Q49896 1 MLTEIRIESLGAISVATAEFDRGLTVLTGETGTGKTMVVTGLHLLGGARADASRVRSGANRAVVEGRFTTTDLDdvvvAQ 80 Mycobacterium leprae TN P44496 1 MLTQLTINNFAIVRQLDIELAKGMSVITGETGAGKSIAIDALGLCFGQRVETSMVREGQERAEICATFQLESQN----PA 76 Haemophilus influenza... O33197 1 MLTELRIESLGAISVATAEFDRGFTVLTGETGTGKTMVVTGLHLLGGARADATRVRSGADRAVVEGRFTTTDLDdatvAG 80 Mycobacterium tubercu... P17894 1 MLAELSIKNFAIIEELTVSFERGLTVLTGETGAGKSIIIDAISLLVGGRGSSEFVRYGEAKAELEGLFLLESGHp--vLG 78 Bacillus subtilis sub... P74374 1 MLLSLRINNFALIDCLEINFGQGLNVLTGETGAGKSILLDAIDLLLGGKAGARVLRQGCSSGVIEGIFSTSTELn----D 76 Synechocystis sp. PCC... O83456 1 MIEQLSVRNVALIQSLALEFGAQFTALSGETGAGKSMILGALSFLCGQKVGPDLIRKDENEAWVSAVFRCDHAPr---AV 77 Treponema pallidum su... O66834 1 MLGRLYIQNFFFIRDVEVEFERGLNVITGETGTGKSMTISAIEFLMGKQG-----------------------------D 51 Aquifex aeolicus VF5
Q49896 81 LDGILNASGSERDEDGSVIVLRSVSRDGPSRSYLGGRSVPAKSLGSFTTELLALHGQNDQLRLVRPEEQRAALDRYAAAG 160 Mycobacterium leprae TN P44496 77 YHWLSEQELQDPDNPTECILRRIINADGRSKAFINSTPVSASQLKEIAQYLVHINGQHASQLLLKNDYQLQLVDNFAAHP 156 Haemophilus influenza... O33197 81 LQAVLDSSGAERDEDGSVIALRSISRDGPSRAYLGGRGVPAKSLSGFTNELLTLHGQNDQLRLMRPDEQRGALDRFAAAG 160 Mycobacterium tubercu... P17894 79 VCAEQGIDVSDE---MIVMRR-DISTSGKSVCRVNGKLVTIASLREIGRLLLDIHGQHDNQLLMEDENHLQLLDKFAGAE 154 Bacillus subtilis sub... P74374 77 WLATQAIEPLEDNTIACTREFSKKGSSLNSRSRLNGVLVNRQILAELRSQLVEITAQGQTQQLLDPGQQRQLLDLFGGQN 156 Synechocystis sp. PCC... O83456 78 HTWLAERSIEPEH--HRVLLRRVMRRTGRGTAWIQNVPVSRADLEFFTSFFIDLHGQHEHQSLFRVAEHRRFLDTYGGLQ 155 Treponema pallidum su... O66834 52 YPEGTAVELELLG--EEEIILRREVKKGRSRYYVNGKGASKSTVLELLEGKISLQGQNEFINLFREDFQRKLLDTFANLN 129 Aquifex aeolicus VF5
Q49896 161 --PSCERYRELRDAWLLARSDLIDRRNRIRELVQEADRLKFALSEIDSVDPQPG-EDNALVADIVRLSELDMLREVAVNA 237 Mycobacterium leprae TN P44496 157 --ELLVKMREDYQTWKNLQNQVKTFQQKVAENEARKQLLQYQVDELDEFNLRPN-EYLELEDEQRRLSSSEQLTQLSQSA 233 Haemophilus influenza... O33197 161 --EAVQRYRKLRDAWLTARRDLVDRRNRARELAQEADRLKFALNEIDTVDPQPG-EDVALVADIARLSELDTLREAATTA 237 Mycobacterium tubercu... P17894 155 veSALKTYQEGYQRYVKLLKKLKQLSESEQEMAHRLDLIQFQLEEIESAKLELN-EDEQLQEERQQISNFEKIYESLQNA 233 Bacillus subtilis sub... P74374 157 llEKRQAVEITYKEFTQAKQALTARQQSEQNRLQRLDFLTYQLQELTEAELTDGdEWELLIQEQEKLSHVVELQQLSYQA 236 Synechocystis sp. PCC... O83456 156 --QEVDAFTACYAALAERRAQLQRLASCEHNRQERLEFLSFALEELEHAALDVH-EERALEGEEQKLCQHEKLCDVMQRV 232 Treponema pallidum su... O66834 130 --DKVKELEKVYNSLRKKEQELFEFLRKKEELIQKKDYLEFRVREVEEIGISSE-EYEELKNKANLINNLEKVKKAVGES 206 Aquifex aeolicus VF5
