Conserved Protein Domain Family
clpX

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TIGR00382: clpX 
endopeptidase Clp ATP-binding regulatory subunit (clpX)
A member of the ATP-dependent proteases, ClpX has ATP-dependent chaperone activity and is required for specific ATP-dependent proteolytic activities expressed by ClpPX. The gene is also found to be involved in stress tolerance in Bacillus subtilis and is essential for the efficient acquisition of genes specifying type IA and IB restriction. [Protein fate, Protein folding and stabilization, Protein fate, Degradation of proteins, peptides, and glycopeptides]
Statistics
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PSSM-Id: 273047
Aligned: 6 rows
Threshold Bit Score: 664.544
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q55510         1 MPKYDS-----HLKCSFCGK--SQEQVR-----KLIAGPGVYICDECVELCNDILDEELldvppastgerdgtgqkqkkS 68  Synechocystis s...
O51557         1 MARVKGq---kVKECSFCGL--SVAELGg----NVVISNGVAICPECSKICHNLFKEKL--------------------C 51  Borrelia burgdo...
P50866         1 MFKFNEek--gQLKCSFCGK--TQDQVR-----KLVAGPGVYICDECIELCTEIVEEELgt------------------- 52  Bacillus subtil...
P44838         1 MTDKDKd-----LHCSFCGK--EKGEVD-----RLIAGTDGYICNECIELCHSMLEESHdk-----------------nL 51  Haemophilus inf...
O25926         1 ---MNEt-----LYCSFCKKpeSRDPKKrriifASNLNKDVCVCEYCIDVMHGELHKYDnsllalkr-----drlrrmeS 67  Helicobacter py...
WP_000130305   1 MTDKRKdgsgkLLYCSFCGK--SQHEVR-----KLIAGPSVYICDECVDLCNDIIREe---------------------I 52  Enterobacteriaceae
Q55510        69 GQprRRLTLEELPKPTAIKQYLDEYVIGQDEAKKVLSVAVYNHYKRLNLlerNQEIDPGd---------aVELQKSNILL 139 Synechocystis s...
O51557        52 KP--LDSKSNGLPTPKQLKDHLDMYVVGQEDAKKVLSVAVYNHYKRILK---NNKYDNG-----------IEIEKSNILL 115 Borrelia burgdo...
P50866        53 ---eEEVEFKDVPKPQEIREILNEYVIGQDQAKKSLAVAVYNHYKRINs---NSKVDD------------VELSKSNISL 114 Bacillus subtil...
P44838        52 EEsaVENEE-KLPTPHEIRAHLDDYVIGQDYAKKVLSVAVYNHYKRLRt---NYESND------------VELGKSNILL 115 Haemophilus inf...
O25926        68 SAyeEEFLLSYIPAPKELKAVLDNYVIGQEQAKKVFSVAVYNHYKRLSFkekLKKQDNQdsnvelehleeVELSKSNILL 147 Helicobacter py...
WP_000130305  53 KEvaPHRERSALPTPHEIRNHLDDYVIGQEQAKKVLAVAVYNHYKRLRn---GDTSNG------------VELGKSNILL 117 Enterobacteriaceae
Q55510       140 VGPTGSGKTLLAQTLAKILEVPFAVADATTLTEAGYVGEDVENILLRLLQVADLDVEEAQRGIIYIDEIDKIARKSENPS 219 Synechocystis s...
O51557       116 VGPTGSGKTLLAKTLAAEMNVPFAIADATTLTEAGYVGEDVENILLKLIHAAHGDVSLAEKGIIYIDEIDKIAKKNENVS 195 Borrelia burgdo...
P50866       115 IGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYDVEKAEKGIIYIDEIDKVARKSENPS 194 Bacillus subtil...
P44838       116 IGPTGSGKTLLAQTLARRLNVPFAMADATTLTEAGYVGEDVENVLQKLLQNCEYDTEKAEKGIIYIDEIDKISRKSEGAS 195 Haemophilus inf...
