Conserved Protein Domain Family
lysS_arch
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TIGR00467: lysS_arch 
lysyl-tRNA synthetase, archaeal and spirochete
This model represents the lysyl-tRNA synthetases that are class I amino-acyl tRNA synthetases. It includes archaeal and spirochete examples of the enzyme. All other known examples are class IIc amino-acyl tRNA synthetases and seem to form a separate orthologous set. [Protein synthesis, tRNA aminoacylation]
Links
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Statistics
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PSSM-Id: 273094
Aligned: 3 rows
Threshold Bit Score: 821.845
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q57959   1 MHWADVIAEKLIEe-rKADKYIVASGITPSGHIHVGNARETLTADAIYKGLINKGVEAELIFIADTYDPLRKLYPFLP-- 77  Methanocaldococcus ja...
O29052   1 MHWADVIAADLLK---RSNSHRIATGISPSGHIHLGNLREMVTADAIRRALLDAGGEAKIVYIADDFDPLRRRYPFLP-- 75  Archaeoglobus fulgidu...
O51603   4 AHWADFYAEKIKKekgPKNLYTVASGITPSGTVHIGNFREVISVDLVARALRDSGSKVRFIYSWDNYDVFRKVPKNMPeq 83  Borrelia burgdorferi B31

Q57959  78 KEFEQYIGMPLSEIPCPEGCCESYAEHFLRPYLESLDDLGVELTTYRADENYKKGLYDEKIKIALDNREKIMEILNKFRA 157 Methanocaldococcus ja...
O29052  76 EEYENYVGMPLCKIPDPEGCHDSYSEHFLQPFLESLEILGIPVEVRRAYQMYSEGLYENNTRIALKRRDEIARIIAEVTG 155 Archaeoglobus fulgidu...
O51603  84 ELLTTYLRQAITRVPDTRSHKTSYARANEIEFEKYLPVVGINPEFIDQSKQYTSNAYASQIKFALDHKKELSEALNEYRT 163 Borrelia burgdorferi B31

Q57959 158 NPLPDDWWPINIVCENCGKLKTKVIKYDSEKeEITYRCEiCGFENTVKp-YKGRAKLPWRVDWPARWSIFNVTIEPMGKD 236 Methanocaldococcus ja...
O29052 156 RELEERWYPFMPLCENCGRINSTRVTSFDEN-WIYYECD-CGHSGRVG--YVGGGKLTWRVDWAARWQILSITCEPFGKD 231 Archaeoglobus fulgidu...
O51603 164 SKLEENWYPISVFCTKCNRDTTTVNNYDNHY-SVEYSCE-CGNQESLDirTTWAIKLPWRIDWPMRWKYEKVDFEPAGKD 241 Borrelia burgdorferi B31

Q57959 237 HAAAGGSYDTGVLIAKEIYNYIPPKKVVYEWIQLKVgdKAiPMSSSKGVVFAVKDWTNIAHPEILRFLLLRSKP--TKHI 314 Methanocaldococcus ja...
O29052 232 HAAAGGSYDTGVRIAREIFDYEPPYPVPYEWIHLKG--KG-AMKSSKGIVLPVREMVEVIPPEIVRYITIRVKP--ERHI 306 Archaeoglobus fulgidu...
O51603 242 HHSSGGSFDTSKNIVK-IFQGSPPVTFQYDFISIKG--RGgKISSSSGDVISLKDVLEVYTPEVTRFLFAATKPntEFSI 318 Borrelia burgdorferi B31

Q57959 315 DFDLKkipdLVdEYDRLEDFYFNNKDKDelseeeqekiRIYELSt-pKIPETKPFVIPYRFCSIIAQLTYdeekedINME 393 Methanocaldococcus ja...
O29052 307 EFDPG----LG-LLDLVEEFEEKFKEKD----------RSVELS---LVGEVVYSDVPFRHLIVVGQIAN------WDLE 362 Archaeoglobus fulgidu...
O51603 319 SFDLDvi-kIYeDYDKFERIYYGVEDVKeekk--rafkRIYELSqpyMPSKRIPYQVGFRHLSVISQIFEn-----N-IN 389 Borrelia burgdorferi B31

Q57959 394 RVFEILRRNNYSIDDIDEfsmKKLKDRLLMARNWALKYGEKLVIISEDeaKEIYEKLKDKQKEWIKYFAEKLKTAEFDAL 473 Methanocaldococcus ja...
O29052 363 KALEIIERTGYTVDDVTR---RDVERRLKYARKWLEKYAPDNIKFEIP--EKVTAEFSEEEKKFLRAYAERLRSDMKPEE 437 Archaeoglobus fulgidu...
O51603 390 KILNYLKNVQE---DQKD---KLINK-INCAINWIRDFAPEDFKFSLRskFDNMEILEENSKKAINELLDFLKKNFEVAT 462 Borrelia burgdorferi B31

Q57959 474 n--LHELIYQTAKELGLNPRDAFQASYMILLGKKYGPKLGAFLATLGKDFVIRRYSLFE 530 Methanocaldococcus jannaschii DSM 2661
O29052 438 ---IHTLVYDVSKEVGIKSSKAFQAIYKAILGKTYGPRVGYFIKSLGVEWVRERIKAAL 493 Archaeoglobus fulgidus DSM 4304
O51603 463 eqdIQNEIYKISRENNIEPALFFKQIYKILIDKEKGPKLAGFIKIIGIDRFEKITSKYV 521 Borrelia burgdorferi B31
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