3VN5


Conserved Protein Domain Family
rnhC
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TIGR00716: rnhC 
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ribonuclease HIII
This enzyme cleaves RNA from DNA-RNA hybrids. Two types of ribonuclease H in Bacillus subtilis, RNase HII (rnhB) and RNase HIII (rnhC), are both known experimentally and are quite similar to each other. The only RNase H homolog in the Mycoplasmas resembles rnhC. Archaeal forms resemble HII more closely than HIII. This model describes bacterial RNase III. [DNA metabolism, DNA replication, recombination, and repair]
Links
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Statistics
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PSSM-Id: 129799
Aligned: 4 rows
Threshold Bit Score: 376.971
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3VN5_A   3 SLKISPSEAEKIQNYLvSSGFRKINAPYTLWALEGNGVKVYYYKTGSLLIQGKNSEKVLK-----EVLNLLEKKKLP--- 74  Aquifex aeolicus VF5
P94541   5 VIKVSLSAIDQMKMTY-SGSLTASVPQGAVFQAKPPGCTITAYQSGKVLFQGKNAAAESArwgtaEPQEKKKTAKKPadp 83  Bacillus subtilis sub...
O67644   3 SLKISPSEAEKIQNYLvSSGFRKINAPYTLWALEGNGVKVYYYKTGSLLIQGKNSEKVLK-----EVLNLLEKKKLP--- 74  Aquifex aeolicus VF5
O84011   6 VSQLSPSLFSILREQLeKKGFTISIPPHTVFQGRSPTVSCTVYQSGKIVVQGKGTQEFVEfflepEILQTFSSQNVQqdl 85  Chlamydia trachomatis...

3VN5_A  75 --------------GCDESGKGDIFGSLVLCCVCIPE-ENYLKVSSLNPRDTKRLSDKRVERLYLALKPLVKAYCYEIKP 139 Aquifex aeolicus VF5
P94541  84 ryappadiagmsviGSDEVGTGDYFGPMTVVCAYVDK-TMLPLMKELGVKDSKDLKDPQIIEIARNLIKTIPYSLLVLKN 162 Bacillus subtilis sub...
O67644  75 --------------GCDESGKGDIFGSLVLCCVCIPE-ENYLKVSSLNPRDTKRLSDKRVERLYLALKPLVKAYCYEIKP 139 Aquifex aeolicus VF5
O84011  86 r----------sriGVDESGKGDFFGPLCTAGVYASSpQAIEALYKTSICDSKLIPDAKILSLAQNIRSLCACKVITLFP 155 Chlamydia trachomatis...

3VN5_A 140 EEYNKLYRKFRNLNKMMTHFYKLLIERV-KEECGVS--EVVVDKYQPSNPF----------GEDVIFETEAER-NLAVAV 205 Aquifex aeolicus VF5
P94541 163 EKYNSMQEKGMSQGKMKALLHNQAITHLlRKLDGVKpeAILIDQFAEPGVYfnhlkgrdivKERTYFSTKAEGiHLAVAA 242 Bacillus subtilis sub...
O67644 140 EEYNKLYRKFRNLNKMMTHFYKLLIERV-KEECGVS--EVVVDKYQPSNPF----------GEDVIFETEAER-NLAVAV 205 Aquifex aeolicus VF5
O84011 156 EKYNALYANFQNLNSLLAWTHATIIDNLaPHPAGAV--FAISDQFASSERVllqavrkkcsDIELIQRHRAEQ-DVVVAA 232 Chlamydia trachomatis...

3VN5_A 206 ASIFARYKFLQSLKEVERELGIKIPKGTSKEVKELAKSL---KNP---ERFIKLNFNV 257 Aquifex aeolicus VF5
P94541 243 ASIIARYSFLMEMDKLSRAAGMTLPKGAGPHVDEAAAKLilkKGAsalRTFTKLHFAN 300 Bacillus subtilis subsp. subtilis str. 168
O67644 206 ASIFARYKFLQSLKEVERELGIKIPKGTSKEVKELAKSL---KNP---ERFIKLNFNV 257 Aquifex aeolicus VF5
O84011 233 ASILAREAFLSSIHALESQYQIRLLKGASGKVKQRAKEIlhnKGQvvlEKVCKTHFKT 290 Chlamydia trachomatis D/UW-3/CX
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