Conserved Protein Domain Family
narJ

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TIGR00684: narJ 
nitrate reductase molybdenum cofactor assembly chaperone
This protein is termed NarJ in most species that have a single copy, and has been called the delta subunit of nitrate reductase. However, although it is required for correct assembly of active enzyme, it dissociates and is not part of the enzyme. Two hits to this model are found each in E. coli and in Mycobacterium tuberculosis, but in each case duplication to create paralogs appears to be recent. The NarX protein of Mycobacterium tuberculosis includes one of these paralogs as a domain, fused to structural domains of nitrate reductases before and after the NarJ-homologous region. [Protein fate, Protein folding and stabilization]
Statistics
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PSSM-Id: 273218
Aligned: 4 rows
Threshold Bit Score: 207.767
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
P42178        14 SCLLSYPDEE-WRAELPDWKALIQEIGNr-QIREKLLHFFETSASYSPEALIEHYVYTFDFGKKTNMYV-TYFNSGEQRE 90  Bacillus subtil...
P11351         8 SRLLEYPDAAlWQHQQEMFEAIAASKNLpkEDAHALGIFLRDLTTMDPLDAQAQYSELFDRGRATSLLL-FEHVHGESRD 86  Escherichia coli
WP_010866287   9 SIIFSYPSED-LEELVRNREVVKPLLIG--EDGEAAALIMEFLEKLDLERADEEYVAVFEMPPKCSIYAhTYLLKGKEDM 85  Aeropyrum pernix
WP_003406093   6 SLLLAYPDDG-LAERLHMVDALRAHQTG--PAAALLGRTVAELRALAPMAAAAQYVETFDMRRRSTMYL-TYWTAGDTRN 81  Mycobacterium t...
P42178        91 RGIELLHLKNTYEQ-SGFLPTEKELPDYLPLMLEFAAAAe---IEAARSVFEKYLSN-VRELASRLEKNDSIYAELLHVL 165 Bacillus subtil...
P11351        87 RGQAMVDLLAQYEQ-HGLQLNSRELPDHLPLYLEYLAQL----PQSEAVEGLKDIAPiLALLSARLQQRESRYAVLFDLL 161 Escherichia coli
WP_010866287  86 VGQLLLEVKSHYKAkQLDMPVDREIPTYLPAMLEYLALVydedPKAARRFAKKYLQPwVGELASCLEKNRSLWSLPAKAL 165 Aeropyrum pernix
WP_003406093  82 RGREMLAFATAYRD-AGVKPPRTEAPDYLPVVLEFAATVd---PEAGRRLLTEHRVP-IDVLRGALADAKSPYEYTVAAI 156 Mycobacterium t...
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