Conserved Protein Domain Family
priA
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TIGR00595: priA 
primosomal protein N'
All proteins in this family for which functions are known are components of the primosome which is involved in replication, repair, and recombination.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Links
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Statistics
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PSSM-Id: 273162
Aligned: 8 rows
Threshold Bit Score: 737.655
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
AAC68373     238 LLFGVTGSGKTEVYLQVIRKARALGKSVILLVPEVALTIQTLSFFKMHFGSEVGVLHYK--LSDSERTQTWYKASRGLIN 315 Chlamydia trach...
P05445       250 LLEGVTGSGKTEVYFEAIAETLRRGRQALVLLPEIALAAQWPRRFADRFGAAPVQWHSQ--MGAAARRRAWRAVALGRAP 327 Rhodospirillum ...
P94461       292 LLHGVTGSGKTEIYLQSIEKVLAKGKEAIVLVPEISLTPQMVNRFKGRFGSQVAVMHSG--LSTGEKYDEWRKIHRKEVR 369 Bacillus subtil...
P74397       314 LLHGVTGSGKTEVYLQICGDRLGKGQSVLVLVPEIGLTPQLTDRFRARFGNKVAVYHSG--LSSGEKYDTWRQTLLGHEQ 391 Synechocystis s...
Q45032       155 YLFGIPGSGKTEIFIKLCEYYLALEQQVLFLIPEISLGYQIIKRIKYALNMHHKIYEYNskVPNSDKNLIWNKVKNGESL 234 Borrelia burgdo...
O83258       153 YVHGVTGSGKTEVFLRAAEAVLARGKSVIYLVPEIALTHQVLQEVYVRFGSQAAVLHSA--LSGSQRLGEWRRIQCMRHC 230 Treponema palli...
O25149       129 LLFGDTGSGKTEIYMHAIAQTLEQKKSALLLVPEIALTPQMQQRLKRVFKENLGLWHSK--LSQNQKKQFLEKLYSQEIK 206 Helicobacter py...
WP_001192661 245 LLAGVTGSGKTEVYLSVLENVLAQGKQALVMVPEIGLTPQTIARFRERFNAPVEVLHSG--LNDSERLSAWLKAKNGEAA 322 Escherichia coli

AAC68373     316 IIIGPRSAIFCPIQNLGLIIVDEEHDSAYKQSDLpPFYQARDVAVMRGKMTNATVILGSATPSLESYTNALSKKYT---- 391 Chlamydia trach...
P05445       328 VVVGARSALFLPYPDLGLIIVDEEHDSAFKQEEG-VPYNARDMAVVRARLGGFPAVLASATPSLETIENARQGRYR---- 402 Rhodospirillum ...
P94461       370 LVVGARSAIFAPFENLGMIIIDEEHESSYKQEEM-PRYHAKEVAIKRAEHHSCPVVLGSATPTLESYARAQKGVYE---- 444 Bacillus subtil...
P74397       392 IVIGTRSAIFTPLPNLGLIILDEEHDSSFKQTQLtPNYHARTVAQRRAELEQCPLILGSATPSLESWHTVHRHQNDpqrh 471 Synechocystis s...
Q45032       235 VVIGIKSVLMLPFTKLKLIIMDEEHETTYKSENI-PRFHSRHISFFLQKKFNAKFVMGSATPSLEAYHAMKNNQIK---- 309 Borrelia burgdo...
O83258       231 VVIGARSAIFAPLKRLGLVIMDEEHDSSYKSAHV-PRYHARQVAMYRCADANCPFVMGSATPSVEAWYAMLRGAVR---- 305 Treponema palli...
O25149       207 LVVGTRSALFLPLKELGLIIVDEEHDFSYKSHQS-PMYNARDLCLYLSHKFPIQVILGSATPSLNSYKRFKDKALV---- 281 Helicobacter py...
WP_001192661 323 IVIGTRSALFTPFKNLGVIVIDEEHDSSYKQQEG-WRYHARDLAVYRAHSEQIPIILGSATPALETLCNVQQKKYR---- 397 Escherichia coli

