Conserved Protein Domain Family
lac_pts_IIC

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TIGR00394: lac_pts_IIC 
phosphotransferase system, lactose specific, IIC component
This family of proteins models the IIC domain of the phosphotransferase system (PTS) for lactose. The IIC domain catalyzes the transfer of a phosphoryl group from the IIB domain to lactose. When the IIC component and IIB components are in the same polypeptide chain they are designated IIBC. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids, Signal transduction, PTS]
Statistics
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PSSM-Id: 273055
Aligned: 4 rows
Threshold Bit Score: 663.095
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
P11162  12 GK----PFFEKLSRNIYLRAIRDGFISAMPVILFSSIFLLIAYVPNifgfKWDKGMEA----ILMKPYNYTMGLVAFLVA 83  Staphylococcus aureus
P24400   8 LK----PVFEAIAANKYISAIRDGFIACMPIIIFSSIFMMVAYVPN----AWGFYWPDnvtnTLMVAYNYSMGLLALFVA 79  Lactobacillus casei
P50976  11 GK----PFFEKISRNIYLRAIRDGFISAMPVILFSSIFLLIAYVPNifgfTWPKGIEN----MLMTPYNYTMGIIGFLVA 82  Streptococcus mutans ...
P23531   7 LIekgkPFFEKISRNIYLRAIRDGFIAGMPVILFSSIFILIAYVPN----AWGFHWSKdietFLMTPYSYSMGILAFFVG 82  Lactococcus lactis su...
P11162  84 GTTAKSLtdSFNRKLESTNQ--INFISTMQAAmcG--FLFLAS---DPAKDGgFLSAFMGTKGLLTAFLSAFVTVIVYNF 156 Staphylococcus aureus
P24400  80 GTTAKNL--TDSKNLELPKTnqINPVAVIVAS--E--ISFVILs-iLPLKTG-VDLTYMGTQGLICAYIVGLIVPNIYYV 151 Lactobacillus casei
P50976  83 GTTAKSLtdSMNRQLEKTNQ--INFISTMLASm-AgfLIMAADpakEGGFLS----AFMGTKGLLTAFIAAFITVNVYKI 155 Streptococcus mutans ...
P23531  83 GTTAKALtdSKNRDLPATNQ--INFLSTMLASm----VGFLLMa-aEPAKEGgFLTAFMGTKGLLTAFIAAFVTVNVYKV 155 Lactococcus lactis su...
P11162 157 CVKRNITIKMPKEVPPNISQVFKDLIPFSAVIIILYALDLVIRNSFKSNVAEGILKLFEPLFTAADG-WIGVTIIFGAFa 235 Staphylococcus aureus
P24400 152 CIKNNVTIKLPEQVPGNIAQSFKDLIPMGLSVTAFWLFGVGFKAATGTVLPRWIIQVLSPLFQASDSyLGLALIAGAMA- 230 Lactobacillus casei
P50976 156 CVKNNVTIRMPEEVPPNISQVFKDIFPFAFSIIILYAIQLAIKAVIGVNVAQSIGTLLAPLFSAADG-YLGITIIFGAYa 234 Streptococcus mutans ...
P23531 156 CVKNNVTIRMPEDVPPNISQVFKDLIPFTVSVVLLYGLELLVKGTLGVTVAESIGTLIAPLFSAADG-YLGITLIFGAYa 234 Lactococcus lactis su...
P11162 236 LFWFVGIHGPSIVEPAIAAITYANIEANFKLLQAGEHADKIITSGTQMFIVTFGGTGATLVVPFMFMWMTKSKRNKAIGR 315 Staphylococcus aureus
P24400 231 FFWFCGVQGPSIVQPAVVPIMIANTAANLQQYQAGQHVSHVLAMNTMDYVMNFGGTGATLVVPFIMLFAARSAQLKAVGK 310 Lactobacillus casei
P50976 235 LFWFVGIHGPSIVEPAIAAITYSNVELNAHLIHAGQHADKVITSGTQMFIVTMGGTGATLVVPFMFMWLCKSKRNKAIGR 314 Streptococcus mutans ...
P23531 235 FFWFVGIHGPSIVEPAIAAITYANIDVNLHLIQAGQHADKVITSGTQMFIATMGGTGATLIVPFLFMWICKSDRNRAIGR 314 Lactococcus lactis su...
P11162 316 ASVVPTFFGVNEPILFGAPLVLNPVFFIPFVLAPIVNVWIFKLFVEVLGMNSF--SVNLPWTTPGPLGIIMGTGFGLWSF 393 Staphylococcus aureus
P24400 311 AAFVPCTFGVNEPVLFGMPIIMNPMLFIPFLATPIVNVCLFKFFVSVLGMNSM--MYTMPWTVPGPIGILISTGFAPLAF 388 Lactobacillus casei
P50976 315 ASVVPTFFGVNEPILFGAPIVLNPVFFIPFILAPIVNVWIFKFFVDTLGMNSF--FANLPWTTPGPIGIVLGTGFAVLSF 392 Streptococcus mutans ...
P23531 315 ASVVPTFFGVNEPILFGAPIVLNPIFFVPFIFAPIVNV-WIFKFFVDT-LNMNsfSANLPWVTPGPLGIVLGTNFQVLSF 392 Lactococcus lactis su...
P11162 394 VLAITLIVVDIIIYYPFLKVYDSEILDEEEG 424 Staphylococcus aureus
P24400 389 VFVLLTLVLDVAIYFPFIRVYDSTLLAEEKA 419 Lactobacillus casei
P50976 393 VLAALLILVDTVIYYPFVKVYDEQILAEEAE 423 Streptococcus mutans UA159
P23531 393 ILAGLLVVVDTIIYYPFVKVYDEQILEEERS 423 Lactococcus lactis subsp. lactis
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