Q49896 238 RAALSGaldDMDVSGSNAVACMGQAKAALESt--DDATLRAFADQVGEVLTVVVEVGRELGEYLEELPVDASALESKLVR 315 Mycobacterium leprae TN P44496 234 LQILSE---NDTVNIDSLLYRATQYIDELAE---LDPQYAEVQNMLNDALIQVQEATSEVQNLSSNIEQDPQLLQEIEQR 307 Haemophilus influenza... O33197 238 RATLCGt-pDADAFDRGAVDSLGRARAALQSs--DDAALRGLAEQVGEALTVVVDAVAELGAYLDELPADASALDAKLAR 314 Mycobacterium tubercu... P17894 234 YNALRS------EQGGLDWVGMASAQLEDISd--INEPLKKMSESVSNSYYLLEDATFQMRNMLDELEFDPERLNYIETR 305 Bacillus subtilis sub... P74374 237 TQLLYQs--ERDTPAIADLLGDAEGQLQTMAe--FDSSLNPLLELVQTALTQVIEAGRQVQRYGDNLEADPERLGEVEAR 312 Synechocystis sp. PCC... O83456 233 DAAIRG----VDLQEGALLSSLKKALGALESacgIDGSLEPARARLESAYYEIEDVAHVLRTYTDGIQFCPDRLQHVQER 308 Treponema pallidum su... O66834 207 LYKLLE-------GENSVYEILGEIRKNLAKvesYSGKFSELIEKIANLEEEVYELYNSLKEEMPEIS--EEEVNEINEK 277 Aquifex aeolicus VF5
Q49896 316 QAELCTLTRKYAADIDGVLQWARESRERLEQLDVSYERLAGVESRVDELERQLSQAAVDLSKLRRDAANRLAKEVTAELS 395 Mycobacterium leprae TN P44496 308 ISQTLQLARKHQVKPEDLVEQHKKLKAELTALLDFSESEEMLIEQEKRAFEQMQATATALTASRQQSATRLAQNVTQSIK 387 Haemophilus influenza... O33197 315 QAQLRTLTRKYAADIDGVLRWADEARARLAQLDVSEEGLAALERRTGELAHELGQAAVDLSTIRRKAAKRLAKEVSAELS 394 Mycobacterium tubercu... P17894 306 LNEIKQLKRKYGATVEDILEYASKIEEEIDQIENRDSHLQSLKKELDSVGKDVAVEAANVSQIRKTWAKKLADEIHRELK 385 Bacillus subtilis sub... P74374 313 LQVLKRICRKYGPSLTEAIAYQEKIQAEYDQLTDGEQSLAQLQESLTKAEQELIKHCGQLTLIRQKTAQKLEKRLVQELK 392 Synechocystis sp. PCC... O83456 309 LALIYRLKKKYGGTVAQVLEYRARAQQEMQDLSQAVGDKEALEQDVQRLMAQVLHAGRALSLKRHAVAEAFRTRVEGVLH 388 Treponema pallidum su... O66834 278 LFRIQRLEEKYKKSFPEILKEVEEIKEELSNLNSVDFKEEELREEVEKLREEYDKLAEEVSRDRRKKAEDLEERIEEILK 357 Aquifex aeolicus VF5
