1KNC


Conserved Protein Domain Family
ahpD_dom

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TIGR00778: ahpD_dom 
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alkylhydroperoxidase AhpD family core domain
This model represents a 51-residue core region of homology among a family of mostly uncharacterized proteins of 110 to 227 amino acids. Most members of this family contain the motif EXXXXXX[SA]XXXXXC[VIL]XCXXXH. Members of the family include the alkylhydroperoxidase AhpD of Mycobacterium tuberculosis, a macrophage infectivity potentiator peptide of Legionella pneumophila, and an uncharacterized peptide in the tetrachloroethene reductive dehalogenase operon of Dehalospirillum multivorans. We suggest that many peptides containing this domain may have alkylhydroperoxidase or related antioxidant activity. [Unknown function, General]
Statistics
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PSSM-Id: 273266
Aligned: 21 rows
Threshold Bit Score: 43.1282
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1KNC_A       110 PgIPKANFELWSFAVSAINGCSHCLVAHEHTLRTVGVDREAIFEALKAAA 159 Mycobacterium tuberculosis
AAB31024      57 GaLNPKLREQIALVSAGYNGCNYCASAHTYLGEKAGINKDELKENLSGKS 106 Legionella pneumophila
CAA18907      63 GpGDRTGKEVAAFGVSQANKCRFCVDAHTMLLHATG--DHALAERLAGGL 110 Streptomyces coelicolor A3(2)
Q57498        41 NvLDAKTRELIALAVAVTTRCESCISAHAEEAVKAGASEAEVAAALATAI 90  Haemophilus influenzae Rd KW20
P27749        41 GsLPAAVKELIAVALAVQKGCDDCVLFHTSQALRHRATREQLAEVLAINI 90  Ralstonia eutropha H16
P08304        38 GaLDKRTKQLIAVAVAHVTQCPWCIEGHVKGARREGATNEQIMEAIWVAA 87  Paracoccus denitrificans
AAA88559      37 GaVPRRYRELISVAVALVTQCAYCLDVHTEAARRHGVTAEELAETAFVTA 86  Streptomyces lavendulae
BAA95687      84 SnLSKAEKEMIVVATSAANDCLYCVVAHGAILRVRSKNPR-LSEQIATNY 132 Hydrogenophilus thermoluteolus
WP_010879895  49 GkLNPILKEKIALAVSKVNYCNPCLISHSRKLEMMGESIEPLNEREKAAL 98  Archaeoglobus fulgidus
WP_027480348  66 GgLSNAERELLAVVVSGLNRCVYCAVSHGAALREFSGDAV-KADAVAVNW 114 Deinococcus radiodurans
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