Conserved Protein Domain Family
uvde
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TIGR00629: uvde 
UV damage endonuclease UvdE
All proteins in this family for which functions are known are UV dimer endonucleases that function in an alternative nucleotide excision repair process. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Links
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Statistics
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PSSM-Id: 273183
Aligned: 3 rows
Threshold Bit Score: 514.104
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q10988    246 WRGRLGYACLNTILRSMKERVFCSRTCRITTI--QRd--------------------------gLESVKQLGTQNVLDLI 297 Schizosaccharomyce...
P45864      1 MIFRFGFVSNAMSLWDASPAKTLTFARYSKLSktER----------------------------KEALLTVTKANLRNTM 52  Bacillus subtilis ...
XP_960980 204 WKGRLGYACLNTYLRNAKPPIFSSRTCRMASIvdHRhplqfedepehhlknkpdkskepqdelgHKFVQELGLANARDIV 283 Neurospora crassa ...

Q10988    298 KLVEWNHNFGIHFMRVSSDLFPFASHAKYGYTLE-FAQSHLEEVGKLANKYNHRLTMHPGQYTQIASPREVVVDSAIRDL 376 Schizosaccharomyce...
P45864     53 RTLHYIIGHGIPLYRFSSSIVPLATHPDVMWDFVtPFQKEFREIGELVKTHQLRTSFHPNQFTLFTSPKESVTKNAVTDM 132 Bacillus subtilis ...
XP_960980 284 KMLCWNEKYGIRFLRLSSEMFPFASHPVHGYKLApFASEVLAEAGRVAAELGHRLTTHPGQFTQLGSPRKEVVESAIRDL 363 Neurospora crassa ...

Q10988    377 AYHDEILSRMKLNEQlnkdAVLIIHLGGTFEGKKETLDRFRKNYQRLSDSVKARLVLENDDVSWSVQDLLPLCQELNIPL 456 Schizosaccharomyce...
P45864    133 AYHYRMLEAMGIADR----SVINIHIGGAYGNKDTATAQFHQNIKQLPQEIKERMTLENDDKTYTTEETLQVCEQEDVPF 208 Bacillus subtilis ...
XP_960980 364 EYHDELLSLLKLPEQqnrdAVMIIHMGGQFGDKAATLERFKRNYARLSQSCKNRLVLENDDVGWTVHDLLPVCEELNIPM 443 Neurospora crassa ...

Q10988    457 VLDWHHHNIVp--gTLREGSLDLM-Pli-pTIRETWTRKGITQKQHYSESADPtAISGMKRRAHS----DRVFDFPPCDP 528 Schizosaccharomyce...
P45864    209 VFDFHHFYAN----PDDHADLNVAlP----RMIKTWERIGLQPKVHLSSPKSEqAIRSHADYVDAnfllPLLERFRQWGT 280 Bacillus subtilis ...
XP_960980 444 VLDYHHHNICfdpaHLREGTLDISdPklqeRIANTWKRKGIKQKMHYSEPCDG-AVTPRDRRKHR----PRVMTLPPCPP 518 Neurospora crassa ...

Q10988    529 TMDLMIEAKEKEQAVFELCRRYEL 552 Schizosaccharomyces pombe 972h-
P45864    281 NIDFMIEAKQKDKALLRLMDELSS 304 Bacillus subtilis subsp. subtilis str. 168
XP_960980 519 DMDLMIEAKDKEQAVFELMRTFKL 542 Neurospora crassa OR74A
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