AAC68373     392 LSVLSKRASTSTPTKVFLIDMNLEMEKtr--------------------------------------------------- 420 Chlamydia trach...
P05445       403 HLVLPRRHGGAEMPEITLLDLRRAPPQkwlptdfagpggseglaapggandeaeeqkapppsptaspsptaspspmarpa 482 Rhodospirillum ...
P94461       445 LLSLKHRVNHRVMPEVSLVDMREELRNgn--------------------------------------------------- 473 Bacillus subtil...
P74397       472 YLELPERVQSRPLPPVQIVDMRAELKQgn--------------------------------------------------- 500 Synechocystis s...
Q45032       310 KIIMQNKFSQSKIEDIKIINMKKEP------------------------------------------------------- 334 Borrelia burgdo...
O83258       306 RLPLTARVAGGAPPRVEVVDVSKEA------------------------------------------------------- 330 Treponema palli...
O25149       282 -----R-LKGRYTPTQKNIIFEKTER------------------------------------------------------ 301 Helicobacter py...
WP_001192661 398 LLRLTRRAGNARPAIQHVLDLKGQKVQ----------------------------------------------------- 424 Escherichia coli

AAC68373     421 kkPFFSQTVIRSIEQRLEVGEQTIIFFNRRGFHTNVSCSSCKYTLKCPHCDMILTFHKTER----ILLCHLCNTRLSKPI 496 Chlamydia trach...
P05445       483 rlGWLSPPLITAVEETLAAGEQVLLFLNRRGYAPLTLCRSCGHRLKCPRCTAWLVEHRRDG----RLRCHHCGYQQPIPE 558 Rhodospirillum ...
P94461       474 -rSMFSVELMEKLEETIAKGEQAVLFLNKRGYSSFVMCRDCGYVPQCPHCDISMTYHRYGQ----RLKCHYCGHEEPVPH 548 Bacillus subtil...
P74397       501 -rSIFSRALQTALGELKAKQQQGILFINRRGHSTFVSCRSCGYVLECPNCDVSLSYHYVQGngqpLLRCHYCNHAEIQPK 579 Synechocystis s...
Q45032       335 --STISSELLYSIQKSLNEKRQSLIFINKRGYLKNLECNECGHIICCPNCSFGLIYHKKEN----KLLCHYCSYKTKTAS 408 Borrelia burgdo...
O83258       331 --LLLSTRLVDEIRKTKEAGYQSMLFLNRRGFSYSFQCRSCGYTLCCTQCAVPLTWHKRVG----AMQCHYCGRQEAPPE 404 Treponema palli...
O25149       302 ---FITPKLLEALQQVLDKNEQAIIFVPTRANFKTLLCQSCYKSVQCPFCSVNMSLHLKTN----KLMCHYCHFSSPIPK 374 Helicobacter py...
WP_001192661 425 --AGLAPALITRMRQHLQADNQVILFLNRRGFAPALLCHDCGWIAECPRCDHYYTLHQAQH----HLRCHHCDSQRPVPR 498 Escherichia coli

AAC68373     497 TsCPQCLGTMtLQYRGAGTEKIETLLREFFPTARTIRLDSDTTRFRGSHDALVKQFATGKADILIGTQMIAKGMHFPAVT 576 Chlamydia trach...
P05445       559 T-CPACGVADsLAPCGPGVERLAEEAAHRFPKARMDVAASDTVTGPKEAAALATRIANHDIDLIIGTQIMAKGHHFPLIT 637 Rhodospirillum ...
P94461       549 T-CPECASEH-IRFFGTGTQRVEEELTKVLPSARVIRMDVDTTSRKGAHEKLLSAFGEGKADILLGTQMIAKGLDFPNVT 626 Bacillus subtil...
P74397       580 V-CPECSSPY-LKFFGSGTQKVTEALTQEFPDLRWIRFDSDTTRRKGAHRALLDQFQRGEADLLVGTQMLTKGLDLAQIT 657 Synechocystis s...
Q45032       409 H-CPQCESKD-IKYKTYGIQLVEKELKKFLPNAKIARIDSDITKIEN--IDSINKFENKEIDILIGTQIIAKGFNFENIK 484 Borrelia burgdo...
O83258       405 S-CPCCHSFD-TRYGGVGTEYIEEAVQALFPEYRIARVDTDALRSGH-VQQTMEQFRAGKIDVLLGTQMIAKGFNFPTLR 481 Treponema palli...
O25149       375 I-CSACQSEV-LVGKRIGTMQVLKELESLLEGAKIAILDKDHTSTQKKLHNILNDFNAQKTNILIGTQMISKGHDYAKVS 452 Helicobacter py...
WP_001192661 499 Q-CPSCGSTH-LVPVGLGTEQLEQTLAPLFPGVPISRIDRDTTSRKGALEQQLAEVHRGGARILIGTQMLAKGHHFPDVT 576 Escherichia coli

