The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family
Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Jiyao W et al.(2023). "The conserved domain database in 2023.",