Q49896 396 ALAMVDAEFTISVTTDLIpltdykrsaavtlpsggvaRAGADGVDQVEFGFAAHRGMTVLPLAKSASGGELSRVMLALEV 475 Mycobacterium leprae TN P44496 388 QLAMENAEFYVELNTDLD-------------------KVSANGADNVIFTLRSNLGQQPQPLAKIASGGELSRISLAIQV 448 Haemophilus influenza... O33197 395 ALAMADAEFTIGVTTELAdhgdpval---alasgelaRAGADGVDAVEFGFVAHRGMTVLPLAKSASGGELSRVMLSLEV 471 Mycobacterium tubercu... P17894 386 SLYMEKSTFDTEFKVRTAsrneeap-----lvngqpvQLTEQGIDLVKFLISTNTGEPLKSLSKVASGGELSRVMLAIKS 460 Bacillus subtilis sub... P74374 393 PLAMEKVIFVCQLESSAP---------------------SSFGAEQVVFYFSPNTGEKIQPLAATASGGEMSRFLLALKA 451 Synechocystis sp. PCC... O83456 389 RLGMASTRFHVQICTRDEqca--------------kqRTGPYGFDDVEFLISANAGEPARPLAKIASGGELSRVMLALKT 454 Treponema pallidum su... O66834 358 ELNLERAKLKVEIKESEP---------------------TKYGKDKIEFLFSS-YGKDFKPLEEVASGGELSRLFLALSL 415 Aquifex aeolicus VF5
Q49896 476 VLATS---AAGTTMVFDEVDVGVGGRAAVQIGRRLARLARTHQVIVVTHLPQVAAYADVHLVVHSAGL------------ 540 Mycobacterium leprae TN P44496 449 LTSDQ---SAIPTLIFDEVDVGISGKTASVVGKLLRQLSERCQVLCVTHLPQVACHGHHQFNVEKFTV------------ 513 Haemophilus influenza... O33197 472 VLATSrkqAAGTTMVFDEIDAGVGGWAAVQIGRRLARLARTHQVIVVTHLPQVAAYADVHLMVQRTGR------------ 539 Mycobacterium tubercu... P17894 461 IFSSQ---QDVTSIIFDEVDTGVSGRVAQAIAEKIHKVSIGSQVLCITHLPQVAAMADTHLYIAKELK------------ 525 Bacillus subtilis sub... P74374 452 CFSELa--pPSQTLIFDEIDVGVSGKVAQAIADKLAQLSQRQQLLCVTHQPLVAALADAHFHVDKVVIneniadptnpql 529 Synechocystis sp. PCC... O83456 455 VLSSVd---EVGTLIFDEIDVGIGGETARAVAEHLQALSEHKQVVCITHLAMIAAHADAHVCVKKESS------------ 519 Treponema pallidum su... O66834 416 ILPAS------ETYVFDEVDAGISGETSFKVAKFLKELSKKMQVIVITHSAPLCAAGDKNFKTEKKFL------------ 477 Aquifex aeolicus VF5
Q49896 541 --DG--ASDVRRLAGD-DRVAELARMLAGLGESDSGRAHARELLDA 581 Mycobacterium leprae TN P44496 514 --DNktETKMTALSQA-ERVPALARLLGGSEITELALANAQEMLDL 556 Haemophilus influenzae Rd KW20 O33197 540 --DG--ASGVRRLTSE-DRVAELARMLAGLGDSDSGRAHARELLET 580 Mycobacterium tuberculosis P17894 526 --DGrtTTRVKPLSKQ-EKVAEIGRMIAGVEVTDLTKRHAKELLKQ 568 Bacillus subtilis subsp. subtilis str. 168 P74374 530 deDLrtVIRITPLQSDgDRQQELAQLTGG-HSAKEALAFAQSLLEK 574 Synechocystis sp. PCC 6803 substr. Kazusa O83456 520 --GEhtNTSAAHVVGE-RRVQEVARMLAGDTHSATSLAHAQELLRA 562 Treponema pallidum subsp. pallidum str. Nichols O66834 478 --GDipYIVVRELSEE-EKVEEVARLMGM--KSEKTLEGAKELVEA 518 Aquifex aeolicus VF5
Jiyao W et al.(2023). "The conserved domain database in 2023.",