AAC68373     577 LSVVLSGDSGLYIPDFRAAEQVFQLITQVTGRSGRSHLPGEVLIQTFLPQNSTISHALAQDFPAFYKEEILGRKVCNYPP 656 Chlamydia trach...
P05445       638 LVGVVDGDLGLTGGDLRASERTHQLLHQVAGRAGRAERPGRVLIQTVDPGHPVMEALASGDPALFLEVEAAERQALAMPP 717 Rhodospirillum ...
P94461       627 LVGVLSADTTLHIPDFRSAEKTFQLLTQVSGRAGRHEKPGHVIIQTYTPSHYSIQLTKTHDYETFYQHEMAHRREQSYPP 706 Bacillus subtil...
P74397       658 LVGVVAADSLLNFADYRSAERGFQTLTQVSGRAGRGEEPGQVIIQTYTPRHPVIQAVKTHNYHGFIAQELPQREMLNYPP 737 Synechocystis s...
Q45032       485 TLGIINADIGMGLPDFRSGERIFTTLSQIMGRAARFKDDNIIIIQTKNPNYYAIKYAYKNQYEQFYEEELDIRKKLNYPP 564 Borrelia burgdo...
O83258       482 LVGIACADTGLHTPDFRAAERSFALMMQVAGRAGRYVDNGLVIIQTRNPAHPAVVCAQHGDCESFYAQELAQREALCFPP 561 Treponema palli...
O25149       453 LAVVLGIDNIIKSNSYRALEEGVSLLYQIAGRSAR-QISGQVFIQS---TETDLLENFLEDYEDFL-QYELQERCELYPP 527 Helicobacter py...
WP_001192661 577 LVALLDVDGALFSADFRSAERFAQLYTQVAGRAGRAGKQGEVVLQTHHPEHPLLQTLLYKGYDAFAEQALAERRMMQLPP 656 Escherichia coli

AAC68373     657 FTRLIRCIFLGKCSDYTLKETQRVHTLIKq--nLDSQASLMEISPCGHFKVKDLFHYQFLIKTRNILVANKQIQEALa-- 732 Chlamydia trach...
P05445       718 FGRLVALVISGEDSARVQAVAAALGRAAP----MGPGLDVLGPVPAPLAMLRGRHRHRLLLKAARGVKVQPVVRHWLs-- 791 Rhodospirillum ...
P94461       707 YYYLALVTVSHEEVAKAAVTAEKIAHFLKa--nCGADTKILGPSASPIARIKDRYRYQCVIKYKQETQLSALLKKILehy 784 Bacillus subtil...
P74397       738 YGKLILLRCLGTNEREVEKTIQAIAVLCEq--lLPKTVEILGPAPASILRIAQRYRWQLLVKYPSFIKVILPLER----- 810 Synechocystis s...
Q45032       565 FNKIIRIIFRSKNEESAKQKCWEFFEKSKe--fLQEEIEHLGPSEAIMKKISKNYRYNIIYLSKSYSLLEKLVNKTk--- 639 Borrelia burgdo...
O83258       562 FVRLIRFVFRSKTRRKAKDAAYAAHALLTa--qMPLGADVLGPAACVVAQVAGSYRMQILLRAPSFPVVQQVARSf---- 635 Treponema palli...
O25149       528 FSRLCLLEFKHKNEEKAQQLSLKASQTLSs---CLEKGVTLSNFKAPIEKIASSYRYLILLRSKNPLSLIKSVHA----- 599 Helicobacter py...
WP_001192661 657 WTSHVIVRAEDHNNQHAPLFLQQLRNLILssplADEKLWVLGPVPALAPKRGGRWRWQILLQHPSRVRLQHIINGTLa-l 735 Escherichia coli

AAC68373     733 AAKLSS--KVRCIVDVDPV 749 Chlamydia trachomatis D/UW-3/CX
P05445       792 LVSIPP--GVKVQVDVDPI 808 Rhodospirillum rubrum
P94461       785 KREIEQk-HVMISIDMNPY 802 Bacillus subtilis subsp. subtilis str. 168
P74397       811 IKQICPs-SVYLDIDVDPL 828 Synechocystis sp. PCC 6803 substr. Kazusa
Q45032       640 EKVKMTs-TVYIEIDYYPI 657 Borrelia burgdorferi B31
O83258       636 LDEFRApaGVYVESDVDPV 654 Treponema pallidum subsp. pallidum str. Nichols
O25149       600 --FLKSapSIPCSVNMDPV 616 Helicobacter pylori 26695
WP_001192661 736 INTIPDsrKVKWVLDVDPI 754 Escherichia coli
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