Conserved Protein Domain Family
ung
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TIGR00628: ung 
uracil-DNA glycosylase
All proteins in this family for which functions are known are uracil-DNA glycosylases that function in base excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Links
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Statistics
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PSSM-Id: 273182
Aligned: 33 rows
Threshold Bit Score: 252.519
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
P12887   103 DDSWFPHLMD-EFKKPYFVKLKQFVTKEQAdHTVFPPAKDIYSWTRLTPFNKVKVVIIGQDPYHNFNQAHGLAFSVKPPT 181 Saccharomyces cerev...
P53765    30 NRAWMDFLQMsPFLKRKLVTLLETVAKLRTsTVVYPGEERVFSWSWLCEPTQVKVIILGQDPYHG-GQATGLAFSVSKTD 108 Equid herpesvirus t...
P12888    31 PDLWLDFLQLsPIFQRKLAAVIACVRRLRTqATVYPEEDMCMAWARFCDPSDIKVVILGQDPYHG-GQANGLAFSVAYGF 109 Epstein-Barr virus ...
CAA70280  25 PQSWIDYLQLsAFSSKKLEQIMAAVENRRKqNIVYPDSEDVMRWAFSCPPENVRVVILGQDPYHG-GQANGLAFSVHENF 103 Murine herpesvirus 68
AAB62651  28 APKWISFLSLsSFLKQKLLSLLRQIRELRLtTTVYPPQDKLMWWSHCCDPEDIKVVILGQDPYHK-GQATGLAFSVDPQC 106 Human herpesvirus 8
Q01019    27 STDWVEFLQMsQFLKQKLLQLLNCIKEKRKkAVIYPPDNKIMFWSYCCAPRDIKVVILGQDPYHG-GQGTGLAFSVSYEH 105 Herpesvirus saimiri...
P52345    33 NRDWLSFLQLsKLEITHLKHVYKLVDNDRAhLMVHPSSDNVHAWSFLCKPDNVKVVILGQDPYPD-GRGCGLAFGTVKEC 111 Human herpesvirus 6...
P50639    31 NVKWLKFLNLsDSDIVQLQNVYKLVQRDRErLIIYPDPQNVHSWSYLCSPEEIKVIIVGQDPYPD-GRGHGLAFSTVRGC 109 Human herpesvirus 7...
P16769    31 SADWIRFLSLpDHDTVLLRDTVAAVEGARQlEMVYPAPEHVHRWSYLCPPEQVRVVIVGQDPYCD-GSASGLAFGTLAGR 109 Human herpesvirus 5...
P47343    15 LPSWRAFIDE-EVKKPYFQALLEKLKALKA--TIIPKPELIFRVFSFFKPIDTKVIIFGQDPYPSPNDACGLAFAS-NNS 90  Mycoplasma genitali...

P12887   182 PAPPSLKNIYKELKQEYPDf--VEDNKVGDLTHWASQGVLLLNTSLTVRAHNANSHSKHGWETFTKRVVQLLiQdrEADG 259 Saccharomyces cerev...
P53765   109 PVPPSLRNIFLEVSACDSQ---FAVPLHGCLNNWARQGVLLLNTILTVEKGKPGSHSDLGWIWFTNYIISCLsN--ELDH 183 Equid herpesvirus t...
P12888   110 PVPPSLRNIYAELHRSLPE---FSPPDHGCLDAWASQGVLLLNTILTVQKGKPGSHADIGWAWFTDHVISLLsE--RLKA 184 Epstein-Barr virus ...
CAA70280 104 PVPPSLHNIFQELKRSVPD---FQIPPSGCLDKWAEQGVLLLNCILTVDKGRPGSHHKLGWGWFTDYVISTIsE--KNDK 178 Murine herpesvirus 68
AAB62651 107 QVPPSLRSIFRELEASVPN---FSTPSHGCLDSWARQGVLLLNTVLTVEKGRAGSHEGLGWDWFTSFIISSIsS--KLEH 181 Human herpesvirus 8
Q01019   106 SIPPSLKNIFFELQRSDPL---FHAPNHGCLNSWATQGVLLLNTVLTVEKGKAYSHSDLGWQWFTNYIISSVsE--KLSN 180 Herpesvirus saimiri...
P52345   112 SIPESLKNIFKELERSVPN---FSPPDNGCLNSWCSEGVLLLNSIFTVVHGLPMSHEAFGWQTLSYKIISKLsV--EMDS 186 Human herpesvirus 6...
P50639   110 SPPNSLKTIFAELERTIEN---FKAPAHGSLKSWCAQGVLLLNTVFTVIRGVPMSHEAIGWQVLSNRIINQLsE--KMQN 184 Human herpesvirus 7...
P16769   110 PPPPSLNNVFRELARTVDG---FQRPASGCLDAWARRGVLLLNTVFTVVHGQPGSHRHLGWQTLSNHVIRRLsE--RREH 184 Human herpesvirus 5...
P47343    91 KTPASLKRIILRLEKEYPSlkqESSWQQNFLLNWAEQGVLLLNGILTTTVFIRNAHKNWGWEEFNCNLLTFLkN--QNIK 168 Mycoplasma genitali...

P12887   260 ksLVFLLWGNNAIKLVESLlgstsvgsgskYPNIMVMKSVHPSPLSASRg-------FFG--TNHFKMINDWLYNTRG 328 Saccharomyces cerevis...
P53765   184 --CVFMLWGSKAIEKASLIn----------TNKHLVLKSQHPSPLAARSnrpslwpkFLG--CGHFKQANEYLELHGK 247 Equid herpesvirus typ...
P12888   185 --CVFMLWGAKAGDKASLIn----------SKKHLVLTSQHPSPLAQNStrksaqqkFLG--NNHFVLANNFLREKGL 248 Epstein-Barr virus (s...
CAA70280 179 --CVFMLWGNKAIEKEVLIn----------GSKHLVLKAQHPSPLASLGgysskqapFLG--CNHFSIANTYLTQHNK 242 Murine herpesvirus 68
AAB62651 182 --CVFLLWGRKAIDRTPLIn----------AQKHLVLTAQHPSPLASLGgrhsrwprFQG--CNHFNLANDYLTRHRR 245 Human herpesvirus 8
Q01019   181 --CVFMLWGTKAIEKSILId----------SSKHLVLKAQHPSPLAAASqrvgtwpkFIG--CDHFNQANKYLEEHKK 244 Herpesvirus saimiri (...
P52345   187 --LVFLLWGNHARKLSYLId----------ARKHLVLESAHPSPKvksa-----rmpFIG--CNHFVRANLFLTEHGK 245 Human herpesvirus 6 (...
P50639   185 --LVFMLWGSQARKLVSLId----------SKKHLILECAHPSPRtkgs-----ktpFIG--CGHFLKANKYLQIHNK 243 Human herpesvirus 7 s...
P16769   185 --LVFMLWGADAHTCEYLId----------RRRHLVLKSCHPSPrnt-------traFVG--NDHFILANAYLDTHYR 241 Human herpesvirus 5 s...
P47343   169 plLVFLGVQTKNFVVKSIGn----------VDGFEHLSYPHPSPLSGNL--------FLTnpNDLFKTINNWLKQHNQ 228 Mycoplasma genitalium...
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