTST 146 Haemophilus inf...
AAC60780      78 LKDLLAVKAIAIPGAVAQIAVA----TLLGMgLSHLLGWDLM---------TGFVFGLCLSTASTVVLLRALEERQLIDS 144 Yersinia entero...
BAA06982      78 IIRFLEVWKTAIFTTVLQIAGS----VGTALlLRHGLGWSLG---------LAVVLGCAVAVSSTAVVIKVLESSDELDT 144 Magnetospirillu...
AAB40041      74 LEQLKRNWKAAFAVAVLGIILP----FIGGFgVGELFGLGAT---------YSLFIGVLLCATSVSITVQVLKDMNRLNS 140 Bacillus megate...
P26235        74 LSLLKKYFKPGMFVALLGILFP----VFFGWlTGEAFQVANN---------EAIFFGIILAATSVSISVEVLKELNVVNT 140 Enterococcus hirae
P40309       107 IAFIKKHLKKALVIGIVTLAVPFgfgCLLAIpLFHTYANKTEgerhikfsvFMVFIAVSISVTAFPVLCRILNELRLIKD 186 Saccharomyces c...
WP_010880229  79 FN-----LIEKADKKQNAVYISY---VLLIFlSAFVFGILLG---------IGTAPAIILSLISLGLMVATLKDMSVLEE 141 Aquifex aeolicus
WP_010877728  77 AD-------VVLKSGHLKRVVAF---FALSLaLSVALTALMG---------LNLFYAIILTNVAVGVVVSVLREIGLEKE 137 Archaeoglobus f...
AAD01191     153 RHGRASFSVLLFQDLAVVVLLILIPLISpnsskggiGFQAIAEALGLAAVKAAvAITAIIAGGRLLLRPIYKQIAENRNA 232 thale cress
P45522       144 ESGQLGFSVLLFQDLAVIPALALVPLLA--------GSADEHFDWMKVGMKVL-AFVGMLIGGRYLLRPVFRFIAASGVR 214 Escherichia col...
AAA84962     141 PYGQLAFGILLFQDLAVVPLLALLPLLGd------gGAPSPGTVWLLLLKDVG-VLLAEVLSGRYLVRPAFRAVAATHRQ 213 Myxococcus xanthus
P03819       143 QMGRSAFAVLLFQDIAAIPLVAMIPLLAt------sSASTTMGAFALSALKVAgALVLVVLLGRYVTRPALRFVARSGLR 216 Escherichia col...
P44933       147 SKGQRVISTLIFEDIAIVPLLASVAFLAph-----sKEATPHTDWVSIGIALS-AVVGLIVTGKWLMNPLFRLISKARIR 220 Haemophilus inf...
AAC60780     145 QRGQIAIGRSIVEDLAMVLTLVLLPAFAgvmgnettSLSQLFTELAITIGKVIaFITLMIVVGRRLVPWILAKTASTGSR 224 Yersinia entero...
BAA06982     145 PVGRTTLGILIAQDMAVVPMMLVLESFEt------------KALLPADMARVVlSVLFLVLLFWWLSKRRIDLPITARLS 212 Magnetospirillu...
AAB40041     141 REGSTILGAAVVDDVLVVVLLAIMISFLg---------TGEEVSLGLLVGKKLiFFIGAVLAGWLVVPKVLDWLTNLKVT 211 Bacillus megate...
P26235       141 KEGSTILGASVVDDILVVLVLSFSLSFLt-------gKSTSNLPLPLLLLEQLfYFLFIFLLVKWIAPFLMSLAEKIYAN 213 Enterococcus hirae
P40309       187 RAGIVVLAAGIINDIMGWILLALSIILSs--------AEGSPVNTVYILLITFaWFLIYFFPLKYLLRWVLIRTHELDRS 258 Saccharomyces c...
WP_010880229 142 PFAKKVLLIGVFGEIISLLALTLMEKLLhfh--gfvSLIKELGVIFVFFFSFFlGFYLTRLLVWWYPEIVNRLTYEEDPS 219 Aquifex aeolicus
WP_010877728 138 DFGQLNIVTALVSDFSTMFLLSIYFITG-----------YLQVAFAFLIILVFlAAYRFGKLVIWHFPDFISRWFSDEPS 206 Archaeoglobus f...
AAD01191     233 ---EIFSANTLLVILGTSL-LTARAGLSMALGAFLAGLLLAETEF-S-LQ-VESDIAPYR-GLLLGLFFMTVGMSID 301 thale cress
P45522       215 ---EVFTAATLLLVLGSAL-FMDALGLSMALGTFIAGVLLAESEY-R-HE-LETAIDPFK-GLLLGLFFISVGMSLN 283 Escherichia coli K-12
AAA84962     214 ---ELFTATALLLVVATAS-VINAVGLSMGLAASLAGVLLADSEY-R-HE-LEADLAPFK-GLLMGLFFISVGMTVN 282 Myxococcus xanthus
P03819       217 ---EVFSAVALFLVFGFGL-LLEEVGLSMAMGAFLAGVLLASSEY-R-HA-LESDIEPFK-GLLLGLFFIGVGMSID 285 Escherichia coli K-12
P44933       221 ---EMMTAGALLVVLGAAL-AMEIGGLSMAMGAFVAGVMMSESAF-R-HQ-LEADIEPFR-GLLLGLFFMGVGMSLD 289 Haemophilus influe...
AAC60780     225 ---ELFTLAVLVLALGIAYgAVGLFDVSFALGAFFAGMVLNESEL-S-HR-AAQDTLPLR-DAFAVLFFVSVGMLFD 294 Yersinia enterocol...
BAA06982     213 rdsDLATLSTLAWCFGTAA-ISGVLDLSPAYGAFLGGVVLGNSAQ-R-DM-LLKRAQPIG-SVLLMVFFLSIGLLLD 284 Magnetospirillum m...
AAB40041     212 ---EPVVSIGLAICFGYVY-FADLMGMAGIIGAFAAGIAISQTSY-R-HT-IESKVEPIAyAVFVPVFFVSIGLNVS 281 Bacillus megaterium
P26235       214 ---SAIIIMSLVICLGMSY-LADLIGLSSVIGAFFAGIAVSQTKV-K-HE-VYNNVEALGyAVFIPVFFVSVGLEVD 283 Enterococcus hirae
P40309       259 kpsPLATMCILFIMFISAY-FTDIIGVHPIFGAFIAGLVVPRDDH-YvVK-LTERMEDIPnIVFIPIYFAVAGLNVD 332 Saccharomyces cere...
WP_010880229 220 ---ALGIRLSLFLMFTSSI-FAKLAGIESVLGAFMAGVVFSYFIR-E-KKdLEEKLSSIGyGFLIPIFFIKTGMGME 290 Aquifex aeolicus
WP_010877728 207 ---EIGVRGSLAIMILFVG-LSSLLGVEAILGAFLAGVLLSITFRgG-KK-LYDKLYGMgfgffipiffiktgseln 277 Archaeoglobus fulg...
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