O25926       148 IGPTGSGKTLMAQTLAKHLDIPIAISDATSLTEAGYVGEDVENILTRLLQASDWNVQKAQKGIVFIDEIDKISRLSENRS 227 Helicobacter py...
WP_000130305 118 IGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPS 197 Enterobacteriaceae
Q55510       220 ITRDVSGEGVQQALLKMLEGTVANVPPQGGRKHPYQDCIQIDTSNILFICGGAFVGLEKVIEQRFGKKS-MGFVRPGEGP 298 Synechocystis s...
O51557       196 ITRDVSGEGVQQALLKIIEGTVANVPPRGGRKHPYEDTIEINTQNILFICGGAFVGLENIVKNRINKSS-IGFSAIEKKN 274 Borrelia burgdo...
P50866       195 ITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTNILFICGGAFDGIEQIIKRRLGQKV-IGFGADNKAA 273 Bacillus subtil...
P44838       196 ITRDVSGEGVQQALLKLIEGTIASIPPQGGRKHPQQEMVKLDTSKILFICGGAFAGLDKIIDKRTQTSTsIGFNAKVEKD 275 Haemophilus inf...
O25926       228 ITRDVSGEGVQQALLKIVEGSLVNIPPKGGRKHPEGNFIQIDTSDILFICAGAFDGLAEIIKKRTTQNV-LGFTQEKMSK 306 Helicobacter py...
WP_000130305 198 ITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDTSKILFICGGAFAGLDKVISHRVETGSgIGFGATVKAK 277 Enterobacteriaceae
Q55510       299 SKEKrtaDVLRQAEPDDLVKFGLIPEFIGRIPVMACLNPLDEDALIAILTQPRNAIVKQYQTLLGMDHVELDFQPDAVRA 378 Synechocystis s...
O51557       275 IRED---TSLKYLEMEDLIKFGLIPEFVGRLPVHSYLEKLNKEDLLRILVDPQNSIVKQYYHMFKMDNVELVFEKDALES 351 Borrelia burgdo...
P50866       274 DLEKe--DLLSKVLPEDLLRFGLIPEFIGRLPVIASLEKLDEEALVAILTKPKNALVKQFKKMLELDNVELEFEEEALSE 351 Bacillus subtil...
P44838       276 EKQQslsELFRQVEPDDLMKFGLIPEFIGRLPMIAPLSELDEDALIQILTKPKNALIKQYQALFGLEKVELDFTPEALKA 355 Haemophilus inf...
O25926       307 KEQE---AILHLVQTHDLVTYGLIPELIGRLPVLSTLDSISLEAMVDILQKPKNALIKQYQQLFKMDEVDLIFEEEAIKE 383 Helicobacter py...
WP_000130305 278 SDKAsegELLAQVEPEDLIKFGLIPEFIGRLPVVATLNELSEEALIQILKEPKNALTKQYQALFNLEGVDLEFRDEALDA 357 Enterobacteriaceae
Q55510       379 IATEAHRRKTGARALRGIVEELMLDVMYELPSREDLTHCLITREMVEKRSTAELL 433 Synechocystis sp. PCC 6803 substr. Kazusa
O51557       352 IVDEAILKNTGARGLRSILEGLLKDVMFEVPSISKAKKVVVTKESVLNADVNPLI 406 Borrelia burgdorferi B31
P50866       352 IAKKAIERKTGARGLRSIIEGIMLDVMFELPSRDDIEKCVITGATVTHGEPPRLL 406 Bacillus subtilis subsp. subtilis str. 168
P44838       356 MAKKALERKTGARGLRSIVEAVLLDTMYDLPSLENLQKVIVDESTIVDNLAPKLE 410 Haemophilus influenzae Rd KW20
O25926       384 IAQLALERKTGARGLRAIIEDFCLDIMFDLPKLK-GSEVRITKDCVLKQAEPLII 437 Helicobacter pylori 26695
WP_000130305 358 IAKKAMARKTGARGLRSIVEAALLDTMYDLPSMEDVEKVVIDESVIDGQSKPLLI 412 Enterobacteriaceae
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